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Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes

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Eye and Vision 2024年第2期10卷 22-30页

作者： Ling Wei Kaiwen Cheng Wenwen He Xiangjia Zhu Yi Lu Department of Ophthalmology and Eye Institute Eye and ENT Hospital of Fudan UniversityShanghai 200031China Key Laboratory of Myopia(Fudan University)Key Laboratory of MyopiaShanghai Key Laboratory of Visual Impairment and Restoration National Health CommissionChinese Academy of Medical ScienceShanghai 200031China State Key Laboratory of Medical Neurobiology Fudan UniversityShanghai 200031China

Background:The accuracy of using total keratometry(TK)value in recent IOL power calculation formulas in highly myopic eyes remained unknown.Methods:Highly myopic patients who underwent uneventful cataract surgery were prospectively enrolled in this prospective comparative study.At one month postoperatively,standard deviation(SD)of the prediction errors(PEs),mean and median absolute error(MedAE)of 103 highly myopic eyes were back-calculated and compared among ten formulas,including XGboost,RBF 3.0,Kane,Barrett Universal II,Emmetropia Verifying Optical 2.0,Cooke K6,Haigis,SRK/T,and Wang-Koch modifications of Haigis and SRK/T formulas,using either TK or standard keratometry(K)value.Results:In highly myopic eyes,despite good agreement between TK and K(P>0.05),larger differences between the two were associated with smaller central corneal thickness(Phe refractive errors,TK method showed no differences compared to K method.The XGBoost,RBF 3.0 and Kane ranked top three when considering SDs of PEs.Using TK value,the XGboost calculator was comparable with the RBF 3.0 formula(P>0.05),which both presented smaller MedAEs than others(all Phe percentage of eyes within±0.50 D or±0.75 D of PE,the XGBoost TK showed comparable percentages with the RBF 3.0 TK formula(74.76%vs.66.99%,or 90.29%vs.87.38%,P>0.05),and statistically larger percentages than the other eight formulas(Phe XGboost enhancement calculator and RBF 3.0 formula using TK showed the most promising outcomes in highly myopic eyes.

关键词： High myopia Total keratometry Cataract surgery IOL power calculation

Morphological features of anterior segment:factors influencing intraocular pressure after cataract surgery in nanophthalmos

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Eye and Vision 2020年第2期7卷 454-464页

作者： Qiang Lu Wenwen He Yi Lu Xiangjia Zhu Department of Ophthalmology Eye and EarNoseand Throat HospitalFudan University83 Fenyang RoadShanghai 200031People’s Republic of China Eye Institute Eye and EarNoseand Throat Hospital of Fudan UniversityShanghai 200031People’s Republic of China Key Laboratory of Myopia Ministry of HealthShanghai 200031People’s Republic of China Shanghai Key Laboratory of Visual Impairment and Restoration Shanghai 200031People’s Republic of China

Purpose:To investigate the anterior segment in nanophthalmic eyes and their association with intraocular pressure after cataract surgery.Methods:Thirty-two nanophthalmic eyes(axial length[AL]herence tomography was used to compare the anterior segment structures between the two groups.The associations between the anterior segment characteristics of nanophthalmic eyes and postoperative intraocular pressure(IOP)were also investigated.Results:The IOP-lowering effect of cataract surgery was remarkably insufficient in nanophthalmic eyes.Peripheral anterior synechiae(PAS)were observed in 56%(18/32)of nanophthalmic eyes,and a characteristic boomerangshaped iris was observed in 28%(9/32).The anterior surface of the iris seemed“smoother”in nanophthalmic eyes than in normal eyes.Schlemm’s canal(SC)diameter,SC area,trabecular meshwork(TM)thickness,TM width,and TM area were generally smaller in the nanophthalmic eyes.Younger age,higher preoperative IOP,broader PAS,and smaller SC area were main contributors to higher postoperative IOP.AL and SC diameter may also be of great importance in IOP prediction in patients without glaucoma surgery and PAS.Conclusions:The morphological features of the anterior segment in nanophthalmic eyes are significantly different from those of normal eyes.Influencing factors such as age,AL,preoperative IOP,extent of PAS,SC and TM size could all be prognostic for IOP after cataract surgery in nanophthalmic eyes.

