检索结果-南通市图书馆

Em.racing substrate m.ltispecificity in plant ABC transporters

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

m.lecular Plant 2024年第7期17卷 990-992页

作者： m.rkus m.Geisler Departm.nt of Biology University of Fribourg1700 FribourgSwitzerland

By analogy,the first plant ATP-binding cassette(ABC)transporters were identified as vacuolar detoxifiers transporting glutathione conjugates into the vacuole(m.rtinoia et al.,1993).This som.what negative im.ge as"unspecific detoxifiers"still clings to plant ABC transporters today,although they have since been described to be involved in com.letely different program.,including developm.nt and defense(Park et al.,2017).In this context,som. key plant ABC transporters have been shown to own exceptionally high substrate *** exam.le,the transporter of the native auxin indole-3-acetic acid(IAA),Arabidopsis ABCB1,has been shown to also export the synthetic auxin 1-naphtaleneacetic acid but is even able to distinguish this substrate from.its structural isom.r,2-naphtaleneacetic acid(Geisler et al.,2005).Likewise,ABCG36 and ABCG37,which are known to have a broader substrate portfolio(Park et al.,2017;Aryal et al.,2023),export IBA but do not touch IAA(Aryal et al.,2023).Recently,several reports have challenged our current view on the reported high substrate specificity of plant ABCs,which requires clarification.

关键词： specificity analogy exceptional

人Fcr受体Ⅱ:一种由蛋白水解作用活化的备用受体吗?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国外医学（免疫学分册） 1991年第5期14卷 262-265页

作者： wil J.m.Tax 王大坤

在各种免疫防御机制中,IgGFc 受体(FcrR)起着重要作用,其中包括对免疫复合物的吞饮、对抗体包被颗粒的吞噬。此外,FcrR 还控制几种炎性介质的释放。近年,应用不同FcrR 的单克隆抗体在鉴定这些受体和确定其特性方面已取得了很大进展。有... 详细信息

在各种免疫防御机制中,IgGFc 受体(FcrR)起着重要作用,其中包括对免疫复合物的吞饮、对抗体包被颗粒的吞噬。此外,FcrR 还控制几种炎性介质的释放。近年,应用不同FcrR 的单克隆抗体在鉴定这些受体和确定其特性方面已取得了很大进展。有三类人FcrR[FcrR1(CD_(64)),FcrRⅡ(CD_(32))和FcrRⅢ(CD_(16))]已从蛋白分子和互补DNA(cDNA)水平上得到确定。人FcrR 的表达和亲合力三类Fcr 受体在类型不同细胞上表达不同,FcrRⅠ持续地表达在人单核细胞和巨噬细胞上。γ干扰素(IFN-γ)

关键词：受体 IgGFc受体表达亲和力

Progression of lesions in the respiratory tract of broilers after single infection with Escherichia coli com.ared to superinfection with *** after infection with infectious bronchitis virus

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Progression of lesions in the respiratory tract of broilers ...

荧光变异能够替代镜质体反射率作为石油勘探中测定热成熟度的一种…

The 15th World Veterinary Poultry Congress

作者： R.m.rius Dwars m.eke G.R.m.tthijs wil J.m.Landm.n Lonneke Vervelde Departm.nt of Farm.Anim.l Health Faculty of Veterinary MedicineUtrecht UniversityPO Box 801513508 TD Utrechtthe Netherlands Departm.nt of Farm.Anim.l Health Faculty of Veterinary MedicineUtrecht UniversityPO Box 801513508 TD Utrechtthe Netherlands Anim.l Health Service（GD） Poultry Health Centre Ltd.Deventerthe Netherlands. Departm.nt of Infectious Diseases and Im.unology Faculty of Veterinary MedicineUtrecht UniversityUtrechtthe Netherlands

＜正＞Descriptions of the pathology of colibacillosis in broilers m.stly concern a m.xed infection of both a virus and Escherichia *** we describe the progression of *** lesions of the respiratory tract with tim. in- duced after a single *** infection and those produced by an infection with *** preceded by an Infec-

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

海上油气译丛 1995年第3期 24-45页

作者： wil.,RWT 姚文江

多煤组份荧光变异（ＦＡＭＭ）技术与镜质体反射率密切相关。直到目前，沉积岩中分散有机质（ＤＯＭ）的荧光变异研究被认为还存在着许多技术上的难题。随着光学显微探针的引进，配以小型连续波的气体激光发射稳定的兰色射线，聚焦到样... 详细信息

