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Lessons on mobile apps for COVID-19 from China

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Journal of Safety Science and Resilience 2021年第2期2卷 40-49页

作者： Sophia L.Zhou Xianhan Jia Samuel P.Skinner william yang Isabelle Claude Mass Academy of Math and Science Worcester Polytechnic Institute85 Prescott StreetWorcesterMA 01605United States Department of Computer Science Worcester Polytechnic Institute100 Institute RoadWorcesterMA 01609United States Department of Physics Worcester Polythenic Institute100 Institute RoadWorcesterMA 01609United States Department of Biomedical Engineering Worcester Polytechnic Institute100 Institute RoadWorcesterMA 10609United States

The COVID-19 pandemic has impacted the global society and human life *** countries have launched COVID-19 mobile apps with a wide range in how these apps *** it is hoped that these apps can assist in the fight against COVID-19,many are worried about user *** implemented“health code”systems,which assigned neighborhoods and citizens a specific health code,meant to indicate their risk of having been exposed to *** most widely used health code systems were hosted on the popular apps WeChat and Alipay,each with billions of *** experts argued that China’s use of mobile applications was essential to its successful combat against *** in this study are a summary of mobile technology usage in China,a review of previous studies of mobile technology in healthcare,and a brief survey of some existing mobile applications for COVID-19 that were *** included are outcomes of interviews with healthcare and public safety experts and a public survey to understand how mobile applications were used in China’s response to *** interviews revealed four important themes:personal privacy,community involvement,government involvement,and situational *** was found that a key concern was maintaining a balance between collecting and utilizing personal information,as well as protecting this *** addition,close collaboration between local communities and the national government was *** applications assisted in communication and coordination but did not replace the work of people such as delivery drivers and contact *** results also showed that there was room for improvement,especially accessibility for the elderly or those unfamiliar with *** results were obtained from our *** was interesting to find that the apps were mostly used for“accessing information on COVID-19.”In addition,respondents overwhelmingly identified“information”as the most valuable featur

关键词： Mobile apps COVID-19 response Survey Interview Lessons

Pathological conditions re-shape physiological Tregs into pathological Tregs

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Burns & Trauma 2015年第1期3卷 10-20页

作者： william Y yang Ying Shao Jahaira Lopez-Pastrana Jietang Mai Hong Wang Xiao-feng yang Centers for Metabolic Disease Research Cardiovascular Researchand Thrombosis ResearchDepartment of PharmacologyTemple University School of MedicineMERB 10593500 North Broad StreetPhiladelphiaPA 19140USA Department of Microbiology and Immunology Temple University School of MedicinePhiladelphiaPA 19140USA

CD4^(+)FOXP3^(+)regulatory T cells(Tregs)are a subset of CD4 T cells that play an essential role in maintaining peripheral immune tolerance,controlling acute and chronic inflammation,allergy,autoimmune diseases,and anti-cancer immune *** the past 20 years,a significant progress has been made since Tregs were first characterized in *** concepts and principles regarding Tregs generation,phenotypic features,subsets(tTregs,pTregs,iTregs,and iTreg35),tissue specificity(central Tregs,effector Tregs,and tissue resident Tregs),homeostasis(highly dynamic and apoptotic),regulation of Tregs by receptors for PAMPs and DAMPs,Treg plasticity(re-differentiation to other CD4 T helper cell subsets,Th1,Th2,Tfh,and Th17),and epigenetic regulation of Tregs phenotypes and functions have been *** this concise review,we want to briefly analyze these eight new progresses in the study of *** have also proposed for the first time a novel concept that“physiological Tregs”have been re-shaped into“pathological Tregs”in various pathological *** of the improvement in our understanding on this important cellular component about the immune tolerance and immune suppression would lead to the future development of novel therapeutics approaches for acute and chronic inflammatory diseases,allergy,allogeneic transplantation-related immunity,sepsis,autoimmune diseases,and cancers.

