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Investigation of environmental and land use impacts in forested permafrost headwaters of the Selenga-Baikal river system,Mongolia-Effects on discharge,water quality and macroinvertebrate diversity

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International Soil and Water Conservation Research 2021年第4期9卷 605-619页

作者： Martin Pfeiffer Georg Küstner Erdenetsetseg Erdenesukh wolf von tümpling Jürgen Hofmann Department of Biogeography University of BayreuthUniversitätsstraße 3095447 BayreuthGermany Department of Aquatic Ecosystem Analysis and Management(ASAM) Helmholtz Centre for Environmental Research-UFZBrückstraße 3a39114 MagdeburgGermany Department of Ecology National University of MongoliaBaga toiruu 47Ulaanbaatar 210646Mongolia Department of Animal Ecology and tropical Biology BiocenterJulius-Maximilians-Universität WürzburgAm Hubland97074 WürzburgGermany National Dong Hwa University No.1Sec.2Da Hsueh Rd.ShoufengHualien 97401Taiwan Central Laboratory for Water Analytics&Chemometrics Helmholtz Centre for Environmental Research-UFZBrückstrasse 3a39114 MagdeburgGermany Büro für Integrierten Gewässerschutz-BiG Werner-Voß-Damm 54 b12101 BerlinGermany

Headwater streams play a major role for provision of ecosystem services,*** *** investigated a high-altitude headwater catchment of the Kharaa River(including 411st-order rivers)to understand the impact of land cover(especially forest cover),environment and human usage on runoff,chemical water quality and macroinvertebrate fauna in a river basin under discontinuous permafrost conditions in an arid,sparsely populated region of *** verify our hypotheses that different landuses and environmental impacts in permafrost headwaters influence water quality,we investigated 105 sampling sites,37 of them at intermittent stream sections without water *** was positively impacted by land cover types steppe,grassland and forest and negatively by shrubland,forest burnt by wild fires(indicating a reduction of permafrost)and *** quality was affected by altitude,longitude and latitude,shrub growth and water *** diversity of macroinvertebrates was driven by water temperature,iron content of the water,flow velocity,and subbasin size(adjusted R^(2)=0.54).Sample plots clustered in three groups that differed in water chemistry,macroinvertebrate diversity,species composition and *** study confirms that steppes and grasslands have a higher contribution to runoff than forests,forest cover has a positive impact on water quality,and diversity of macroinvertebrates is higher in sites with less nutrients and *** excellent ecological status of the upper reaches of the Kharaa is severely threatened by forest fires and human-induced climate change and urgently needs to be conserved.

关键词： Ecosystem services Ephemeroptera-Plecoptera-trichoptera (EPt)complex GIS-based analysis IWRM-MoMo project Land use land cover(LULC) Natural reference state Runoff Self-purification capacity Stream water chemistry

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Patient age and duration of colonoscopy are predictors for adenoma detection in both proximal and distal colon

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World Journal of Gastroenterology 2015年第2期21卷 525-532页

作者： Peter Klare Stefan Ascher Alexander Hapfelmeier Petra wolf Analena Beitz Roland M Schmid Stefan von Delius Ⅱ.Medizinische Klinik Klinikum rechts der IsarTechnischen Universit?t München81675 MunichGermany Institut für Medizinische Statistik und Epidemiologie Klinikum rechts der IsarTechnische Universit?t München81675 MunichGermany

AIM: to investigate the relation of patient characteristics and procedural parameters to the endoscopic detection rate of colonic adenomas. Further to study,which factors may be capable to predict the localization of adenomatous ***: We used the data base of a prospective randomized colonoscopy study(the Colo Cap trial) to identify patients being diagnosed with colon adenoma. Logistic regression analysis was conducted to reveal predictors for adenoma detection in the entire colon and also with respect to the proximal and distal part. Covariates including age, gender, duration of colonoscopy and comorbidities were defined to determine association between predictors and adenoma ***: Equal numbers of adenomas were detected in the proximal and distal side of the splenic flexure [126(57%) vs 94(43%), P = 0.104]. Simultaneous occurrence of adenomas in both sides of the colon was rare. the appearance of both proximal and distal adenoma was associated with increasing age(P = 0.008 and P = 0.024) and increasing duration of colonoscopy(P tor for adenoma detection in the proximal colon(P = 0.008) but statistical significance was slightly missed with respect to the distal colon(P = 0.089). Alcohol abuse was found to be a predictor for the detection of distal adenoma(P = 0.041). CONCLUSION: Increasing age and longer duration of colonoscopy are factors with a strong impact on adenoma detection both in the proximal and distal colon. Since proximal adenomas occurred in absence of distal adenomas, complete colonoscopy should be performed for screening.

