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Downhill running impairs peripheral but not central neuromuscular indices in elbow flexor muscles

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Sports medicine and Health Science 2021年第2期3卷 101-109页

作者： Xin Ye Robert J.Benton william m.miller Sunggun Jeon Jun Seob Song Department of Rehabilitation Sciences University of HartfordWest HartfordCTUSA Department of Health Exercise Scienceand Recreation ManagementUniversity of MississippiUniversityMSUSA School of Kinesiology Applied Health and RecreationOklahoma State UniversityStillwaterOKUSA

The purpose of this study was to examine the effects of a 1-h downhill running exercise on the elbow flexor muscles’neuromuscular *** adults(Control[CON]:n=9;Experimental[EXP]:n=8)completed this *** CON rested for 30 min while the EXP performed the downhill ***,10 min,24 h,and 48 h after the interventions,dependent variables(knee extensor muscle soreness,elbow flexion and knee extension isometric strength,elbow flexion resting twitch and voluntary activation[VA],and the biceps surface electromyography[EmG]amplitude)were *** extensor muscle soreness was significantly greater in the EXP than the CON group following the intervention throughout the entire 48 *** was accompanied by the greater decline in the knee extension strength in the EXP than the CON(mean±SD:-6.9±3.4%vs.1.0±3.2%,p=0.044).The elbow flexion strength,VA,and EmG amplitude were not affected by the ***,the decline of the elbow flexion resting twitch was greater in the EXP than the CON(±19.6±6.3%vs.8.7±5.9%,p=0.003).Therefore,the downhill running impaired the remote elbow flexor muscles at a peripheral level.

关键词： muscle damage Twitch interpolation Voluntary activation Surface EmG Non-local effect

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SOI辐射效应测试技术

微电子学 1988年第1期 28-31页

作者： william m.miller,刘昌第国立桑迪亚实验室

我们已经研究和验证了一种测试绝缘体上硅（SOI）材料界面的辐射响应技术,它采用全SOI结构和深腐蚀SOI结构电容电压（C-V）曲线数据叠合法得到三个界面各自的C-V曲线。根据这些C-V曲线,就可以测定SiO2俘获电荷和界面态。此技术可作为对... 详细信息

我们已经研究和验证了一种测试绝缘体上硅（SOI）材料界面的辐射响应技术,它采用全SOI结构和深腐蚀SOI结构电容电压（C-V）曲线数据叠合法得到三个界面各自的C-V曲线。根据这些C-V曲线,就可以测定SiO2俘获电荷和界面态。此技术可作为对不同SOI材料的辐射响应进行比较的一种方法。本文中,我们是检测总剂量辐射对融熔再结晶法制备的SOI材料的影响。

关键词： SOI 电荷再结晶辐射效应界面态

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： william J.Flerlage mark L.Dell’Acqua Brian m.Cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

The Aerosol-monsoon Climate System of Asia:A New Paradigm

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Journal of meteorological Research 2016年第1期30卷 1-11页

作者： william K.m.Lau Earth Science Interdisciplinary Center University of MarylandCollege Park

This commentary is based on a series of recent lectures on aerosol-monsoon interactions I gave at the Beijing Normal University in August 2015. A main theme of the lectures is on a new paradigm of ＂An Aerosol-monsoon-Climate-System＂, which posits that aerosol, like rainfall, cloud, and wind, is an integral component of the monsoon climate system, influencing monsoon weather and climate on m1 timescales. Here, salient issues discussed in my lectures and my personal perspective regarding interactions between atmospheric dynamics and aerosols from both natural and anthropogenic sources are summarized. my hope is that under this new paradigm, we can break down traditional disciplinary barriers, advance a deeper understanding of weather and climate in monsoon regions, as well as entrain a new generation of geoscientists to strive for a sustainable future for one of the most complex and challenging human-natural climate sub-system of the earth.

关键词： aerosol monsoon climate system interaction new paradigm

Assessment of mercury(II) bioavailability using a bioluminescent bacterial biosensor: Practical and theoretical challenges

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Journal of Environmental Sciences 2010年第8期22卷 1137-1143页

作者： Paulo R G Barrocas william m Landing Robert J m Hudson Department of Sanitation and Environmental Health National School of Public Health Oswaldo Cruz Foundation Department of Oceanography Florida State University. Tallahassee Department of Natural Resources and Environmental Sciences University of Illinois

Critical methodological challenges in the microbial biosensor approach to assessing Hg（II） bioavailability were evaluated from the perspective of analytical chemists. The main challenge stems from the fact that the chemical speciation of Hg（II） in natural waters exerts a major control on its bioavailability, yet its natural complexation equilibria are extensively altered during conventional bioassays. New data, obtained using a bioluminescent Hg（II）-biosensor, that illustrate these challenges are presented and potential solutions proposed.

