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Effect of Sacubitril-Valsartan Combined with Zhenyuan Capsule in the Treatment of Chronic Heart Failure Comorbid Anxiety and Depression and Its Effect on Inflammatory Factors

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Natural Science 2022年第6期14卷 241-250页

作者： Jianhong Qin wenzhi mo Lixin Xie Erneng Zhou Guijiao Li Rongfu Liang Xuenuo Wu Department of Cardiology Nanning Third People’s Hospital Nanning China

Objective: To investigate the effect of sacubitril-valsartan combined with Zhenyuan capsule in the treatment of chronic heart failure comorbid anxiety and depression and its effect on the level of inflammatory factors. Methods: A total of 106 patients with chronic heart failure comorbid anxiety and depression from February 2020 to March 2022 were continuously enrolled and divided into control group (36 cases), observation group A (36 cases) and observation group B (34 cases) according to treatment methods. All groups were given conventional treatment. On the basis of routine treatment, the control group, observation group A and observation group B were given valsartan, sacubitril-valsartan and sacubitril-valsartan plus Zhenyuan Capsules for the treatment of consecutive 8 weeks. The patients in the 3 groups were evaluated by the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) before and after treatment, and the clinical efficacy of heart failure was evaluated, and the detection of left ventricular ejection fraction (LVEF), left ventricular end systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD), N terminal brain natriuretic peptide (NT-proBNP), tumor necrosis factor alpha (TNF alpha), interleukin 6 (IL-6), c-reactive protein (CRP) was conducted. Results: The clinical efficacy rate and total effective rate of heart failure in observation group A and observation group B were significantly higher than those in the control group (P < 0.05), and the observation group B was higher than the observation group A (P < 0.05);SAS and SDS scores in observation group A and observation group B were significantly lower than the control group (P < 0.05), and observation group B was lower than observation group A (P < 0.05);The LVEF in the three groups was all increased compared with those before treatment, and the levels of LVESD, LVEDD, NT-proBNP, TNF-α, IL-6, and hs-CRP were all decreased compared with those before treatment;The changes

关键词： Heart Failure Anxiety Depression Sacubitril Valsartan Zhenyuan Capsule Inflammatory Factors

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新型手性三齿PNN配体锰配合物催化的芳香酮类化合物的不对称氢化反应研究

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化学学报 2024年第7期82卷 736-741页

作者：江杏杏武卫龙任慧莹张凤莫文枝卢志强三峡大学生物与制药学院湖北宜昌443002 洛阳师范学院化学化工学院河南洛阳471934

非贵金属相较于贵金属具有廉价、低毒的特点,因此发展用于酮的不对称催化氢化的高效、低毒的非贵金属催化剂在近些年受到广泛关注,其中手性三齿PNN和PNP配体的锰配合物在多种酮的催化不对称氢化中表现出优异的性能,但就底物类型和催化... 详细信息

非贵金属相较于贵金属具有廉价、低毒的特点,因此发展用于酮的不对称催化氢化的高效、低毒的非贵金属催化剂在近些年受到广泛关注,其中手性三齿PNN和PNP配体的锰配合物在多种酮的催化不对称氢化中表现出优异的性能,但就底物类型和催化效率而言仍有待进一步提升.基于此,本工作将廉价易得的8-氨基喹啉骨架引入面手性二茂铁中合成了一系列含芳胺NH的三齿PNN配体L1~L4,并将其Mn配合物成功用于简单芳基酮、苯并环烷酮、α-氨基酮等的催化不对称氢化(达到98%ee,1000 TON).反应使用K_(2)CO_(3)作碱,EtOH作溶剂,对(S)-phenylephrine的重要中间体β-氨基醇2-49进行克级规模制备,证明了该催化体系具有潜在的工业应用性.对配合物Mn-L的高分辨质谱和红外光谱的初步表征和分析,暗示其结构中含两个CO.

关键词：芳胺NH 手性PNN配体锰配合物催化不对称氢化手性醇

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关于几种海底柱状取样器的分析和研制方向的探讨

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海洋技术 1984年第2期 57-68页

作者：莫文治陈庆海洋地质调查局

本文对国内现用的三种基本海底柱状取样器及国外二种新型取样器进行了分析和述评,并结合我国海域可供船只使用的条件,对今后研制新的海底柱状取样器进行了探讨。

关键词：取样器取样长度振动器重力取样管海底底质底柱

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Catalyst–Support Interaction in Polyaniline‑Supported Ni_(3)Fe Oxide to Boost Oxygen Evolution Activities for Rechargeable Zn‑Air Batteries

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Nano-Micro Letters 2025年第1期17卷 176-190页