关键词： Regulatory T cells Immune suppression Epigenetic mechanisms Histone modifications Metabolic cardiovascular diseases

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新型LNG快速气化装置应用试验

天然气工业 2016年第12期36卷 108-112页

作者：严平 william yang 刘勤张歆悦曹伟武上海工程技术大学 CSIRO Mineral Resources 上海天然气管网有限公司

液化天然气(LNG)存在于低温高压环境,使用时必须先对其加热气化,因此LNG气化装置是不可缺少的重要装备,对LNG的高效利用具有至关重要的作用。为此,研发了一种新型LNG快速气化装置。该装置采用了已授权国家发明专利的气流旋水子、烟气循... 详细信息

液化天然气(LNG)存在于低温高压环境,使用时必须先对其加热气化,因此LNG气化装置是不可缺少的重要装备,对LNG的高效利用具有至关重要的作用。为此,研发了一种新型LNG快速气化装置。该装置采用了已授权国家发明专利的气流旋水子、烟气循环系统、注水系统等创新技术,确保了装置的运行安全、提高了运行效率。在实验室试验取得成功的基础上,设计制造了工业性应用装置,并进行了试验以验证装置设计的合理性。试验结果表明:(1)新型LNG快速气化装置的效率、排烟损失、散热损失、自身燃料耗气率等都达到了设计要求,当负荷为1 800~2 200 m^3/h时,效率均超过95%;当负荷为1 976.0 m^3/h接近设计负荷2 000m^3/h时,效率为96.34%,最大负荷可达2 800 m^3/h;(2)装置的负荷适应性强,且能适应外界用气负荷迅速增大的情况;(3)该装置的自身燃料耗气率低,仅为1.5%,符合节能要求。结论认为,该装置热效率高、启动快、气化速率高、结构紧凑、占地面积小,不受环境条件影响,适用于天然气供气管网中因各种原因无法连网的相对独立的中小规模区域。

关键词：新型LNG气化装置启动快气化速率高伞型气流旋水子烟气循环注水系统应用试验

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90°弯管内气固两相流湍流变动实验研究

水动力学研究与进展（A辑） 2010年第4期25卷 559-565页

作者：张洪军赵周林 yang william TU Jiyuan 何春生中国计量学院流体检测与仿真研究所杭州310018 School of Aerospace Mechanical and Manufacturing Engineering RMIT University Vic. 3083 Australia Commonwealth Scientific and Industrial Research Organisation Clayton South Vic. 3169 Australia

采用相位多普勒测速仪(PDA)对方形截面90°弯管内稀相气固两相流动进行了测量。颗粒相采用平均粒径为77μm的玻璃球,气相测量采用雾化水滴为示踪粒子。实验雷诺数Re=105(平均速度U0=10m/s)。文中对单相气体流动和气粒流中气相流动进行... 详细信息

采用相位多普勒测速仪(PDA)对方形截面90°弯管内稀相气固两相流动进行了测量。颗粒相采用平均粒径为77μm的玻璃球,气相测量采用雾化水滴为示踪粒子。实验雷诺数Re=105(平均速度U0=10m/s)。文中对单相气体流动和气粒流中气相流动进行了分析。其中,两相流动中气相流动数据是在PDA激光散射信号后处理过程中根据颗粒尺寸进行大小颗粒(小颗粒代表气相,大颗粒代表颗粒相)分离得到的。结果发现,平均流速方面气粒流动中的气相速度较单相气体流动低,此现象产生的原因,主要是由于颗粒对连续气相介质的拖拽作用;对于湍流脉动,两相流中气相的湍流脉动比单相气体流动大,这主要是因为动能较大的颗粒相把动能传递给了气相,而这些颗粒的动能主要来源于壁面或颗粒间的碰撞。

关键词：相位多普勒测速仪PDA 90°弯管稀相气固两相流湍流变动

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Determination of esophageal squamous cell carcinoma and gastric adenocarcinoma on raw tissue using Raman spectroscopy

