检索结果-南通市图书馆

Particuology 2024年第5期88卷 210-217页

作者： Yuanting Wu Xiaoying Wang wenlong zhong Shan Zhang School of Material Science and Engineering Shaanxi University of Science and TechnologyXi'an 710021China

Heterogeneous photocatalysts exhibit high catalytic efficiency in the degradation of pollutants,but their stability and repeatability is not very good and requires high structural matching.Simply by nanosizing the pure Bi 2 WO6(BWO)photocatalyst without constructing a heterojunction,there is a significant improvement in its performance,with an enhancement effect of about 2.3 times(99.43%).The high photocatalytic degradation efficiency of the material can be attributed to the enhanced light absorption effect brought by the three-dimensional inverse-opal structure SiO 2(IS)and the abundant surface adsorbed oxygen generated after the formation of Si–O–W bonds.In addition,the introduction of IS greatly increases the surface area of nanostructured BWO,which accelerates the charge transfer process,while the adsorbed oxygen promotes the participation of·O2−in the photocatalytic reaction,thereby accelerating the consumption of photo-generated electrons and ultimately improving the separation of charge carriers.Furthermore,the matched photonic bandgap further improves the absorption and utilization of light of the material.In this work,we constructs Si–O–W bonds to obtain inverse-opal SiO2/Bi2 WO6 with uniformly growth of pure phase nano BWO,which provides a feasible strategy for the preparation of high-performance pure-phase photocatalysts.

关键词： Bi2WO6 SiO2 inverse-opal structure Photocatalysis Adsorbed oxygen

The activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions:insights from a single-arm,phase II trial

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第5期9卷 2202-2214页

作者： Bo Cheng Caichen Li Jianfu Li Longlong Gong Peng Liang Ying Chen Shuting Zhan Shan Xiong Ran zhong Hengrui Liang Yi Feng Runchen Wang Haixuan Wang Hongbo Zheng Jun Liu Chengzhi Zhou wenlong Shao Yuan Qiu Jiancong Sun Zhanhong Xie Zhu Liang Chenglin Yang Xiuyu Cai Chunxia Su Wei Wang Jianxing He Wenhua Liang Department of Thoracic Surgery and Oncology the First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou Institute of Respiratory HealthState Key Laboratory of Respiratory DiseaseNational Clinical Research Center for Respiratory DiseaseGuangzhouChina Medical Department Genecast Biotechnology Co.LtdWuxiChina Department of Radiation Oncology the First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouChina Department of Respiratory Medicine the First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou Institute of Respiratory HealthState Key Laboratory of Respiratory DiseaseNational Clinical Research Center for Respiratory DiseaseGuangzhouChina Department of Cardiothoracic Surgery Affiliated Hospital of Guangdong Medical UniversityZhanjiangChina Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeShenzhenChina Department of VIP Inpatient Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaSun Yat-sen UniversityGuangzhouChina Department of Medical Oncology Shanghai Pulmonary HospitalSchool of MedicineTongji UniversityShanghaiChina

Immune checkpoint inhibitors targeting the programmed cell death-1(PD-1)protein significantly improve survival in patients with advanced non-small-cell lung cancer(NSCLC),but its impact on early-stage ground-glass opacity(GGO)lesions remains unclear.This is a single-arm,phase II trial(NCT04026841)using Simon’s optimal two-stage design,of which 4 doses of sintilimab(200 mg per 3 weeks)were administrated in 36 enrolled multiple primary lung cancer(MPLC)patients with persistent high-risk(Lung-RADS category 4 or had progressed within 6 months)GGOs.The primary endpoint was objective response rate(ORR).T/B/NK-cell subpopulations,TCR-seq,cytokines,exosomal RNA,and multiplexed immunohistochemistry(mIHC)were monitored and compared between responders and non-responders.Finally,two intent-to-treat(ITT)lesions(pure-GGO or GGO-predominant)showed responses(ORR:5.6%,2/36),and no patients had progressive disease(PD).No grade 3-5 TRAEs occurred.The total response rate considering two ITT lesions and three non-intent-to-treat(NITT)lesions(pure-solid or solid-predominant)was 13.9%(5/36).The proportion of CD8^(+)T cells,the ratio of CD8^(+)/CD4^(+),and the TCR clonality value were significantly higher in the peripheral blood of responders before treatment and decreased over time.Correspondingly,the mIHC analysis showed more CD8^(+)T cells infiltrated in responders.Besides,responders’cytokine concentrations of EGF and CTLA-4 increased during treatment.The exosomal expression of fatty acid metabolism and oxidative phosphorylation gene signatures were down-regulated among responders.Collectively,PD-1 inhibitor showed certain activity on high-risk pulmonary GGO lesions without safety concerns.Such effects were associated with specific T-cell re-distribution,EGF/CTLA-4 cytokine compensation,and regulation of metabolism pathways.

