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A 3D In-vitro model of the human dentine interface shows long-range osteoinduction from the dentine surface

International Journal of oral Science 2024年第2期16卷 225-237页

作者： william Macalester Asme Boussahel Rafael o.Moreno-Tortolero Mark R.Shannon Nicola West Darryl Hill Adam Perriman School of Cellular and Molecular Medicine Biomedical Sciences BuildingUniversity of BristolUniversity WalkBristolUnited Kingdom Bristol Centre for Functional Nanomaterials HH Wills Physics LaboratoryUniversity of BristolTyndall AvenueBristolUnited Kingdom Centre for Protolife Research School of ChemistryUniversity of BristolCantocks CloseBristolUnited Kingdom Max Planck-Bristol Centre for Minimal Biology School of ChemistryUniversity of BristolBristolUnited Kingdom Periodontology Bristol Dental SchoolUniversity of BristolLower Maudlin StreetBristolUnited Kingdom

Emerging regenerative cell therapies for alveolar bone loss have begun to explore the use of cell laden hydrogels for minimally invasive surgery to treat small and spatially complex maxilla-oral ***,the oral cavity presents a unique and challenging environment for in vivo bone tissue engineering,exhibiting both hard and soft periodontal tissue as well as acting as key biocenosis for many distinct microbial communities that interact with both the external environment and internal body systems,which will impact on cell fate and subsequent treatment ***,we design and bioprint a facile 3D in vitro model of a human dentine interface to probe the effect of the dentine surface on human mesenchymal stem cells(hMSCs)encapsulated in a microporous hydrogel *** demonstrate that the dentine substrate induces osteogenic differentiation of encapsulated hMSCs,and that both dentine andβ-tricalcium phosphate substrates stimulate extracellular matrix production and maturation at the gel-media interface,which is distal to the gel-substrate *** findings demonstrate the potential for long-range effects on stem cells by mineralized surfaces during bone tissue engineering and provide a framework for the rapid development of 3D dentine-bone interface models.

关键词： interface den surface

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Comment on profitability analysis of a femtosecond laser system for cataract surgery using a fuzzy logic approach

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International Journal of ophthalmology(English edition) 2017年第3期10卷 497-498页

作者： Harrv william Roberts Melody Zhifang Ni David Phillip S. o'Brart Department of ophthalmology Guy's and St. Thomas' NHS Foundation Trust London SE1 7ET UK King's College London London WC2R 2LS UK 3Division of Surgery Department of Surgery and Cancer Imperial College London St Mary's Hospital London W2 1NY UK Division of Surgery Department of Surgery and CancerImperial College London St Mary's Hospital London W21NY UK

Dear Editor,We read with interest the recently published study by Trigueros et al（[1]）,highlighting the financial and management conditions of femtosecond laser-assisted cataract surgery（FLACS）.The authors derived... 详细信息

关键词： cataract operations carefully nothing something enough sparse currently details comment

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Fathal pulmonary hypertension after distal splenorenal shunt in schistosomal portal hypertension

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World Journal of Gastroenterology 2004年第12期10卷 1836-1837页

作者： Roberto de Cleva Paulo Herman Vincenzo Pugliese Bruno Zilberstein william Abro Saad Joaquim JoséGama-Rodrigues Gastroenterology Department Hospital Das Clinicas-University of Sao Paulo Medical School Digestive Tract Surgery Division Hospital Das Clinicas-University of Sao Paulo Medical School Digestive Tract Surgery Division Hospital Das Clincas-University of Sao Paulo Medical School

Mansonic schistosomiasis is the main cause of portal hypertension in Brazil. Hepatosplenic (HS) form is manifested by hepatomegaly mainly on the left hepatic lobe associated with large splenomegaly and bleeding due to... 详细信息

关键词： Adult Fatal outcome Female Humans Hypertension, Portal Hypertension, Pulmonary Male Postoperative Complications Schistosomiasis mansoni Splenorenal Shunt, Surgical

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应用CRISP清单,提升我国全科医学和基本医疗研究报告的质量

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中国全科医学 2025年第4期28卷 393-401页

作者：杨辉汪洋陈庆奇刘晨曦顾杰赵洋秦江梅曹新阳 Elizabeth Sturgiss william R.Phillips 许岩丽 Monash大学公共卫生与预防医学学院澳大利亚墨尔本市VIC 3168 上海市全科医学与社区卫生发展研究中心 200090 同济大学附属杨浦医院全科医学科上海市200090 香港大学家庭医学及基层医疗学系中国香港特别行政区999077 华中科技大学同济医学院医药卫生管理学院湖北省武汉市430000 复旦大学附属中山医院全科医学科上海市200032 复旦大学附属中山医院国际医疗部上海市200032 新南威尔士大学乔治全球健康研究院澳大利亚悉尼2050 墨尔本大学人口与全球健康学院澳大利亚墨尔本3010 国家卫生健康委卫生发展研究中心北京市100044 《中国全科医学》杂志社有限公司北京市100053 School of Primary and Allied Health Care Monash UniversityMelbourneVictoriaAustraliaVIC 3168 University of Washington SeattleWashington98195

