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Quantitative measurement and application of droplets on physical surfaces based on LIF technology

Transportation Safety and Environment 2024年第2期6卷 104-113页

作者： fan wu Shuaixiong Zhou Qingmin Cui Renze Xu Hengkui Li Chao Yu Key Labor atory of Traffic Safety on Track of Ministry of Education School of Traffic&Transportation EngineeringCentr al South Univ ersityChangsha 410075HunanChina Joint International Research Laboratory of Key Technologies for Rail Traffic Safety School of Traffic&Transportation EngineeringCentral South UniversityChangsha 410075HunanChina School of software Henan University of EngineeringZhengzhou 451191HenanChina National&Local Joint Engineering Research Center of Safety Technology for Rail Vehicle School of Traffic&Transportation EngineeringCentral South UniversityChangsha 410075HunanChina

Contaminated surfaces play a significant role in the transmission of respiratory infectious *** address this issue,we pre-sented a novel quantitative detection method for droplets on physical surfaces,based on the laser-induced fluorescence *** proposed detection method was demonstrated in a realistic high-speed train compartment scenario by simulating the process of droplet release during passengers’breathing and *** experimental results showed that this method could offer high precision(10-1 mg/m^(2))for detecting minute substance concentrations,and its ease of operation makes it suitable for complex en-gineering *** results also revealed that under the combined effects of the indoor airflow and breathing airflow,the range of droplets released by breathing activity exceeded two rows in front of and behind the release ***,we observed that a large number of droplets settled on the seat surfaces on both sides of the same row as the releaser,with over 36%of these droplets concentrated on the backrest area of the *** the respiratory jet velocity increased,the location with the most sed-iment droplets(accounting for 8%of the total sedimentation)occurred on the seat directly in front of the releaser,and approximately 48% of the droplets were found on the back of this *** proposed method overcomes the shortcomings of existing experimental methods in quantitatively capturing the motion characteristics of droplets in complex flow fields.

关键词： quantitative measurement sediment droplets physical surfaces fluorescence measurement high-speed train compart-ment

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Effects of electron-and hole-current hysteresis on trap characterization in organo-inorganic halide perovskite

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Journal of Energy Chemistry 2023年第1期76卷 414-420,I0010页

作者： fan wu Sally Mabrouk Miaomiao Han Yanhua Tong Tiansheng Zhang Yuchen Zhang Raja Sekhar Bobba Quinn Qiao School of Science and Huzhou Key Lab of Materials for Energy Conversion and Storage Huzhou UniversityHuzhou 313000ZhejiangChina Mechanical and Aerospace Engineering Syracuse UniversitySyracuseNY13244United States

Charge trap density and carrier mobility of perovskite materials are the critical properties of perovskite solar *** space charge limited current(SCLC)method,which measures a dark current–voltage(I-V)curve of a single-carrier device has found extensive use for studying the trap density and charge carrier mobility in perovskite ***,it was found that the electron-and hole-current in organo-lead perovskite-based single-carrier device undergoes significant hysteresis under forward and reverse scanning due to the mobile *** addition,it was also observed that measuring history has a detrimental effect on hysteresis resulting in possible overestimation or underestimation of the extracted electrical values from the SCLC *** the forward/reverse scanning process,the mobile ionic defects enhance/shield the charge in the traps due to ionic charging/discharging,thereby increasing/reducing the interface barrier and net charge in the I-V scanning,which in turn affects the determination of transport properties of the *** results raise quite a few doubts over the direct application of classical SCLC measurements for the accurate characterization of intrinsic transport properties of the mixed ionicelectronic perovskite.

关键词： Organo-lead perovskite Ionic defects Space-charge-limited-current Trap density Mobility

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Ambipolar Transport Compact Models for Two-Dimensional Materials Based Field-Effect Transistors

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Tsinghua Science and Technology 2021年第5期26卷 574-591页

作者： Zhaoyi Yan Guangyang Gou Jie Ren fan wu Yang Shen He Tian Yi Yang Tian-Ling Ren the Institute of Microelectronics Tsinghua UniversityBeijing 100084China the Institute of Microelectronics and Tsinghua National Laboratory for Information Science and TechnologyTsinghua UniversityBeijing 100084China

Three main ambipolar compact models for Two-Dimensional(2D)materials based Field-Effect Transistors(2D-FETs)are reviewed:(1)Landauer model,(2)2D Pao-Sah model,and(3)virtual Source Emission-Diffusion(VSED)*** the Landauer model,the Gauss quadrature method is applied,and it summarizes all kinds of variants,exhibiting its *** the 2D Pao-Sah model,the aspects of its theoretical fundamentals are rederived,and the electrostatic potentials of electrons and holes are clarified.A brief development history is compiled for the VSED *** summary,the Landauer model is naturally appropriate for the ballistic transport of short channels,and the 2D Pao-Sah model is applicable to long-channel *** contrast,the VSED model offers a smooth transition between ultimate *** three models cover a fairly completed channel length range,which enables researchers to choose the appropriate compact model for their works.

