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Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis

World Journal of Gastroenterology 2013年第40期19卷 6842-6848页

作者： Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh Young woo Choi Young woo Kang woo suk chung Division of Gastroenterology and Hepatology Department of Internal MedicineKonyang University College of MedicineDaejeon 302-718South Korea Department of Diagnostic Radiology Konyang University College of MedicineDaejeon 302-718South Korea

AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic ***:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ***:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan.

关键词： Acute abdomen Differential diagnosis Appendix epiploica Colonic diverticulitis Multidetector computed tomography

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TMEM39A and TMEM131 facilitate bulk transport of ECM proteins through large COPII vesicle formation

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Journal of Genetics and Genomics 2025年第2期52卷 189-203页

作者： Jee Young Sung Ga-Eun Lim Jarim Goo Kyung Jin Jung Jeong Min chung Hyun suk Jung Yong-Nyun Kim Jaegal Shim Cancer Metastasis Branch Research InstituteNational Cancer Center323 Ilsan-roGoyang-siGyeonggi-do10408Republic of Korea Experimental Clinical Research Center Biomedical Research InstituteSeoul National University Bundang HospitalSeongnamGyeonggi-do13620Republic of Korea Department of Biochemistry College of Natural SciencesKangwon National UniversityChuncheonKangwon-do24341Republic of Korea

The growth of Caenorhabditis elegans involves multiple molting processes,during which old cuticles are shed and new cuticles are rapidly *** process requires the regulated bulk secretion of cuticle *** transmembrane protein-39(TMEM-39)mutant exhibits distinct dumpy and ruptured phenotypes characterized by notably thin ***-39 primarily co-localizes with the coat protein II complex(COPII)in large vesicles rather than small COPII *** TMEM-39-associated large vesicles(TMEM-39-LVs)form robustly during the molting period and co-localize with various extracellular matrix components,including BLI-1 collagen,BLI-3 dual oxidase,and *** immunoprecipitation using TMEM39A-FLAG and proteomics analysis in human sarcoma cells,we identify TMEM39A-associated proteins,including *** of TMEM131 results in reduced TMEM39A-LV formation and collagen secretion in both *** and human sarcoma cells,indicating a cooperative role between TMEM39A and TMEM131 in the secretion of extracellular components through the formation of large COPII *** the conservation of TMEM39A and its associated proteins between *** and humans,TMEM39A-LVs may represent a fundamental machinery for rapid and extensive secretion across metazoans.

关键词： Bulk secretion Collagen COPII ECM TMEM39A TMEM131

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Formation of FeMo_2B_2 phase in boron containing 9Cr-1.5Mo ferritic steels

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Rare Metals 2006年第Z2期25卷 213-219页

作者： JUNG woo-Sang HONG suk-woo SONG Sang-Min SOOK-In Kwun chung Soon-Hyo Materials Science & Technology Division Korea Institute of Science & Technology Seoul 136-791 Korea Department of Materials Science and Engineering Korea University Seoul 136-713 Korea

The segregation and diffusion of boron during heat treatments were studied. The influence of boron contents, aging time and applied stress on FeMo2B2 formation was also studied. Finally, the effects of boron contents and FeMo2B2 formation on the high temperature strength were studied. Boron atoms were segregated to prior austenite grain boundary during normalizing treatment. And these boron atoms were slowly diffused into the grain interior during tempering and aging at 700 ℃. The FeMo2B2 phase was only formed after 1,000 h aging at 700 ℃ in alloy containing 196 ppm boron. The formation of FeMo2B2 phase is accelerated by the applied stress. It was expected that the formation of FeMo2B2 is closely related to the redistribution of boron atoms. The tensile strengths at 700 ℃ are increased with the increase of boron contents. However, the formation of FeMo2B2 phase results in lower tensile strength.

关键词： 9Cr-1.5Mo ferritic steels precipitation behavior boron effect FeMo2B2 phase tensile strength

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Grade-4 commercially pure titanium with ultrahigh strength achieved by twinning-induced grain refinement through cryogenic deformation

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Journal of Materials Science & Technology 2021年第7期66卷 193-201页

作者： Seong-woo Choi Jae sukjeong Jong woo Won Jae Keun Hong Yoon suk Choi Titanium Department.Korea Institute of Materials Science Changwon51508Republic of Korea School of Materials Science and Engineering Pusan National UniversityPusan.46241Republic of Korea Materials and Manufacturing Development Team Doosan Heavy Industries and ConstructionChangwon51711Republic of Korea