基本医疗(初级保健)研究报告内容的条目共识(CRISP)工作组于2023年提出了CRISP清单,以支持改善上述领域研究报告的质量、实用性和传播性。《中国全科医学》英文版的学术编辑团队对CRISP清单进行了中文翻译,并通过这篇述评,在回顾我国全... 详细信息

基本医疗(初级保健)研究报告内容的条目共识(CRISP)工作组于2023年提出了CRISP清单,以支持改善上述领域研究报告的质量、实用性和传播性。《中国全科医学》英文版的学术编辑团队对CRISP清单进行了中文翻译,并通过这篇述评,在回顾我国全科医学和基本医疗研究的内涵和发展现状的基础上,归纳了该领域的科研报告中目前存在的主要问题,如“以作者为中心”“过度重视塑造权威性”“盲目生搬国际经验”“缺乏对方法学的透明报告”“在论文中压入大量冗繁信息”以及“遮蔽关键信息”等。最后,编辑团队推荐和鼓励中国的全科医学和基本医疗服务研究的作者、编辑和学术评议专家尝试使用CRISP清单,在改善中国全科医学和基本医疗研究报告质量的同时,进一步完善该工具在学科发展研究、临床研究、卫生服务研究、卫生政策研究、教育和培训研究以及社区流行病学研究等亚领域中的应用。

关键词：全科医学基本医疗研究报告内容共识

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Rethinking the definition of the word‘map’:an evaluation of Beck’s representation of the London Underground through a qualitative expert survey

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International Journal of Digital Earth 2015年第7期8卷 522-537页

作者： william Cartwright School of Mathematical and Geospatial Sciences RMIT UniversityMelbourneVICAustralia

This paper reports on the results from a qualitative expert survey of members of the international geospatial community to elicit their view of Henry(Harry)Beck’s iconic 1931 representation of the London *** begins by providing a background to the publishing era when Beck’s representation was developed under the‘umbrella’of the design style adopted by the London Passenger Transport Board to promote the image of‘the new’and contemporary *** then outlines Beck’s representation and his quest to develop a clearer and more understandable graphic information *** is followed by an overview of representative views from the design community about Beck’s ***,it provides the results of research undertaken with an informed international cartographic community to determine whether they viewed the product as a map or a *** is important to understand how Beck’s representation is viewed from the perspective of the geospatial *** it works as a map,albeit one where geography is generally abandoned,relative positions are favoured over the absolute and azimuth is distorted,then the view that successful(geo)communication artefacts must be linked to map designs that focus on precise and true representations of geographic information can be questioned.

关键词： maps diagrams design

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Metal-assisted chemical etching of silicon and the behavior of nanoscale silicon materials as Li-ion battery anodes

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Nano Research 2015年第5期8卷 1395-1442页

作者： william McSweeney Department of Chemistry University College Cork Cork Ireland Department of Physics and Energy University of Limerick Limerick Ireland Materials and Surface Science Institute University of Limerick Limerick Ireland Micro & Nanoelectronics Centre Tyndall National Institute Lee Maltings Cork Ireland

This review outlines the developments and recent progress in metal-assisted chemical etching of silicon, summarizing a variety of fundamental and innovative processes and etching methods that form a wide range of nanoscale silicon structures. The use of silicon as an anode for Li-ion batteries is also reviewed, where factors such as film thickness, doping, alloying, and their response to reversible lithiation processes are summarized and discussed with respect to battery cell performance. Recent advances in improving the performance of silicon-based anodes in Li-ion batteries are also discussed. The use of a variety of nanostructured silicon structures formed by many different methods as Li-ion battery anodes is outlined, focusing in particular on the influence of mass loading, core-shell structure, conductive additives, and other parameters. The influence of porosity, dopant type, and doping level on the electrochemical response and cell performance of the silicon anodes are detailed based on recent findings. Perspectives on the future of silicon and related materials, and their compositional and structural modifications for energy storage via several electrochemical mechanisms, are also provided.

