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Uncertainty and disturbance estimator-based model predictive control for wet flue gas desulphurization system

Chinese Journal of Chemical Engineering 2024年第3期67卷 182-194页

作者： shan Liu wenqi Zhong Li Sun Xi Chen Rafal Madonski School of Energy and Environment Key Laboratory of Energy Thermal Conversion and Control of Ministry of EducationSoutheast UniversityNanjing 210096China Faculty of Automatic Control Electronics and Computer ScienceSilesian University of TechnologyGliwise 44-100Poland

Wet flue gas desulphurization technology is widely used in the industrial process for its capability of efficient pollution removal.The desulphurization control system,however,is subjected to complex reaction mechanisms and severe disturbances,which make for it difficult to achieve certain practically relevant control goals including emission and economic performances as well as system robustness.To address these challenges,a new robust control scheme based on uncertainty and disturbance estimator(UDE)and model predictive control(MPC)is proposed in this paper.The UDE is used to estimate and dynamically compensate acting disturbances,whereas MPC is deployed for optimal feedback regulation of the resultant dynamics.By viewing the system nonlinearities and unknown dynamics as disturbances,the proposed control framework allows to locally treat the considered nonlinear plant as a linear one.The obtained simulation results confirm that the utilization of UDE makes the tracking error negligibly small,even in the presence of unmodeled dynamics.In the conducted comparison study,the introduced control scheme outperforms both the standard MPC and PID(proportional-integral-derivative)control strategies in terms of transient performance and robustness.Furthermore,the results reveal that a lowpass-filter time constant has a significant effect on the robustness and the convergence range of the tracking error.

关键词： Desulphurization system Disturbance rejection Model predictive control Uncertainty and disturbance estimator Nonlinear system

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Genetic structure of Aedes albopictus(Diptera:Culicidae)populations in China and relationship with the knockdown resistance mutations

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Infectious Diseases of Poverty 2023年第3期12卷 31-40页

作者： Wenqi Shan Hao Yuan Hanming Chen Haowei Dong Qiuming Zhou Feng Tao Jie Bai Huiying Chen Yajun Ma Heng Peng Department of Naval Medicine Naval Medical UniversityShanghai 200433China Department of Medical Microbiology and Parasitology College of Basic Medical SciencesNaval Medical UniversityShanghai 200433China

Background Mosquito control is needed to prevent dengue fever, which is mainly spread byAedes albopictus in China. Application of insecticides is one of the main mosquito control methods;however, this approach can fail due to the knockdown resistance (kdr) gene mutation that causes decreased sensitivity to insecticides inAe. albopictus. Thekdr mutation patterns among different regions in China differ significantly. However, the underlying mechanism and factors that influencekdr mutation remain unclear. To explore the potential influence of genetic background on the development of insecticide resistance inAe. albopictus, we analyzed the genetic structure ofAe. albopictus populations in China and its correlation with majorkdr mutations.Methods We collectedAe. albopictus from 17 sites in 11 provinces (municipalities) across China from 2016 to 2021 and extracted the genomic DNA from individual adult mosquitoes. We selected eight microsatellite loci for genotyping, and based on microsatellite scores, we estimated intraspecific genetic diversity, population structure, and effective population size. The association between the intrapopulation genetic variation and F1534 mutation rate was evaluated by the Pearson correlation coefficient.Results Based on variation analysis of the microsatellite loci of 453 mosquitoes representing 17 populations throughout China, more than 90% of the variation occurred within individuals, whereas only about 9% of the variation occurred among populations, indicating that field populations ofAe. albopictus are highly polymorphic. The northern populations tended to belong to gene pool I (BJFT 60.4%, SXXA 58.4%, SDJN 56.1%, SXYC 46.8%), the eastern populations tended to belong to pool III (SH 49.5%, JZHZ 48.1%), and the southern populations tended to belong to three different gene pools. Moreover, we observed that the greater the fixation index (FST), the lower the wild-type frequency of F1534 ofVSGC.Conclusions The degree of genetic differentiation amongAe. albopictus populations in China was