关键词： Nanophthalmos Anterior segment Intraocular pressure Catara

Measurement of crystalline lens tilt in high myopic eyes before cataract surgery using swept-source optical coherence tomography

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Eye and Vision 2020年第1期7卷 128-135页

作者： Qiang Lu Wenwen He Dongjin Qian Yi Lu Xiangjia Zhu Department of Ophthalmology Eye and EarNoseand Throat HospitalFudan University83 Fenyang RoadShanghai 200031People’s Republic of China Eye Institute Eye and EarNoseand Throat Hospital of Fudan UniversityShanghai 200031People’s Republic of China Key Laboratory of Myopia Ministry of HealthShanghai 200031People’s Republic of China Shanghai Key Laboratory of Visual Impairment and Restoration Shanghai 200031People’s Republic of China

Background:To measure the crystalline lens tilt in eyes with various degrees of myopia before cataract surgery using swept-source optical coherence tomography(SS-OCT).Methods:We used SS-OCT(IOLMaster 700)to scan 131 emmetropic eyes(axial length30 mm,respectively)as part of the routine preoperative examination before cataract surgery.SS-OCT involved B-scans along six meridians.The data were analyzed to assess the magnitude and orientation of the lens tilt and their correlation with other optical biometric parameters.Result:The mean tilt was 3.36±0.98°in emmetropic eyes,3.07±1.04°in mild/medium myopic eyes,and 2.35±1.01°in high myopic eyes.Tilt correlated significantly and inversely with axial length(Pearson’s r=−0.427,Phe crystalline lens tilt predominantly faced the upper outer quadrant relative to the visual axis,symmetrically in both eyes,with mean angles of 24.32°and 147.36°in the right and left eyes,respectively.The variability in the lens tilt direction increased with increasing axial length(χ^(2) test,Phe magnitude of crystalline lens tilt decreased with increasing axial length.The direction of tilt was predominantly towards the upper outer quadrant in both eyes.The variability in the tilt orientation increased with increasing axial length.Trial registration:NIH(clinicaltrial.gov),NCT03062085.Registered 23 February 2017.

关键词： Crystalline lens tilt Orientation Magnitude High myopia Swept-source optical coherence tomography

Preparation of ZIF-8@PEBAX/PVDF nanocomposite membrane by the combination of self-assembly and in-situ growth for removing thiophene from the model gasoline

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Chinese Journal of Chemical Engineering 2023年第12期64卷 177-187页

作者： Zhesai Zhao Qingwen Han Wenwen He Xiaolong Han School of Chemical Engineering Northwest UniversityXi’an 710069China Hubei Three Gorges Laboratory Yichang 443007China School of Chemistry and Life Science Advanced Institute of Materials ScienceChangchun University of TechnologyChangchun 130012China

Metal-organic frameworks(MOFs)have gained attention in the development of MOFs/polymer hybrid membranes for pervaporation.However,the agglomeration of MOFs particles and interfacial defects limit its further application.In this study,we present a novel approach to fabricate a ZIF-8@PEBAX/PVDF nanocomposite membrane for removing thiophene from the model gasoline by combination of selfassembly and in-situ growth.Firstly,a PVDF supporting membrane was modified to have a negative charge.Next,positively charged zinc ions were attracted onto the negatively charged PVDF supporting membrane through electrostatic interaction.Afterwards,the Zinc ions deposited PVDF membrane was immersed into dimethylimidazole solution to form a uniform ZIF-8 layer.Finally,the ZIF-8 layer was coated with poly(ether-block-amide)(PEBAX)using the pouring method.Experimental results showed that the separating efficiency of the ZIF-8@PEBAX/PVDF nanocomposite membrane was improved significantly compared to that of pristine PEBAX membrane.The optimal permeation flux and enrichment factor of membrane were 27.80 kg(m^(2)h)^(-1)and 6.9,respectively.

