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第三世界生态高峰会

作者： Tam Nora. wong yuk-shan Center for Plant Ecology and Biodiversity Conservation.Institute of Botany.Chinese Academy of Sciences Xiangshan Beijing China School of Biological Sciences.Xiamen University.Xiamen.Fujian.China. Department of Biology and Chemistry City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong. Guangxi Mangrove Research Center Beihai.Guangxi China. Office of the Vice President for Administration and Business.Hong Kong University of Science and Technology Clearwater Bay Kowloon.Hong Kong.

In this paper,we discussed the ecology and economy of mangrove ecosystems in southeastern China where mangroves have been coexisting with people for several thousand *** occur naturally in southeastern China,mainly in Hainan,Guangxi, Guangdong,Hong Kong,and *** are 36 species of mangrove species in China,acconnting for 43% of the total number of species found in the *** China,mangroves are often used by local people as wood,food,medicine and aquaculture farms,in addition to their functions in protecting coastal lines,proving feeding grounds for many marine organisms and serving as natural filters for landward *** last few decades,the population boom and rapid economic development have greatly reduced mangrove areas. Research during last 30 years have not only improved our understanding of mangrove ecology but also educated publics and governmental officers about the importance of mangrove ecosystems. Since 1980s,great efforts have been made in China to protect mangrove forests and their ecological *** has already established mangrove ecosystems as high priority areas for improved environmental and living resource ***'s Biodiversity Conservation Action Plan issued in 1995 included its“Action Plan for Marine Biodiversity Protection in China”and called for increasing the area for mangrove conservation.“Marine Environmental Protection Law”promulgated in 1982 and revised in 1999 has granted mangrove protection of highest *** far,total of 11 natural mangrove conservation areas have been established,which occupy more than 20000 ha coastal *** recent years,replanting of mangroves by government authorities has taken place in areas where natural mangroves were destroyed but introducing fast-growing species from other countries may cause other ecological consequences. Multi-disciplinary research and more systematic protection strategies are urgently needed.

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Enantioselective iridium-catalyzed allylic substitution with a Reformatsky reagent: direct construction of β-stereogenic homoallylic esters

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Science China Chemistry 2024年第11期67卷 3791-3797页

作者： Debasis Pal Kirana D.Veeranna yuk Fai wong P.Andrew Evans Department of Chemistry Queen's University Xiangya School of Pharmaceutical Sciences Central South University

The Reformatsky reagent derived from ethyl bromoacetate circumvents the challenge associated with the direct regio-and enantioselective iridium-catalyzed allylic alkylation with an unstabilized aliphatic ester enolate. Notably, this work represents the first example of using a Reformatsky reagent in a metal-allyl reaction, which permits the direct construction of enantioenriched β-stereogenic homoallylic esters without preactivation of the pronucleophile or post-reaction modification of the product(e.g., thermal decarboxylation of a 1,3-dicarbonyl). Moreover, the process allows the coupling of a broad range of sterically and electronically diverse electrophiles bearing aryl, heteroaryl and alkenyl derivatives, including the significantly more challenging alkyl-substituted allylic carbonates. The versatility of the ester product is exemplified by a series of functional group manipulations and the development of a concise and efficient enantioselective total synthesis of the natural product,(+)-descurainolide A. Finally, mechanistic studies indicate that the zinc enolate behaves as a soft nucleophile that undergoes outer-sphere alkylation.

关键词： allylic substitution asymmetric catalysis mechanistic studies natural product synthesis Reformatsky reagent

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Bioaccumulation of Nickel by Various Scenedesmus Species in Culture Solution Containing Nickel

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Acta Botanica Sinica 2002年第8期44卷 978-982页

