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Exertional calf pain at kilometer five - Finding the cause

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Sports Medicine and Health Science 2024年第1期6卷 89-93页

作者： Samuel A.Renier Angela M.Voight Emilee J.Trost william O.Roberts St.John's Hospital Family Medicine Residency Department of Family Medicine and Community HealthUniversity of Minnesota Medical SchoolMinneapolisMNUSA Summit Orthopedics Woodbury Clinic2090 Woodwinds Dr.WoodburyMN55125USA Minnesota Distance Elite 4007Forest RdMinneapolisMN55416USA Department of Family Medicine and Community Health University of Minnesota Medical School516 Delaware St.SE6-240 Phillips-Wangensteen BuildingMinneapolisMN55455USA

A 23-year-old professional distance runner with several years of exertional calf pain was diagnosed with a unique mixed type III and functional popliteal artery entrapment syndrome(PAES).Surgical reduction of the obstructing tissue allowed her to return to professional *** case highlights the importance of including PAES in the differential for chronic intermittent lower extremity claudication and outlines the work-up required to diagnose this vascular obstruction in younger athletes.

关键词： Claudication Lower leg pain Vascular imaging PAES FPAES Popliteal entrapment

Tropical Cyclone Ocean Winds and Structure Parameters Retrieved from Cross-Polarized SAR Measurements

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Journal of Meteorological Research 2024年第5期 937-953页

作者： He FANG Gaofeng FAN william PERRIE Zhengquan LI Chi ZHANG Guosheng ZHANG Jingsong YANG Zhejiang Climate Centre Key Laboratory of Meteorological Disaster Ministry of Education (KLME)/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters (CIC-FEMD)Nanjing University of Information Science&Technology State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological Administration Fisheries and Oceans Canada Bedford Institute of Oceanography Zhejiang Meteorological Information Network Centre State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural Resources

Spaceborne synthetic aperture radar（SAR） can provide unique capabilities to measure ocean surface winds under tropical cyclones（TCs）, on synoptic scales, and at a very high spatial resolution. In this paper, we first discuss the accuracy and reliability of SAR-retrieved TC marine winds. The results show that wind retrievals from SAR images are in good agreement with Stepped Frequency Microwave Radiometer（SFMR） measurements, with root-mean-square error（RMSE） and correlation coefficient（CC） of 3.52 m s-1and 0.91, respectively. Based on the marine winds retrieved from SAR images, a relatively simple method is applied to extract the storm intensity（maximum wind speed）and wind radii（R34, R50, and R64） from 234 cross-polarized SAR images, in the Northwest Pacific Ocean from2015 to 2023. The SAR-retrieved TC wind radii and intensities are compared with the best-track reports, with RMSEs for R34, R50, and R64 being 48.32, 41.88, and 38.51 km, and CCs being 0.87, 0.83, and 0.65, *** terms of TC intensity, the RMSE and bias between SAR estimates and best-track data are 7.32 and 0.38 m s-1,respectively. For TC Surigae（2023）, we found that employing a combination of multiplatform SARs, acquired within a short time interval, has the potential to simultaneously measure the intensity and wind structure parameters. In addition, for a storm with a long life cycle, the multitemporal synergistic SARs can be used to investigate fine-scale features of the TC ocean winds, as well as the evolution of TC surface wind intensities and wind structures.

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Randomised study of bailout intracranial angioplasty following thrombectomy for acute large vessel occlusion(ANGEL-REBOOT):protocol of a multicentre randomised controlled trial

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Stroke & Vascular Neurology 2024年第2期9卷 181-188页

作者： Feng Gao Xu Tong Baixue Jia Ming Yang Yuesong Pan Zeguang Ren william Scott Burgin Liping Liu Xingquan Zhao Yilong Wang Yongjun Wang Zhongrong Miao Interventional Neuroradiology Department of NeurologyBeijing Tiantan HospitalBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalBeijingChina Department of Neurosurgery University of South FloridaTampaFloridaUSA Department of Neurology Morsani College of MedicineUniversity of South FloridaTampaFloridaUSA Comprehensive Stroke Center Tampa General HospitalTampaFloridaUSA Department of Neurology Beijing Tiantan HospitalBeijingChina