The yield strength of commercially pure(CP) Ti of ASTM grade 4, the strongest among all the CP-Ti grades, is too low for structural applications that require high-strength materials. Here, we demonstrate the strengthening of grade-4 CP Ti by cryogenic-temperature rolling(CTR), which enables deformation twinning in grade-4 CP Ti to achieve twinning-induced grain refinement. CTR activated {11.22} twinning and {10.12} twinning, which are the most common twinning systems in pure Ti, whereas room-temperature rolling(RTR) did not activate any twinning system. CTR with imposing an area reduction of just 30% significantly increased the yield strength of the CP Ti to 946 MPa, which is not achievable through typical processes performed at or above room temperature and is comparable to that of commercial Ti-6 Al-4 V. The significant increase in strength was due to microstructural strengthening caused by twinning-induced grain refinement, combined with dislocation accumulation. In contrast to RTR, CTR greatly increased the stress concentration at grain boundaries(GBs), which caused the unusual activation of twinning in the grade-4 CP Ti by facilitating twin nucleation at GBs. The stress concentration increased because CTR activated the slip to a lesser extent compared to RTR, thereby reducing the strain compatibility between neighboring grains. These results will contribute to development of ultrahigh-strength CP Ti and may thereby extend its use to structural applications that require high-strength materials.

关键词： Titanium Twinning Cryogenic deformation Grain refinement Tensile properties

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Graphene quantum dots/Ni(OH)_(2) nanocomposites on carbon cloth as a binder-free electrode for supercapacitors

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Journal of Materials Science & Technology 2020年第23期58卷 73-79页

作者： Yiwen Hong Jingli Xu Jin suk chung Won Mook Choi School of Chemical Engineering University of Ulsan93 Daehak-ro Nam-guUlsan44610Republic of Korea College of Chemistry and Chemical Engineering Shanghai University of Engineering ScienceLongTeng Road 333201620ShanghaiPR China

Graphene quantum dots(GQDs)/Ni(OH)_(2) composites on carbon cloth(G-NH//CC) are prepared through simple hydrothermal reactions. The resulting G-NH//CC is employed as a binder-free electrode of supercapacitors. Due to the enhanced electrical conductivity and efficient ion transport by the addition of GQDs, the G-NH//CC electrode exhibits enhanced electrochemical performances. Specifically, the GNH//CC delivers a maximum specific capacitance of 1825 F g^(-1) at a current density of 1 A g^(-1) as well as a good cycle stability of 83.5 % capacity retention after 8000 cycles. Additionally, all-solid-state symmetric supercapacitor(SSC) is assembled with G-NH//CC composites as both positive and negative *** fabricated SSC exhibits a high energy density of 80.8 Wh kg^(-1)at a power density of 2021 W kg^(-1). The present study provides a facile and efficient strategy to prepare high-performance electrode materials for advanced electrochemical energy storage devices.

关键词： Graphene quantum dots Ni(OH)_(2) Carbon clothes Symmetric supercapacitors

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THERMODYNAMIC MODELING OF NANOSCALE FERROELECTRIC SYSTEMS

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Acta Mechanica Solida Sinica 2009年第6期22卷 524-549页

作者： Yue Zheng Biao Wang chung-Ho woo State Key Laboratory of Optoelectronic Materials and Technologiez/Institute of Optoelectronic and FunctionalComposite Materials School of Physics and Engineering Sun Yat-sen University Guangzhou 510275 China Department of Electronic and Information Engineering The Hong Kong Polytechnic University Hong Kong SAR China

Thermodynamic models formulated based on the Landau free-energy expansion are popular and well suited to studies involving properties of the ferro/para-electric transition, or near it. Indeed, the general nature of thermodynamics, from which the strength of the model is derived, allows a valid model to be constructed based on simple functional forms with parameters fitted to experiments, by passing the mechanistic complexity. Despite inaccuracy due to the neglect of fluctuations, this approach has been proven effective and powerful for recent research development of ferroelectrics in nanoscale. Efforts in some important works have recently faced much challenge, when free-energy contributions have to be incorporated to account for the presence of depolarization fields, surfaces and other defects. To minimize the problems with mechanistic obscurity, it is of paramount importance that the electromagnetics, mechanics and thermodynamics involved are accounted for explicitly and with full self-consistency. It is important that the free-energy functional of nanoscale ferroelectric systems, such as ferroelectric thin films （FTF）, bilayers （FB）, superlattices （FS）, nanowires （FNW）, nanotubes （FNT） and tunneling junctions （FTJ） etc., must be derived thermodynamically from first principles.

关键词： ferroelectrics nanoscale thin film superlattice nanowire nanotube tunneling junction mechanical load

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Accelerating Falcon Post-Quantum Digital Signature Algorithm on Graphic Processing Units

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Computers, Materials & Continua 2023年第4期75卷 1963-1980页

作者： Seog chung Seo Sang woo An Dooho Choi Kookmin University Seoul02707Korea Telecommunications Technology Association(TTA) Gyeonggi-do13591Korea Korea University Sejong30019Korea

