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Performance characterization of Ni60-WC coating on steel processed with supersonic laser deposition

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Defence Technology（防务技术） 2015年第1期11卷 35-47页

作者： Fang LUo Andrew CoCKBURN Martin SPARKES Rocco LUPoI Zhi-jun CHEN william o'neill Jian-hua YAo Rong LIU College of Zhijiang Zhejiang University of Technology Institute for Manufacturing Department of Engineering University of Cambridge Department of Mechanical & Manufacturing Engineering Trinity College Dublin College of Mechanical Engineering Zhejiang University of Technology Department of Mechanical & Aerospace Engineering Carleton University 1125 Colonel By Drive Ottawa Ontario K1S 5B6 Canada

Ni60-WC particles are used to improve the wear resistance of hard-facing steel due to their high hardness. An emerging technology that combines laser with cold spraying to deposit the hard-facing coatings is known as supersonic laser deposition. In this study, Ni60-WC is deposited on low-carbon steel using SLD. The microstructure and performance of the coatings are investigated through SEM, optical microscopy, EDS, XRD, microhardness and pin-on-disc wear tests. The experimental results of the coating processed with the optimal parameters are compared to those of the coating deposited using laser cladding.

关键词： Ni60-WC Supersonic laser deposition Laser cladding Microstructure Wear

Using 3D-Printed Models to Advance Clinical Care

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Cardiovascular Innovations and Applications 2019年第B04期4卷 53-61页

作者： Molly Pantelic Milan Pantelic,MD Todd Pietila Marianne Rollet Eric Myers Thomas Song,MD william W.o’neill,MD Dee Dee Wang,MD,FACC,FASE,FSCCT Center for Structural Heart Disease Division of CardiologyHenry Ford Health System2799 West Grand BoulevardDetroitMI 48202USA Department of Radiology Henry Ford Health System2799 West Grand BoulevardDetroitMI 48202USA Materialise 44650 Helm CtPlymouthMI 48170USA Henry Ford Innovation Institute Henry Ford Health System2799 West Grand BoulevardDetroitMI 48202USA

Structural Heart is a new fi eld within the division of cardiovascular service *** heart has broadened the scope of delivery of cardiovascular care with its ability to deliver new valves and devices to heart patients who were once turned down for traditional open-heart surgery through the use of transcatheter delivery systems and device ***,in the absence of an open-surgical fi eld,the main limitation in transcatheter device development and patient-centric care is the inability of the Structural Heart Implanter to palpate the patient’s cardiac anatomy for device sizing and *** of 3D printing and 3D modeling are becoming a useful toolkit for Structural Heart Implanters,Imagers,and Device specialists within the Heart Team to use as a communication tool and case planning resource to optimize patient care,and patient *** interventions have revolutionized not only the fi eld of cardiology,but additionally the fi eld of biomedical engineering within Cardiovascular Medicine through the incorporation of 3D simulation technology.

关键词： 3D printing Left atrial appendage transcatheter mitral valve structural heart TAVR

Neuroprotection by resveratrol-glucuronide and quercetin-glucuronide via binding to polyphenol-and glycosaminoglycan-binding sites in the laminin receptor

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Neural Regeneration Research 2025年第3期20卷 819-820页

作者： Rayudu Gopalakrishna Jennifer Aguilar Emily Lee william J.Mack Department of Integrative Anatomical Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ... 详细信息

关键词： resveratrol molar dated

Characteristics of Stellite 6 Deposited by Supersonic Laser Deposition Under optimized Parameters

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Journal of Iron and Steel Research International 2013年第2期20卷 52-57页

作者： LUo Fang Lupoi Rocco Cockburn Andrew Sparkes Martin o'neill william YAo Jian-hua College of Zhijiang Zhejiang University of Technology College of Mechanical Engineering Zhejiang University of Technology Department of Mechanical and Manufacturing Engineering Trinity College Dublin Institute for Manufacturing Department of EngineeringUniversity of Cambridge

Stellite 6 powders were deposited on low carbon steel using SLD （supersonic laser deposition） under optimized parameters. The structure, line scan of elements and porosity of coating were examined and analyzed using SEM （scanning electron microscope）, oM （optical microscope） and XRD （X-ray diffraction）. The adhesion strength between coating and substrate was tested by PAT-ADHESIoN/TENSILE and E900STM adhesive. The results showed the deposition characteristics of optimized coating with N2 at a pressure of 3.0 MPa, a temperature of 450 ℃ and a laser power of 1.5 kW were compared with those of Stellite 6 coating deposited by the HVoF （high velocity oxygen fuel）.

关键词： Stellite 6 supersonic laser deposition deposition characteristic HVoF

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： william J.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

A comprehensive simulation-based assessment of office building performance adaptability to teleworking scenarios in different Canadian climate zones

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Building Simulation 2022年第6期15卷 995-1014页

作者： Farzam Kharvari Sara Azimi william o’Brien Department of Civil and Environmental Engineering Carleton University1125 Colonel by DriveOttawaOntarioK1S 5B6Canada

Recent studies have shown that office building systems do not adapt well to partial occupancy(e.g.,from teleworking)and thus perform *** a result,this study aims to assess office building performance adaptability by investigating the impact of four different technologies,including occupancy-based lighting,smart plugs(occupancy-based plug load),demand-controlled ventilation(DCV),occupancy-based thermostat,and their cumulative effect in office buildings in six different Canadian climates.A three-story office building is simulated in EnergyPlus version 9.3.0 under five occupancy scenarios,including 0%occupancy,100%occupancy,50%uniformly distributed occupancy across the floor,50%consolidated occupancy scenario where occupants work in core zones,and 50%consolidated occupancy scenario where occupants work in perimeter *** results are compared using energy use intensity(EUI),energy use intensity per occupant(EUP),and the corresponding greenhouse gas(GHG)emissions.A total of 180 simulations demonstrate the occupancy-adaptive technologies are generally most beneficial for low occupancy scenarios and milder *** results also show the cumulative impact of all these technologies on the potential energy savings is significant in the climates under ***,the results show office buildings can improve their performance adaptability during partial occupancy by implementing the studied *** from filling in the current knowledge gap in the literature on partial occupancy,the for the first time results of this study systemically demonstrate how each technology performs under different partial occupancy scenarios and how they perform together at each climate.