关键词： Adenoma Colorectal carcinoma Distal Colonoscopy Pr

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Fertility and sexual life of men after their forties and in older age

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Asian Journal of Andrology 2001年第1期3卷 1-7页

作者： wolf-Bernhard Schill Department of Dermatoloyg and Andrology Hessian Center of Reprocuctive Medicine Justus Liebig University Giessen Germany

Owing to the demographic development, the aging male will require more consideration in future. In contrast to arapid decline of estradiol during menopause in women, the process of aging in the male is retarded and subject to highindividual variations. Impairment of spermatogenesis is observed as a continuous process occurring over decades. How-ever, only about 50% of men in their eighties show complete loss of fertility. In principle, spermatogenesis may be re-tained well into senescence. Of importance for the individual health condition is the fact that the number of Leydig cellsdeclines with advancing age. thus, altered sex hormone concentrations in aging men result from both functional distur-bances and a gradual reduction in Leydig cells. Furthermore, an impaired feed-back mechanism of the pituitary-gonadalaxis occurs, with disappearance of the circadian testosterone (t) rhythm. LH and FSH levels are increased, and a re-duced bioavailability of sex hormones is observed. Lower total testosterone concentrations in men over 60 years are ac-companied by clinical signs of reduced virility, such as decreased muscle mass and strength as well as reduced sexualhair growth and libido. An age-related decline in androgen secretion and plasma testosterone levels therefore suggeststhe use of androgen supplementation. However, there is a lack of risk-benefit long-term studies. Increased research inthe male is mandatory to meet the requirements of the aging population. this should include the availability of preciseepidemiological data about the frequency of partial androgen deficiency in aging males (PADAM).(Asian J Androl 2001 Mar; 3: 1-7)

关键词： aging spermatogenesis androgens testosterone supplementation

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Expressionism Norbert wolf ; Uta Grosenick (ed.).

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作者： (1949-)wolf Norbert Grosenick Uta.

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Weight changes and patterns of weight measurements in hospitalized burn patients:a contemporary analysis

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Burns & trauma 2018年第4期6卷 262-268页

作者： Denisse Mendez-Romero Audra t Clark Alana Christie Steven E wolf Department of Surgery Division of BurnTraumaand Critical CareUniversity of Texas Southwestern Medical CenterE05514B5323 Harry Hines BlvdDallasTX 75390USA

Background:Severe burn is associated with significant changes in body weight due to resuscitation volumes, fluid shifts, a hypermetabolic state, prolonged bed rest, and caloric intake. Our goal was to quantify and describe trends in weight change in patients with burns of all severities under modern treatment conditions and to identify the time points at which these changes occur. Methods: An institutional review board-approved chart review was conducted of acute burn patients treated at an American Burn Association-verified regional burn center from February 2016 to November 2016. Patients were then divided into three groups based on percent of total burn surface area (%tBSA) burn:1–19%, 20–39%, and≥40%. Weight was expressed as percent change of weight from baseline. Regression analysis was conducted on percent weight changes for each tBSA group. Results:We identified 197 burn patients with a length of stay (LOS) of≥7 days. Of the study cohort, 149 had tBSA burn of 1–19%, 27 had tBSA burn of 20–39%, and 21 had tBSA burn of≥40%. All groups had a majority of White male, non-Hispanic patients with mean ages between 40 and 42 years. Burn patients with>20%tBSA burn had a median increase in weight above baseline of approximately 5 to 8%likely due to resuscitation fluids within the first week of hospitalization. Weight loss below baseline often did not exceed 10% and was more pronounced as LOS increased, mostly in patients with >20% tBSA burn. Whereas patients with 1–19% tBSA burn on average returned to baseline weight at last measurement, patients with 20–39% tBSA and ≥40%tBSA burn continued a decline in weight at 4 weeks (r2=0.57 and 0.55, respectively) on the same trajectory. Conclusions:Burn patients with>20%tBSA burn had an increase in weight above baseline of up to 8%, likely due to resuscitation fluids within the first week of hospitalization. Weight loss below baseline often did not exceed 10%and was more pronounced as LOS increased, mostly in patients with>20%tBS

关键词： Burn Weight Nutrition Metabolism Critical care

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Data-driven prediction of plate velocities and plate deformation of explosive reactive armor

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Defence technology（防务技术） 2022年第12期18卷 2141-2149页

作者： Marvin Becker Andreas Klavzar thomas wolf Melissa Renck Institute of Saint-Louis 5 Rue du Général Cassagnou68330Saint LouisCedexFrance Ecole Centrale de Lille CitéScientifique59651Villeneuve d'AscqCedexFrance

Explosive reactive armor(ERA)is currently being actively developed as a protective system for mobile devices against ballistic threats such as kinetic energy penetrators and shaped-charge *** mobility,the aim is to design a protection system with a minimal amount of required *** efficiency of an ERA is sensitive to the impact position and the timing of the ***,different designs have to be tested for several impact scenarios to identify the best *** analytical models are not predicting the behavior of the ERA accurately enough and experiments,as well as numerical simulations,are too time-consuming,a data-driven model to estimate the displacements and deformation of plates of an ERA system is proposed *** ground truth for the artificial neural network(ANN)is numerical simulation results that are validated with *** ANN approximates the plate positions for different materials,plate sizes,and detonation point positions with sufficient accuracy in *** a future investigation,the results from the model can be used to estimate the interaction of the ERA with a given ***,a measure for the effectiveness of an ERA can be ***,an optimal ERA can be designed and analyzed for any possible impact scenario in negligible time.

