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基于UDEC的岩脉侵入角度对隧道安全影响分析

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山西建筑 2025年第1期51卷 164-167页

作者：王毅李乔四川省交通建设集团有限责任公司四川成都610000 江苏丰县221700

为探究岩脉侵入角度对隧道开挖的影响,文章以泸石高速石棉隧道开挖时地层遭遇不同角度岩脉侵入为工程背景,通过UDEC离散元计算,总结岩脉侵入角度对隧道开挖的影响,给出有效处理措施,并得出以下结论:岩脉和被侵入岩体界面易发生塑性滑移... 详细信息

为探究岩脉侵入角度对隧道开挖的影响,文章以泸石高速石棉隧道开挖时地层遭遇不同角度岩脉侵入为工程背景,通过UDEC离散元计算,总结岩脉侵入角度对隧道开挖的影响,给出有效处理措施,并得出以下结论:岩脉和被侵入岩体界面易发生塑性滑移,隧道开挖后岩脉区围岩变形最大,且岩脉区围岩有开裂、滑移和隆起现象,围岩变形随角度的减小而减小。边墙与仰拱连接处轴力、剪力、弯矩均最大,安全系数最小,三种工况均在0.3左右。衬砌轴力、剪力的最大值随角度减小而增大,弯矩受角度的影响较小。岩脉区域的安全系数在向着岩脉倾斜方向更小。岩脉侵入区域隧道开挖应采用岩脉区域局部注浆、封闭仰拱、增大衬砌厚度三种方法来加固围岩和提高衬砌承载能力。

关键词：隧道工程侵入岩脉 UDEC离散元处置措施

Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses

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Traditional Medicine Research 2025年第2期10卷 55-64页

作者： Jin-Fang Wu yi-Sheng Chen Yu-Chun Xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key Laboratory of Toxicant and Drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central Laboratory Jiangsu Province Geriatric HospitalNanjing 210024China

Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditional and exercise ***:Four samples were analyzed:older control(OC),older exercise(OE),younger control(YC),and younger exercise(YE).Single-cell RNA sequencing was used to distinguish cellular subtypes through their biomarker *** visualization included violin and t-SNE plots to illustrate biomarker expression across cell clusters such as oligodendrocytes,microglia,and ***,BV2 cells were exposed to amyloid-beta fragments to simulate Alzheimer’s disease,assessing the impact of exercise-induced cellular ***:Distinct cellular subtypes were identified:oligodendrocytes(MBP,St18),microglia(Dock8),and astrocytes(Aqp4,Gpc5).Sample OE was predominantly oligodendrocytes,while YE had more astrocytes,inhibitory neurons,and Canal-Retzius *** showed a significant presence of Olfm3+ganglion ***1 gene knockout revealed changes in SMAD family gene expression,which regulate *** stress levels were also ***:This profiling enhances our understanding of brain cellular functions and interactions,potentially informing targeted therapies in neurological *** may influence brain cell immune responses and cell death pathways by regulating specific gene expressions,offering new insights for treating neuroinflammation and degeneration.

关键词： single-cell transcriptomics brain tissue cellular subtypes biomarker expression neuronal diversity

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利伐沙班在犬和猫临床应用的研究进展

动物医学进展 2025年第1期46卷 97-102页

作者：王炜江蓝路心怡付诗懿刘亦婷韦力煣俞峰刘波中国农业大学动物医学院北京100193 中国农业大学教学动物医院北京100193

血栓栓塞是犬、猫临床上多种疾病的并发症,可累及动脉或静脉,预后较差。目前兽医临床防治血栓栓塞可用的抗血栓药物种类有限,影响临床诊疗水平,引入新药具有实际意义。利伐沙班是一种新型非维生素K拮抗剂类口服抗凝药物,研究证明其能够... 详细信息

