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艺术村

英语学习 2015年第3期 64-66页

作者：于琰 william logan

曾有过一座艺术村，在那里各幅名画纷纷写下自己的回忆录。《蒙娜丽莎》已经奋笔疾书了一个多世纪，只是为全面地展现达·芬奇的璀璨一生。每当被人问起，她就挤出那个恼人的笑容。

关键词：艺术《蒙娜丽莎》回忆录

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Gladiator

Neuroprotection by resveratrol-glucuronide and quercetin-glucuronide via binding to polyphenol-and glycosaminoglycan-binding sites in the laminin receptor

2001年

作者： Annette Keen Dewey Gram David Franzoni John logan and william Nicholson.

来源：畅想之星图书光盘版（南... 评论

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Neural Regeneration Research 2025年第3期20卷 819-820页

作者： Rayudu Gopalakrishna Jennifer Aguilar Emily Lee william J.Mack Department of Integrative Anatomical Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ... 详细信息

关键词： resveratrol molar dated

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： william J.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

Colossal negative magnetoresistance from hopping in insulating ferromagnetic semiconductors

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Journal of Semiconductors 2022年第11期43卷 44-53页

作者： Xinyu Liu logan Riney Josue Guerra william Powers Jiashu Wang Jacek K.Furdyna Badih A.Assaf Department of Physics and Astronomy University of Notre DameNotre DameIN 46556USA

Ferromagnetic semiconductor Ga_(1–x)Mn_(x)As_(1–y)P_(y) thin films go through a metal–insulator transition at low temperature where electrical conduction becomes driven by hopping of charge *** this regime,we report a colossal negative magnetoresistance(CNMR)coexisting with a saturated magnetic moment,unlike in the traditional magnetic semiconductor Ga_(1–x)Mn_(x)*** analyzing the temperature dependence of the resistivity at fixed magnetic field,we demonstrate that the CNMR can be consistently described by the field dependence of the localization length,which relates to a field dependent mobility *** dependence is likely due to the random environment of Mn atoms in Ga_(1-x)Mn_(x)As_(1-y)P_(y) which causes a random spatial distribution of the mobility that is suppressed by an increasing magnetic field.

关键词： ferromagnetic semiconductor colossal negative magnetoresistance variable-range hopping nearest-neighbor hopping Anderson localization spintronic

Pseudogenization of the Humanin gene is common in the mitochondrial DNA of many vertebrates

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Zoological Research 2017年第4期38卷 198-202页

作者： lan S. logan 22 Parkside Drive Exmouth Devon UK

In the human the peptide Humanin is produced from the small Humanin gene which is embedded as a gene-within-a-gene in the 16S ribosomal molecule of the mitochondrial DNA （mtDNA）. The peptide itself appears to be significant in the prevention of cell death in many tissues and improve cognition in animal models. By using simple data mining techniques, it is possible to show that 99.4% of the human Humanin sequences in the GenBank database are unaffected by mutations. However, in other vertebrates, pseudogenization of the Humanin gene is a common feature; occurring apparently randomly in some species and not others. The persistence, or loss, of a functional Humanin gene may be an important factor in laboratory animals, especially if they are being used as animal models in studies of Alzheimer＇s disease （AD）. The exact reason why Humanin underwent pseudogenization in some vertebrate species during their evolution remains to be determined. This study was originally planned to review the available information about Humanin and it was a surprise to be able to show that pseudogenization has occurred in a gene in the mtDNA and is not restricted solely to chromosomal genes.

关键词： mtDNA Humanin Pseudogenization NUMT

Resilience:Lessons to be learned from safety and acceptable risk

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Journal of Safety Science and Resilience 2021年第4期2卷 253-257页

作者： Kosovac Anna Tom McLeod logan Faculty of Engineering and Information Technology The University of MelbourneAustralia Civil and Natural Resources Engineering The University of CanterburyNew Zealand

It is not unusual to see the concept of resilience housed in binary terms:Your city is either‘resilient’or *** contrast,being‘safe’is widely recognized as a statement based on‘acceptable risk’where absolute safety is *** why do we treat resilience and,as an example,the idea of“Resilient Cities”as a distinct endpoint?In this paper,we argue that this mindset is not only incongruent with current understandings of safety and risk but could create a false sense of security for systems that otherwise have been judged‘resilient’.An alternative is that we can and should consider framing resilience in the same manner as we do to *** benefit of doing this is that we can learn from the safety literature and appreciate that,like for safety,there is no such thing as absolute ***,we should be striving to constantly identify and reduce the risks to our systems and society.