作者： Xiaohong Zou Qian Lu Mingcong Tang Jie Wu Kouer Zhang wenzhi Li Yunxia Hu Xiaomin Xu Xiao Zhang Zongping Shao Liang An Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Jiangsu Key Laboratory of Atmospheric Environment monitoring and Pollution Control Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environmental Science and TechnologyNanjing University of Information Science and TechnologyNanjing 210044People’s Republic of China Department of Chemistry The Chinese University of Hong KongMa Lin BuildingShatinHong Kong SAR 999077People’s Republic of China WA School of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6102Australia Research Institute for Advanced Manufacturing The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China

Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction(OER).Here we modulate the catalyst–support interaction in polyaniline-supported Ni_(3)Fe oxide(Ni_(3)Fe oxide/PANI)with a robust hetero-interface,which significantly improves oxygen evolution activities with an overpotential of 270 mV at 10 mA cm^(-2)and specific activity of 2.08 mA cm_(ECSA)^(-2)at overpotential of 300 mV,3.84-fold that of Ni_(3)Fe *** is revealed that the catalyst–support interaction between Ni_(3)Fe oxide and PANI support enhances the Ni–O covalency via the interfacial Ni–N bond,thus promoting the charge and mass transfer on Ni_(3)Fe *** the excellent activity and stability,rechargeable Zn-air batteries with optimum Ni_(3)Fe oxide/PANI are assembled,delivering a low charge voltage of 1.95 V to cycle for 400 h at 10 mA cm^(-2).The regulation of the effect of catalyst–support interaction on catalytic activity provides new possibilities for the future design of highly efficient OER catalysts.

关键词： Catalyst-support interaction Supported catalysts Heterointerface Oxygen evolution reaction Zn-air batteries

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桄榔粉结构特性及其体外升糖指数研究

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食品与发酵工业 2024年第23期50卷 264-270页

作者：伍秋蓉莫文芝杨富才刘宇凡卢玉翠廖夏云广西中医药大学药学院广西南宁530021 广西药食同源资源开发重点实验室广西南宁530021

以桄榔粉为主要研究原料,将马铃薯淀粉和玉米淀粉作为桄榔粉的比较对象,对其淀粉颗粒形态、粒径大小、晶体类型、直链淀粉含量进行探讨,并通过体外消化试验得出其淀粉组分、淀粉体外水解曲线,最后计算得出淀粉样品的预测升糖指数(glycem... 详细信息

以桄榔粉为主要研究原料,将马铃薯淀粉和玉米淀粉作为桄榔粉的比较对象,对其淀粉颗粒形态、粒径大小、晶体类型、直链淀粉含量进行探讨,并通过体外消化试验得出其淀粉组分、淀粉体外水解曲线,最后计算得出淀粉样品的预测升糖指数(glycemic index,GI)。研究发现桄榔粉颗粒呈扁长的椭圆形,表面较光滑,且有部分凹陷;桄榔粉颗粒平均粒径比玉米淀粉大,比马铃薯淀粉小。桄榔粉、马铃薯淀粉、玉米淀粉的晶体结构分别为C型、B型、A型。桄榔粉的抗性淀粉和直链淀粉含量均高于玉米淀粉,低于马铃薯淀粉;桄榔粉的慢消化淀粉含量比马铃薯淀粉高,比玉米淀粉低;桄榔粉的快消化淀粉含量最低。3种淀粉的水解率由小到大为:马铃薯淀粉<桄榔粉<玉米淀粉。3种淀粉的GI值由小到大排列为:马铃薯淀粉(52.10)<桄榔粉(53.00)<玉米淀粉(76.74)。桄榔粉为低GI食物,与玉米淀粉相比,桄榔粉具有更强的抗消化性,GI值更低,因此,桄榔粉比玉米淀粉更适合作为糖尿病患者食用原料及产品开发原料。

关键词：桄榔粉抗性淀粉体外消化淀粉水解率升糖指数

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华佗夹脊穴为主治疗腰椎间盘突出症研究概况

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广西中医药 2021年第1期44卷 74-77页

作者：张卓黄子恩黄波莫雯智林辰广西中医药大学广西南宁530200

腰椎间盘突出症为临床常见病、多发病,主要是由于腰椎间盘发生退变后,复因劳损或外伤作用引起纤维环破裂、髓核突出而导致神经根压迫而出现的一系列以腰痛并放射至下肢痛伴麻木及活动功能障碍为主要临床症状的病症,且发病年龄有年轻化趋... 详细信息

腰椎间盘突出症为临床常见病、多发病,主要是由于腰椎间盘发生退变后,复因劳损或外伤作用引起纤维环破裂、髓核突出而导致神经根压迫而出现的一系列以腰痛并放射至下肢痛伴麻木及活动功能障碍为主要临床症状的病症,且发病年龄有年轻化趋势,大大降低患者的生活质量。由于该病病程长、复发率高,西医大都采用外科手术方法,但术后效果不理想,副作用较明显,且治疗费用相对偏高。

