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Do females influence paternal responsiveness in male prairie voles Microtus ochrogaster by increasing the salience of infant odors？

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Current Zoology 2013年第3期59卷 317-325页

作者： Damaris-lois LANG YAMOAH Wilhemina LARYEA Fiker FASSIL Maryam BAMSHAD Department of Natural Sciences Hostos Community College - CUNY 500 Grand Concourse Bronx NY 10451 USA Department of Biological Sciences Lehman College - The City University of New York Bronx NY 10468 USA

Male prairie voles become more responsive to infants following cohabitation with a female. Exposure to female sen- sory cues prior to offspring birth may influence male paternal tendencies by modifying his response to infant odors in particular or to odors in general. To test these hypotheses, males were housed with an unfamiliar female or a same-sex sibling for 13 days then examined for their response towards either live infants or infant-like inanimate objects covered with one of three odors： wa- ter, infant, sub-adult. We recorded the number of males that retrieved and manipulated the infants or odor-covered objects and measured the frequency and duration of time males spent attending to them or engaged in other non-social activities. Fe- male-Cohabited males approached the container holding infant-odor covered objects faster than Male-Cohabited males, but showed no differences in time spent manipulating those objects. Males in both groups spent more time manipulating live infants than odor-covered objects. However, Female-Cohabited subjects were more likely to manipulate odor-covered objects as well as live infants than Male-Cohabited subjects. Additionally, the frequency of self-grooming in Female-Cohabited males was higher for water-covered objects compared to Male-Cohabited males. In presence of water and live infants, Female-Cohabited males groomed themselves with greater frequency than in presence of infant odor or sub-adult odor. The data suggest that female cues increase the male＇s sensitivity to infant odors and enhance the salience of non-social odors.

关键词： Biparental Social cognition Social attention Social odors Odor perception Sensory perception

Identifying the ground state structures of point defects in solids

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npj Computational Materials 2023年第1期9卷 2095-2105页

作者： Irea Mosquera-lois Seán R.Kavanagh Aron Walsh David O.Scanlon Thomas Young Centre and Department of Chemistry University College London20 Gordon StreetLondon WC1H 0AJUK Thomas Young Centre and Department of Materials Imperial College LondonExhibition RoadLondon SW72AZUK

Point defects are a universal feature of *** identification is addressed by combining experimental measurements with theoretical *** standard modelling approach is,however,prone to missing the ground state atomic configurations associated with energy-lowering reconstructions from the idealised crystallographic *** ground states compromise the accuracy of calculated *** address this issue,we report an approach to navigate the defect configurational landscape using targeted bond distortions and *** of our workflow to eight materials(CdTe,GaAs,Sb_(2)S_(3),Sb_(2)Se_(3),CeO_(2),In_(2)O_(3),ZnO,anatase-TiO_(2))reveals symmetry breaking in each host crystal that is not found via conventional local minimisation *** point defect distortions are classified by the associated physico-chemical *** demonstrate the impact of these defect distortions on derived properties,including formation energies,concentrations and charge transition *** work presents a step forward for quantitative modelling of imperfect solids.

关键词： ground distortion solids

Accounting desk book : the accountant's everyday instant answer book / lois Ruffner Plank ……［et al.］

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Medical Nutritional Therapy for Pre-gestational and Gestational Diabetes Mellitus

2009年

作者： lois Ruffner Plank ……［et al.］

来源：畅想之星图书光盘版（南... 评论

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Journal of Health Science 2018年第2期6卷 79-90页

作者： lois Jovanovic Keck University Medical School Los Angeles California USA University of Southern California Santa Barbara 93109 California USA

Pregnancy causes a multitude of metabolic changes within a woman’s body in order to provide the proper nutrients to the developing fetus. In women with diabetes type 1, type 2, and GDM （gestational diabetes mellitus） these metabolic perturbations must be treated distinctly and aggressively to optimize fetal development and health. Pre-gestational diabetes （either type 1 or type 2） has the potential to subject the developing fetus to abnormal maternal glucose levels resulting in problems with organogenesis producing congenital abnormalities or spontaneous abortion. Furthermore, gestational diabetes mellitus presents after organogenesis in the second part of pregnancy, therefore the major risk for the fetus is macrosomia. Although the goal for dietary therapy for each of these disorders is the same which is euglycaemia, the means to achieve it are very different and somewhat controversial. In the case of gestational diabetes, the main stay of therapy is medical nutritional therapy whereas in insulin requiring diabetes, dietary therapy is compensated with pre-meal insulin injections. The metabolic changes in normal pregnancy will be presented followed by the general guidelines for pregnancy. Fetal complications associated with inadequate nutrition or metabolic perturbation will be briefly explored, followed by issues and treatment for gestational diabetes mellitus, with emphasis on specific dietary therapies for GDM.