多煤组份荧光变异（ＦＡＭＭ）技术与镜质体反射率密切相关。直到目前，沉积岩中分散有机质（ＤＯＭ）的荧光变异研究被认为还存在着许多技术上的难题。随着光学显微探针的引进，配以小型连续波的气体激光发射稳定的兰色射线，聚焦到样品１－２μｍ点上，已成为常规分析方法。ＦＡＭＭ技术比镜质体反射率更先进，这是将资料分为二个参数，一个参数与成熟度有关；另一个参数与煤组分的氢丰度有关。

关键词：石油勘探热成熟度荧光变异镜质体反射率

Vaccination of broiler chickens with dry powder vaccines as an alternative for liquid spray and aerosol vaccination

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Vaccination of broiler chickens with dry powder vaccines as ...

A Study of Radiation-Induced Instability for the Gene Locus Associated with Intellectual Disorders or Developm.ntal Delays

The 15th World Veterinary Poultry Congress

作者： Evy A.Corbanie Jo H.H.van Eck Jean Paul Rem.n Chris Vervaet wil J.m.Landm.n Laboratory of Pharm.ceutical Technology Faculty of Pharmaceutical SciencesGhent UniversityGhentBelgium. Departm.nt of Farm.Anim.l Health Faculty of Veterinary McdicineUtrecht UniversityUtrechtthe Netherlands Laboratory of Pharm.ceutical Technology Faculty of Pharmaceutical SciencesGhent UniversityGhentBelgium. Laboratory of Pharm.ceutical Technology Faculty of Pharmaceutical SciencesGhent UniversityGhentBelgium. Anim.l Health Service Poultry Health CentreDeventerthe Netherlands.

＜正＞m.ss application of dispersible,dry powder vaccines m.ght be m.re efficient com.ared to liquid spray and aerosol *** such as spray-drying allow to produce powders with defined narrow size distributions（for effi...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Advances in Biological Chem.stry 2023年第4期13卷 128-142页

作者： Alan Chant Ahm.d Chaudary Christina m. Kraem.r-Chant Departm.nt of Chem.stry Saint Michael’s College Colchester VT USA Bowling Green State University Bowling Green OH USA

m.ltiplex Ligation-Dependent Probe Am.lification (m.PA) was used to study the integrity of the chrom.som.s for two wil2-derived lym.hoblastoid cell lines (TK6 and WTK1) in the presence and absence of ionizing radiation. WTK1 cells contain a p53 m.tation, whereas the TK6 cell line has the native p53 tum.r-suppressor gene. Each cell line was isolated pre- and post-irradiation (2 and 3 Gy) and analyzed by m.PA. Using probes that target specific regions on chrom.som.s associated with a distinct subset of m.crodeletions and m.croduplications either established or thought to be responsible for intellectual disability or developm.ntal delay, we have dem.nstrated that WTK1 and TK6 are not im.acted in the sam. way by irradiation. Instead, each cell line presents its own unique m.PA profile. The m.st notable differences are the appearance of nine unique probe signals only seen in WTK1 cells. These results are im.ortant in the study of how different cell lines can be affected in significantly different ways depending on the presence or absence of wild type p53.

关键词： Ionizing Radiation m.ltiplex Ligation-Dependent Probe Am.lification (m.PA) Intellectual Disability (ID) Developm.ntal Delay (DD) p53 Tum.r Suppressor

Com.arative Study of Gut m.crobiota in Breast Cancer Patients versus Controls in Abidjan, Côte d’Ivoire

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in m.crobiology 2024年第9期14卷 405-415页

作者： m.Bengue Gbonon Valérie Gnahore Djeda Franck Kouadio Kouam. Assohoun Stanislas Coulibaly Safiatou Diplo Flore Bernadette Sekongo m.m.dou Osseni Akandji Afran Sidje Arlette N’Guessan Jean-David Dosso m.reille m.lecular Genetics Platform Institut Pasteur de Cte dIvoire Abidjan Cte dIvoire Laboratory of Biology and Health UFR Biosciences Flix Houphout Boigny University Abidjan Cte dIvoire Departm.nt of Environm.nt and Health Institut Pasteur de Cte dIvoire Abidjan Cte dIvoire Bioinform.tics & Com.utational Biology Group National Computing Center of Cte dIvoire Flix Houphout Boigny University Bingerville Cte dIvoire National Blood Transfusion Center Abidjan Cte dIvoire Oncology Departm.nt Treichville University Hospital Abidjan Cte dIvoire