作者：胡章立黄玉山谭凤仪深圳大学生命科学学院深圳518060 香港城市大学生物及化学系海岸污染与保护中心

Sixteen Scenedesmus species or strains have been employed to investigate the maximum capacity of nickel (Ni) accumulation in 10 mg/L Ni solution. The results showed that the capacity of accumulating Ni from aqueous solution in 16 Scenedesmus species or strains showed the diversity. S. quadricauda freshwater algae culture collection of the Institute of Hydrobiology (FACHB) 44 and S. quadricauda FACHB 506 performed much more capacity of Ni accumulation than other species such as Scenedesmus sp. FACHB 416 and Scenedesmus sp. FACHB 489. Sequestration of Ni ions from aqueous solution was very efficient (26.7 mg Ni/g dry weight, in the 100 mg/L Ni solution) in S. quadricauda FACHB 44. The kinetics of Ni binding indicated that Ni bioaccumulation, in algal cell of S. quadricauda FACHB 44, possessed a rapid biosorption (5 min) and an slow bioaccumulation (2-3 h). More than 70% of Ni binding in algal cell were accumulated by biosorption and the remaining 20%-30% were bioaccumulated by energy_consumed transportation. It is much more higher ratio of energy_consumed transportation in S. quadricauda FACHB 44 than in other algae. Both the transmission electron microscope (TEM) and the energy_dispersive X_ray (EDX) microanalyses also revealed the different mechanisms of bioaccumulation in the various subcellular regions: a very fast adsorption in the cell wall; and a time_dependent absorption in protoplasm, specially in starch and chromatin.

关键词： bioaccumulation Scenedesmus nickel (Ni)

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非胎生红树植物繁殖体特征及潮间带分带现象

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Acta Botanica Sinica 2004年第8期46卷 896-906页

作者：叶勇卢昌义黄玉山谭凤仪厦门大学海洋环境科学教育部重点实验室，厦门361005 香港城市大学生物及化学系，香港

研究了香港4种非胎生红树植物榄李(Lumnitzera racemosa(Jack．)Voigt．)、银叶树(Heritiera littoralis(Drgand．)Ait．)、海漆(Excoecaria agallocha L．)和老鼠筋(Acanthus ilicifotius L．)的繁殖体特征和萌发技术，并分析了其在潮间带分带的决定因素。所有直接种植的新鲜榄李繁殖体均不能萌发，但经湿润贮藏35d和50d的繁殖体能萌发，说明该物种具有种子休眠的特性。榄李萌发率随盐度升高而下降，盐度高于25则不能萌发。银叶树繁殖体果壳的去除可加速其萌发。海漆和老鼠筋的繁殖体分别在2d和3d开始萌根。在繁殖体萌发方面，老鼠筋的耐盐性比榄李强。4种非胎生红树植物对潮间带不稳定环境的适应方式有：(1)繁殖体的寿命较长，如榄李和银叶树；(2)萌根速度快，如海漆和老鼠筋；(3)具有沉性繁殖体，如榄李。繁殖体的悬浮性是决定这4种非胎生红树植物潮间带分带的最重要因素：榄李因具有沉性繁殖体而自然分布于最靠海的区域，而银叶树、海漆和老鼠筋因具有浮性繁殖体而更靠陆岸分布。对于繁殖体悬浮性相同的物种，萌根速度是影响潮间带分带的重要因素：完整的银叶树繁殖体需要108d才能萌根，因而分布于最靠陆岸的区域，而海漆和老鼠筋因萌根速度快而在相对更靠海的区域分布。环境盐度、繁殖体大小、动物啃食和幼苗大小等因素则不能解释香港非胎生红树植物在潮间带的分带现象。

关键词：榄李银叶树海漆红树林潮间带分带种子休眠

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Dual innervation method to preserve erectile function following prostatectomy

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第3期6卷 159-160页

作者： Nadia Hui shan Sim Allen Sim Dayna Sim Bien-Keem Tan Allen Wei-Jiat wong Plastic Reconstructive and Aesthetic Surgery ServiceSengkang General Hospital544886Singapore Department of Urology Mount Alvernia Hospital Singapore574623Singapore Department of General Surgery Sengkang General Hospital544886Singapore Department of Plastic Reconstructive and Aesthetic SurgerySingapore General Hospital169608Singapore