关键词： Artificial neural network Explosive reactive armor Finite element simulation Particle simulation Flash X-ray

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Effect of liver regeneration after partial hepatectomy and ischemia-reperfusion on expression of growth factor receptors

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World Journal of Gastroenterology 2006年第24期12卷 3835-3840页

作者： P Baier G wolf-Vorbeck S Hempel Ut Hopt E von Dobschuetz Department of General and Visceral Surgery Albert-Ludwigs-University FreiburgGermany

AIM： to investigate the effects of experimental partial hepatectomy and normothermic ischemia-reperfusion damage on the time course of the expression of four different growth factor receptors in liver regeneration. this is relevant due to the potential therapeutic use of growth factors in stimulating liver regeneration. MEtHODS： For partial hepatectomy （PH） 80% of the liver mass was resected in Sprague Dawley rats. Ischemia and reperfusion （I/R） were induced by occlusion of the portal vein and the hepatic artery for 15 min. the epidermal growth factor receptor, hepatic growth factor receptor, fibroblast growth factor receptor and tumour necrosis factor receptor-1 were analysed by immunohistochemistry up to 72 h after injury. Quantitative Rt-PCR was performed at the time point of minimal receptor expression （24 h）. RESULtS： In immunohistochemistry, EGFR, HGFR, FGFR and tNFR1 showed biphasic kinetics after partial hepatectomy with a peak up to 12 h, a nadir after 24 h and another weak increase up to 72 h. During liver regeneration, after ischemia and reperfusion, the receptor expression was lower; the nadir at 24 h after reperfusion was the same. to evaluate whether this nadir was caused by a lack of mRNA transcription, or due to a posttranslational regulation, Rt-PCR was performed at 24 h and compared to resting liver. In every probe there was specific mRNA for the receptors. EGFR, FGFR and tNFR1 mRNA expression was equal or lower than in resting liver, HGFR expression after I/R was stronger than in the control. CONCLUSION： At least partially due to a post-transcriptional process, there is a nadir in the expression of the analysed receptors 24 h after liver injury. therefore, a therapeutic use of growth factors to stimulate liverregeneration 24 h after the damage might be not successful.

关键词： Partial hepatectomy Liver ischemia Growthfactor receptors

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MtDNA mutations and aging--not a closed case after all?

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Signal transduction and targeted therapy 2021年第3期6卷 555-556页

作者： Alexander M.wolf Laboratory for Morphological and Biomolecular Imaging Faculty of MedicineNippon Medical SchoolTokyoJapan

In a recent paper in Nature Cancer,Smith et *** that mitochondrial DNA(mtDNA)mutations can confer a growth advantage to intestinal tumors by remodeling cell metabolism,particularly toward elevated de novo serine synthesis.1 For the reasons outlined below,in the past decade,the field of mtDNA biology has experienced a relative loss of *** findings of Smith et *** welcome new life into the complex field of mtDNA contributions to aging and cancer.

关键词： al. metabolism elevated

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towards Accurate Bit Error Simulation in Wireless Sensor Networks Including Environmental Influences

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Journal of Computer Science & technology 2020年第4期35卷 809-824页

作者： Sven Pullwitt Robert Hartung Ulf Kulau Lars wolf Institute for Operating Systems and Computer Networks Technische Universitat BraunschweigBraunschweig 38106 Germany

Simulation is a common technique for the evaluation of new approaches and protocols in networked systems and provides many ***,it is also well known that the relevance of the simulation results for real-world applications depends on the various models which are used within the simulation,e.g.,for the characteristics of the radio *** this paper,we introduce the Extended Multipath Raytracing Model,an extension to the ray-tracing radio medium available in Cooja,to improve the modelling of wireless links in simulated Wireless Sensor *** extension allows the simulation of environmental influences onto links on a per node basis,allowing the analysis of various effects observed in experiments in a virtual ***,the packet-based modelling of transmission errors is extended to provide the simulation of bit errors,allowing new usage scenarios,like the simulation of error detection and Forward Error Correction codes in Cooja.

关键词： bit error Contiki Cooja environmental influence simulation wireless sensor network

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Advancement in biochemical assays in andrology

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Asian Journal of Andrology 1999年第1期1卷 45-51页

作者： wolf-BernhardSchill RalfHenkel Center of Dermatology and Andrology Justus Liebig University Giessen GermanyCenter of Dermatology and Andrology Justus Liebig University Giessen Germany

Determination of markers of sperm function, accessory sex gland secretion and silent male genital tractinflammation is of considerable diagnostic value in the evaluation of male infertility. the introduction of biochemicaltests into the analysis of male factor has the advantage that standardized assays with a coefficient of variationcharacteristic of clinical chemistry are performed, in contrast to biological test systems with a large *** parameters may be used in clinical practice to evaluate the sperm fertilizing capacity (acrosin, aniline blue,ROS), to characterize male accessory sex gland secretions (fructose, α-glucosidase, PSA), and to identify men withsilent genital tract inflammation (elastase, C'3 complement component, coeruloplasmin, IgA, IgG, ROS).

关键词： male infertility biological markers spermatozoa male genital diseases sex gland Secretion

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