关键词： Field-Effect Transistor(FET) compact model ambipolar transport Landauer formula Pao-Sah model virtual source

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Protein@PP-Zn nanocomplex assembled by coordination of zinc ions used for intracellular protein delivery

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Science China Chemistry 2023年第8期66卷 2354-2362页

作者： Liyun Cui Sainan Liu fan wu Hua Chen Yuanfeng Li Linqi Shi Yong Liu Rujiang Ma Key Laboratory of Functional Polymer Materials of Ministry of Education Institute of Polymer ChemistryCollege of ChemistryNankai UniversityTianjin300071China Wenzhou Institute University of Chinese Academy of SciencesWenzhou Key Laboratory of Interdiscipline and Translational MedicineWenzhou325001China Translational Medicine Laboratory the First Affiliated Hospital of Wenzhou Medical UniversityWenzhou325035China

In recent years,intracellular delivery of protein drugs has attracted great attention,and polymer-based systems have been extensively exploited to develop efficient and safe ***,efficient intracellular delivery of protein drugs remains a challenge because of the cell membrane barrier and endosome ***,we report a protein@PP-Zn nanocomplex,which consists of an imidazole-containing block polymer poly(ethylene glycol)-block-poly(β-amino ester)(PEG-b-PAE(Im),PP),zinc ions,and protein drugs,for efficient intracellular protein ***-b-PAE(Im)could conjugate proteins via the bridging effect of zinc ions which simultaneously coordinate with imidazole groups on polymer and electron donor groups,such as imidazole and primary amine groups,on protein to improve the loading stability of *** a slightly acidic environment near cancer cells,the protonation of PAE(Im)backbone increases the positive charge density of the nanocomplex and promotes *** under a more acidic environment in endosomes,further protonation of imidazole groups leads to the disintegration of the nanocomplex and the breakdown of endosomes because of the proton sponge ***,protein is released into the *** the assistance of the nanocomplex,proteins with different sizes and isoelectric points are effectively delivered into *** work provides a stable,efficient and universal strategy for intracellular protein delivery.

关键词： protein zinc ions intracellular delivery coordination polymer

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Experimental observation of spontaneous symmetry breaking in a quantum phase transition

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 34-39页

作者： Wen Ning Ri-Hua Zheng Jia-Hao Lu fan wu Zhen-Biao Yang Shi-Biao Zheng Fujian Key Laboratory of Quantum Information and Quantum Optics College of Physics and Information EngineeringFuzhou UniversityFuzhou 350108China Hefei National Laboratory Hefei 230088China

Spontaneous symmetry breaking(SSB)plays a central role in understanding a large variety of phenomena associated with phase transitions,such as superfluid and *** far,the transition from a symmetric vacuum to a macroscopically ordered phase has been substantially *** process bridging these two distinct phases is critical to understanding how a classical world emerges from a quantum phase transition,but so far remains unexplored in *** here report an experimental demonstration of such a process with a quantum Rabi model engineered with a superconducting *** move the system from the normal phase to the superradiant phase featuring two symmetry-breaking field components,one of which is observed to emerge as the classical *** results demonstrate that the environment-induced decoherence plays a critical role in the SSB.

关键词： quantum phase transition Rabi model spontaneous symmetry breaking superconducting circuit Schrodinger cat states

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Driven injection of a polymer into a spherical cavity:A Langevin dynamics simulation study

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Chinese Physics B 2021年第10期30卷 645-650页

作者： Chao Wang fan wu Xiao Yang Ying-Cai Chen Meng-Bo Luo Department of Physics Taizhou UniversityTaizhou 318000China Department of Physics Zhejiang UniversityHangzhou 310027China

The injection of a self-avoiding flexible polymer into a spherical cavity under a driving force is studied by using Langevin dynamics *** given polymer length(N)and driving force(f),the polymer can be completely injected into the cavity only when the radius of the cavity is larger than a transition radius(ReC).The dependence of ReC on N and f can be described by a scaling relation ReC∝N ^(1/3) f−δ.The value ofδchanges from 4/15 in the small f region to 1/6 in the moderate f region due to the screening of the excluded-volume interaction between *** find the complete injection time(τ)decreases monotonously with increasing the cavity radius or decreasing the polymer *** simulation results are in good agreement with the theoretical predictions from the free energy analysis and a simple kinetic model.

关键词： polymer injection simulation free energy

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Synthesis and Crystal Structure of N-[(3aR,4R,4aR,5aS,6S,6aS)-1,3-Dioxo-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)-yl]-4-(trifluoromethyl)phenylmethanimine Monohydrate

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Chinese Journal of Structural Chemistry 2010年第7期29卷 1043-1046页

作者： ZHOU Xin-Bo XIE Yun-De ZHONG wu fan Shi-Yong LI Song Institute of Pharmacology and Toxicology Academy of Military Medical Sciences Beijing 100850 China

The crystal structure of the title compound （C19H17F3N2O4, Mr = 394.35） was determined by single-crystal X-ray diffraction. The crystal belongs to monoclinic, space group C2/c with a = 28.383（6）, b = 10.355（2）, c = 12.799（3） A, β = 111.74（3）°, V= 3493.8（12） A3, Z = 8, De = 1.499 g,/cm3, λ（MoKα） = 0.71073, F（000） = 1632,μ = 0.127 mm^-1, R = 0.0412 and wR = 0.1019. In the title compound, there exist three intermolecular hydrogen interactions （O（4）...O（1）, 0（4）...0（3） and O（4）...N（1）） between water. The neighboring molecules are linked to each other generating a two-dimensional network structure via the three intermolecular hydrogen bonds and π-π interactions shaped by phen-phen with centroid distance of 4.049 A.

