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骨细胞陷窝-小管系统受损对骨力学适应性重建的影响:基于一种早衰症动物模型的在体实验研究

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骨细胞陷窝-小管系统受损对骨力学适应性重建的影响:基于一种早衰...

文化混搭对群体心理融合的影响:经验开放性的调节作用

第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议

作者：杨海胜 Bettina M.willie 北京工业大学生命科学与生物工程学院生物医学工程系 McGill University Shriners Hospital for Children-Canada

目的骨细胞及其周围高度连通的陷窝-小管系统(LCS)被认为是感应、转导力学信号和调控骨重建的"中枢",但其与骨力学适应性重建的直接联系尚缺乏在体研究的证据。在一种早衰症动物模型中(Gorab),敲除Gorab基因后骨组织中骨细胞数量增多但...

目的骨细胞及其周围高度连通的陷窝-小管系统(LCS)被认为是感应、转导力学信号和调控骨重建的"中枢",但其与骨力学适应性重建的直接联系尚缺乏在体研究的证据。在一种早衰症动物模型中(Gorab),敲除Gorab基因后骨组织中骨细胞数量增多但LCS严重受损,这些变化是否影响骨组织对力学刺激的响应是研究的重点。方法对正常和LCS受损小鼠的后肢左侧胫骨沿轴向施加周期性动载,右侧胫骨作为非加载对照。在加载周期内不同时间点对胫骨进行活体显微CT扫描,利用基于连续显微CT图像的3D骨形态计量学和传统的2D骨

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辽宁师范大学学报（社会科学版） 2020年第4期43卷 50-58页

作者：赵玉芳包燕肖子伦李骐 willie Njoroge 梁芳美西南大学西南民族教育与心理研究中心重庆400715 西南大学心理学部重庆400715 楚雄医药高等专科学校基础医学系云南楚雄675005

心理融合是积极群际关系的表征,是构建和谐社会不可或缺的重要前提。基于群际接触理论,通过两个实验考察了文化混搭对心理融合的影响及其调节因素。实验采用4×2两因素组间设计,先测量被试经验开放性,然后操纵文化混搭,并使用双向社会... 详细信息

心理融合是积极群际关系的表征,是构建和谐社会不可或缺的重要前提。基于群际接触理论,通过两个实验考察了文化混搭对心理融合的影响及其调节因素。实验采用4×2两因素组间设计,先测量被试经验开放性,然后操纵文化混搭,并使用双向社会距离量表(实验一、实验二)和街道距离投射测验(实验二)测量外显和内隐心理融合水平。结果表明,文化混搭不仅能促进外显心理融合也能提升内隐心理融合,经验开放性在其中起调节作用——文化混搭对高经验开放者心理融合有促进作用,对低经验开放者则无显著影响。该结果不仅丰富了心理融合研究,拓展了群际接触理论,也为实践中群体关系管理提供了一定的理论指导。

关键词：心理融合文化混搭经验开放性群际接触理论

How much has the Sun influenced Northern Hemisphere temperature trends?An ongoing debate

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Research in Astronomy and Astrophysics 2021年第6期21卷 131-198页

