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World Journal of Gastroenterology 2018年第19期24卷 2130-2136页

作者： maciej Nowacki Dariusz Grzanka wojciech Zegarski Department of Surgical Oncology Ludwik Rydygier's Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Torun Oncology Centre-Prof. Franciszek ?ukaszczyk Memorial Hospital in Bydgoszcz Department of Clinical Pathomorphology Ludwik Rydygier's Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Torun

We report the first application of pressurized intraperitoneal aerosol chemotherapy(PIPAC) as a rescue therapy before palliative D2 gastrectomy combined with liver metastasectomy performed in a 49-yearold woman with peritoneal carcinomatosis who was primarily diagnosed with and underwent surgery for a Krukenberg tumor. The PIPAC procedure was performed with the use of cisplatin at 7.5 mg/m2 and doxorubicin at 1.5 mg/m2 for 30 min at 37 ℃. Eight weeks after the PIPAC procedure, the patient underwent open classic D2 gastrectomy with the creation of a Roux-en-Y anastomosis(RNY) combined with liver metastasectomy. The patient underwent the classic protocol for chemotherapy combined with Xeloda. The patient felt better and returned to her daily activities. multicenter data should be gathered to confirm the usefulness of PIPAC as a rescue or neoadjuvant supportive therapy in a very select group of patients who have been recently qualified to undergo classic chemotherapy or standard oncologic surgical procedures.

关键词： Peritoneal carcinomatosis Pressurized intraperitoneal aerosol chemotherapy Neoadjuvant therapy Gastric cancer Krukenberg tumor

Nanoscale image of the drug/metal mono-layer interaction:Tapping A Fm-IR investigations

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Nano Research 2020年第4期13卷 1020-1028页

作者： Natalia Piergies Alexandre Dazzi Ariane Deniset-Besseau Jeremie mathurin magdalena Ocwieja Czeslawa Paluszkiewicz wojciech m.Kwiatek Institute of Nuclear Physics Polish Academy of SciencesPL-31342 KrakowPoland Laboratoire de Chimie Physique(LCP) CNRS UMR 8000Univ.of Paris-SudUniversite Paris-Saclay91405 OrsayFrance Jerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences Niezapominajek 8PL-30239 KrakowPoland

The application of metal nanoparticles as an efficient drug delivery system is one of the directions of cancer therapy ***,this strategy requires precise information about how the drug interacts with the applied *** this study,atomic force microscopy combined with infrared spectroscopy(AFm-IR)was used for the first time to investigate the erlotinib adsorption structure on two different types of 15 nm metal nanoparticle mono-layers,namely,silver nanoparticle(AgNP)and gold nanoparticle(AuNP)*** the metal nanoparticles are loosely bound samples,only the tapping AFm-IR mode is suitable for the collection of IR maps and spectra for such a *** obtained results indicated the relevance of the AFm-IR technique for characterizing drug interactions with a metal mono-layer *** investigated drug interacts with the AgNPs mainly through phenyl rings and methoxy moieties,while quinazoline,amino,and ethoxy moieties appear to be farther from the *** the AuNPs,the interaction occurs through both the phenyl ring and the quinazoline ***,the aliphatic groups of erlotinib directly participate in this *** novelty of the present work is also related to the use of the tapping AFm-IR mode to study metal NP mono-layers with a drug adsorbed on *** collected IR maps for the most enhanced erlotinib bands show specific areas with very high signal *** connection between these areas and the"hot spots"typical for the surface plasmon resonance phenomenon of metals is considered.

关键词： metal nanoparticle mono-layer drug's adsorption infrared nanospectroscopy atomic force microscopy erlotinib

Experimental and numerical study of pseudo-2D circulating fluidized beds

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Particuology 2016年第6期14卷 48-59页

作者： Adam Klimanek wojciech Adamczyk Sirpa Kallio Pawet Kozolub Gabriel Wecel Institute of Thermal Technology Silesian University of TechnologyKonarskiego 22 44-100 Gliwice Poland Technical Research Centre of Finland Ltd P.O. Box 1000 FI-02044 VTT Finland Amec Foster Wheeler Staszica 31 41-200 Sosnowiec Poland