Prostate cancer is the second most prevalent cancer in ***-assisted radical prostatectomy(RARP)has altered the landscape of prostate cancer *** the excellent oncological outcomes associated with RARP,the rate of erectile dysfunction(ED)remains *** repair of disrupted cavernous nerves with interpositional nerve grafts has been described;however,the outcomes have been *** hypothesize that this is attributed to Schwann cell atrophy and axonal regeneration limitations caused by long nerve *** proposed the use of nerve transfer to support axonal regrowth via an inter-positional graft with additional donor axons.A cadaveric study was performed to evaluate the anatomical feasibility of a vastus lateralis nerve(VLN)transfer to the distal recipient cavernous nerve *** VLN is long with multiple branching patterns that allow tension-free coaptation of the cavernous *** postulate that a dual innervation method using VLN nerve transfer together with interpositional nerve graft repair of the transacted cavernous nerves may improve the outcomes of ED post-RARP.

关键词： Erectile dysfunction Prostatectomy Interposition nerve graft Nerve transfer Vastus lateralis nerve

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藻类对多环芳香烃(PAHs)的富集和代谢(英文)

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武汉植物学研究 2005年第3期23卷 291-298页

作者：雷安平胡章立黄玉山谭凤仪深圳大学生命科学学院深圳518060 香港城市大学生物与化学系

概述了藻类对PAHs的富集和代谢的研究进展。环境中多环芳香烃(PAHs)的污染能导致严重的健康问题,利用生物特别是微生物去除污染环境中的PAHs是一项新的技术。藻类对PAHs的富集与有机污染物的类型、藻类的种类及藻类的生物量有关,活细胞... 详细信息

概述了藻类对PAHs的富集和代谢的研究进展。环境中多环芳香烃(PAHs)的污染能导致严重的健康问题,利用生物特别是微生物去除污染环境中的PAHs是一项新的技术。藻类对PAHs的富集与有机污染物的类型、藻类的种类及藻类的生物量有关,活细胞和死细胞对PAHs均有富集能力。还阐述了PAHs在真菌、细菌和藻类体内代谢的途径以及代谢过程中起关键作用的酶,PAHs在藻类中的代谢途径和细菌及真菌都不同,谷胱甘肽转移酶(GST)在藻类代谢PAH过程中起重要作用,但细胞色素P450酶所起的作用则不详。

关键词：多环芳香烃(PAHs) 生物富集代谢藻类

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Effectiveness of post-COVID-19 primary care attendance in improving survival in very old patients with multimorbidity:a territory-wide target trial emulation

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Family Medicine and Community Health 2024年第3期12卷 25-35页

作者： Cuiling Wei Vincent Ka Chun Yan Camille Maringe Wenxin Tian Rachel Yui Ki Chu Wenlong Liu Boyan Liu Yuqi Hu Lingyue Zhou Celine Sze Ling Chui Xue Li Eric yuk Fai Wan Ching Lung Cheung Esther Wai Yin Chan William Chi Wai wong Ian Chi Kei wong Francisco Tsz Tsun Lai Centre for Safe Medication Practice and Research Department of Pharmacology and PharmacyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong Department of Health Services Research and Policy Faculty of Public Health and PolicyLondon School of Hygiene and Tropical MedicineLondonUK School of Nursing Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong School of Public Health Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong Laboratory of Data Discovery for Health(D24H) Hong KongHong Kong Advanced Data Analytics for Medical Science(ADAMS)Limited Hong KongHong Kong Department of Medicine School of Clinical MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong Department of Family Medicine and Primary Care School of Clinical MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong Department of Pharmacy The University of Hong Kong-Shenzhen HospitalShenzhenPeople's Republic of China Aston Pharmacy School Aston UniversityBirminghamUK School of Pharmacy Macao University of Science and TechnologyTaipaMacao