作者： Ronan Connolly willie Soon Michael Connolly Sallie Baliunas Johan Berglund C.John Butler Rodolfo Gustavo Cionco Ana G.Elias Valery M.Fedorov Hermann Harde Gregory W.Henry Douglas V.Hoyt Ole Humlum David R.Legates Sebastian Liming Nicola Scafetta Jan-Erik Solheim Laszlo Szarka Harry van Loon Victor M.Velasco Herrera Richard C.Willson Hong Yan Weijia Zhang Center for Environmental Research and Earth Science(CERES) SalemMA 01970USA Independent scientists DublinIreland Retired formerly Harvard-Smithsonian Center for AstrophysicsCambridgeMA 02138USA Independent researcher MalmoSweden Retired formerly Armagh ObservatoryCollege HillArmagh BT619DGNorthern IrelandUK Comision de Investigaciones Cientlficas de la provincia de Buenos Aires Argentina Grupo de Estudios Ambientales Universidad Tecnologica NationalColpn 332San Nicolas(2900)Buenos AiresArgentina Laboratorio de Fisica de la Atmosfera Facultad de Ciencias Exactas y TecnologlaUniversidad National de TucumanAv.Independencia 18004000 TucumanArgentina Instituto de Fisica del Noroeste Argentino(Consejo Nacional de Investigaciones Cientficas y Tecnicas-Universidad Nacional de Tucuman) 4000 TucumanArgentina Faculty of Geography LomonosovMoscow State UniversityLeninskie Gory St.1Moscow 119991Russia Helmut-Schmidt-University HamburgGermany Center of Excellence in Information Systems Tennessee State UniversityNashvilleTN 37209 USA Independent scientist Berkeley SpringsWVUSA Emeritus professor in physical Geography Department of GeosciencesUniversity of OsloNorway College of Earth Oceanand the EnvironmentUniversity of DelawareNewark DE 19716-2541USA Institute for Hydrography Geoecology and Climate SciencesHauptstra/3e 476315 AgeriSwitzerland Department of Earth Sciences Environment and GeoresourcesUniversity of Naples Federico nComplesso Universitario di Monte S.Angelovia Cinthia2180126 NaplesItaly Retired formerly Department of Physics and TechnologyUiT The Arctic University of Norway9037 TromspNorway ELKH Institute of Earth physics and Space Science 9400 SopronCsatkai utca 6-8Hungary Retired formerly National Center for Atmospheric ResearchBoulderColoradoUSA Instituto de Geofisica Universidad Nacional Autonoma de MexicoCiudad UniversitariaCoyoacan04510Mexico D.F.Mexico Active Cavity Radiometer Irradiance Monitor(ACRIM) CoronadoCA 92118USA State Key Laboratory of Loe

In order to evaluate how much Total Solar Irradiance(TSI)has influenced Northern Hemisphere surface air temperature trends,it is important to have reliable estimates of both *** different estimates of the changes in TSI since at least the 19th century were compiled from the *** of these estimates are"low variability"and half are"high variability".Meanwhile,five largely-independent methods for estimating Northern Hemisphere temperature trends were evaluated using:1)only rural weather stations;2)all available stations whether urban or rural(the standard approach);3)only sea surface temperatures;4)tree-ring widths as temperature proxies;5)glacier length records as temperature *** standard estimates which use urban as well as rural stations were somewhat anomalous as they implied a much greater warming in recent decades than the other estimates,suggesting that urbanization bias might still be a problem in current global temperature datasets-despite the conclusions of some earlier ***,all five estimates confirm that it is currently warmer than the late 19th century,i.e.,there has been some"global warming"since the 19th *** each of the five estimates of Northern Hemisphere temperatures,the contribution from direct solar forcing for all sixteen estimates of TSI was evaluated using simple linear least-squares *** role of human activity on recent warming was then calculated by fitting the residuals to the UN IpCC’s recommended"anthropogenic forcings"time *** all five Northern Hemisphere temperature series,different TSI estimates suggest everything from no role for the Sun in recent decades(implying that recent global warming is mostly human-caused)to most of the recent global warming being due to changes in solar activity(that is,that recent global warming is mostly natural).It appears that previous studies(including the most recent IpCC reports)which had prematurely concluded the former,had done so be

关键词： Sun:activity (Sun:)solar terrestrial relations (Sun:)sunspots Sun:faculae,plages

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“手风琴”牵张成骨的实验和模拟研究

医用生物力学 2021年第S1期36卷 19-19页

作者：杨海胜 Bettina M.willie 北京工业大学生物医学工程系生物力学实验室 McGill University Shriners Hospital for ChildrenCanada

目的牵张成骨术(DO)通过牵张器对骨骼施加稳定和缓慢的牵张力,刺激截骨间隙内新骨形成和矿化,以实现延长骨骼的目的。但其最主要的临床问题是巩固期新骨形成缓慢,导致治疗周期漫长。临床报道,在巩固期施加交替牵-模式的"手风琴"技术(AT... 详细信息