关键词： mercury bioavailability biosensor chemical speciation bioluminescent

Predictive value of hypo-osmotic swelling test to identifyviable non-motile sperm

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Asian Journal of Andrology 2003年第3期5卷 209-212页

作者： william m.Buckett University of Liverpool and the Reproductive medicine Unit Liverpool Women's Hospital Liverpool UK

Aim: To determine the predictive value of the hypo-osmotic swelling (HOS) test to identify viable, non-motile sperm. methods: Semen samples from 20 men with severe asthenozoospermia underwent traditional seminal analysis, eosin-nigrosin (EN) staining and the HOS test. A further EN stain was then performed on a HOS pre-treated aliquot and a total of 2000 further sperm examined. Results: The median sperm density was 5.1 million/mL (IQR 4.3-13.1) and the median motility was 3.0 % (IQR 0-7). Seven samples showed complete asthenozoospermia. Initial EN staining showed 59 % viability (range 48-69) despite the poor standard parameters and 47 % (range 33-61) in the complete asthenozoospermia subgroup. The HOS test showed 49.9 % reacted overall (range 40-59) and 41.7 % (range 22-61) in the complete asthenozoospermia subgroup. The combined HOS/EN stain showed the positive predictive value of the HOS test to identify viable sperm was 84.2 % overall and 79.7 % in the complete asthenozoospermia subgroup. Conclusion: The HOS test can effectively predict sperm viability in patients with severe and complete asthenozoospermia.

关键词： azoospermia sperm spermmotility hypo-osmotic swelling (HOS) test sperm viability predictive value

Reproductive biology of an old endemic murid rodent of Australia, the Spinifex hopping mouse, Notomys alexis:adaptations for life in the arid zone

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Integrative Zoology 2011年第4期6卷 321-333页

作者： william G.BREED Chris m.LEIGH Discipline of Anatomy and Pathology University of AdelaideAdelaideAustralia

The Spinifex hopping mouse(Notomys alexis Thomas,1922)is an arid adapted Australo–Papuan old endemic rodent that undergoes boom and bust population *** this communication,we review our findings on the timing of reproduction and the potential reproductive rate of this *** investigate the first question,the reproductive condition of adult females,and occurrence of immatures,in a population on a cattle station in central Australia was determined and,for the second,data from a laboratory colony compared to those previously published on closely related species in other *** findings show that,at least in the population at the times that monitoring was performed,reproductive activity was only taking place in spring and early summer,whereas the laboratory study indicates that females have a similar gestation length and litter size to those of most close relatives occurring in other *** have extremely small testes and store relatively few *** findings suggest that Notomys alexis might show some seasonality of reproduction at least in this region of central Australia and that this species does not have a higher reproductive rate than that of related species in other,more predictable,environments.

关键词： arid environment hopping mouse reproduction

fRAP 2.0:a community engagement method applied to cervical cancer disparities among Hispanic women

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Family medicine and Community Health 2024年第S02期12卷 44-57页

作者： Autumn m Kieber-Emmons Susan E Hansen michael Topmiller Jaskaran Grewal Carlos Roberto Jaen Benjamin F Crabtree william L miller Department of Family medicine Lehigh Valley Health NetworkAllentownPennsylvaniaUSA College of medicine USFTampaFloridaUSA Lehigh Valley Health Network AllentownPennsylvaniaUSA American Academy of Family Physicians-Health Landscape CincinattiOHUSA Lafayette College EastonPennsylvaniaUSA UT Health San Antonio San AntonioTexasUSA Rutgers Robert Wood Johnson medical School PiscatawayNew JerseyUSA Cancer Institute of New Jersey New BrunswickNew JerseyUSA

focused Rapid Assessment Process(fRAP)2.0 is a community engagement approach combining geospatial mapping with rapid qualitative assessment in cyclical fashion within communities to capture multifactorial and multilevel features impacting primary care *** 2.0 offers primary care researchers a methodology framework for exploring complex community features that impact primary healthcare delivery and *** fRAP 2.0 study design expands the fRAP from a sequential design to a cyclical process of geospatial mapping and rapid qualitative assessment in search of modifiable contextual *** participants are stakeholders from various socioecological levels whose perspectives inform study outcomes that they may use to then become the agents of change for the very problems they helped ***,we present a proof-of-concept study for fRAP 2.0 examining disparities in cervical cancer mortality rates among Hispanic women in *** primary outcomes of interest are features at the community level,medical health system level and regional government policy levels that offer opportunities for collaborative interventions to improve cervical cancer *** this study,geospatial mapping of county and ZIP code-level variables impacting postdiagnosis cervical cancer care at community,medical and policy levels were created using publicly available data and then overlaid with maps created with Texas Cancer Registry data for cervical cancer cases in three of the largest population *** disparate areas were then qualitatively explored using participant observation and ethnographic field work,alongside 39 key informant *** discussion groups and stakeholder engagement existed at every phase of the *** the fRAP 2.0 method,we created an action-oriented roadmap of next steps to improve cervical cancer care disparities in the three Texas counties with emphasis on the high disparity *** identified local change

关键词： cervical qualitative policy

Industry mix and Curvilinear Spillovers from FDI in China

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2013年第4期8卷 535-551页

作者： william m. Tracy Lally School of management and Technology Rensselaer Polytechnic Institute Troy NY 12309 USA

This paper uses industry and province specific Chinese industrial data to demonstrate a potential causal link between two strands of the FDI literature. The first strand suggests that the impact of spillovers from inward FDI is less robust in middle-income economies than in either high-income or low-income economies. The second strand suggests diminishing returns of inward FDI on horizontal labor productivity in low-technology industries but not in high-technology industries. This paper suggests a link between these two phenomena. Specifically, if both FDI intensity and industry mix vary with the level of economic development, then an industry-dependent relationship between inward FDI and horizontal spillovers could cause middle-income economies to derive fewer benefits from inward FDI than either high- or low-income economies. This paper also verifies the curvilinear relationship between FDI in low-technology industries and horizontal labor productivity without relying on problematic FDI from Hong Kong, Taiwan and macao.

关键词： foreign direct investment curvilinear China spillovers