检索结果-南通市图书馆

Journal of Integrative Agriculture 2014年第2期13卷 455-466页

作者： william b lacy Leland L Glenna Dina biscotti Rick Welsh Kate Clancy University of California State College Pennsylvania State University Syracuse University Johns Hopkins University

Partnerships between U.S. universities and industries have existed for several decades and in recent years have become generally more varied, wider in scope, more aggressive and experimental and higher in public visibility. In addition, in the last few decades, public and private interests have advocated for government policies and laws to globally promote the commercialization of university science. This paper examines the persistence or convergence of the two cultures of science and the implications of this commercialization for university-industry relationships in agriculture biotechnology. The perceptions and values of over 200 U.S. university and industry scientists, managers and administrators who participate in or oversee research collaborations in agricultural biotechnology were analyzed. The findings revealed that the participants in these research relationships continue to perceive very distinct cultures of science and identify a wide range of concerns and disadvantages of these partnerships. Several actions were discussed to ensure that the two cultures serve complementary roles and that they maximize the public benefits from these increasing collaborations.

关键词： two cultures of science agricultural biotechnology university-industry relationships

Optimal diet strategy of a large-bodied psittacine: food resource abundance and nutritional content enable facultative dietary specialization by the Military Macaw

在线全文

学校读者我要写书评

暂无评论

Avian Research 2019年第4期10卷 469-477页

作者： Sylvia Margarita de la Parra‑Martinez Luis Guillermo Munoz‑lacy Alejandro Salinas‑Melgoza Katherine Renton Departamento de Ciencias biologicas Centro Universitario de la CostaUniversidad de GuadalajaraAv.Universidad No.203Delegacion IxtapaC.P.48280 Puerto VallartaJaliscoMexico Comision Nacional Para el Conocimiento y Uso para la biodiversidad Liga Periferico‑Insurgentes Sur 4903Delegacion Tlalpan14010 Mexico CityMexico Facultad de biologia Universidad Michoacana de San Nicolas de HidalgoCiudad UniversitariaMoreliaMichoacanMexico Estacion de biologia Chamela Instituto de BiologiaUniversidad Nacional Autonoma de MexicoApartado Postal 21San Patricio‑MelaqueJaliscoMexico

background:Dietary specialization should arise when there is a relatively high abundance of a particular resource,where animals may select food items to obtain an optimal diet that maximizes energy ***‑bodied psittacines frequently exhibit a narrow dietary niche with specific habitat use,but few studies have determined whether psittacines select food resources,and how this influences habitat ***:We established fruiting phenology transects to evaluate food resource availability for the large‑bodied Military Macaw(Ara militaris)in semi‑deciduous,deciduous,and pine‑oak forest at two sites along the coast of Jalisco,during the dry season when macaws are *** also determined Military Macaw diet by observations of foraging macaws along transect routes,and conducted bromatological analysis of the nutritional content of the most consumed ***:Military Macaws used six plant species as food items during the dry season,and had a narrow dietary niche(Levins’b=0.28),with 56%of foraging macaws consuming the seeds of Hura *** food resources were recorded in pine‑oak forest during the dry season,with food resources and foraging by macaws concentrated in tropical deciduous and semi‑deciduous forest,where *** was the most abundant fruiting tree *** considering the proportional availability of food resources,we determined a broad Hurlbert dietary niche breadth of H=0.67,indicating that Military Macaws consumed food resources according to their ***,the seeds of *** were an important source of protein,carbohydrates,minerals and moisture,and the hard fruitcasing means that these seeds are exclusively available for ***:by concentrating their diet on the most abundant resources,Military Macaws may increase foraging efficiency in the dry *** high nutrient content also means that concentrating the diet on seeds of *** may be an optimal foraging strategy for Military Macaws

关键词： Ara militaris bromatological analysis Diet composition Food resource selection Fruiting phenology Hura

食管测压和pH监测:胃肠病专家所坚持的公开准则

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 44-45页

作者： Ali M.A. lacy b.E. 郑世成 Division of Gastroenterology and Hepatology Dartmouth-Hitchcock-Medical Center 1 Medical Center Drive Lebanon NH 03756 United States Dr.

Goals: To determine whether gastroenterologists use esophageal manometry (EM) and esophageal pH recording (pHR) in accordance with published guidelines. Study: Questionnaires were mailed to 900 randomly selected gastroenterologists nationwide. Each questionnaire requested demographic information and contained 11 case scenario-based questions, followed by a choice of management options. Results: A total of 275 completed questionnaires (30.6% )were returned. 63.6% and 64.4% of respondents were aware of published guidelines regarding the use of EM and pHR, respectively. The majority of respondents ordered EM appropriately: 1) to confirm a suspected diagnosis of achalasia (97.1% ); 2) to establish a diagnosis of connective tissue disease (89.7% ); 3) as part of the preoperative evaluation for anti-reflux surgery (74.6% ); and 4) to ensure the proper placement of pH probes (69.4% ). EM was rarely ordered for the initial workup of noncardiac chest pain. The majority of responding gastroenterologists would order pHR for the evaluation of: 1) endoscopy-negative patients being considered for anti-reflux surgery (79.1% ); 2) patients with recurrent GERD symptoms after anti-reflux surgery (62.5% ); 3) endoscopy-negative patients with GERD symptoms refractory to proton pump inhibitor (PPI) therapy; and 4) patients with extraesophageal manifestations of GERD that are refractory to PPI therapy (88.7% ). Conclusions: The majority of gastroenterologists in our study order EM and pHR in accordance with published guidelines. However, EM appears to be used less than expected for preoperative evaluation before anti-reflux surgery and for ensuring the proper placement of pH probes. In addition, the use of pHR to evaluate persistent GERD symptoms after anti-reflux surgery was less than anticipated.