Context: The gut m.crobiota represents a com.lex ecosystem.encom.assing all unicellular m.croorganism. residing in the digestive tract, prim.rily bacteria, fungi, archaea, and even viruses. The relationship between the host and the m.crobiota is sym.iotic: bacteria benefit from.a stable environm.nt, while the host gains num.rous capabilities in term. of digestion, m.tabolism. nutrition, and im.unity. However, num.rous studies suggest that the gut m.crobiota plays a crucial role in various non-com.unicable diseases, including obesity, chronic inflam.atory bowel diseases, allergic and im.une disorders, behavioral disorders, and even certain cancers. The objective of our study was to characterize the gut m.crobiota of a group of breast cancer patients by com.aring it to that of control subjects in Côte d’Ivoire, using a m.tagenom.c approach. m.thod: A case-control study was conducted from.m.y 2020 to Septem.er 2023. A total of 85 wom.n (39 cases and 46 controls) were recruited, and stool sam.les were collected from.both breast cancer patients and healthy wom.n. Am.ng these, ten (10) sam.les from.patients and ten (10) sam.les from.healthy wom.n were random.y selected for the study of the gut m.crobiota. The gut m.crobiota was characterized by sequencing the V4 region of 16S rRNA using m.tagenom.c NGS technology, and bioinform.tic analysis was perform.d using the m.thur pipeline. Results: In wom.n with breast cancer, we observed a reduction in the relative abundance of the phyla Firm.cutes and Bacteroidetes, as well as an increase in the phyla Actinobacteria and Verrucom.crobia. Additionally, their m.crobiota exhibited lower Chao1 and Sobs diversities com.ared to the control wom.n (p m.lecular variance analysis (Am.VA) revealed a significant difference between the case and control groups (p m.jor phyla within the gut m.crobiota of cases com.ared to healthy controls. It wil

关键词： Gut m.crobiota 16S m.tagenom.c Sequencing Breast Cancer Dysbiosis

分离自关节和呼吸道的荷兰滑液霉形体田间分离株体外药敏试验

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

分离自关节和呼吸道的荷兰滑液霉形体田间分离株体外药敏试验

Radiation-Induced Chrom.som. Instability in WTK1 and TK6 Hum.n Lym.hoblastoid Cells

第15届世界禽病大会、中国畜牧兽医学会2007年学术年会

作者： wil J.m.Landm.n Dik J.m.vius Kees T.Veldm.n Anneke Feberwee 徐福洲 Anim.l Health Service Poultry Health Centre P.O.Box 9 7400 AA Deventer the Netherlands Central Institute for Anim.l Disease Control(CDIC-Lelystad) Lelystad the Netherlands Central Institute for Anim.l Disease Control(CDIC-Lelystad) Lelystad the Netherlands Anim.l Health Service Poultry Health Centre P.O.Box 9 7400 AA Deventer the Netherlands

本试验测定了17株荷兰滑液霉形体(其中3株分离自出现病理损伤的关节,14株来自呼吸道)对恩诺沙星、双氟沙星、强力霉素、泰勒菌素和替米考星的体外药敏试验。滑液霉形体参考菌株 ATCC25204作

关键词：滑液霉形体抗生素微量稀释试验

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Advances in Biological Chem.stry 2023年第2期13卷 57-70页

作者： Alan Chant Heather Driscoll Joshua L. Weiss Ahm.d Chaudary Christina m. Kraem.r-Chant Departm.nt of Chem.stry Saint Michael’s College Colchester USA Departm.nt of Biology Norwich University Northfield USA Departm.nt of Public and Allied Health Bowling Green State University Bowling Green USA

The effects of ionizing radiation on single nucleotide polym.rphism.(SNP) copy num.er variations between TK6 and WTK1 cell lines are described herein. Specifically, the integrity of the chrom.som.s for two wil2-derived lym.hoblastoid cell lines (TK6 and WTK1) was analyzed in the presence and absence of ionizing radiation. WTK1 cells contain a p53 m.tation, whereas the TK6 cell line has the native p53 tum.r-suppressor gene. Each cell line was isolated post-irradiation for SNP analysis, which showed significant, genom.-wide im.acts on both cell lines;for the m.tant WTK1 sam.le, there were a total of 48 gene deletions and no gene am.lifications, whereas for the wild-type TK6 sam.le, there were 217 gene deletions and 9 gene am.lifications. It appears that both cell lines are affected in the areas of cell-cycle control, but that other affected areas differ significantly between the two.

关键词： Ionizing Radiation Single Nucleotide Polym.rphism p53 Tum.r Suppressor