关键词： Glucose control peak post prandial glucose concentration macrosomnia pregnancy glucose mediated complications of pregnancy.

电化学排除钢筋混凝土结构氯盐污染的试验研究

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中国公路学报 2003年第3期16卷 44-47页

作者：干伟忠王纪跃 BOES A lois 宁波高等专科学校建筑工程系浙江宁波315016 宁波市城市建设设计研究院浙江宁波315010 亚琛应用科技大学土木工程系北威州亚琛52066

针对实际混凝土结构工程,设计了用电化学方法排除氯盐污染的实验室试验;分析了电化学排除氯盐污染的影响因素;提出了实际工程中脱盐技术参数的确定方法以及无损评价方法。

关键词：桥梁工程混凝土结构试验研究氯盐污染除盐电化学

Diversification of SUMO-Activating Enzyme in Arabidopsis： Implications in SUMO Conjugation

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Molecular Plant 2013年第5期6卷 1646-1660页

作者： Laura Castano-Miquel Josep Segui Silvia Manrique Ines Teixeira Lorenzo Carretero-Paulet Felix Atencio L. Maria lois Center for Research in Agricultural Genomics CRAG (CSIC-IRTA-UAB-UB) Edifici CRAG-Campus UAB Bellaterra (Cerdanyola del Valles) 08193 Barcelona Spain Department of Biological Sciences SUNY-University at Buffalo North Campus 109 Cooke Hall Buffalo NY 14260 USA

Sumoylation is an essential posttranslational modification that participates in many biological processes including stress responses. However, little is known about the mechanisms that control Small Ubiquitin-like MOdifier （SUMO） conjugation in vivo. We have evaluated the regulatory role of the heterodimeric E1 activating enzyme, which catalyzes the first step in SUMO conjugation. We have established that the E1 large SAE2 and small SAE1 subunits are encoded by one and three genes, respectively, in the Arabidopsis genome. The three paralogs genes SAEla, SAElbl, and SAElb2 are the result of two independent duplication events. Since SAElbl and SAElb2 correspond to two identical cop- ies, only two E1 small subunit isoforms are present in vivo： SAEla and SAElb. The E1 heterodimer nuclear localization is modulated by the C-terminal tail of the SAE2 subunit. In vitro, SUMO conjugation rate is dependent on the SAE1 isoform contained in the E1 holoenzyme and our results suggest that downstream steps to SUMO-E1 thioester bond formation are affected. In vivo, SAEla isoform deletion in T-DNA insertion mutant plants conferred sumoylation defects upon abi- otic stress, consistent with a sumoylation defective phenotype. Our results support previous data pointing to a regula- tory role of the E1 activating enzyme during SUMO conjugation and provide a novel mechanism to control sumoylation in vivo by diversification of the E1 small subunit.

关键词： E1 activating enzyme conjugation rate subcellular localization regulation abiotic stress gene duplication.

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EMILY

英语学习 1994年第12期 11-18页

作者： lois Simmie 方玉

Every year we rented the same cottage at the west end of thelake. All through the dry, cold winter, when snow lay thick onthe town, I dreamed about the lake; and in the summer, too,when parched prairie grass crackled ... 详细信息

关键词： EMILY

Relationship between acute hypercarbia and hyperkalaemia during surgery

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World Journal of Clinical Cases 2019年第22期7卷 3711-3717页

作者： Laurence Weinberg Amelia Russell lois Mackley Charles Dunnachie Joshua Meyerov Chong Tan Michael Li Raymond Hu Dharshi Karalapillai Department of Anaesthesia Austin HealthMelbourneVictoria 3084Australia Department of Intensive Care Austin HealthMelbourneVictoria 3084Australia Melbourne Medical School University of MelbourneVictoria 3010Australia