关键词： Risk analysis Safety Risk assessment Resilient Resilience Urban Cities Disaster management

Amalgamated gold-nanoalloys with enhanced catalytic activity for the detection of mercury ions(Hg^2+)in seawater samples

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Nano Research 2020年第4期13卷 989-998页

作者： Natasha logan Claire McVey Christopher Elliott Cuong Cao Institute for Global Food Security School of Biological SciencesQueens University Belfast19 Chlorine GardensBelfastBT95DLUK Material and Advanced Technologies for Healthcare Queens University Belfast18-30 Malone RoadBelfastBT95BNUK

Mercury(Hg)is extremely toxic,and continues to cause major threats to aquatic life,human health and the ***^2+mainly derives from seawater as a product of atmospheric deposition,therefore there is great demand for sensing approaches that can detect Hg^2+in seawater ***,we demonstrate that the peroxidase-mimicking activity of gold nanoparticles(AuNPs)or so-called nanozymes,can be exploited for the detection of Hg^2+ions in various water *** a high electrolyte environment,the catalytic activity for the oxidation of 3,3’,5,5’-tetramethylbenzidine(TMB)was significantly diminished due to poor stability of the *** activity was reduced by-73.7%when the NaCl concentration was higher than 1.168%,which is much lower than that of seawater(-3.5%),thus presenting its unsuitability for detecting Hg^2+in harsh water *** overcome this limitation,AuNPs were first functionalized with oligo-ethylene glycol(OEG),of which their colloidal form presented high stability in NaCl concentrations up to 20%and across a wide range of pHs from ***,the catalytic activity of OEG-AuNPs for the oxidation of TMB was strongly suppressed by the coating,but enhanced upon formation of Au-Hg *** novel finding underlies a straightforward,sensitive,and highly selective detection platform for Hg^2+in water *** approach could detect the exposure limit level for Hg^2+in drinking water(i.e.,2 ppb for tap and bottled water)as set by the United States Environmental Protection Agency(EPA)and the World Health Organization(WHO).When Hg^2+was spiked into a 3.5%saline solution and a coastal seawater certified reference material(CRM),the detection limits were found to be 10 ancM 3 ppb,respectively,which exceed the Hg^2+concentrations commonly found within seawater(-60-80 ppb).The whole procedure takes less than 45 min to conduct,providing a highly innovative,rapid and low-cost approach for detecting Hg^2+in complex water matrices.

关键词： gold nanoparticles nanozyme peroxidase-like mercury detection w ater samples seawater

Your personal choices in transportation and food are important for lowering carbon emissions

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Frontiers of Environmental Science & Engineering 2024年第6期18卷 27-32页

作者： Bruce logan Fang Zhang Wulin Yang Le Shi Institute of Energy and the Environment The Pennsylvania State UniversityUniversity ParkPA 16802USA School of Environment Tsinghua UniversityBeijing 100084China College of Environmental Sciences and Engineering Peking UniversityBeijing 100871China College of Environmental and Resource Sciences Zhejiang UniversityHangzhou 310058China

There is a global need to reduce greenhouse gas emissions to limit the extent of climate change.A better understanding of how our own activities and lifestyle influence our energy use and carbon emissions can help us enable changes in activities that can lead to reductions in carbon *** we discuss an approach based on examining carbon emissions from the perspective of the unit C,where 1 C is the CO_(2)from food a person would on average eat every *** approach shows that total CO_(2)emissions in China,normalized by the population,is 22.5 C while carbon emissions for a person in the US is 43.9 C.A better appreciation of our own energy use can be obtained by calculating carbon emissions from our own activities in units of C,for example for driving a car gasoline or electric vehicle a certain number of kilometers,using electricity for our homes,and eating different *** this information,we can see how our carbon emissions compare to national averages in different countries and make decisions that could lower our personal CO_(2)emissions.

关键词： Carbon dioxide Climate change Daily energy Greenhouse gas