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中医治疗脾肾阳虚型糖尿病肾病研究进展

中国中医药现代远程教育 2024年第19期22卷 179-182页

作者：朱春丽韩文霞山东中医药大学第一临床医学院山东济南250014 山东第一医科大学附属省立医院内分泌代谢病科山东济南250021

糖尿病肾病(DKD)是糖尿病(DM)患者常见的微血管并发症之一,也是终末期肾病的主要原因。中期DKD患者中医临床证型大多为脾肾阳虚,西医药对此疗效尚有令人不满意之处。近年来,许多临床研究证实中医药治疗脾肾阳虚型DKD安全有效。此文总结... 详细信息

糖尿病肾病(DKD)是糖尿病(DM)患者常见的微血管并发症之一,也是终末期肾病的主要原因。中期DKD患者中医临床证型大多为脾肾阳虚,西医药对此疗效尚有令人不满意之处。近年来,许多临床研究证实中医药治疗脾肾阳虚型DKD安全有效。此文总结近年来的文献,为中医治疗脾肾阳虚型DKD提供依据。

关键词：关格糖尿病肾病脾肾阳虚证中医药疗法综述

Late Eocene pollen records and palaeoenvironmental changes in northern Tibetan Plateau

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Science China Earth Sciences 2008年第8期51卷 1089-1098页

作者： MIAO YunFa FANG XiaoMin SONG ZhiChen WU FuLi han wenxia DAI Shuang SONG ChunHui Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100085China National Laboratory of Western China Environmental Systerms of Education of China&Department of Geography Lanzhou UniversityLanzhou 730000China Nanjing Institute of Geology and Palaeontology Chinese Academy of SciencesNanjing 210008China

The Eocene palaeovegetation landscape and palaeoclimate reconstructed from the pollen records in the Jiuquan Basin, northwest China provide some important information on the early uplift of the Tibetan Plateau and the origin and evolution of the aridification in northwest China. The records show the arid-semiarid scrubs with open forest palynofloras controlled by the subtropical high existed in northwest China during the 40.2-33.4 Ma. Four pollen assemblages are found: Nitrariadites-Cheno-podipollis-Pinaceae assemblage (40.2-37.9 Ma) is followed by Chenopodipollis-Nitrariadites assemblage (37.9-34.6 Ma), Pinuspollenites & Abietineaepollenites-Chenopodipollis assemblage (34.6-33.9 Ma), and Chenopodipollis-Nitrariadites assemblage (33.9-33.4 Ma). The percentage of thermophilic types is in anti-correlation with that of the dry types, which means the palaeoclimate is relatively warmwet or cold-dry during most of that time. Such aridity may be related to the water vapor reduction and the planetary wind system movement northward in response to the cooling caused by small-ephemeral icesheets.

关键词： Tibetan Plateau pollen records Eocene planetary arid zone palaeoenvironment cooling

Analytical Modeling of Disaster-induced Load Loss for Preventive Allocation of Mobile Power Sources in Urban Power Networks

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Journal of Modern Power Systems and Clean Energy 2024年第4期12卷 1063-1073页

作者： Zhuorong Wang Qingxin Shi Ke Fan Haiteng han wenxia Liu Fangxing Li School of Electrical&Electronics Engineering North China Electric Power UniversityBeijing 102206China College of Energy and Electrical Engineering Hohai UniversityNanjing 211100China The University of Tennessee Knoxville TN 37996USA

Continuous power supply of urban power networks(UPNs)is quite essential for the public security of a city be-cause the UPN acts as the basis for other infrastructure *** recent years,UPN is threatened by extreme weather *** accurate modeling of load loss risk under extreme weather is quite essential for the preventive action of ***-sidering the forecast intensity of a typhoon disaster,this paper proposes analytical modeling of disaster-induced load loss for preventive allocation of mobile power sources(MPSs)in ***,based on the topological structure and fragility model of overhead lines and substations,we establish an analytical load loss model of multi-voltage-level UPN to quantify the spatial dis-tribution of disaster-induced load loss at the substation ***,according to the projected load loss distribution,a pre-ventive allocation method of MPS is proposed,which makes the best use of MPS and dispatches the limited power supply to most vulnerable areas in the ***,the proposed meth-od is validated by the case study of a practical UPN in China.