关键词： ST246 monohydrate crystal structure synthesis

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Mechanism of electroacupuncture on inflammatory pain: neural-immune-endocrine interactions

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Journal of Traditional Chinese Medicine 2019年第5期39卷 740-749页

作者： Li Yuan Yang Mingxiao wu fan Cheng Ke Chen Haiyong Shen Xueyong Lao Lixing School of Acupuncture Moxibustion and Tuina Shanghai University of Traditional Chinese MedicineShanghai 201203China School of Chinese Medicine The University of Hong KongHong KongChina

Nociceptive signals are transmitted by peripheral afferents to the central nervous system under pain condition, a process that involves various neurotransmitters and pathways. Electroacupuncture (EA) has been widely used as a pain management technique in clinical practice. Emerging studies have shown that EA can inhibit the induction and transmission of pain signals and, consequently, mediate anti-nociceptive and anti-inflammatory effects by rebalancing the neural-immune-endocrine interactions. This review summarizes the neural-immune- endocrine circuit including peripheral afferent and central efferent, contributing to EA-induced neuroimmune and neuroendocrine modulation in inflammatory pain models. The peripheral afferent circuit includes crosstalk among immune cells, inflammatory cytokines, peripheral nociceptors. In central efferent primarily involves the neuroinflammatory interactions between spinal nociceptive neurons and glial cells. Furthermore, the hypothalamic- pituitary-adrenal axis, sympathetic and vagal nervous may serve as an essential pathway involved in the mechanism of acupuncture-mediated analgesia within the interactions of the central, immune and endocrine systems. Overall, this review focuses on the interactions of neural-immune-endocrine in inflammatory pain, which may be underlying the mechanism of EA-induced anti-inflammatory and antinociceptive effect.

关键词： Electroacupuncture Analgesia Inflammatory pain Neural-immune-endocrine interactions Review

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Quantitative Evaluation of the Sea-level Drop at the End-Permian: Based on Reefs

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Acta Geologica Sinica(English Edition) 2003年第1期77卷 95-102页

作者： wu Yasheng and fan Jiasong Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029 Chinese Acad Sci Inst Geol & Geophys Beijing 100029 Peoples R China

The amplitude of pre-Quaternary sea level drop, H, can be calculated by usingthe formula H = D + To, where To is the original thickness from the top of the tidal deposits onthe reef core to the bottom of the tidal deposits on the reef front, or to the bottom of the ancientmeteoric vadose zone, or to the edge of the mixed-water dolostone zone. The identity and similaritybetween the sea-level drop amplitudes calculated from different reefs far away from each otherindicates that such sea-level changes are eustatic rather than relative changes. Evidence of anend-Permian sea-level drop has been found on the Changxingian (i.e. the end of the Palaeofusulinazone) reefs at Ziyun in South China, including algal laminated deposits, sabkha-related dolostone,desiccation cracks, dissolution collapse breccia. According to calculation based on the meteoricdissolution zone of the reef-core sequence at Ziyun, Guizhou province, the amplitude of thesea-level drop at the end-Permian is about 89.3 m. Calculation via the dolomitized upper part of theChangxingian reef in Lichuan, Hubei Province, yields an 88.9 m amplitude of the sea-level drop atthe end-Permian. Comparison shows that the sea-level drop recorded in the two distantly locatedreefs may be of eustatic type. So the amplitude of the sea level drop of the Tethys Sea at theend-Permian might be at least 89.3 m.

关键词： sea-level drop eustatic reef Permian Changxingian

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Power spectral density measurement for large aspheric surfaces

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Frontiers of Optoelectronics 2008年第Z1期1卷 197-200页

作者： Wei CHEN Hanmin YAO fan wu Shibin wu Qiang CHEN Xi'an University of Science and Technology Institute of Optics and Electronics Chinese Academy of Sciences

To ensure the safe and normal operation of the whole optical system, it is important to test and evaluate the quality of optical components. The article explores the advantages and disadvantages of general parameters used in aspheric surface testing, the composition of the system,the principle of operation and the design of related power spectral density(PSD) software used in testing large aspheric surfaces with Shack-Hartmann and phase shifting interferometer. The results indicate that PSD can give the spatial frequency distribution of the wavefront aberration when large aperture phase shifting interferometer is used as an instrument to test the wavefront, and this can also be applied as an evaluation standard in testing the quality of optical components. In addition, this paper describes the test results of optical components in the size of 64 mm × 64 mm.

关键词： power spectral density (PSD) optic testing large aspheric

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