关键词： Aedes albopictus Population structure Microsatellite Knockdown resistance China

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Carboniferous integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1071-1106页

作者： Keyi HU Xiangdong WANG wenqi WANG Yingfan SONG Xunyan YE Lu LI Yukun SHI Sunrong YANG Ying LI State Key Laboratory for Mineral Deposits Research School of Earth Sciences and Engineering and Frontiers Science Center for Critical Earth Material CyclingNanjing UniversityNanjing 210023China

During the Carboniferous Period,the Qinghai-Tibetan Plateau and its surrounding areas were located in quite different paleogeographic positions with various sedimentary and biological types.It is important to systematically compile and summarize the Carboniferous strata and biotas of the Qinghai-Tibetan Plateau and its surrounding areas,to establish an integrated stratigraphic framework for correlation,and to reconstruct the paleogeography for correctly understanding the breakup of the Gondwana Continent and the evolution of the Paleo-Tethys Ocean in the Late Paleozoic.The Carboniferous of the Qinghai-Tibetan Plateau and its surrounding areas can be subdivided into the Gondwanan,Cimmerian,and Tethyan types.The Gondwanan-type Carboniferous are distributed in the North Himalayan,Kangmar-Lhunze,and Zanda-Zumba regions of the South Tibet Subprovince and northern India-Pakistan Area,where only the Mississippian is developed and the biota is of Gondwanan affinity.The Cimmerian-type Carboniferous,which are found in the Baoshan,Tengchong,Coqen-Xainza,LhasaZayu,Nagqu-Biru,and South Qiangtang regions,as well as shan-Thai and South Afghanistan-Pamir areas,also represent only the Mississippian strata,but their biota is characterized by mixed characters of European,South China,Australian,and North American types.The Tethyan-type Carboniferous are distributed in the Tanggula Mountains,Hoh Xil-Bayanhar,ChamdoHengduanshan,Tiekelike,West Kunlun,Karakorum,East Kunlun-Central Qinling,and Qilian regions,where the Carboniferous succession is well developed,and the biota is of warm-water Tethyan affinity.The biostratigraphical correlation of the Gondwanan-type and Cimmerian-type Carboniferous is based mainly on conodonts and additionally on brachiopods and rugose corals.The Mississippian of the Tethyan-type Carboniferous is correlated mainly by using rugose corals and brachiopods,whereas in the Pennsylvanian foraminifera(fusuline)and conodonts are regarded as primary fossil groups,subordinated by rugose corals and brachiopods.Adhering

关键词： Qinghai-Tibetan Plateau Carboniferous Lithostratigraphy Biota Stratigraphic correlation

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基于LSMR算法的火焰三维温度场重建

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化工进展 2024年第2期43卷 659-666页

作者：单良仰文淇洪波周荣幸孔明中国计量大学信息工程学院浙江省电磁波信息技术与计量检测重点实验室浙江杭州310018 中国计量大学计量测试工程学院浙江杭州310018

光场成像技术可以同时记录入射光线的空间分布信息和传播方向信息,结合相关反演算法,可以进行火焰三维温度场的重建。最小二乘QR分解算法(least squares via QR factorization,LSQR)可以有效求解基于大型稀疏矩阵的线性问题,但是在对火... 详细信息