We present experimental investigations and numerical simulations of a pseudo-2D riser. Experiments were performed for various airflow rates, particle types/diameters, and particle size distributions. Pres- sure distributions along the wall of the riser were measured, Additional measurements from a smaller pseudo-2D riser （Kallio et al., 2009; Shah et al., 2012） were used to analyze horizontal solids volume fraction profiles. The experimental data were compared with simulation results carried out using an Euler-Euler approach, A mesh sensitivity study was conducted for numerical simulations and effects associated with simplifying real 3D geometry to a 2D model were examined. In addition, the effect of using an algebraic equation to represent the granular temperature versus a full partial differential equation also was examined for numerical simulations. Results showed small but significant near-wall sensitivity of the flow variables to mesh size. Substantial differences in mean pressure, solids distribution, and solid velocities were obtained, when 2D and 3D simulation results were compared. Finally, applying the simplified granular temperature equation for turbulent fluidization and for dilute-phase transport can lead to incorrect predictions in models,

关键词： Circulating fluidized bed Euler-Euler approachGas-solid flow Kinetic theory of granular flow Particle size distribution 2D vs 3D

Photoluminescence and energy transfer in transparent glass-ceramics based on GdF3:RE3+（RE=Tb,Eu）nanocrystals

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Journal of Rare Earths 2019年第11期37卷 1137-1144页

作者： Natalia Pawlik Barbara Szpikowska-Sroka Ewa Pietrasik Tomasz Goryczka wojciech A.Pisarski Institute of Chemistry University of Silesia9 Szkolna StreetKatowice 40-007Poland Institute of materials Science University of Silesia75 Putku Piechoty 1A StreetChorzow 41-500Poland

In the present work,the transparent oxyfluoride glass-ceramic samples containing GdF3:RE^3+(RE=Tb,Eu)nanocrystals(nGCs)were fabricated via controlled heat-treatment of precursor xerogels prepared using a sol-gel *** formation of GdF3 nanocrystalline phase from gadolinium(III)trifluoroacetate was verified based on XRD *** average crystal sizes calculated from Scherrer formula were estimated to^10 nm as well as^6 nm for Tb^3+-and Eu^3+-doped samples,*** optical behavior of prepared sol-gel samples was evaluated based on photoluminescence excitation(PLE)and emission spectra(PL)as well as luminescence decay *** samples exhibit the 5D4→7FJ(J=6-3,Tb3+)and the 5D0→7FJ(J=0-4,Eu3+)emission bands recorded within the visible spectral area under excitation at near-UV(393 nm(Eu^3+),351,369,378 nm(Tb^3+))as well as middle-UV illumination(273 nm(Gd3+)).Additionally,based on recorded decay curves,the luminescence lifetimes(τm)for the 5D4(Tb^3+)and the 5D0(Eu3+)excited states were also *** general,recorded luminescence spectra and double-exponential character of decay curves for nGCs indicate a successful migration of Tb^3+and Eu^3+dopant ions from amorphous silicate framework to lowphonon energy GdF3 nanocrystal phase.

关键词： Sol-gel method GdF3 nanocrystals Terbium Europium Rare earths

Experimental and computational study of smoke dynamics from multiple fire sources inside a large-volume building

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Building Simulation 2021年第4期14卷 1147-1161页

作者： Gabriele Vigne wojciech Węgrzyński Alexis Cantizano Pablo Ayala Guillermo Rein Cándido Gutiérrez-montes Fluid Dynamics Division of the Department of mining and mechanical Engineering Universidad de JaénJaénSpain Institute for Research in Technology ICAIUniversidad Pontificia ComillasMadridSpain Building Research Institute(ITB) WarsawPoland Imperial College London LondonUK JVVA Fire&Risk MadridSpain

Fire in large-volume buildings poses separate and distinct challenges from compartmented *** particular,the risk it poses on life safety is mostly due to the smoke it produces,its effects on the evacuation process,and how it can affect the firefighters when they approach the building to fight the fire and rescue the *** is why smoke control in large-volume enclosures is of utter importance for life safety,property protection and business *** research presents an experimental and numerical study of the smoke dynamics from four fire sources(combined heat release rate of 5.2 mW)with different ignition times and under transient ventilation conditions,inside a 20 m high cubic *** measurements in the plume and close to the walls have been recorded using 59 *** data was used in the determination of the smoke layer interface height,with the least-square and the N-Percent *** show that significantly worse conditions are induced by multiple sources than those in a single fire of equal *** results have been obtained using the computational fluid dynamics code FDS(Fire Dynamics Simulator,v6.7.1).The comparison shows that in the far field the temperature predictions are accurate inside the smoke layer(10 m and 15 m)with discrepancies lower than 10%,whereas higher significant discrepancies were observed at the smoke layer interface,i.e.5 m high,with discrepancies up to 20%.Furthermore,a grid analysis has been performed showing that grid resolutions,D*/δ,based on the global HRR of the fire might be sufficient to predict the fire induced conditions far from the *** analysis confirmed the applicability of FDS to the assessment of the smoke dynamics under complex fire conditions away from ***,the present work shows the importance of considering fires with multiple sources due to the faster smoke production compared with single fires.

