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Hepatobiliary Surgery and Nutrition 2019年第1期8卷 1-9页

作者： Li-Chueh Weng Hsiu-Li Huang Wei-Chen Lee Yu-Hsia Tsai woan-shyuan wang Kang-HuaChen School of Nursing College of MedicineChang Gung UniversityTaoyuanTaiwan Department of General Surgery Transplantation CenterChang Gung Memorial Hospital LinkouTaoyuanTaiwan Department of Long-Term Care College of Health TechnologyNational Taipei University of Nursing and Health ScienceTaipeiTaiwan Department of Cardiovascular Medicine Chang Gung Memorial Hospital LinkouTaoyuanTaiwan Department of Nursing Chang Gung Memorial Hospital LinkouTaoyuanTaiwan

Background:Improving the health-related quality of life(HRQOL)of living liver donors post-donation is an important aspect of care *** the HRQOL of living liver donors prospectively could help improve our understanding of the recovery of HRQOL and help improve the quality of donor *** this study,we examined the HRQOL of living liver donors at pre-donation and at 1-year post-donation and analyzed the effect of pre-and post-donation factors on the donors'physical and mental ***:This was a prospective *** the enrollment period(August 2013 to December 2015),68 living liver donors completed the study questionnaires 5 times:at pre-donation and at 1,3,6,and 12 months *** Medical Outcomes Study Questionnaire Short Form-36,which yields both physical(PCS)and mental(MCS)component summary scores,was used to measure the *** pre-and post-donation factors included donation ambivalence,recipients'physical condition,post-donation complications,and recipients'survival ***:Participants'mean PCS scores were 43.59 and 56.50 at 1 and 12 months after donation,respectively,whereas their mean MCS scores were 46.89 and 46.28,*** mean PCS score was worse at 1 month after donation but improved significantly over time(P0.05).A good PCS score was associated with no surgical complications of donation(coefficient=2.87,P=0.02),whereas a poor MCS score was associated with an education of less than a bachelor's degree(coefficient=?3.60,P=0.004),a higher Model for End-Stage Liver Disease(MELD)score in the recipient(coefficient=?0.13,P=0.03),and recipient death(coefficient=?3.48,P=0.03).Pre-donation ambivalence and sense of coherence were not significant predictors of the PCS or MCS ***:The impact of living liver donation on HRQOL was strongest in the early stages of the post-surgery period for the physical ***-care professionals should carefull

关键词： Ambivalence living-donor liver transplantation(LDLT) long term medical outcome quality of life

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