光场成像技术可以同时记录入射光线的空间分布信息和传播方向信息,结合相关反演算法,可以进行火焰三维温度场的重建。最小二乘QR分解算法(least squares via QR factorization,LSQR)可以有效求解基于大型稀疏矩阵的线性问题,但是在对火焰辐射强度求解的过程中,难以保证求解的非负性和准确性。非负最小二乘算法(non-negative least squares,NNLS)可以保证求解的非负性,但是计算效率太低。本文提出将最小二乘残差方法(least square minimal residual,LSMR)用于火焰光场成像三维温度场重建,并研究其重建精度、计算效率、抗噪性能等指标。仿真实验表明,LSMR和NNLS算法可以在不同噪声水平下保证求解火焰辐射强度的非负性。在噪声为5%、10%、15%和20%的情况下,LSMR和NNLS算法对辐射强度的求解精度均比LSQR提高了10%以上,且LSMR算法的求解时间比LSQR和NNLS分别降低了一个数量级和四个数量级。可见,LSMR算法可以在保证求解精度的情况下大幅提高运算效率。最后用LSMR算法对模拟光场火焰进行温度场重建,在不同噪声水平下,平均相对误差都保持在1.2%以内,验证了LSMR算法在重建时的准确性和可靠性。

关键词：光场成像火焰 LSMR算法三维温度场重建

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基于注意力机制的改进残差网络火焰温度场重建

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化工进展 2024年第2期43卷 688-695页

作者：单良周荣幸洪波仰文淇孔明中国计量大学信息工程学院浙江省电磁波信息技术与计量检测重点实验室浙江杭州310018 中国计量大学计量测试工程学院浙江杭州310018

基于卷积神经网络重建火焰温度场的方法近年来已被广泛采用,但是传统卷积神经网络模型随着其网络层数的增加极易出现过拟合或者模型退化的现象,导致重建误差较大。本文提出一种改进的方法,使用ResNet18网络进行火焰温度场重建,并引入注... 详细信息

基于卷积神经网络重建火焰温度场的方法近年来已被广泛采用,但是传统卷积神经网络模型随着其网络层数的增加极易出现过拟合或者模型退化的现象,导致重建误差较大。本文提出一种改进的方法,使用ResNet18网络进行火焰温度场重建,并引入注意力机制和局部重要性池化,优化提取内容,实现已知信息的充分利用,减少重建误差。实验结果表明,同时引入局部重要性池化和注意力机制后,温度场重建的平均相对误差为0.13%,最大相对误差为0.75%;相较于初始ResNet18网络,平均相对误差减少了31.58%,最大相对误差减少了34.21%。通过消融实验验证了两种因素对重建精度的影响,结果表明:同时加入两个改进模块后的温度场重建精度要优于加入单个改进模块后的精度,局部重要性池化模块对精度提升的作用更大。

关键词：温度场残差网络注意力机制池化

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Integrative Carboniferous stratigraphy, biotas and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年

During the Carboniferous Period, the Qinghai-Tibetan Plateau and its surrounding areas were located in quite different paleogeographic positions with various sedimentary and biological types. It is important to systematically compile and summarize the Carboniferous strata and biotas of the Qinghai-Tibetan Plateau and its surrounding areas, to establish an integrated stratigraphic framework for correlation, and to reconstruct the paleogeography for correctly understanding the breakup of the Gondwana Continent and the evolution of the Paleo-Tethys Ocean in the Late Paleozoic. The Carboniferous of the Qinghai-Tibetan Plateau and its surrounding areas can be subdivided into the Gondwanan, Cimmerian, and Tethyan types. The Gondwanan-type Carboniferous are distributed in the North Himalayan, Kangmar-Lhunze, and Zanda-Zumba regions of the South Tibet Subprovince and northern India-Pakistan Area, where only the Mississippian is developed and the biota is of Gondwanan affinity. The Cimmerian-type Carboniferous, which are found in the Baoshan, Tengchong, Coqen-Xainza, LhasaZayu, Nagqu-Biru, and South Qiangtang regions, as well as shan-Thai and South Afghanistan-Pamir areas, also represent only the Mississippian strata, but their biota is characterized by mixed characters of European, South China, Australian, and North American types. The Tethyan-type Carboniferous are distributed in the Tanggula Mountains, Hoh Xil-Bayanhar, ChamdoHengduanshan, Tiekelike, West Kunlun, Karakorum, East Kunlun-Central Qinling, and Qilian regions, where the Carboniferous succession is well developed, and the biota is of warm-water Tethyan affinity. The biostratigraphical correlation of the Gondwanan-type and Cimmerian-type Carboniferous is based mainly on conodonts and additionally on brachiopods and rugose corals. The Mississippian of the Tethyan-type Carboniferous is correlated mainly by using rugose corals and brachiopods,whereas in the Pennsylvanian foraminifera(fusuline) and conodonts are regarded as primary fossil groups, subordinated by