关键词： experiments simulation fire buildings FDS CFD

Brain GABA and glutamate levels in workers of two ant species （Hymenoptera： Formicidae）： Interspecific differences and effects of queen presence/absence

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Insect Science 2014年第5期21卷 647-658页

作者： Andrzej Wnuk wojciech Kostowski Julita Korczynska Anna Szczuka Beata Symonowicz Przemyslaw Bienkowski Pawel mierzejewski Ewa Joanna Godzinska Laboratory of Ethology Department of Neurophysiology Nencki Institute of Experimental Biology PAS Warsaw Department of Pharmacology and Physiology of the Nervous System Institute of Psychiatry and Neurology Warsaw Poland

Presence of amino acid neurotransmitters gamma-aminobutyric acid （GABA） and glutamate （Glu） in ant brains was reported in very few studies. To learn more about factors influencing GABA and Glu levels in ant brains, we applied high-performance liquid chromatography to measure levels of these compounds in single brains of workers of 2 ant species, myrmica ruginodis （subfamily myrmicinae） and Formica polyctena （subfamily Formicinae） taken from queenright/queenless colony fragments and tested in dyadic aggression tests consisting of an encounter with a nestrnate, an alien conspecific or a small cricket. Brain glutamate levels were higher than those of GABA in both tested species. Brain GABA levels （in μmol/brain） and GABA ： Glu ratio were higher in m. ruginodis （a submissive species） than in E polyctena （a dominant, aggressive species） in spite of smaller brain weight of m. ruginodis. Brain glutamate levels （in μmol/brain） did not differ between the tested species, which implies that glutamate concentration （in μmol/mg of brain tissue） was higher in m. ruginodis. Queen absence was associated with increased worker brain GABA levels in E polyctena, but not in m. ruginodis. No significant effects of opponent type were discovered. As GABA agonists enhance friendly social behavior in rodents, we hypothesize that elevated brain GABA levels of orphaned workers of *** facilitate the adoption of a new queen. This is the first report providing information on GABA and glutamate levels in single ant brains and documenting the effects of queen presence/absence on brain levels of amino acid neurotransmitters in workers of social Hymenoptera.

关键词： Formica polyctena GABA glutamate interspecific differences myrmica ruginodis queen

mn^(5+)-activated Ca_(6)Ba(PO_(4))_(4)O near-infrared phosphor and its application in luminescence thermometry

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Light(Science & Applications) 2022年第10期11卷 2463-2475页

作者： miroslav D.Dramicanin Lkasz marciniak Sanja Kuzman wojciech Piotrowski Zoran Ristic Jovana Perisa Ivana Evans Jelena mitric Vesna Dordevic Nebojsa Romcevic mikhail G.Brik Chong-Geng ma School of Optoelectronic Engineering&CQUPT-BUL Innovation Institute Chongqing University of Posts and TelecommunicationsChongqing 400065PR China Centre of Excellence for Photoconversion Vinca Institute of Nuclear Sciences-National Institute of the Republic of SerbiaUniversity of BelgradeP.O.Box 522Belgrade 11001Serbia Institute of Low Temperature and Structure Research Polish Academy of SciencesOkólna 250-422 WroclawPoland Department of Chemistry Durham UniversityDurham DH13LEUK Institute of Physics University of BelgradePregrevica 11811080 BelgradeSerbia Institute of Physics University of TartuTartu 50411Estonia Department of Theoretical Physics Jan D?ugosz UniversityCzestochowa PL 42200Poland Academy of Romanian Scientists Ilfov Str.No.3050044 BucharestRomania

The near-infrared luminescence of Ca_(6)Ba(PO_(4))_(4)O∶mn^(5+)is demonstrated and *** excited into the broad and strong absorption band that spans the 500-1000 nm spectral range,this phosphor provides an ultranarrow(FWHm=5 nm)emission centered at 1140 nm that originates from a spin-forbidden ^(1)E → ^(3)A_(2) transition with a 37.5%internal quantum efficiency and an excited-state lifetime of about 350 μ*** derived the crystal field and Racah parameters and calculated the appropriate Tanabe-Sugano diagram for this *** found that 1E emission quenches due to the thermally-assisted cross-over with the ^(3)T_(2) state and that the relatively high Debye temperature of 783 K of Ca_(6)Ba(PO_(4))_(4)O facilitates efficient *** Ca_(6)Ba(PO_(4))_(4)O also provides efficient yellow emission of the Eu^(2+)dopant,we calculated and explained its electronic band structure,the partial and total density of states,effective mulliken charges of all ions,elastic constants,Debye temperature,and vibrational ***,we demonstrated the application of phosphor in a luminescence intensity ratio thermometry and obtained a relative sensitivity of 1.92%K^(-1) and a temperature resolution of 0.2 K in the range of physiological temperatures.