关键词： Nanocomposite membrane ZIF-8 nanoparticles PEBAX Thiophene

Lens thickness and associated ocular biometric factors among cataract patients in Shanghai

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Eye and Vision 2021年第1期8卷 214-222页

作者： Jiaqi Meng Ling Wei Wenwen He Jiao Qi Yi Lu Xiangjia Zhu Eye Institute and Department of Ophthalmology Eye&ENT HospitalFudan University83 Fenyang RoadXuhui DistrictShanghai 200031China Key Laboratory of Myopia Ministry of HealthShanghaiChina Key Laboratory of Visual Impairment and Restoration ShanghaiChina Key NHC key Laboratory of Myopia(Fudan University) ShanghaiChina Laboratory of Myopia Chinese Academy of Medical SciencesShanghaiChina

Background:To evaluate the distribution of lens thickness(LT)and its associations with other ocular biometric factors among cataract patients in Shanghai.Methods:Twenty-four thousand thirteen eyes from 24,013 cataract patients were retrospectively included.Ocular biometric factors including LT,central corneal thickness(CCT),anterior chamber depth(ACD),white-to-white(WTW)distance,anterior corneal curvature,and axial length(AL)were obtained using the IOLMaster700.The associations between LT and general or ocular factors were assessed.Results:The mean age was 62.5±13.6 years and 56.1%were female.The mean LT was 4.51±0.46 mm.The LT was greater in older patients(Phen decreased with longer AL in normal eyes and moderate myopic eyes,but increased again as AL increased in highly myopic eyes.Thickest LT was found in the 20.01-22mm AL group.The correlation between LT and other biometric factors remained significant when stratified by ALs.Conclusions:In a large Chinese cataractous population,we found that the thicker lens may be associated with older age,male gender,thicker CCT,shallower ACD,larger WTW,and flatter anterior corneal curvature.As AL increased,the change of LT was nonlinear,with the thickest lens seen in the 20-22mm AL group.

关键词： Lens thickness Cataract Ocular biometry Axial length

Decentration and tilt of plate-haptic multifocal intraocular lenses in myopic eyes

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Eye and Vision 2020年第1期7卷 162-170页

作者： Jiaqi Meng Wenwen He Xianfang Rong Ao Miao Yi Lu Xiangjia Zhu Eye Institute Eye and ENT Hospital of Fudan University83 Fenyang RoadShanghai 200031China Key Laboratory of Myopia Ministry of HealthShanghaiChina Key Laboratory of Visual Impairment and Restoration ShanghaiChina Key NHC key Laboratory of Myopia(Fudan University) ShanghaiChina Laboratory of Myopia Chinese Academy of Medical SciencesShanghaiChina

Background:To investigate the decentration and tilt of plate-haptic multifocal intraocular lenses(MfIOLs)in myopic eyes.Methods:Myopic(axial length[AXL]>24.5 mm)and non-myopic(21.0 mm 详细信息

Background:To investigate the decentration and tilt of plate-haptic multifocal intraocular lenses(MfIOLs)in myopic eyes.Methods:Myopic(axial length[AXL]>24.5 mm)and non-myopic(21.0 mmhe OPD-Scan III aberrometer 3 months postoperatively.Subjective symptoms were assessed with a Quality of Vision questionnaire.Results:Near and distance visual acuities,tilt and horizontal decentration did not differ between the two groups,postoperatively.However,myopic eyes of Group B showed greater vertical decentration than those of Group A(−0.17±0.14 mm vs.-0.03±0.09 mm,respectively),particularly when the MfIOLs were placed horizontally or obliquely.Overall decentration of myopic eyes was greater in Group B than in Group A(0.41±0.15 mm vs.0.16±0.10 mm,respectively).In Group B,AXL was negatively correlated with vertical decentration and positively correlated with overall decentration.No such correlations were found in Group A.Intraocular total HOAs,coma,trefoil and spherical aberrations were lower in Group A than in Group B for a 6.0 mm pupil among myopic eyes.Generally,Group A had better MTFs and fewer subjective symptoms than Group B among myopic eyes.Conclusions:Plate-haptic design of MfIOLs may be a suggested option for myopic cataract eyes due to the less inferior decentration and better visual quality postoperatively.

关键词： Decentration Tilt Multifocal intraocular lens High myopia Cataract surgery

Significant influences of TiO_(2)crystal structures on NO_(2)and HONO emissions from the nitrates photolysis

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Journal of Environmental Sciences 2021年第4期33卷 198-206页

作者： wenwen Xu Wangjin Yang Chong Han he Yang Xiangxin Xue School of Metallurgy Northeastern UniversityShenyang 110819China