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从功德报偿到“汉家尧后”:刘邦置立巫官与两汉天命论的变迁

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复旦学报（社会科学版） 2024年第1期66卷 12-22页

作者：尉雯琪清华大学历史系北京100084

据《封禅书》,刘邦曾经置立巫官。其中梁、晋、秦、荆四者,无论以刘邦祭祖、神权统一还是抚慰诸侯作解,都存在一定问题。通过对秦汉之际战争中巫术需求的考察,以及刘邦军队士卒来源的梳理,可以发现刘邦于征战之中,招徕收附的兵丁籍贯正... 详细信息

据《封禅书》,刘邦曾经置立巫官。其中梁、晋、秦、荆四者,无论以刘邦祭祖、神权统一还是抚慰诸侯作解,都存在一定问题。通过对秦汉之际战争中巫术需求的考察,以及刘邦军队士卒来源的梳理,可以发现刘邦于征战之中,招徕收附的兵丁籍贯正与诸巫相合。刘邦置立诸巫的初衷,与时人功德报偿的观念有关。《汉书》因其中四巫合于刘向所述汉家先祖的迁徙轨迹,遂作割裂剪裁,以为“汉家尧后”之证。这合于东汉明章两朝的时势,也显示出两汉天命论由朴素直接、含混笼统,渐为文饰堂皇、具体指实的变迁。

关键词：刘邦巫官天命《封禅书》班固 “汉家尧后”

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Multiobjective economic model predictive control using utopia-tracking for the wet flue gas desulphurization system

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Chinese Journal of Chemical Engineering 2023年第2期54卷 343-352页

作者： shan Liu wenqi Zhong Xi Chen Li Sun Lukuan Yang Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjing 210096China

Efficient control of the desulphurization system is challenging in maximizing the economic objective while reducing the SO_(2) emission concentration. The conventional optimization method is generally based on a hierarchical structure in which the upper optimization layer calculates the steady-state results and the lower control layer is responsible to drive the process to the target point. However, the conventional hierarchical structure does not take the economic performance of the dynamic tracking process into account. To this end, multi-objective economic model predictive control(MOEMPC) is introduced in this paper, which unifies the optimization and control layers in a single stage. The objective functions are formulated in terms of a dynamic horizon and to balance the stability and economic performance. In the MOEMPC scheme, economic performance and SO_(2) emission performance are guaranteed by tracking a set of utopia points during dynamic transitions. The terminal penalty function and stabilizing constraint conditions are designed to ensure the stability of the system. Finally, an optimized control method for the stable operation of the complex desulfurization system has been established. Simulation results demonstrate that MOEMPC is superior over another control strategy in terms of economic performance and emission reduction, especially when the desulphurization system suffers from frequent flue gas disturbances.