Objectives Older individuals with multimorbidity are at an elevated risk of infection and complications from *** of post-COVID-19 interventions or care models in reducing subsequent adverse outcomes in these individuals have rarely been *** study aims to examine the effectiveness of attending general outpatient within 30 days after discharge from COVID-19 on 1-year survival among older adults aged 85 years or above with *** Retrospective cohort study emulating a randomised target trial using electronic health *** We used data from the Hospital Authority and the Department of Health in Hong Kong,which provided comprehensive electronic health records,COVID-19 confirmed case data,population-based vaccination records and other individual characteristics for the *** Adults aged 85 years or above with multimorbidity who were discharged after hospitalisation for COVID-19 between January 2020 and August *** Attending a general outpatient within 30 days of last COVID-19 discharge defined the exposure,compared to no outpatient *** outcome measures Primary outcome was all-cause mortality within one *** outcomes included mortality from respiratory,cardiovascular and cancer *** A total of 6183 eligible COVID-19 survivors were included in the *** all-cause mortality rate following COVID-19 hospitalisation was lower in the general outpatient visit group(17.1 deaths per 100 person-year)compared with non-visit group(42.8 deaths per 100 person-year).After adjustment,primary care consultations within 30 days after discharge were associated with a significantly greater 1-year survival(difference in 1-year survival:11.2%,95%CI 8.1%to 14.4%).We also observed significantly better survival from respiratory diseases in the general outpatient visit group(difference in 1-year survival:6.3%,95%CI 3.5%to 8.9%).In a sensitivity analysis for different grace period lengths

关键词： morbidity visit records

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Effects of SARS-CoV-2 infection on incidence and treatment strategies of hepatocellular carcinoma in people with chronic liver disease

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World Journal of Hepatology 2024年第2期16卷 211-228页

作者： Lung-Yi Mak Matthew Shing Hin Chung Xue Li Francisco Tsz Tsun Lai Eric yuk Fai Wan Celine Sze Ling Chui Franco Wing Tak Cheng Esther Wai Yin Chan Ching Lung Cheung Ivan Chi Ho Au Xi Xiong Wai-Kay Seto Man-Fung Yuen Carlos King Ho wong Ian Chi Kei wong Department of Medicine The University of Hong KongHong KongChina State Key Laboratory of Liver Research The University of Hong KongHong KongChina Department of Pharmacology and Pharmacy The University of Hong KongHong KongChina Laboratory of Data Discovery for Health(D24H) Hong Kong Science and Technology ParkHong KongChina Department of Family Medicine and Primary Care The University of Hong KongHong KongChina School of Nursing The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina Research Department of Practice and Policy University College LondonLondon WC1E 6BTUnited Kingdom Aston School of Pharmacy Aston UniversityBirmingham B47ETUnited Kingdom

BACKGROUND Chronic liver disease(CLD)was associated with adverse clinical outcomes among people with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** To determine the effects of SARS-CoV-2 infection on the incidence and treatment strategy of hepatocellular carcinoma(HCC)among patients with *** A retrospective,territory-wide cohort of CLD patients was identified from an electronic health database in Hong *** with confirmed SARS-CoV-2 infection[coronavirus disease 2019(COVID-19)+CLD]between January 1,2020 and October 25,2022 were identified and matched 1:1 by propensity-score with those without(COVID-19-CLD).Each patient was followed up until death,outcome event,or November 15,*** outcome was incidence of *** outcomes included all-cause mortality,adverse hepatic outcomes,and different treatment strategies to HCC(curative,non-curative treatment,and palliative care).Analyses were further stratified by acute(within 20 d)and post-acute(21 d or beyond)phases of SARS-CoV-2 *** rate ratios(IRRs)were estimated by Poisson regression *** Of 193589 CLD patients(>95%non-cirrhotic)in the cohort,55163 patients with COVID-19+CLD and 55163 patients with COVID-19-CLD were included after 1:1 propensity-score *** 249-d median follow-up,COVID-19+CLD was not associated with increased risk of incident HCC(IRR:1.19,95%CI:0.99-1.42,P=0.06),but higher risks of receiving palliative care for HCC(IRR:1.60,95%CI:1.46-1.75,P<0.001),compared to *** both acute and post-acute phases of infection,COVID-19+CLD were associated with increased risks of allcause mortality(acute:IRR:7.06,95%CI:5.78-8.63,P<0.001;post-acute:IRR:1.24,95%CI:1.14-1.36,P<0.001)and adverse hepatic outcomes(acute:IRR:1.98,95%CI:1.79-2.18,P<0.001;post-acute:IRR:1.24,95%CI:1.13-1.35,P<0.001),compared to *** Although CLD patients with SARS-CoV-2 infection were not associated with increased risk of HCC,they