目的牵张成骨术(DO)通过牵张器对骨骼施加稳定和缓慢的牵张力,刺激截骨间隙内新骨形成和矿化,以实现延长骨骼的目的。但其最主要的临床问题是巩固期新骨形成缓慢,导致治疗周期漫长。临床报道,在巩固期施加交替牵-模式的"手风琴"技术(AT)可有效治疗一些骨再生不良或矿化缓慢的情况。然而,尚不清楚AT的最佳应用时机。采用动物实验与数值模拟相结合的方法,探究在巩固期不同时机行使AT对DO骨再生的影响。方法对小鼠股骨干进行截骨术和为期10 d的牵张。

关键词：新骨形成牵张成骨巩固期应用时机截骨术骨间隙临床报道不同时机

A Life Cycle Assessment Based Evaluation of a Coupled Wastewater Treatment and Biofuel production paradigm

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Journal of Environmental protection 2013年第9期4卷 1018-1033页

作者： Monica C. Rothermel Amy E. Landis William J. Barr Kullapa Soratana Kayla M. Reddington Matthew K. Weschler Grace Witter willie F. Harper De- partment of Systems Engineering and Management Air Force Institute of Technology WPAFB USA Department of Civil and Environmental Engineering University of Pittsburgh Pittsburgh USA School of Sustainable Engineering and the Built Environment Global Institute of Sustainability Arizona State University Engineering G-Wing Tempe USA

A laboratory experiment was performed to determine the feasibility of coupling a conventional wastewater treatment system with an algal photobioreactor (pBR) for the removal of nutrients from wastewater and production of renewable resources. An activated sludge batch reactor was set up in series with an algal pBR to feed synthetic wastewater to Chlorella vulgaris. The nutrient concentration in the water as well as lipid content, carbohydrate content, and growth rate of the algal biomass were tested over 10 cycles to determine the capabilities of the coupled system. The study revealed complete nutrient removal in some cycles, with the average final nutrient content of 2 mg-p/L and 3 mg-N/L in effluent of the pBR. The algae biomass contained 24% ± 3% lipids and 26% ± 7% carbohydrates by dry weight. A life cycle assessment revealed the highest energy demand occurred during harvesting of the algal mixture through centrifugation or filtration, but the highest global warming and eutrophication impacts were due to CO2 use and pBR construction material production. It is feasible for the system to treat wastewater while generating renewable resources, but the system must be optimized to reduce life cycle environmental impacts and result in a net energy gain before large-scale implementation is possible.

关键词： Wastewater Biofuels Life Cycle Assessment Nitrogen Carbohydrate

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方差损失准则下的自由网分析

浙江测绘 1990年第3期 44-47页

作者： willie Tan[澳大利亚] 陆晓鸣（编译）姚如松（校）

在应用极小控制的地方，尤其在变形测量中，常常要用自由网平差。本文提供了应用方差损失准则时自由网分析的另一个观点，并与实施极小约束时消去设计矩阵适当列的传统方法作了比较。文章表明这两种方法都是广义自由网平差的特例。

关键词：自由网平差失准方差变形测量传统方法设计矩阵极小应用

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星际总动员

疯狂英语（初中天地） 2008年第7期 10-10页

作者： willie Wrestler 洪馥芝

曾出品《汽车总动员》和《料理鼠王》等著名动画片的皮克斯公司今年又会给我们带来什么呢?公元2700年,地球堆满垃圾,人类被迫移居太空,并派了一批机器人WALL·E(Waste Allocation Load Lifter Earth-Class的缩写,即"地球废品分装员")在... 详细信息

曾出品《汽车总动员》和《料理鼠王》等著名动画片的皮克斯公司今年又会给我们带来什么呢?公元2700年,地球堆满垃圾,人类被迫移居太空,并派了一批机器人WALL·E(Waste Allocation Load Lifter Earth-Class的缩写,即"地球废品分装员")在地球清理垃圾,等待某天重返地球。然而这些机器人不适应地球的环境,陆续坏掉,最后只剩下一个还在日复一日地按照程序收拾废品。对于他来说,捡垃圾就是他存在的意义。但很快他就会发现其存在的真正意义……