关键词： Load loss fragility model pre-disaster allocation mobile power source urban power network

Deep Drilling Campaign in the Western Qaidam Basin,NE Tibetan Plateau and their Revealed Global Temperature Forcing of Salt Formation in the Late Miocene-Quaternary

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Acta Geologica Sinica(English Edition) 2014年第S1期88卷 216-217页

作者： FANG Xiaomin LI Minghui Erwin APPEL WANG Jiuyi han wenxia ZhanG Weilin YANG Yibo CAI Maotang Key Laboratory of Continental Collision and Plateau Uplift & Institute of Tibetan Plateau Research Chinese Academy of Sciences Department of Geosciences University of Tübingen Key Laboratory of Salt Lake Resources and Chemistry & Qinghai Institute of Salt Lakes Chinese Academy of Sciences

The Qaidam Basin in the NE Tibetan Plateau has contributed the largest amount of potash in ***,how the potash was formed has long been a subject of *** we carried out a deep drilling

关键词： SG Deep Drilling Campaign in the Western Qaidam Basin,NE Tibetan Plateau and their Revealed Global Temperature Forcing of Salt Formation in the Late Miocene-Quaternary NE

Response of grain size of Quaternary gravels to climate and tectonics in the northern Tibetan Plateau

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Science China Earth Sciences 2007年第1期50卷 81-91页

作者： FU KaiDao FANG XiaoMin GAO JunPing han wenxia LI LiLi MOE National Laboratory of Western China’s Environmental Systems&College of Resource and Environment Lanzhou UniversityLanzhou 730000China Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100085China 不详

The widely distributed thick gravel deposits along the rim of the Tibetan Plateau have been long thought to be the product of rapid tectonic uplift of the plateau. However, this has been challenged by recent works that suggest these thick gravels may be the result of climate change. In this paper we carried out a detailed field measurement of gravel grain sizes from the Jiuquan and Gobi Gravel Beds in the top of the Laojunmiao section in the Jiuxi Basin in the northern margin of Qilian Mts. (northern Tibetan Plateau). The results suggest that the grain sizes of the Jiuquan and Gobi Gravel Beds over the last 0.8 Ma are characterized by nine coarse-fine cycles having strong 100-ka and 41-ka periodicities that correlate well with the loess-paleosol monsoon record and isotopic global climatic record from deep sea sediments as well as by a long trend of coarsening in gravel grain size. The coarse gravel layers were formed during the warm-humid interglaciations while the fine layers correspond to the cold-dry glaciations. Because the paleoclimate in NW China began to get dramatically drier after the mid-Pleistocene, we think the persistent coarsening of gravel grain size was most probably caused by the rapid uplift of the northern Tibetan Plateau, and that the orbital scale cyclic variations in gravel grain size were driven by orbital forcing factors that were superimposed on the tectonically-forced long-term coarsening trend in gravel size. These findings also shed new light on the interaction results of climate and tectonics in relation to the uplift of the Tibetan Plateau.

关键词： Tibetan Plateau Jiuxi Basin gravels grain sizes climate changes tectonics.

An 8.1Ma calcite record of Asian summer monsoon evolution on the Chinese central Loess Plateau

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Science China Earth Sciences 2007年第3期50卷 392-403页

作者： CHEN XiuLing FANG XiaoMin AN ZhiSheng han wenxia WANG Xin BAI Yan HONG Ye Key Laboratory of Western China’s Environmental Systems(MOE)and College of Resources and Environment Lanzhou Univer-sityLanzhou 730000China Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100085China State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710075China College of Atmospheric Science Lanzhou UniversityLanzhou 730000China

Carbonates in loess-red clay sequences consist mainly of calcite and dolomite. The EDTA analysis of carbonates in different size fractions and magnetic susceptibility reveal that calcite is a sensitive index of summer monsoon. The chemical analysis of carbonates and calcite from an 8.1 Ma loess-red clay sequence at Chaona on the Chinese central Loess Plateau shows that the evolution of the Asian summer monsoon experienced four stages, namely 8.1―5.5 Ma, 5.5―2.8 Ma, 2.8―1.5 Ma and 1.5―0 Ma, with increasing intensification and fluctuation, suggesting a possible combining impacts of uplift of the Tibetan Plateau and global changes on the Asian summer monsoon.

关键词： carbonates calcite evolution of Asian summer monsoon red clay-loess Chinese Loess Plateau

Targeting NRP1 axis as a strategy for treating energy metabolism impairment induced by SARS-CoV-2 spike

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Science China(Life Sciences) 2024年第10期67卷 2277-2279页

作者： Lihui Zhang Wanting Hu Jingxuan Li Yuehan Li Feng Liu Wenyi Xiao Ning Jiang Zhiyong Xiao Lu han wenxia Zhou Beijing Institute of Pharmacology&Toxicology Beijing 100850China State Key Laboratory of Toxicology and Medical Countermeasures Beijing Institute of Pharmacology&ToxicologyBeijing 100850China School of Chinese Materia Medica Tianjin University of Traditional Chinese MedicineTianjin 301617China

Dear Editor,Free spike protein of SARS-CoV-2 alone can cause abnormal energy metabolism(Table S1 in Supporting Information),and limited research suggested a potential correlation between spike-induced mitochondrial da... 详细信息

关键词： metabolism ACE2

Intensified tectonic deformation and uplift of the Altyn Tagh range recorded by rock magnetism and growth strata studies of the western Qaidam Basin, NE Tibetan Plateau

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Intensified tectonic deformation and uplift of the Altyn Tag...