血栓栓塞是犬、猫临床上多种疾病的并发症,可累及动脉或静脉,预后较差。目前兽医临床防治血栓栓塞可用的抗血栓药物种类有限,影响临床诊疗水平,引入新药具有实际意义。利伐沙班是一种新型非维生素K拮抗剂类口服抗凝药物,研究证明其能够特异性抑制活性凝血因子X从而抑制血栓形成。近年来人医领域对利伐沙班的相关临床研究逐渐丰富,涉及单用利伐沙班或使用双通路抑制疗法防治不同类型的动、静脉血栓栓塞,可为其应用于兽医临床提供据。犬、猫临床使用利伐沙班的研究正相继开展,论文就犬、猫血栓栓塞疾病发病情况、防治现状,利伐沙班的药理学特性及其在人医、兽医领域的临床试验研究进展进行综述,以期为兽医临床上利伐沙班的进一步研究提供参考。

关键词：新型口服抗凝药利伐沙班血栓栓塞犬猫

Incompressible Limit of the Compressible Q-tensor System of Liquid Crystals

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Acta Mathematicae Applicatae Sinica 2023年第1期39卷 179-201页

作者： yi-xuan wang University of Pittsburgh PA 15260USA

We study the connection between the compressible Navier-Stokes equations coupled by the Qtensor equation for liquid crystals with the incompressible system in the periodic case, when the Mach number is low. To be more specific, the convergence of the weak solutions of the compressible nematic liquid crystal model to the incompressible one is proved as the Mach number approaches zero, and we also obtain the similar results in the stochastic setting when the equations are driven by a stochastic force. Our approach is based on the uniform estimates of the weak solutions and the martingale solutions, then we justify the limits using various compactness criteria.

关键词： compressible liquid crystal system Q-tensor weak solutions martingale solution stochastic compactness Mach number incompressible limit

A new procedure for investigating three-dimensional stress fields in a thin plate with a through-the-thickness crack

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Science China(Physics,Mechanics & Astronomy) 2018年第6期61卷 50-61页

作者： Dake yi TzuChiang wang College of Mechanics and Materials Hohai University The State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences

In the paper, a new procedure is proposed to investigate three-dimensional fracture problems of a thin elastic plate with a long through-the-thickness crack under remote uniform tensile loading. The new procedure includes a new analytical method and high accurate finite element simulations. In the part of theoretical analysis, three-dimensional Maxwell stress functions are employed in order to derive three-dimensional crack tip fields. Based on the theoretical analysis, an equation which can describe the relationship among the three-dimensional J-integral J(z), the stress intensity factor K(z) and the tri-axial stress constraint level Tz(z) is derived first. In the part of finite element simulations, a fine mesh including 153360 elements is constructed to compute the stress field near the crack front, J(z) and Tz(z). Numerical results show that in the plane very close to the free surface, the K field solution is still valid for in-plane stresses. Comparison with the numerical results shows that the analytical results are valid.

关键词： three-dimensional fracture analysis out-of-plane constraint three-dimensional J-integral

FPGA based unified architecture for public key and private key cryptosystems

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Frontiers of Computer Science 2013年第3期7卷 307-316页

作者： yi wang Renfa LI Embedded Systems and Networking Laboratory Hunan Province Key Laboratory of Network and Information Security Hunan University Changsha 410082 China Department of Electrical and Computer Engineering National University of Singapore Singapore 117576 Singapore

Recently, security in embedded system arises attentions because of modern electronic devices need cau- tiously either exchange or communicate with the sensitive data. Although security is classical research topic in world- wide communication, the researchers still face the problems of how to deal with these resource constraint devices and en- hance the features of assurance and certification. Therefore, some computations of cryptographic algorithms are built on hardware platforms, such as field program gate arrays （FPGAs）. The commonly used cryptographic algorithms for digital signature algorithm （DSA） are rivest-shamir-adleman （RSA） and elliptic curve cryptosystems （ECC） which based on the presumed difficulty of factoring large integers and the algebraic structure of elliptic curves over finite fields. Usu- ally, RSA is computed over GF（p）, and ECC is computed over GF（p） or GF（2P）. Moreover, embedded applications need advance encryption standard （AES） algorithms to pro- cess encryption and decryption procedures. In order to reuse the hardware resources and meet the trade-off between area and performance, we proposed a new triple functional arith- metic unit for computing high radix RSA and ECC operations over GF（p） and GF（2P）, which also can be extended to support AES operations. A new high radix signed digital （SD） adder has been proposed to eliminate the carry propagations over GF（p）. The proposed unified design took up 28.7% less hardware resources than implementing RSA, ECC, and AES individually, and the experimental results show that our proposed architecture can achieve 141.8 MHz using approxi- mately 5.5k CLBs on Virtex-5 FPGA.