Rationale Unsuccessful thrombectomy of acute large vessel occlusions(LVOs)has been associated with unfavourable *** randomised controlled trials(RCTs)have reported a failure rate of 12%–41%for thrombectomy *** factors contribute to failed thrombectomy,including technical difficulties in accessing the occlusion,unsuccessful thrombus retrieval,thrombotic reocclusion and pre-existing intracranial atherosclerotic *** some studies have explored balloon dilation or permanent stenting as rescue intracranial angioplasty for failed thrombectomy in individual cases,there is currently no evidence from RCTs on this specific *** To evaluate the potential superiority of bailout angioplasty over standard treatment in cases of unsuccessful recanalisation(eTICI 0 to 2a)or residual severe stenosis(>70%)after thrombectomy in acute LVO patients within 24 hours of stroke *** This study is a multicentre,prospective,randomised,controlled clinical trial designed by *** compares bailout angioplasty with standard therapy and follows an open-label treatment approach while maintaining a blinded outcome assessment(PROBE design).Our objective is to allocate 348 patients in a 1:1 ratio to either receive bailout angioplasty as an intervention or standard therapy as a control,following unsuccessful *** The main measure of interest is the modified Rankin Scale(mRS)Score,which will be assessed in a blinded manner at 90(±14)days following *** primary effect size will be determined using ordered logistic regression to calculate the common OR,representing the shift on the six-category mRS Scale at the 90-day ***,the safety outcomes will be evaluated,including symptomatic intracranial haemorrhage within 18–36hours,severe procedure-related complications and mortality within 90(±14)days,among *** The ANGEL-REBOOT study aims to generate substantial evidence regarding the efficacy

关键词： angioplasty throm intracranial

Manipulation of photosensory and circadian signaling restricts phenotypic plasticity in response to changing environmental conditions in Arabidopsis

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Molecular Plant 2024年第9期17卷 1458-1471页

作者： Martin william Battle Scott Fraser Ewing Cathryn Dickson Joseph Obaje Kristen N.Edgeworth Rebecca Bindbeutel Rea LAntoniou-Kourounioti Dmitri A.Nusinow Matthew Alan Jones Plant Science Group School of Molecular BiosciencesUniversity of GlasgowGlasgow G128QQUK Danforth Plant Science Center St.LouisMO 63132USA Department of Biological and Biomedical Sciences Washington University in St.LouisSt.LouisMO 63130USA Present address:School of Biological and Environmental Sciences Liverpool John Moores UniversityLiverpool L22QPUK

Plants exploit phenotypic plasticity to adapt their growth and development to prevailing environmental *** of light and temperature signals is aided by the circadian system,which provides a temporal *** plasticity provides a selective and competitive advantage in nature but is obstructive during large-scale,intensive agricultural practices since economically important traits(including vegetative growth and flowering time)can vary widely depending on local environmental *** prevents accurate prediction of harvesting times and produces a variable *** this study,we sought to restrict phenotypic plasticity and circadian regulation by manipulating signaling systems that govern plants'responses to environmental *** modeling of plant growth and develop-ment predicted reduced plant responses to changing environments when circadian and light signaling pathways were *** tested this prediction by utilizing a constitutively active allele of the plant photoreceptor phytochrome B,along with disruption of the circadian systemvia mutation of *** found that these manipulations produced plants that are less responsive to light and temper-ature cues and thus fail to anticipate *** engineered plants have uniform vegetative growth and flowering time,demonstrating how phenotypic plasticity can be limited while maintaining plant *** has significant implications for future agriculture in both open fields and controlled environments.

关键词： circadian developmental plasticity phenotypic plasticity external coincidence light temperature

Breakdown of a Commonly Practiced Technique in Quantum Mechanics

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Journal of Applied Mathematics and Physics 2024年第5期12卷 1919-1929页

作者： Pirooz Mohazzabi william D. Parker Peter Kveton Department of Mathematics and Physics University of Wisconsin-Parkside Kenosha USA

The dynamically shifted oscillator is investigated quantum mechanically, both analytically and numerically. It is shown that the commonly used method of solving the Schrödinger equation using power series results in i... 详细信息

关键词： Dynamic Shift Oscillator Quantum Schrödinger Solution

Drought Tolerance and Recovery of the Sedge Carex planostachys (Cyperaceae) from Central Texas Woodlands

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American Journal of Plant Sciences 2024年第9期15卷 746-765页

作者： E. Rob Wayne Oscar william Van Auken Natural Sciences Department St. Philips College San Antonio USA Department of Integrative Biology The University of Texas at San Antonio San Antonio USA

Carex planostachys Kunze (Cyperaceae, Cedar sedge) is an herbaceous species in a genus commonly inhabiting mesic or hydric habitats. Carex planostachys is found in arid and semi-arid Juniperus woodlands. Arid conditions impose survival challenges to plants in dry areas. Some plants have plasticity responses to soil water content and continued normal though reduced functions through droughts, but most herbaceous plants do not survive. Limited previous studies have suggested C. planostachys is tolerant of drought. Physiological responses of C. planostachys from Juniperus woodlands was examined is this study to determine how long plants could survive without water and if they are capable of recovery from very negative water potentials beyond what is considered the permanent wilting point for most herbaceous plants. Plants were placed in pots in partial shade in this experiment. Water loss from the soil with plants was an inverse 2nd order polynomial function with soil water decreasing from 32% to 8% by day 28 of the study. Leaf water potential was also an inverse 2nd order polynomial function but did not decline significantly until 14 days without watering. Leaf water potential was −10.0 MPa after 35 days without watering. Non-watered plants Anet, (photosynthetic rate) was significantly lower compared to the water treatment by day 21 as was stomatal conductance and transpiration. When non-watered plants were watered after 21, 28 or 35 days, full recovery of physiological responses occurred within 7 days. The length of time that C. planostachys was able to withstand drought was greater than the annual trends in lack of precipitation during springtime in this area. Carex planostachys can photosynthesize at water stress between −8 and −10 MPa. Carex planostachys drought and shade tolerance enables it to occupy an understory niche devoid of other herbaceous plants.