Paleogeography control of Indian monsoon intensification and expansion at 41 Ma

2015中国地球科学联合学术年会

作者： Tao Zhang wenxia han Xiaomin Fang Weilin Zhang Chunhui Song Maodu Yan Key Laboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau Research CAS Key Laboratory of Salt Lake Resources and Chemistry Qinghai Institute of Salt Lakes Chinese Academy of Sciences CAS Center for Excellence in Tibetan Plateau Earth Sciences School of Earth Sciences & Key Laboratory of Western China’s Mineral Resources of Gansu Province

The Altyn Tagh range is the tectonically and geographically northern edge of the Tibetan Plateau,precise dating of its activities is essential for understanding the possible mechanisms of the Tibetan Plateau uplift and its effects on climate *** the framework of basin-mountain coupling,both magnetic susceptibility and rock magnetic research were carried out on the Late Cenozoic sediments of the Honggouzi section（7-5 Ma）in the western Qaidam *** study attempts to find out the evolution history of tectonic and climatic changes and to detect their interactions in the Altyn Tagh *** results showed that magnetic susceptibility records kept relatively low and stable values before0Ma,and rapidly increased since0 *** rock magnetic results revealed that paramagnetic minerals,maghemite and hematite have been dominated during the early periods（>10 Ma）in the Honggouzi section,and were replaced by magnetite and maghemite after that time.A detailed comparison of magnetic susceptibility records in the Honggouzi section with tectonic and climate records from the study areas and surrounding regions were also carried *** with sedimentary facies,lithology and angular unconformity in the sequence,as well as seismostratigraphy data,paleocurrent study,provenance and conceptual models analyses,we argue that the0 Ma shift in the HGZ section might be caused by the uplift of the Altyn Tagh range during that time.

关键词： Rock magnetism growth strata tectonic uplift Altyn Tagh range Qaidam Basin

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Science Bulletin 2021年第22期66卷 2320-2328,M0004页

作者： Xiaomin Fang Maodu Yan Weilin Zhang Junsheng Nie wenxia han Fuli Wu Chunhui Song Tao Zhang Jinbo Zan Yongpeng Yang State Key Laboratory of Tibetan Plateau Earth System Resources and EnvironmentInstitute of Tibetan Plateau Research(TPESRE)Chinese Academy of SciencesBeijing 100101China Key Laboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Key Laboratory of Western China’s Environments of Ministry of Education Lanzhou UniversityLanzhou 730000China Shandong Provincial Key Laboratory of Water and Soil Conservation&Environmental Protection School of Resource and Environmental SciencesLinyi UniversityLinyi 276000China School of Earth Sciences&Key Laboratory of Western China’s Mineral Resources of Gansu Province Lanzhou UniversityLanzhou 730000China

As a crucial part of the Asian monsoon stretching from tropical India to temperate East Asia, the Indian monsoon(IM) contributes predominant precipitation over Asian continent. However, our understanding of IM’s onset, development and the underlying driving mechanisms is limited. Increasing evidence indicates that the IM began in the Eocene or even the Paleocene and was unexceptionally linked to the early rise of the Tibetan Plateau(TP). These were challenged by the heterogeneous and diachronous uplift of the TP and all the reported records were confined to tropical zone under tropical monsoon driven by the Intertropical Convergence Zone(ITCZ) that is irrelevant to the TP. Therefore, reliable paleoclimatic records from the extra-tropical IM region is crucial to reveal how the tropical IM expanded to subtropical and temperate zones and what driving factors might be related to it. Here we present robust Eocene paleoenvironmental records from central Yunnan(~26°N) in subtropical East Asia. The multiproxy results of two sites demonstrate a consistent sudden switch from a dry environment in the early Eocene to a seasonally wet one at 41 Ma, suggesting a jump of the tropical IM to the southern subtropical zone at 41 *** full collision of India with Asia, and the resulting changes in paleogeography at 41 Ma(closure of the Neotethys sea, retreat of the Paratethys seas, fast northward movement of the southern margin of the TP and rise of the central TP), aided by synchronous Antarctic cooling, might have worked together to drive the IM enhancement and northward expansion.

关键词： Asia paleogeography Indian tropical monsoon Eocene paleoenvironment Subtropical monsoon onset Driven factors and forcings