关键词：华佗夹脊穴腰椎间盘突出症综述

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基于壮医经筋理论诊治硬瘫症

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亚太传统医药 2021年第9期17卷 7-10页

作者：梁冬媚韦英才蓝毓营许宗迪莫雯智广西中医药大学壮医药学院广西南宁530000

硬瘫属中风常见后遗症之一,不仅使患者的生活品质下降,也增加了家庭与社会的经济压力。因此,积极防治硬瘫,对个人、家庭及社会均具有重要意义。从祖国传统医学及壮医学探讨本病的病因病机,基于壮医经筋理论,认为"筋纵则瘫",提出采用经... 详细信息

硬瘫属中风常见后遗症之一,不仅使患者的生活品质下降,也增加了家庭与社会的经济压力。因此,积极防治硬瘫,对个人、家庭及社会均具有重要意义。从祖国传统医学及壮医学探讨本病的病因病机,基于壮医经筋理论,认为"筋纵则瘫",提出采用经筋燔针疗法治疗硬瘫。经临床案例诊治分析后,认为在对硬瘫患者的治疗中,以"解筋结,通火路,养经筋,解筋纵"为治疗原则,通过经筋燔针疗法治疗,对改善患者肌张力程度及生活质量有着积极意义。

关键词：硬瘫中风壮医经筋理论经筋燔针疗法

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FEM Analysis on Acoustic Performance of Wall Flow Diesel Particulate Filters

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Chinese Journal of Mechanical Engineering 2011年第4期24卷 701-706页

作者： GAO wenzhi FENG Liming State Key Laboratory of Engines Tianjin University Tianjin 300072 China

Diesel powered vehicles, in compliance with the more strict exhaust emission standards such as Euro V, is likely to require a diesel particulate filter （DPF）. A DPF used on a vehicle will affect the acoustic emission of the diesel engine, so it is important to investigate the sound propagation rule in DPF and further to propose the optimum DPF design. However, due to the geometrical complexity of the DPF, the traditional analysis method, such as analytical method, can not assess the acoustic performance of DPF accurately in medium and high frequency band. In this paper, a combined approach of finite element analysis and viscosity correction is proposed to predict acoustic performance of DPF. A simplified model of the full DPF is established and is used to analyze the sound propagation characteristic of the DPF. The distribution of the sound pressure and velocity, the transmission matrix of the DPF are obtained using the finite element method. In addition, the method of the viscosity correction is used in the transmission matrix of the DPF to evaluate the acoustic performance of DPF. Based on the FEM computation and the viscosity correction, the transmission losses under the rated load and idle condition of a diesel engine are calculated. The calculation results show that DPF can effectively attenuate exhaust noise, and sound attenuation increase with the rise of the frequency. Sound attenuation is better under rated condition than idle condition of diesel engine, particularly in frequency above 1 000 Hz.

关键词： diesel particulate filter acoustic performance FEM model viscosity correction

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Host-guest cocrystals boost thermally activated delayed fluorescence materials

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Science China Chemistry 2024年第10期67卷 3179-3180页

作者： wenzhi Yang Jiong Zhou Department of Chemistry College of SciencesNortheastern UniversityShenyang 110819China

Organic light-emitting diodes(OLEDs)play an important role in organic display and lighting *** activated delayed fluorescence(TADF)materials have shown great potential in the OLED field because they can theoretically ... 详细信息

关键词： Host diodes delayed

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Aligned carbon nanotubes for lithium-ion batteries:A review

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Nano Research 2023年第11期16卷 12384-12410页

作者： Chinaza E.Nwanno wenzhi Li Department of Physics Florida International UniversityMiamiFL 33199USA

Nanoscale materials are gaining massive attention in recent years due to their potential to alleviate the present electrochemical electrode *** high conductivity(both thermally and electrically),high chemical and electrochemical stability,exceptional mechanical strength and flexibility,high specific surface area,large charge storage capacity,and excellent ionadsorption,carbon nanotubes(CNTs)remain one of the most researched of other nanoscale materials for electrochemical energy *** than having them packed at random,CNTs perform better when packed/grown to order,vertically or horizontally aligned to a *** study presents an overview of the impact of CNT alignment on the electrochemical performance of lithium-ion batteries(LIBs).The unique properties of vertically aligned CNTs(VACNTs)for LIB application were ***,the mechanisms of charge storage and electrochemical performances in VACNT-based(pristine and composites)anodes and cathodes of LIBs were succinctly *** the end,the existing challenges and future directions in the field were also briefly discussed.

关键词： nanoscale vertically aligned carbon nanotubes(VACNTs) composites lithium-ion batteries(LIBs) anodes cathodes

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