关键词： partial occupancy thermostat setpoint smart plug demand-controlled ventilation(DCV) lighting

Measuring magnetic declination with a compass, virtual globes and a global positioning system

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International Journal of Digital Earth 2009年第1期2卷 31-43页

作者： william P.o’Brien Jr Physics Department Southwestern UniversityGeorgetownTexas78626USA

Earth’s magnetic declination was experimentally measured at 15 sites in western USA from Alaska to Texas;each site exhibited a large linear feature identifiable in virtual globe imagery(NASA’s World Wind or Google Earth).The difference between the geographic bearing of the linear feature measured directly on a virtual globe image and the magnetic bearing of the same linear feature measured on the ground with a compass defines the magnetic declination d for that *** all 15 sites,d values,determined by this differencing procedure,ranged from about 208 to 58 E and fell within 18(over half within 0.58)of expected *** positioning system(GPS)data recorded at most sites and plotted on virtual globe images aided in the identification of relevant *** straightforward method for determining magnetic declination using virtual globe software and a compass provides a contemporary geospatial field/laboratory activity that dramatically elucidates and contrasts features of magnetic and geographic coordinate systems for students in various disciplines involving geomagnetism,navigation,geography or spherical polar geometry.

关键词： Earth observation GPS magnetic declination geophysics

Archaea and the human gut:New beginning of an old story

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World Journal of Gastroenterology 2014年第43期20卷 16062-16078页

作者： Nadia Gaci Guillaume Borrel william Tottey Paul william o’Toole Jean-Fran?ois Brugère EA-4678 CIDAM Clermont UniversitéUniversité d’AuvergneF-63000 Clermont-FerrandFrance School of Microbiology and Alimentary Pharmabiotic Centre University College CorkCorkIreland

Methanogenic archaea are known as human gut inhabitants since more than 30 years ago through the detection of methane in the breath and isolation of two methanogenic species belonging to the order Methanobacteriales, Methanobrevibacter smithii and Methanosphaera stadtmanae. During the last decade, diversity of archaea encountered in the human gastrointestinal tract (GIT) has been extended by sequence identification and culturing of new strains. Here we provide an updated census of the archaeal diversity associated with the human GIT and their possible role in the gut physiology and health. We particularly focus on the still poorly characterized 7th order of methanogens, the Methanomassiliicoccales, associated to aged population. While also largely distributed in non-GIT environments, our actual knowledge on this novel order of methanogens has been mainly revealed through GIT inhabitants. They enlarge the number of final electron acceptors of the gut metabolites to mono- di- and trimethylamine. Trimethylamine is exclusively a microbiota-derived product of nutrients (lecithin, choline, TMAo, L-carnitine) from normal diet, from which seems originate two diseases, trimethylaminuria (or Fish-odor Syndrome) and cardiovascular disease through the proatherogenic property of its oxidized liver-derived form. This therefore supports interest on these methanogenic species and its use as archaebiotics, a term coined from the notion of archaea-derived probiotics.

关键词： Human gut microbiota Methanogens Methanomassiliicoccus Methanomethylophilus Trimethylaminuria Trimethylamine Methane Cardiovascular disease Archaebiotics Probiotics

Eye contact and sociability data suggests that Australian dingoes were never domesticated

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Current Zoology 2022年第4期68卷 423-431页

作者： J william o Ballard Chloe Gardner Lucille Ellem Sonu Yadav Richard I Kemp Department of Ecology Environmentand EvolutionLatrobe UniversityMelbourneVIC 3086Australia Department of BioSciences The University of MelbourneMelbourneVIC 3010Australia School of Life and Environmental Sciences University of SydneyCamperdownNSW 2006Australia Bargo Dingo Sanctuary BargoNSW 2574Australia School of Biotechnology and Biomolecular Sciences UNSW SydneySydneyNSW 2052Australia School of Psychology UNSW SydneySydneyNSW 2052Australia

Dogs were the first animal to become domesticated by humans,and they represent a classic model system for unraveling the processes of *** compare Australian dingo eye contact and socialization with Basenji and German Shepherd dog(GSD)*** dingoes arrived in Australia 5,000–8,000 BP,and there is debate whether they were domesticated before their *** Basenji represents a primitive breed that diverged from the remaining breeds early in the domestication process,while GSDs are a breed dog selected from existing domestic dogs in the late *** conducted a 4-phase study with unfamiliar and familiar investigators either sitting passively or actively calling each *** found 75%of dingoes made eye contact in each *** contrast,86%of Basenjis and 96%of GSDs made eye *** also exhibited shorter eye-gaze duration than breed dogs and did not respond to their name being called ***,quantified as a canid coming within 1m of the experimenter,was lowest for dingoes and highest for *** sociability duration,dingoes spent less time within 1m of the experimenter than either breed *** compared with previous studies,these data show that the dingo is behaviorally intermediate between wild wolves and Basenji dogs and suggest that it was not domesticated before it arrived in ***,it remains possible that the accumulation of mutations since colonization has obscured historical behaviors,and dingoes now exist in a feralized retamed *** morphological and genetic data are required to resolve this conundrum.

关键词： Basenji dingo domestication German Shepherd dog eye gaze sociability