关键词： AES RSA ECC signed-digit number FPGA cryptographic algorithms high radix arithmetic unit

Carbonyl sulfide and dimethyl sulfide fluxes in an urban lawn and adjacent bare soil in Guangzhou,China

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Journal of Environmental Sciences 2011年第5期23卷 784-789页

作者： Zhigang yi Xinming wang College of Resources and Environment Fujian Agriculture and Forestry University Fuzhou 350002 China. E-mail:zgyi@*** State Key Laboratory of Organic Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China

Carbonyl sulfide （COS） and dimethyl sulfide （DMS） fluxes from as urban Cynodon dactylon lawn and adjacent bare soil were measured during April-July 2005 in Guangzhou, China. Both the lawn and bare soil acted as sinks for COS and sources for DMS. The mean fluxes of COS and DMS in the lawn （-19.27 and 18.16 pmol/（m^***）, respectively） were significantly higher than those in the bare soil （-9.89 and 9.35 pmol/（m^***）, respectively）. Fluxes of COS and DMS in mowed lawn were also higher than those in bare soils. Both COS and DMS fluxes showed diurnal variation with detectable but much lower values in the nighttime than in the daytime. COS fluxes were related significantly to temperature and the optimal temperature for COS uptake was 29℃. While positive linear correlations were found between DMS fluxes and temperature. COS fluxes increased linearly with ambient COS mixing ratios, and had a compensation point of 336 ppt.

关键词： carbonyl sulfide dimethyl sulfide flux urban lawn

Local prediction of the chaotic fh-code based on LS-SVM

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Journal of Systems Engineering and Electronics 2008年第1期19卷 65-70页

作者： wang yi Guo Wei National Key Lab of Communication Univ. of Electronic Science and Technology of China Chengdu 610054 P. R. China

Support vector machine （SVM） is powerful to solve some problems such as nonlinear classification, function estimation and density estimation. To consider the chaotic fh （frequency hopping）-code＇s characters in chaotic dynamic system, the forecasting model of the support vector machine in combination with Takens＇ delay coordinate phase reconstruction of chaotic times is established and the least squares model for large-scale problems is used in local training for this model. Finally, a fh-code series generated by Logistic-Kent mapping is applied to verify the local prediction model. Simulation results show that the high accuracy and fault tolerant SVM model has an excellent performance in predicting the fh code, with a very low mean square error and a high relative coefficient.

关键词： support vector machine(SVM) fh code least squares(LS) prediction

H_-/H_∞ fault detection filter design for interval time-varying delays switched systems

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Journal of Systems Engineering and Electronics 2016年第4期27卷 878-886页

作者： Jiawei wang yi Shen Zhenhua wang Department of Control Science and Engineering Harbin Institute of Technology

The problem of the robust fault detection filter design for time-varying delays switched systems is considered in the framework of mixed H-/H∞. Firstly, the weighted H∞ performance index is utilized as the robustness performance, and the H- index is used as the sensitivity performance for obtaining the robust fault detection filter. Then a novel multiple Lyapunov-Krasovskii function is proposed for deriving sufficient existence conditions of the robust fault detection filter based on the average dwell time technique. By introducing slack matrix variable, the coupling between the Lyapunov matrix and system matrix is removed, and the conservatism of results is reduced. Based on the robust fault detection filter, residual is generated and evaluated for detecting faults. In addition, the results of this paper are dependent on time delays,and represented in the form of linear matrix inequalities. Finally,the simulation example verifies the effectiveness of the proposed method.

关键词： switched system average dwell time mixed H-/H∞ robust fault detection filter time-varying delay