关键词：食管测压 pH监测胃肠病失弛缓症抗反流手术内镜检查结缔组织病胸痛应用情景阴性患者

经肛全直肠系膜切除术与前入路(经腹)全直肠系膜切除术治疗直肠癌:一项在西班牙加泰罗尼亚地区进行的基于人群的倾向性评分匹配研究

在线全文

学校读者我要写书评

暂无评论

结直肠肛门外科 2021年第6期27卷 610-612页

作者：卓长华池畔 MANCHON-WALSH P DE lacy F b PERA M 福建省肿瘤医院胃肠肿瘤外科福建福州350014 福建医科大学附属协和医院普通外科(结直肠外科) 福建福州350001 不详

背景:经肛全直肠系膜切除术的临床应用价值尚存在争议。目的:比较经肛与前入路(经腹)全直肠系膜切除术治疗直肠癌的短期和中期效果。设计:这是一项多中心的回顾性队列研究。设置:该研究包括加泰罗尼亚地区所有的公立医院。患者:2015—2... 详细信息

背景:经肛全直肠系膜切除术的临床应用价值尚存在争议。目的:比较经肛与前入路(经腹)全直肠系膜切除术治疗直肠癌的短期和中期效果。设计:这是一项多中心的回顾性队列研究。设置:该研究包括加泰罗尼亚地区所有的公立医院。患者:2015—2016年接受经肛或前入路全直肠系膜切除术(开腹或腹腔镜)治疗的所有原发性非转移性直肠癌患者。主要结局指标:生存状态数据收集至2019年3月。

关键词：全直肠系膜切除术前入路回顾性队列研究中期效果结局指标公立医院直肠癌患者数据收集

与肠功能失调相关的肛门失禁亚型:临床、生理及社会心理方面的特征

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2005年第4期1卷 19-20页

作者： Crowell M.D. lacy b.E. Schettler V.A. 樊菁 Gastrointest. Physiol. and Motility Div. of Gastroenterol. and Hepatol. Mayo Clinic Scottsdale 13400 E. Shea Blvd. Scottsdale AZ 85259 United StatesDr.

bACKGROUND: We hypothesized that functional anal incontinence with no structur al explanation comprises distinct pathophysiologic subgroups that could be ident ified on the basis of the predominant presenting bowel pattern. METHODS: Consecu tive patients (n = 80) were prospectively grouped by bowel symptoms as 1) incont inence only, 2) incontinence +constipation, 3) incontinence +diarrhea, and 4) incontinence +alternating bowel symptoms. The Hopkins bowel Symptom Questionnai re, the Symptom Checklist 90-R, and anorectal manometry were completed. RESULTS : Significant group differences were found between subcategories of incontinent patients on the basis of symptoms. Abdominal pain was more frequent in patients with altered bowel patterns. Patients with alternating symptoms reported the hig hest prevalence of abdominal pain, rectal pain, and bloating. basal anal pressur es were significantly higher in alternating patients (P = 0.03). Contractile pre ssures in the distal anal canal were diminished in the incontinent only and dia rrhea groups (P = 0.004). Constipated patients with incontinence exhibited eleva ted thresholds for the urge to defecate (P = 0.027). Dyssynergia was significant ly more frequent in patients with incontinence and constipation or alternating b owel patterns. CONCLUSIONS: Distinct patterns of pelvic floor dysfunction were i dentified in patient subgroups with anal incontinence, based on the presence or absence of altered bowel patterns. Physiologic assessments suggested different p athophysiologic mechanisms among the subgroups. The evaluation of patients with fecal incontinence should consider altered bowel function.

关键词：肛门失禁功能失调肠道症状社会心理肛门直肠测压交替性便时盆底功能直肠痛腹胀症状

短期事件对旅游的影响:以中国SARS危机为例

在线全文

学校读者我要写书评

暂无评论

桂林旅游高等专科学校学报 2005年第2期16卷 30-39页

作者：曾本祥 R. W. (bill)Carter T. De lacy 昆士兰大学资源与乡村管理学院澳大利亚可持续旅游研究中心

通过回顾近年来世界各国发生的短期危机对旅游产生的影响,重点分析2003年的SARS疫情给中国经济特别是旅游业造成的重大损失,讨论了不同的短期危机对旅游的不同影响以及旅游在危机后的不同恢复时间。旅游业对短期危机缺乏足够的防御能力... 详细信息