The emissions of NO_(2)and HONO from the KNO_(3)photolysis in the presence of TiO_(2)were measured using a round-shape reactor coupled to a NO_(x)analyzer.TiO_(2)played important roles in the emission flux density of NO_(2)(R_(NO_(2)))and HONO(R HONO),depending on crystal structures and mass ratios of TiO_(2).R NO_(2)and R HONO significantly decreased with increasing the rutile and anatase mass ratios from 0 to 8 and 0.5 wt.%,respectively.Nevertheless,with further increasing the anatase mass ratio to 8 wt.%,there was an increase in R_(NO_(2))and R HONO.R NO_(2)on KNO_(3)/TiO_(2)/SiO_(2)had positive correlation with the KNO_(3)mass(1–20 wt.%),irradiation intensity(80–400 W/m^(2))and temperature(278–308 K),while it had the maximum value at the relative humidity(RH)of 55%.R HONO on KNO_(3)/TiO_(2)/SiO_(2)slightly varied with the KNO_(3)mass and temperature,whereas it increased with the irradiation intensity and RH.In addition,the mechanism for NO_(2)and HONO emissions from the nitrates photolysis and atmospheric implications were discussed.

关键词： TiO_(2) Nitrates Photolysis NO_(2)

Application of sequential extraction for analyzing source and sink of uranium in Huanghe River sediments,China

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Journal of Oceanology and Limnology 2023年第3期41卷 936-946页

作者： Xihuang ZHONG Xueyan JIANG Huijun he wenwen ZHANG Chunxia MENG Feng SUN Key Laboratory of Marine Chemistry Theory and Technology of Ministry of Education Ocean University of ChinaQingdao 266100China College of Chemistry and Chemical Engineering Ocean University of ChinaQingdao 266100China School of Materials Science and Engineering Ocean University of ChinaQingdao 266100China

Geochemical behaviors of heavy metals are closely related to their chemical state that can be divided by sequential extraction into exchangeable(F1),bound to carbonates(F2),bound to Fe-Mn oxides(F3),bound to organic matter or sulfide(F4),and residual(F5).Uranium in sediment of the Huanghe(Yellow)River,China,in different chemical states was extracted using the five-step procedure of Tessier and the source and sink were analyzed.Results show that more than 70%of the total uranium was immobile residual F5 in abundance,followed in order of F4>F3>F2>F1,indicating that the main source of uranium in the sediments was from weathered rock in the drainage basin.In addition,the uranium in the sediments presents potential exogenous input in the Lanzhou,Baotou,and Tongguan reach.Fe-Mn oxides are main carriers of unstable uranium,especially those of F1 and F3.Calcite and illite are secondary adsorption minerals of unstable uranium in sediments under natural conditions.Human activities can also produce an obvious impact on uranium speciation.This study provides a reference for the application of sequential extraction in analyzing the source and sink of uranium in river sediments.

关键词： uranium sequential extraction mineral composition sediment Huanghe(Yellow)River

Comparisons and Improvements of Key Operating Characteristics of Current Source Converter Applied in HVDC System

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CSEE Journal of Power and Energy Systems 2023年第5期9卷 1601-1612页

作者： wenwen Zhang Longlong Chen Xiaoguang Wei Guangfu Tang Lei Qi Chong Gao Zhiyuan he the North China Electric Power University Beijing 102206China the State Key Laboratory of Advanced Power Transmission Technology Beijing Institute Of Smart EnergyBeijing 102206China the State Grid Smart Grid Research Institute Co.Ltd Beijing 102209China

Because of its controlled power factor and no commutation failure,current source converter(CSC)made up of reverse-blocking IGCTs(RB-IGCTs)offers broad application prospects in the field of HVDC system.Valve voltage and power operating range as the most important operating characteristics should be paid attention to but they are always contradictory.First,the relationship between valve voltage and modulation index is obtained.In particular,valve voltage of converter under the three typical modulation methods is compared,analyzed,and verified.Second,with the help of the independent control strategy and coordinated control strategy of both ends,power operating ranges of the three modulation methods are comprehensively analyzed and compared.Third,in order to solve power coupling at a low active power,the improved coordination control strategy at both ends in this paper is proposed and the relationships among active power,reactive power,DC current and phase angle difference are given in detail.Finally,a 500 kV/3 kA simulation system was built in PSCAD/EMTDC to obtain comparison results of the key operating characteristics of CSC under different modulation methods and the converter can realize unity power operation under random active power after adopting the improved coordinated control strategy,and DC current does not decrease to zero,verifying effectiveness of the coordinated control strategy.

关键词： Current source converter improved coordinated control strategy reverse-blocking IGCT valve voltage