Since 2016,the National Institute of Standards and Technology(NIST)has been performing a competition to standardize post-quantum cryptography(PQC).Although Falcon has been selected in the competition as one of the standard PQC algorithms because of its advantages in short key and signature sizes,its performance overhead is larger than that of other lattice-based *** study presents multiple methodologies to accelerate the performance of Falcon using graphics processing units(GPUs)for server-side *** GPU porting significantly degrades performance because the Falcon reference codes require recursive functions in its sampling ***,an iterative sampling approach for efficient parallel processing is *** this study,the Falcon software applied a fine-grained execution model and reported the optimal number of threads in a thread ***,the polynomial multiplication performance was optimized by parallelizing the number-theoretic transform(NTT)-based polynomial multiplication and the fast Fourier transform(FFT)-based ***,dummy-based parallel execution methods have been introduced to handle the thread divergence *** presented Falcon software on RTX 3090 NVIDA GPU based on the proposed methods with Falcon-512 and Falcon-1024 parameters outperform at 35.14,28.84,and 34.64 times and 33.31,27.45,and 34.40 times,respectively,better than the central processing unit(CPU)reference implementation using Advanced Vector Extensions 2(AVX2)instructions on a Ryzen 95900X running at 3.7 GHz in key generation,signing,and verification,***,the proposed Falcon software can be used in servers managing multiple concurrent clients for efficient certificate verification and be used as an outsourced key generation and signature generation server for Signature as a Service(SaS).

关键词： DSA Falcon GPU CUDA software optimization

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A Power-Aware Branch Predictor by Accessing the BTB Selectively

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Journal of Computer Science & Technology 2005年第5期20卷 607-614页

作者： Cheol Hong Kim Sung woo chung Chu Shik Jhon Mobile System Laboratory Department of Electrical Engineering and Computer Science Seoul National University Seoul 151-742 Korea Department of Computer Science University of Virginia Charlottesville Virginia 22904 U.S.A.

Microarchitects should consider power consumption, together with accuracy, when designing a branch predictor, especially in embedded processors. This paper proposes a power-aware branch predictor, which is based on the gshare predictor, by accessing the BTB （Branch Target Buffer） selectively. To enable the selective access to the BTB, the PHT （Pattern History Table） in the proposed branch predictor is accessed one cycle earlier than the traditional PHT if the program is executed sequentially without branch instructions. As a side effect, two predictions from the PHT are obtained through one access to the PHT, resulting in more power savings. In the proposed branch predictor, if the previous instruction was not a branch and the prediction from the PHT is untaken, the BTB is not accessed to reduce power consumption. If the previous instruction was a branch, the BTB is always accessed, regardless of the prediction from the PHT, to prevent the additional delay/accuracy decrease. The proposed branch predictor reduces the power consumption with little hardware overhead, not incurring additional delay and never harming prediction accuracy. The simulation results show that the proposed branch predictor reduces the power consumption by 29-47%.

关键词： branch predictor BTB embedded processor low power design PHT

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A fast and simple system performance emulator for enhanced solid state disks:a case study of long read operations

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Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第6期11卷 418-424页

作者： Do Yeun KIM Chanik PARK Eui-Young chung Sung woo chung Division of Computer and Communication Engineering Korea University Seoul 13-713 Korea Samsung Electronics Yongin-City Kyunggi-Do 446-701 Korea School of Electrical and Electronic Engineering Yonsei University Seoul 120-749 Korea

In this paper, we propose a fast and simple system emulator, called a system performance emulator(SPE), to evaluate long read *** SPE estimates how much system-wide performance is enhanced by using a faster solid state disk(SSD).By suspending a CPU for a certain time during direct memory access(DMA) transfer and subtracting this suspended time from the total DMA time, the SPE estimates the improvement in system performance expected from an enhanced SSD prior to its *** also examine the relation between storage performance and system performance using the SPE.

关键词： Solid state disk(SSD) Performance emulator System performance Direct memory access(DMA) Operating system

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Molecular targeted therapy for hepatocellular carcinoma:Current and future

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World Journal of Gastroenterology 2013年第37期19卷 6144-6155页

作者： Jung woo Shin Young-Hwa chung Department of Internal Medicine University of Ulsan College of Medicine Ulsan University Hospital Department of Internal Medicine University of Ulsan College of MedicineAsan Medical Center

Hepatocellular carcinoma(HCC)is one of the most frequent tumors *** majority of HCC cases occur in patients with chronic liver *** regular surveillance to detect small HCC in these patients,HCC is often diagnosed at an advanced *** HCC is highly resistant to conventional systemic therapies,the prognosis for advanced HCC patients remains *** introduction of sorafenib as the standard systemic therapy has unveiled a new direction for future research regarding HCC ***,given the limited efficacy of the drug,a need exists to look beyond *** molecular targeted agents that inhibit different pathways involved in hepatocarcinogenesis are under various phases of clinical development,and novel targets are being assessed in *** review aims to summarize the efforts to target molecular components of the signaling pathways that are responsible for the development and progression of HCC and to discuss perspectives on the future direction of research.

关键词： Hepatocellular carcinoma Targeted therapy Molecular agents Sorafenib

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