关键词：机器人

Quality Control at Nomophobia and Dependency to Technological

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International Journal of Mental Health promotion 2023年第8期25卷 891-901页

作者： pearlyne willie Wong Huay Woon You pusat GENIUS@pintar Negara Universiti Kebangsaan MalaysiaSelangor43600Malaysia

This study aims to investigate the phenomenon of technological gadget usage among pre-university students,which include the time spent using them,as well as their purpose and inﬂuence.A descriptive research design was adopted in this study.131 pre-university students were randomly selected to answer a structured *** were informed two weeks earlier to keep track on their time spent on technological devices,before answering the *** showed that 99.2%of the respondents owned at least two technological gadgets,and all respondents own a *** main two gadgets that respondents spend at least 4 h a day on are smartphones(65.6%)and computers/laptops(21.4%).This indicates that smartphones are commonly used and owned among the *** majority of the respondents are moderately nomophobia and moderately dependent on smartphones(70.2%and 66.4%,respectively).Correlation analysis demonstrates that the total time spent on gadgets in a day has a signiﬁcant positive correlation with gadget dependency and total number of gadgets ***,logistic regression was conducted to estimate the probability of nomophobia and dependency using total time spent and total number of technological *** theﬁndings,it was demonstrated that when the total time spent on using technological gadgets increasing,there is greater probability that the respondents develop nomophobia and *** indicates that nomophobia and dependency to technological gadgets can be used to predict lifestyle proﬁ*** use of technological gadgets can bring both beneﬁt and harm to its *** light of this,user has to remain rational in order to derive maximum beneﬁt from it.

关键词： Nomophobia dependency technological gadgets pre-university students quality control

立体定向激光消融术治疗脑海绵状血管瘤所致癫痫的安全性和有效性

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癫痫杂志 2020年第4期6卷 366-376页

作者： Jon T willie James G Malcolm Matthew A Stern 张乐(译) 慕洁(审) Robert E Gross 不详

核磁共振(MR)热成像引导激光间隙热疗或立体定向激光消融术(Stereotactic laser ablation,SLA是开颅手术治疗脑海绵状血管瘤(Cerebral cavernous malformations,CCMs)所致局灶性癫痫的微创替代术。此研究检测了SLA治疗致痫性CCMs的安全... 详细信息

核磁共振(MR)热成像引导激光间隙热疗或立体定向激光消融术(Stereotactic laser ablation,SLA是开颅手术治疗脑海绵状血管瘤(Cerebral cavernous malformations,CCMs)所致局灶性癫痫的微创替代术。此研究检测了SLA治疗致痫性CCMs的安全性和有效性,回顾性分析连续19例伴有CCM的局部发作的患者。每例患者均接受CCMs和邻近皮质的SLA,继而进行标准的临床和影像学随访。除1例患者外,所有患者均患有慢性难治性癫痫(中位病程8年,年龄范围0.5~52岁)。病变位于颞叶(13例)、额叶(5例)和顶叶(1例)。CCMs在测温过程中会诱发磁化率伪影,但病灶周围皮层易于观察。在接受12个月以上随访的17例患者中,有14例(82%)达到了Engel I级,其中10例(59%)为Engel IA级。2例患者仅接受SLA后未达到无发作,在进一步行颅内电极引导下开放性切除术后达到了无发作。延迟的术后影像学检查证实了CCMs缩小(中位数减少83%)和周围皮质的消融。开放手术后对一个先前消融的CCM组织病理学检查证实闭塞。SLA未引起可检测的出血。两种症状性神经功能缺损(视觉和运动障碍)是可预见的,且均非永久残疾。在连续的回顾性研究中,MR热成像指导的SLA是致痫性CCMs开放手术治疗的有效替代方法。该方法无出血并发症,且临床上明显的神经功能缺损是可预见的。若有需要,SLA对后续的开放手术无任何障碍。

关键词：脑海绵状血管瘤激光间隙热疗病灶性癫痫磁共振测温癫痫发作立体定向激光消融术