关键词： CO2 Uptake Conductance Gas Exchange Photosynthesis Respiration Transpiration Water Stress Water Potential.

Polyethylene glycol fusion repair of severed sciatic nerves accelerates recovery of nociceptive sensory perceptions in male and female rats of different strains

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Neural Regeneration Research 2025年第9期20卷 2667-2681页

作者： Liwen Zhou Karthik Venkudusamy Emily A.Hibbard Yessenia Montoya Alexa Olivarez Cathy Z.Yang Adelaide Leung Varun Gokhale Guhan Periyasamy Zeal Pathak dale R.Sengelaub George D.Bittner Department of Neuroscience University of TexasAustinTXUSA Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Molecular Biosciences University of TexasAustinTXUSA

Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary *** preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion *** the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis *** nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the *** von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve *** withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not *** thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated *** sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the ***,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative

关键词： autophagia axotomy collateral sprouting neuropathic pain peripheral nerve repair polyethylene glycol fusion(PEG-fusion) saphenous nerve sensory neurons sex and strain Wallerian degeneration

Seasonal variation and host sex affect bat–bat fly interaction networks in the Amazonian savannahs

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Integrative Zoology 2024年第3期19卷 400-416页

作者： Paulo MEJIA Gustavo Lima URBIETA Bruna da Silva XAVIER IsaíJorge de CASTRO JoséJúlio DE TOLEDO Gustavo GRACIOLLI Lucio AndréVIANA DIAS william Douglas CARVALHO Programa de Pós-Graduação em Biodiversidade Tropical Universidade Federal do Amapá(UNIFAP)MacapáAPBrazil Programa de Pós-Graduação em Ecologia Instituto de BiologiaCentro de Ciências da SaúdeUniversidade Federal do Rio de Janeiro(UFRJ)Rio de JaneiroRJBrazil Laboratório de Mamíferos Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá(IEPA)MacapáAPBrazil Programa de Pós-Graduação em Biologia Animal Laboratório de SistemáticaEcologia e Evolução(LSEE)Instituto de BiociênciasUniversidade Federal de Mato Grosso do Sul(UFMS)Campo GrandeMTBrazil Terrestrial Ecology Group(TEG-UAM) Departamento de EcologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridMadridSpain

Bats are the second-most diverse group of mammals in the world,and bat flies are their main ***,significant knowledge gaps remain regarding these antagonistic interactions,especially since diverse factors such as seasonality and host sex can affect their network ***,we explore the influence of such factors by comparing species richness and composition of bat flies on host bats,as well as specialization and modularity of bat–bat fly interaction networks between seasons and adult host *** captured bats and collected their ectoparasitic flies at 10 sampling sites in the savannahs of AmapáState,northeastern region of the Brazilian *** female bats being more parasitized and recording greater bat fly species richness in the wet season,neither relationship was statistically *** pooled network could be divided into 15 compartments with 54 links,and all subnetworks comprised>12 *** total number of links ranged from 27 to 48(for the dry and wet seasons,respectively),and female and male subnetworks had 44 and 41 links,*** values were very low for the pooled network and for all *** results revealed higher bat fly species richness and abundance in the wet season,whereas specialization and modularity were higher in the dry ***,the subnetwork for female bats displayed higher specialization and modularity than the male ***,both seasonality and host sex contribute in different ways to bat–bat fly network *** studies should consider these factors when evaluating bat–bat fly interaction networks.

关键词： Amapá Amazon biome bat flies bats interaction networks

Ion migration in 3D metal halide perovskite field effect transistors

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Electron 2024年第2期2卷 85-97页

作者： Jinghai Li Yanyan Gong william W.Yu School of Chemistry and Chemical Engineering Shandong UniversityJinanChina Shandong Provincial Key Laboratory for Science of Material Creation and Energy Conversion Science Center for Material Creation and Energy ConversionInstitute of Frontier and Interdisciplinary ScienceShandong UniversityQingdaoChina State Key Laboratory of Biobased Material and Green Papermaking Qilu University of Technology(Shandong Academy of Sciences)JinanChina

3D perovskite materials are advancing rapidly in the field of photovoltaics and light-emitting diodes,but the development in field effect transistors(FETs)is limited due to their intrinsic ion *** migration in perovskite FETs can screen the electric field of the gate and affect its modulation,as well as influence the charge carriers transport,leading to non-ideal device characteristics and lower device ***,we provide a concise review that explains the mechanism of ion migration,summarizes the strategies for suppressing ion migration,and concludes with a discussion of the future prospects for 3D perovskite FETs.

关键词： 3D metal halide perovskite field effect transistors ion migration