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World Journal of Gastroenterology 2023年第20期29卷 3145-3156页

作者： Hiroaki Ito Naoyuki Uragami Tomokazu Miyazaki Yuto Shimamura Haruo Ikeda Yohei Nishikawa Manabu Onimaru Kai Matsuo Masayuki Isozaki william yang Kenji Issha Satoshi Kimura Machiko Kawamura Noboru Yokoyama Miki Kushima Haruhiro Inoue Digestive Disease Center Showa University Koto Toyosu HospitalTokyo 135-8577Japan JSR Corporation Tokyo 105-0021Japan Bay Spec Inc. San JoseCA 95131United States Fuji Technical Research Inc. Yokohama 220-6215Japan Department of Laboratory Medicine and Central Clinical Laboratory Showa University Northern Yokohama HospitalYokohama 224-8503Japan Department of Hematology Saitama Cancer CenterInamachi 362-0806Japan Department of Pathology Showa University Koto Toyosu HospitalTokyo 135-8577Japan

BACKGROUND Cancer detection is a global research focus,and novel,rapid,and label-free techniques are being developed for routine clinical *** has led to the development of new tools and techniques from the bench side to routine clinical *** this study,we present a method that uses Raman spectroscopy(RS)to detect cancer in unstained formalin-fixed,resected specimens of the esophagus and *** method can record a clear Raman-scattered light spectrum in these specimens,confirming that the Raman-scattered light spectrum changes because of the histological differences in the mucosal *** To evaluate the use of Raman-scattered light spectrum for detecting endoscopically resected specimens of esophageal squamous cell carcinoma(SCC)and gastric adenocarcinoma(AC).METHODS We created a Raman device that is suitable for observing living tissues,and attempted to acquire Raman-scattered light spectra in endoscopically resected specimens of six esophageal tissues and 12 gastric *** evaluated formalin-fixed tissues using this technique and captured shifts at multiple locations based on feasibility,ranging from six to 19 locations 200 microns apart in the vertical and horizontal ***,a correlation between the obtained Raman scattered light spectra and histopathological diagnosis was *** We successfully obtained Raman scattered light spectra from all six esophageal and 12 gastric *** data capture,the tissue specimens were sent for histopathological analysis for further processing because RS is a label-free methodology that does not cause tissue destruction or *** on data analysis of molecular-level substrates,we established cut-off values for the diagnosis of esophageal SCC and gastric *** analyzing specific Raman shifts,we developed an algorithm to identify the range of esophageal SCC and gastric AC with an accuracy close to that of histopathological *** Our technique pr

关键词： Raman spectroscopy Squamous cell carcinoma Adenocarcinoma Esophagus Stomach Labelfree cancer detection Real-time diagnosis

Highly accurate colorectal cancer prediction model based on Raman spectroscopy using patient serum

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World Journal of Gastrointestinal Oncology 2020年第11期12卷 1311-1324页

作者： Hiroaki Ito Naoyuki Uragami Tomokazu Miyazaki william yang Kenji Issha Kai Matsuo Satoshi Kimura Yuji Arai Hiromasa Tokunaga Saiko Okada Machiko Kawamura Noboru Yokoyama Miki Kushima Haruhiro Inoue Takashi Fukagai Yumi Kamijo Digestive Disease Center Showa University Koto Toyosu HospitalTokyo 135-8577Japan Research Division JSR CorporationTokyo 105-0021Japan BaySpec Inc. San JoseCA 95131United States Fuji Technical Research Inc. Yokohama 220-6215Japan Department of Laboratory Medicine and Central Clinical Laboratory Showa University Northern Yokohama HospitalYokohama 224-8503Japan Department of Clinical Laboratory Showa University Koto Toyosu HospitalTokyo 135-8577Japan Department of Clinical Laboratory Showa University HospitalTokyo 142-8555JapanBML Inc.Tokyo 151-0051Japan Department of Hematology Saitama Cancer CenterInamachiSaitama 362-0806Japan Department of Pathology Showa University Koto Toyosu HospitalTokyo 135-8577Japan Department of Urology Showa University Koto Toyosu HospitalTokyo 135-8577Japan Showa University Koto Toyosu Hospital Tokyo 135-8577Japan