关键词： silicon Li-ion battery nanostructures nanowires electrochemistry energy storage etching

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Functionals for Multilinear Fractional Embedding

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Acta Mathematica Sinica,English Series 2015年第1期31卷 1-28页

作者： william BECKNER Department of Mathematics The University of Texas at Austin 1 University Station C1200Austin TX 78712-0257 USA

A novel representation is developed as a measure for multilinear fractional embedding. Corresponding extensions are given for the Bourgain-Brezis-Mironescu theorem and Pitt＇s inequal- ity. New results are obtained for diagonal trace restriction on submanifolds as an application of the Hardy-Littlewood-Sobolev inequality. Smoothing estimates are used to provide new structural un- derstanding for density functional theory, the Coulomb interaction energy and quantum mechanics of phase space. Intriguing connections are drawn that illustrate interplay among classical inequalities in Fourier analysis.

关键词： Fractional embedding Hardy-Littlewood-Sobolev inequality diagonal trace restriction,Coulomb interaction Pitt's inequality

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Expansion properties for finite subdivision rules I Dedicated to the Memories of william P. Thurston and Lei Tan

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Science China Mathematics 2018年第12期61卷 2237-2266页

作者： william J.Floyd Walter R.Parry Kevin M.Pilgrim Department of Mathematics Virginia Tech Department of Mathematics and Statistics Eastern Michigan University Department of Mathematics Indiana University

Among Thurston maps (orientation-preserving, postcritically finite branched coverings of the 2-sphere to itself), those that arise as subdivision maps of a finite subdivision rule form a special family. For such maps, we investigate relationships between various notions of expansion—combinatorial, dynamical, algebraic,and coarse-geometric.

关键词： finite subdivision rule expanding map postcritically finite Thurston map

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Toward understanding Cretaceous climate An updated review

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Science China Earth Sciences 2017年第1期60卷 5-19页

作者： william W. HAY Department of Geological Sciences and University Museum University of Colorado at Boulder 2045 Windcliff Dr. Estes Park CO 80517 USA

New data and ideas are changing our view of conditions during the *** of the continents was lower than originally thought,eliminating the'cold continental interior paradox'of fossils of plants that could not tolerate freezing occurring in regions indicated by climate models to be well below freezing in *** controversy over the height of Cretaceous sea levels has been resolved by knowledge of the effects of passage of the subducted slab of the Farallon Plate beneath the North American *** cause of shorter term sea level changes of the order of 30 to 50 meters is not because of growth and decay of ice sheets,but more likely the filling and release of water from groundwater reservoirs and lakes although there may have been some ice in the Early and latest *** dioxide was not the only significant greenhouse gas;methane contributed significantly to the warmer *** of very warm tropical ocean temperatures(>40℃)have implications for the nature of plant life on land limited by Rubisco *** land surfaces were much wetter than has been thought,with meandering rivers and many oxbow lakes providing habitat for large dinosaurs.A major rethinking of the nature of conditions on a warmer Earth is underway,and a new suite of paleoclimate simulations for the Cretaceous is needed.

关键词： Cretaceous Paleogeography Paleotopography Sea level Greenhouse Paleohydrology Paleoclimate

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Arsenobetaine and thio-arsenic species in marine macroalgae and herbivorous animals: Accumulated through trophic transfer or produced in situ?

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Journal of Environmental Sciences 2016年第11期28卷 131-139页

作者： Simon Foster william Maher Ecochemistry Laboratory Institute for Applied Ecology University of Canberra

Arsenobetaine（AB） and thio-arsenoribosides were measured in common macroalgae species（8 phaeophyta, 4 rhodophyta and 2 chlorphyta）, along the Australian south east coast line. As well, arsenic species profiles were measured for two common marine herbivores, the sea urchin Centrostephanus rodgersii and the fish odax cyanomelas that graze on these macroalgae to understand if trophic transfer of these species would account for their presence in marine herbivores. AB was found in seven of the fourteen macroalgae species investigated but does not contributed significantly to any of the macroalgae arsenic content（0.01-1.2 μg/g）. AB was found in only two of the brown macroalgae and all the red and green macroalgae（with the exception of Corallina officinalis）. Thio-arsenic species were found sporadically, but not in high concentrations in any of the macroalgae *** present in macroalgae is likely to be associated with epiphytic organisms while thio-arsenoribosides are likely to be produced by decaying parts of damaged macroalgae.A laboratory feeding experiment in which the herbivorous gastropod, Austrocochlea constricta, was fed macroalgae containing thio-arsenoribosides for a 24 hr period every three days showed that these are readily accumulated over a short period. Thio-arsenoribosides in herbivores are therefore probably obtained through trophic transfer. Some AB is also obtained through trophic transfer; however, the presence of trimethylated arsonioribosides,a hypothesized precursor of AB formation in herbivores, suggests that some AB is produced within herbivores from the transformation of arsenoribosides accumulated from their diet.

关键词： Arsenobetaine Arsenic Metabolism Thio-arsenosugars Macroalgae Gastropods

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