BACKGROUND The relationship between hyperkalaemia and metabolic acidosis is well described in the critical care setting;however,the relationship between acute respiratory acidosis and plasma potassium concentration is less well *** a controlled model of increasing levels of hypercarbia,we tested the hypothesis of whether increasing levels of hypercarbia are associated with changes in plasma potassium *** To determine whether increasing levels of hypercarbia are associated with changes in plasma potassium *** We performed a post-hoc study examining changes in serum potassium in 24 patients who received increased levels of hypercarbia during cardiac *** blood gases and plasma concentrations of potassium were measured at baseline,3 min prior to,and then every 3 min for 15 min during the intervention of *** primary endpoint was the absolute change in serum K+at 15 min compared to the baseline K+*** following secondary endpoints were evaluated:(1)The association between CO2 and serum K+concentration;and(2)The correlation between plasma pH and serum K+*** During the intervention,PaCO2 increased from 43.6 mmHg(95%CI:40.1 to 47.1)at pre-intervention to 83.9 mmHg(95%CI:78.0 to 89.8)at 15 min after intervention;P<*** mean(SD)serum potassium increased from 4.16(0.35)mmol/L at baseline to 4.28(0.33)mmol/L at 15 min(effect size 0.09 mol/L;P=0.22).There was no significant correlation between PaCO2 and potassium(Pearson’s coefficient 0.06;95%CI:-0.09 to 0.21)or between pH and potassium(Pearson’s coefficient-0.07;95%CI:-0.22 to 0.09).CONCLUSION Acute hypercarbia and subsequent respiratory acidaemia were not associated with hyperkalaemia in patients undergoing major surgery.

关键词： Anaesthesia Intensive care Biochemistry Surgery

Persistence of Dioxin TCDD in Southern Vietnam Soil and Water Environments and Maternal Exposure Pathways with Potential Consequences on Congenital Heart Disease Prevalence in Vietnam

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Open Journal of Soil Science 2022年第4期12卷 119-150页

作者： lois Wright Morton Casey Culbertson College of Agriculture and Life Sciences Iowa State University Ames IA USA MD1World San Diego CA USA

Waterlogged soils and submerged sediments in wetlands and agricultural lands used for rice paddies and aquaculture have anaerobic conditions that slow and prevent the photo and microbial degradation of dioxin TCDD (2,3,7,8-tetracholorodibenzo-p-dioxin), enabling it to persist in environments for long periods. Over 1.6 million ha of land in southern Vietnam were sprayed with 2,4,5-T herbicides (e.g. Agent Orange) contaminated with dioxin TCDD during the Vietnam War (1961-1971);45% of these ha received four or more spray flight missions. Dioxins are endocrine disrupters and may induce cardiovascular disease, growth, and developmental defects, diabetes, hormonal dysfunctions and disruptions, certain cancers, and chloracne. Outpatient screening clinic 2020 data on Vietnamese children suspected of congenital heart disease (CHD) showed the childhood CHD prevalence rate in Vietnam of 13.356/1000, significantly elevated compared to the Asian CHD prevalence rate of 3.531/1000. CHD prevalence rate differences between North Vietnam (2.541/1000) and south of the 17th parallel (10.809/1000) were significant. Vietnamese farmers, especially pregnant women whose occupations involve daily contact with soil and sediments where dioxin TCDD persists in the environment may be at risk of dioxin accumulation from dermal exposure and bioaccumulation via diet. There is an urgent need for funded longitudinal genetic and clinical studies to assess CHD and other organ system childhood malformations due to in utero TCDD exposure. We recommend an integrated research design involving 1) site-specific locations that received high volumes and multiple spray loads of herbicides during the Vietnam War;2) soil sampling of submerged and waterlogged soils and sediments where TCDD may not have degraded;3) production areas of agriculture, fisheries, and other aquatic products;4) risk assessment dioxin levels in foods where TCDD is likely to bioaccumulate;5) child-bearing age and pregnant women

关键词： Agent Orange 2 4 5-T Herbicides Dioxin TCDD Vietnam Soils and Sediments Congenital Heart Disease (CHD) Birth Prevalence Saturated and Submerged Soils Rice Paddies Aquaculture Rural Livelihoods Bioaccumulation