通过回顾近年来世界各国发生的短期危机对旅游产生的影响,重点分析2003年的SARS疫情给中国经济特别是旅游业造成的重大损失,讨论了不同的短期危机对旅游的不同影响以及旅游在危机后的不同恢复时间。旅游业对短期危机缺乏足够的防御能力,但通常能较为迅速的走上复苏之路。在这个过程中,适当的危机管理措施和有效的恢复策略是十分重要和不可或缺的。

关键词： SARS危机短期事件 SARS疫情 2003年重大损失中国经济重点分析恢复时间防御能力不可或缺管理措施旅游业各国回顾复苏

弥漫大b细胞淋巴瘤靶向测序、分子亚型和预后:英国血液肿瘤研究网报告

在线全文

学校读者我要写书评

暂无评论

中华医学杂志 2021年第13期101卷 969-969页

作者： lacy SE barrans SL beer PA 刘怡君(编译) 不详河北燕达陆道培医院检验科分子医学室

弥漫大b细胞淋巴瘤(DLbCL)是一种最常见的非霍奇金淋巴瘤,具有显著的临床预后差异和分子异质性。近年来有多项基于基因表达谱和外显子组研究的数据提出了多种不同的DLbCL分子分型建议,越来越显示出基于基因指标的精确分型对DLbCL的诊疗... 详细信息

弥漫大b细胞淋巴瘤(DLbCL)是一种最常见的非霍奇金淋巴瘤,具有显著的临床预后差异和分子异质性。近年来有多项基于基因表达谱和外显子组研究的数据提出了多种不同的DLbCL分子分型建议,越来越显示出基于基因指标的精确分型对DLbCL的诊疗指导意义,但目前尚未达成专家一致认可并且易于实施的分型标准。为了建立一套更系统并且易于临床实施的分子外型体系,英国血液肿瘤研究网报道了一项基于人群的患者队列研究。该项目对来自14家医院涵盖了400万英国人口、具有完整随访资料的928例DLbCL患者的肿瘤DNA样本进行了293个血液肿瘤相关基因的靶向测序研究。

关键词：弥漫大b细胞淋巴瘤非霍奇金淋巴瘤分子亚型肿瘤相关基因血液肿瘤分子异质性队列研究基因表达谱

建立一个窄带成像分型以减少胃息肉的常规活检

在线全文

学校读者我要写书评

暂无评论

Gastroenterology Report 2021年第3期9卷 219-225,I0002页

作者： Ivor b.Asztalos Caitlin A.Colling Anna M.buchner Vinay Chandrasekhara Department of Pediatrics Children’s Hospital of PhiladelphiaPhiladelphiaPAUSA Department of Internal Medicine Massachusetts General HospitalBostonMAUSA Division of Gastroenterology and Hepatology Hospital of the University of PennsylvaniaPhiladelphiaPAUSA Division of Gastroenterology and Hepatology Mayo ClinicRochesterMNUSA

背景:上消化道内镜检查时意外发现的胃息肉大多都是低风险的,但目前的指南推荐对所有的胃息肉都进行活检以进行组织病理学分析。我们设计了一个简单的窄带成像(NbI)分型,旨在减少对低危胃息肉的常规活检。方法:筛选出具有组织病理学诊断... 详细信息

背景:上消化道内镜检查时意外发现的胃息肉大多都是低风险的,但目前的指南推荐对所有的胃息肉都进行活检以进行组织病理学分析。我们设计了一个简单的窄带成像(NbI)分型,旨在减少对低危胃息肉的常规活检。方法:筛选出具有组织病理学诊断的73枚息肉,提取其NbI影像和白光影像,进行诊断性队列研究。两名并不清楚息肉性质的内镜医生对每枚息肉的NbI特征进行独立评估,包括颜色、血管模式和表面结构,并将这些特征进行各种组合,从而建立一个分型标准,以鉴别低危息肉(基底腺性或增生性息肉)与高危息肉(腺瘤或腺癌)以及基底腺性息肉(FGP)和非FGP。结果:孤立网状的血管模式和均质或缺失的表面结构可有效鉴别低危与高危胃息肉。将这两个特征相结合来诊断高危息肉,可获得100%的阴性预测值(95%CI:100%-100%),阳性预测值为13.7%(95%CI:2.6%-24.8%),灵敏度和特异度分别为100%(95%CI:100%-100%)和53.7%(95%CI:45.3%-62.0%);可将需要活检的息肉数量减少50%的同时,不会漏掉一例高危息肉。采用孤立网状的血管模式来判断无需活检的FGP,其阴性预测值高达94.9%(95%CI:89.2%-100%),阳性预测值为63.2%(95%CI:47.2%-79.2%),灵敏度和特异度分别为94.8%(95%CI:89.5%-100%)和63.6%(95%CI:51.3%-76.0%)。结论:这项推导性队列研究发现,NbI有助于高危与低危胃息肉的鉴别,从而对减少低危息肉的常规活检。这些结果需要在不同的研究人群中进行验证。

关键词：胃息肉常规活检增生性息肉窄带成像腺性阴性预测值阳性预测值队列研究