关键词： Desulphurization system Economics Economic model predictive control Flue gas Optimization Utopia point

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氯菊酯对人小胶质细胞HMC3的毒性效应及潜在机制

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环境与职业医学 2024年第3期41卷 267-275页

作者：张婉莉单文琪陈超董昊炜袁浩周秋明陶峰彭恒马雅军海军军医大学海军医学系上海200433 海军军医大学基础医学院上海200433

[背景]氯菊酯是一种常用的拟除虫菊酯类杀虫剂,研究发现其具有潜在神经系统毒性。小胶质细胞是中枢神经系统中的天然免疫细胞,参与一系列神经退行性疾病的发生。[目的]本研究观察氯菊酯在体外对人小胶质细胞HMC3的毒性效应,并探讨其机制... 详细信息

[背景]氯菊酯是一种常用的拟除虫菊酯类杀虫剂,研究发现其具有潜在神经系统毒性。小胶质细胞是中枢神经系统中的天然免疫细胞,参与一系列神经退行性疾病的发生。[目的]本研究观察氯菊酯在体外对人小胶质细胞HMC3的毒性效应,并探讨其机制。[方法]使用0、10、25、55μmol·L^(-1)的氯菊酯染毒HMC372 h后,使用流式细胞仪检测细胞周期和细胞凋亡,实时荧光定量PCR(qPCR)检测细胞周期蛋白依赖性激酶1基因(CDK1)、细胞周期蛋白依赖性激酶抑制因子1A基因(CDKN1A)、细胞周期蛋白B2基因(CCNB2)、肿瘤蛋白p53基因(p53)、凋亡相关因子基因(FAS)、胱天蛋白酶3基因(CASP3)和H2A变体组蛋白基因(H2AX)的表达。转录组测序(RNA-seq)检测0、25μmol·L^(-1)氯菊酯染毒后HMC3的差异基因和富集通路。再次使用0、10、25、55μmol·L^(-1)的氯菊酯染毒HMC372 h后,使用格里斯试剂法检测上清中一氧化氮(NO)含量,酶联免疫吸附法检测白细胞介素(IL)-6的分泌水平,qPCR检测丝裂原活化蛋白激酶(MAPK)通路(包括MAPK1、MAPK8、MAPK14)、IL-1β、IL-6和基质金属蛋白酶(MMP)家族(包括MMP1、MMP2、MMP3和MMP9)的m RNA表达情况,蛋白质印记法(Western blot)检测磷酸化p38(p-p38)、磷酸化细胞外信号调节激酶(p-ERK)、IL-1β、IL-6和MMP1蛋白表达情况。[结果]0、10、25、55μmol·L^(-1)氯菊酯染毒细胞后,HMC3在G2/M期阻滞,其中55μmol·L^(-1)氯菊酯染毒组与对照组差异有统计学意义(P0.05)。RNA-seq结果提示差异基因富集于MAPK通路。q PCR结果提示55μmol·L^(-1)染毒组MAPK1、MAPK8和MAPK14的m RNA表达较对照组上调(P<0.05)。Western blot发现,与对照组相比,10μmol·L^(-1)氯菊酯染毒组的p-p38和p-ERK水平均升高(P<0.05),25μmol·L^(-1)氯菊酯染毒组的p-ERK水平升高(P<0.05),55μmol·L^(-1)氯菊酯染毒组的p-p38水平升高(P<0.05)。与对照组相比,染毒后的HMC3上清液中NO分泌量增加(P<0.05),IL-6的m RNA、蛋白表达和分泌量呈上升趋势,IL-1β的mRNA和蛋白表达上调(P<0.05),25、55μmol·L^(-1)组MMP1的m RNA和蛋白表达上调(P<0.05)。[结论]氯菊酯在体外抑制HMC3细胞增殖,诱导细胞周期阻滞,可激活MAPK通路,促进炎症因子IL-1β以及MMP1表达,可能是氯菊酯致人神经毒性的机制之一。

关键词：氯菊酯小胶质细胞白细胞介素-1β 基质金属蛋白酶丝裂原活化蛋白激酶炎症反应

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基于环介导等温扩增微流控芯片技术快速检测蚊媒携带登革病毒方法的建立

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中国寄生虫学与寄生虫病杂志 2024年第2期42卷 234-241页