BACKGROUND Colorectal cancer(CRC) is an important disease worldwide, accounting for the second highest number of cancer-related deaths and the third highest number of new cancer cases. The blood test is a simple and minimally invasive diagnostic test. However, there is currently no blood test that can accurately diagnose *** To develop a comprehensive, spontaneous, minimally invasive, label-free, bloodbased CRC screening technique based on Raman *** We used Raman spectra recorded using 184 serum samples obtained from patients undergoing colonoscopies. Patients with malignant tumor histories as well as those with cancers in organs other than the large intestine were excluded. Consequently, the specific diseases of 184 patients were CRC(12), rectal neuroendocrine tumor(2), colorectal adenoma(68), colorectal hyperplastic polyp(18), and others(84). We used the 1064-nm wavelength laser for excitation. The power of the laser was set to 200 *** Use of the recorded Raman spectra as training data allowed the construction of a boosted tree CRC prediction model based on machine learning. Therefore, the generalized R^2 values for CRC, adenomas, hyperplastic polyps, and neuroendocrine tumors were 0.9982, 0.9630, 0.9962, and 0.9986, *** For machine learning using Raman spectral data, a highly accurate CRC prediction model with a high R^2 value was constructed. We are currently planning studies to demonstrate the accuracy of this model with a large amount of additional data.

关键词： Colorectal cancer Raman spectroscopy Machine learning Blood Serum Diagnosis

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无限影像

数字生活 2004年第7期 74-79页

作者： william o.yang

数码影像的发展是空前的,这使得数码厂商不断更新产品,人们也在不断热衷于此.但往往有时一些好的创意更能吸引人们的目光……

关键词：电影节金属质感数码相机

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Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong Li Li Dan Jing Peng Qidong yang Fuqiang yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 *** results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the *** higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in *** flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through *** occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.

关键词： Carbon variability ENSO modulation CMIP6 models

High-temperature-tolerant flexible supercapacitors: Gel polymer electrolytes and electrode materials

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Journal of Energy Chemistry 2025年第1期100卷 426-457页

作者： Chong Peng Xinyi Huang Mingwei Zhao Shuling Liao Quanhong yang Nianjun yang Siyu Yu School of Chemistry & Chemical Engineering Southwest University Nanoyang Group Tianjin Key Laboratory of Advanced Carbon and Electrochemical Energy Storage School of Chemical Engineering and Technology and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin University Department of Chemistry & IMO-IMOMEC Hasselt University

The development of flexible supercapacitors(FSCs) capable of operating at high temperatures is crucial for expanding the application areas and operating conditions of supercapacitors. Gel polymer electrolytes and electrode materials stand as two key components that significantly impact the efficacy of hightemperature-tolerant FSCs(HT-FSCs). They should not only exhibit high electrochemical performance and excellent flexibility, but also withstand intense thermal stress. Considerable efforts have been devoted to enhancing their thermal stability while maintaining high electrochemical and mechanical performance. In this review, the fundamentals of HT-FSCs are outlined. A comprehensive overview of state-of-the-art progress and achievements in HT-FSCs, with a focus on thermally stable gel polymer electrolytes and electrode materials is provided. Finally, challenges and future perspectives regarding HT-FSCs are discussed, alongside strategies for elevating operational temperatures and *** review offers both theoretical foundations and practical guidelines for designing and manufacturing HT-FSCs, further promoting their widespread adoption across diverse fields.

关键词： Flexible supercapacitors High-temperature tolerance Gel polymer electrolytes Electrode materials