检索结果-南通市图书馆

Modified Almost Unbiased Liu Estimator in Linear Regression Model

Communications in Mathematics and statistics 2017年第3期5卷 261-276页

作者： sivarajah Arumairajan Pushpakanthie wijekoon Postgraduate Institute of science University of PeradeniyaPeradeniyaSri Lanka Department of Mathematics and statistics Faculty of ScienceUniversity of JaffnaJaffnaSri Lanka Department of statistics and Computer science Faculty of ScienceUniversity of PeradeniyaPeradeniyaSri Lanka

In this paper,we propose a new biased estimator namely modified almost unbiased Liu estimator by combining almost unbiased Liu estimator(AULE)andridge estimator(RE)in a linear regression model when multicollinearity presents amongthe independent *** and sufficient conditions for the proposed estimator over the ordinary least square estimator,RE,AULE and Liu estimator(LE)in the mean squared error matrix sense are derived,and the optimal biasing parameters are *** illustrate the theoretical findings,a Monte Carlo simulation study is carried out and a numerical example is used.

关键词： Multicollinearity Ridge estimator Almost unbiased Liu estimator Liu estimator Modified almost unbiased Liu estimator Mean squared error matrix

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验

引用

中华高血压杂志 2018年第12期26卷 1130-1130页

作者： Web-ster R salam A de silva HA selak V stepien s Rajapakse s Amarasekara s Amarasena N Billot L de silva AP Fernando M Guggilla R Jan s Jayawardena J Maulik PK Mendis s Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom s Tisserra N senaratne V wijekoon s Wijeyasingam s Rodgers A Patel A 刘莉叶鹏

控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未... 详细信息

控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。

关键词：高血压患者随机临床试验抗高血压药物常规治疗血压控制斯里兰卡低剂量疗效差异

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

stimuli-responsive peptide assemblies:Design,self-assembly,modulation,and biomedical applications

引用

Bioactive Materials 2024年第5期35卷 181-207页

作者： Rongqiu Mu Danzhu Zhu sama Abdulmalik suranji wijekoon Gang Wei sangamesh G.Kumbar College of Chemistry and Chemical Engineering Qingdao University266071QingdaoChina Department of Biomedical Engineering&Department of Materials science and Engineering University of ConnecticutStorrs06269USA Department of Orthopaedic surgery University of Connecticut HealthFarmington06030USA

Peptide molecules have design flexibility,self-assembly ability,high biocompatibility,good biodegradability,and easy functionalization,which promote their applications as versatile biomaterials for tissue engineering and *** addition,the functionalization of self-assembled peptide nanomaterials with other additive components enhances their stimuli-responsive functions,promoting function-specific applications that induced by both internal and external *** this review,we demonstrate recent advance in the peptide molecular design,self-assembly,functional tailoring,and biomedical applications of peptide-based *** strategies on the design and synthesis of single,dual,and multiple stimuli-responsive peptide-based nanomaterials with various dimensions are analyzed,and the functional regulation of peptide nanomaterials with active components such as metal/metal oxide,DNA/RNA,polysaccharides,photosensitizers,2D materials,and others are *** addition,the designed peptide-based nanomaterials with temperature-,pH-,ion-,light-,enzyme-,and ROs-responsive abilities for drug delivery,bioimaging,cancer therapy,gene therapy,antibacterial,as well as wound healing and dressing applications are presented and *** comprehensive review provides detailed methodologies and advanced techniques on the synthesis of peptide nanomaterials from molecular biology,materials science,and nanotechnology,which will guide and inspire the molecular level design of peptides with specific and multiple functions for function-specific applications.

关键词： Peptide assemblies Molecular design Functional modulation stimuli-responsive nanomaterials Biomedical applications

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Generic and disease-specific health-related quality of life in patients with Hirschsprung disease:A systematic review and meta-analysis

引用

World Journal of Gastroenterology 2022年第13期28卷 1362-1376页

作者： Veerle Huizer Naveen wijekoon Daniëlle Roorda Jaap Oosterlaan Marc A Benninga LW Ernest van Heurn shaman Rajindrajith Joep PM Derikx Department of Pediatric surgery Emma Children's HospitalAmsterdam UMCUniversity of Amsterdam and Vrije Universiteit AmsterdamAmsterdam Reproduction and DevelopmentAmsterdam 1105 AZNetherlands Department of surgery University of Colombo and Department of Paediatric SurgeryLady Ridgeway Hospital for ChildrenColombo 00800Sri Lanka Department of Pediatrics Emma Children's HospitalAmsterdam UMCUniversity of AmsterdamEmma Neuroscience GroupAmsterdam Reproduction and DevelopmentAmsterdam 1105 AZNetherlands Department of Pediatrics Lady Ridgeway Hospital for ChildrenColombo 00800Sri Lanka

BACKGROUND Patients with Hirschsprung disease(HD)are at risk of persistent constipation,fecal incontinence or recurrent enterocolitis after surgical treatment,which in turn may impact physical and psychosocial *** health-related quality of life(HRQoL)and disease-specific health-related quality of life are relevant outcome measures to assess the impact of HD on the QoL of these *** To summarize all available evidence on HRQoL of patients with HD after surgery and the impact of possible moderating *** Pubmed,Web of sciences,Psyc Info and Embase were searched with search terms related to’Hirschsprung disease’,’Pediatrics’and’Quality of life’.Mean and standard deviation of generic HRQoL overall and domain scores were extracted from each study,as well as data describing potential factors associated with *** effect models were used for meta-analytic aggregation of generic HRQoL ***-regression was used to assess the relationship between patient and clinical characteristics and generic ***-specific HRQoL outcomes of patients with HD were systematically *** seventeen articles were included in the systematic review(n=1137 patients)and 15 in the quantitative meta-analysis(n=1024 patients).Four studies reported disease-specific ***’s age ranged between 0 and 21 ***-analytic aggregation showed a nonsignificantly impaired generic HRQoL(d=-0.168[95%CI:-0.481;0.145],P=0.293,I^(2)=94.9)in patients with HD compared to healthy ***(d=-0.042[95%CI:-0.419;0.335],P=0.829,I^(2)=95.1),psychosocial(d=-0.159[95%CI:-0.458;0.141],P=0.299,I^(2)=93.6)and social HRQoL(d=-0.092[95%CI:-0.642;0.457],P=0.742,I^(2)=92.3)were also not significantly lower compared to healthy *** was no relation between health-related outcomes and the sex of the patients and whether generic HRQoL was measured by parental proxy or ***-specific complaints of patients with HD impaired physical

关键词： Hirschsprung disease Health-related quality of life Meta-analysis systematic review Pediatrics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：