作者：姜宁白洁李平单文琪周秋明董昊炜袁浩陶峰李翔宇马雅军彭恒上海理工大学健康科学与工程学院上海200093 中国人民解放军海军军医大学基础医学院病原生物学教研室上海200433 海口市疾病预防控制中心海南海口571100 中国人民解放军海军军医大学海医系上海200433

目的建立一种基于环介导等温扩增(LAMP)微流控芯片技术的快速检测蚊媒携带登革病毒的方法。方法根据登革病毒衣壳蛋白(C)、前膜蛋白(prM)和非结构蛋白2A(NS2A)基因片段构建pUC-GWAmp-CprM和pUC-GW-Amp-NS2A质粒,设计多组环介导等温扩增... 详细信息

目的建立一种基于环介导等温扩增(LAMP)微流控芯片技术的快速检测蚊媒携带登革病毒的方法。方法根据登革病毒衣壳蛋白(C)、前膜蛋白(prM)和非结构蛋白2A(NS2A)基因片段构建pUC-GWAmp-CprM和pUC-GW-Amp-NS2A质粒,设计多组环介导等温扩增特异性引物组。制备LAMP微流控芯片,以靶基因质粒、登革病毒核酸为模板进行检测,根据起峰时间、相对荧光单位、假阳性、重复实验稳定性、检测灵敏度等指标筛选最优引物组。用最优引物组分别检测埃及伊蚊、白纹伊蚊等主要登革热传播媒介和常见的致倦库蚊、中华按蚊、摇蚊的cDNA,并与寨卡病毒、流行性乙型脑炎病毒、恶性疟原虫、黄热病毒等常见蚊媒传播病原体进行交叉检测,评价LAMP法的特异性。评价LAMP法检测CprM和NS2A靶基因质粒的灵敏度,分别与PCR、实时荧光定量PCR(qPCR)检测结果进行比较。用登革病毒RNA与传播媒介埃及伊蚊、白纹伊蚊RNA分别以1∶10、1∶100和1∶1000混合,模拟媒介携带登革病毒的样品进行LAMP微流控芯片检测。对采集自宁德市三都岛、西安市、上海朱家角、长兴岛和五角场等5地的白纹伊蚊的cDNA进行检测。结果引物组筛选结果显示,CprMG2和NS2AG1引物组起峰时间早,相对荧光单位高,灵敏度最高,为最优引物组。CprMG2引物组可检测浓度低至10-6 ng/μl的pUC-GW-Amp-CprM质粒,最低检测限为1.3×10^(3)拷贝;NS2AG1引物组可检测浓度低至10-9 ng/μl的pUC-GW-Amp-NS2A质粒,最低检测限为1拷贝。最优引物组CprMG2、NS2AG1对埃及伊蚊、白纹伊蚊、中华按蚊、致倦库蚊、摇蚊等蚊虫cDNA无非特异性扩增,与寨卡病毒、流行性乙型脑炎病毒、恶性疟原虫、黄热病毒核酸无交叉反应。LAMP微流控芯片检测CprM靶基因的最低检测限为1.3×10^(3)拷贝,较PCR检测的最低检测限(1.3×10^(4)拷贝)高1个数量级;LAMP微流控芯片检测CprM和NS2A靶基因的最低检测限分别为1.3×10^(3)拷贝、1拷贝,与qPCR检测的最低检测限(1.3×10^(3)拷贝、1拷贝)相当。LAMP微流控芯片检测模拟现场样品的结果显示,CprMG2可检出与埃及伊蚊、白纹伊蚊RNA 1∶10、1∶100和1∶1000混合的登革病毒RNA,NS2AG1最低可检出1∶100混合的登革病毒,特异性均为100%。LAMP微流控芯片检测5地现场采集白纹伊蚊的结果均为阴性。结论建立了基于LAMP微流控芯片检测登革病毒的方法,该法敏感性和特异性高,检测时间短,可用于现场蚊媒携带登革病毒的检测。

关键词：登革病毒蚊虫环介导等温扩增微流控芯片现场检测技术

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