关键词： spectra. luminescence excited

BWR ECCS - THERmAL LOADING ANALYSIS OF INTERNALS RELATED TO SPRAY SYSTEm REmOVAL

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BWR ECCS - THERMAL LOADING ANALYSIS OF INTERNALS RELATED TO ...

Analysis of the State of the Fine-Dispersive Precipitations in the Structure of High Strength Steel Weldox 1300 by means of Electron Diffraction

第十三届国际核工程大会

作者： Hernan Tinoco Erik m. Adolfsson wojciech Baltyn Jerzy marcinkiewicz Forsmarks Kraftgrupp AB F-System AB Baltyn Consulting HB Det Norske Veritas Nuclear Technology AB

＜正＞ The end part of the Emergency Core Cooling System （ECCS） of the Boiling Water Reactors （BWRs） at Forsmark Nuclear Power Plant （NPP） is located in the Upper Plenum. It consists of a pipe network equipped with a large number of water injection nozzles. In case of a Loss of Coolant Accident （LOCA）, the ECCS should keep the core covered by water and, at the same time, rapidly cool and decompress the reactor by means of injection

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Analysis of the State of the Fine-Dispersive Precipitations ...

肥胖患者体内金属蛋白酶和脂联素的活性——肥胖手术后造成切口疝的可能因素（英文）

第六届国际低合金高强度钢会议

作者： Ozgowicz wojciech Labisz Krzysztof Division of Constructional and special materials Division of materials Processing Technology Management and Computer Techniques in Materials ScienceInstitute of Engineering Materials and BiomaterialsSilesian University of TechnologyKonarskiego St.18A44-100 GliwicePoland

＜正＞The paper deals with investigations concerning the structure and state of dispersive precipitations of the phases consolidating in the high-strength steel Weldox 1300 after its high temperature thermomechanical treatment. making use of transmission technique of electron microscopy（TEm） mainly the microstructure and morphology of martensite was analysed,as well as the state of dispersive precipitations of carbides and nitrides resulting from microadditives of such alloys as Nb,V,Ti or B,introduced into the *** revealed both a fine lathed and twin structure of the matrix of martensite in the investigated *** means of the method of electron diffraction particles of secondary strengthening phases of the m（C,N） type of a nanocrystalline size could be identified,and also non-metallic oxide inclusions,affecting the mechanism of strengthening of the investigated steel.

关键词： weldox 1300 HSLA steel thermomechanical treatment martensitic steel structural steel

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第1期19卷 65-70页

作者： wojciech SZCZESNY magdalena KULIGOWSKA-PRUSINSKA Stanislaw DABROWIECKI Jakub SZmYTKowski Adrian RESLINSKI maciej SLUPSKI Ludwik Rydygier College of medicine in Bydgoszcz Nicolaus Copernicus University in Torun Bydgoszcz Poland

目的:主要研究病态肥胖患者与正常人血清中金属蛋白酶2(mmP-2)、mmP-9、mmP-13和脂联素的浓度。创新点:建立血清中mmP-2、mmP-9、mmP-13和脂联素的浓度与肥胖和切口疝的关系。方法:参与实验的人员为进行肥胖手术的患者和不进行肥胖手术... 详细信息

目的:主要研究病态肥胖患者与正常人血清中金属蛋白酶2(mmP-2)、mmP-9、mmP-13和脂联素的浓度。创新点:建立血清中mmP-2、mmP-9、mmP-13和脂联素的浓度与肥胖和切口疝的关系。方法:参与实验的人员为进行肥胖手术的患者和不进行肥胖手术的患者,并将他们分为两组:I(体重指数(BmI)≥35 kg/m2,n=40)和I(IBmIm2,n=30),并使用酶联免疫吸附实验测定受试人员体内血清中mmP-2、mmP-9、mmP-13和脂联素的浓度。结论:mmP-2的浓度在肥胖组中更高,且在两组血清中有显著性差异。虽然mmP-9的浓度在肥胖组中更高,但是两组之间没有显著性差异。mmP-13在两组间没有差异。血清中脂联素的浓度在非肥胖组更高,但无显著性差异。因此,血清中mmP-2和mmP-9的浓度在肥胖人群中与更高的切口疝发病率有关。

关键词：金属蛋白酶脂联素肥胖症切口疝