关键词： SARS-CoV-2 infection Chronic liver disease Long COVID Post-COVID-19 syndrome Cirrhosis Hepatocellular carcinoma

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The“Ukiyo”of Moxibustion Reflected in the Ukiyo-e

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Chinese Medicine and Culture 2024年第3期7卷 213-221页

作者： JIANG shan Hong Foong wong(Translated) School of Medical Humanities and Social Sciences Peking Union Medical CollegeBeijing 100730China International Research Center for Japanese Studies Kyoto 610-1192Japan 不详

Ukiyo-e(浮世絵)was a genre of popular art during the Edo and Meiji periods in ***,which was originally introduced from China,was also in its heyday and became one of the popular topics for ukiyo-e artists at that *** the images as historical evidence perspective,this article focuses on the moxibustion used in daily life in Japan depicted in the ukiyo-e *** the perspective of acu-moxa therapy,one may identify some specific issues in the acupoint selection,leading to the discovery of special application of moxibustion used by the group of yūjo(遊女)at that *** article concludes by exploring gender issues in ukiyo-e arts and the implications of punishment attached to moxibustion treatment.

关键词： Moxibustion Ukiyo-e(浮世絵) Edo period Utagawa Kunisada(歌川国貞)

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Characterization,expression dynamics,and potential function of OPA1 for regulation of mitochondrial morphology during spermiogenesis in Phascolosoma esculenta

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Journal of Oceanology and Limnology 2024年第1期42卷 187-200页

作者： Xinming GAO Binbin FENG Chen DU Congcong HOU shan JIN Daojun TANG Junquan ZHU Key Laboratory of Applied Marine Biotechnology by the Ministry of Education and Key Laboratory of Marine Biotechnology of Zhejiang Province School of Marine SciencesNingbo UniversityNingbo 315211China College of Ecology Lishui UniversityLishui 323000China

Mitochondria undergo morphological changes during spermatogenesis in some *** mechanism and role of mitochondrial morphology regulation,however,remain somewhat *** this study,we analyzed the molecular characteristics,expression dynamics and subcellular localization of optic atrophy protein 1(OPA1),a mitochondrial fusion and cristae maintenance-related protein,to reveal the possible regulatory mechanisms underlying mitochondrial morphology in Phascolosoma esculenta *** full-length cDNA of the *** opa1 gene(Pe-opa1)is 3743 bp in length and encodes 975 amino *** Pe-OPA1 protein is highly conservative and includes a transmembrane domain,a GTPase domain,two helical bundle domains,and a lipid-interacting *** and protein expression was higher in the coelomic fluid(a site of spermatid development)of male *** and increased first and then decreased from March to ***,their expression during the breeding stage was significantly higher than during the non-breeding stage,suggesting that Pe-OPA1 is involved in *** *** Pe-OPA1 protein was more abundant in components consisting of many spermatids than in components without,indicating that Pe-OPA1 mainly plays a role in the spermatid in coelomic ***,Pe-OPA1 was mainly detected in the spermatid *** experiments showed that the Pe-OPA1 are constitutively expressed and co-localized with mitochondria during spermiogenesis,suggesting its involvement in *** *** results provide evidence for Pe-OPA1's involvement in the regulation of mitochondrial morphology during spermiogenesis.

关键词： optic atrophy protein 1(OPA1) spermiogenesis Phascolosoma esculenta mitochondrial dynamics spermatid

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