关键词： lesions metabolism doses

棉籽蛋白的加工工艺与营养成分及其在猪生产中的应用研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

动物营养学报 2024年第4期36卷 2175-2187页

作者：仲文龙朱元召王丽李平广东省农业科学院动物科学研究所猪禽种业全国重点实验室农业农村部华南动物营养与饲料重点实验室广东省畜禽育种与营养研究重点实验室岭南现代农业科学与技术广东省实验室茂名分中心广州510640 安徽科技学院动物科学学院滁州233100

我国是饲料生产大国,配合饲料产量位居世界第一,但豆粕等重要的蛋白质饲料原料在很大程度上依赖于进口,所以开发可替代豆粕的高品质蛋白质饲料原料尤为重要。我国棉花资源丰富,棉花加工过程中的副产物棉籽粕富含蛋白质和氨基酸,由棉籽... 详细信息

我国是饲料生产大国,配合饲料产量位居世界第一,但豆粕等重要的蛋白质饲料原料在很大程度上依赖于进口,所以开发可替代豆粕的高品质蛋白质饲料原料尤为重要。我国棉花资源丰富,棉花加工过程中的副产物棉籽粕富含蛋白质和氨基酸,由棉籽粕进一步加工处理得到的棉籽蛋白,粗蛋白质含量高、氨基酸较平衡,可以在一定程度上替代豆粕和降低饲料成本。本文总结了棉籽蛋白的分类、加工工艺、营养成分、猪的有效能和氨基酸消化率及其在猪生产中的应用研究,可为棉籽蛋白的深层次开发和高效利用提供参考。

关键词：棉籽蛋白加工工艺营养成分猪研究进展

在线全文

学校读者我要写书评

暂无评论

儿童中猴痘病毒传播特点及防治研究进展

中华儿科杂志 2024年第1期62卷 87-90页

作者：张超阴怀清阴崇娟张瑞元钟亚婧牛冰宇张文龙山西医科大学第一临床医学院太原030001 山西医科大学第一医院儿科太原030001 山西医科大学儿科医学系太原030001

猴痘是由猴痘病毒引起的人畜共患病。儿童属于猴痘病毒感染高危人群,在猴痘病毒的传播途径、防疫及治疗中与成人存在区别应该引起注意。现对儿童猴痘病毒历史感染情况归纳分析并综述,当前全球猴痘疫苗与抗病毒药物研究进展,旨在为儿童... 详细信息

猴痘是由猴痘病毒引起的人畜共患病。儿童属于猴痘病毒感染高危人群,在猴痘病毒的传播途径、防疫及治疗中与成人存在区别应该引起注意。现对儿童猴痘病毒历史感染情况归纳分析并综述,当前全球猴痘疫苗与抗病毒药物研究进展,旨在为儿童猴痘病毒感染管理与研究提供参考。

关键词：人畜共患病猴痘病毒药物研究进展传播途径归纳分析抗病毒高危人群

在线全文

学校读者我要写书评

暂无评论

基于以情胜情理论探讨分离障碍治疗

光明中医 2024年第12期39卷 2485-2487页

作者：钟慧芳郭文龙湖南中医药大学湖南长沙410208 湖南中医药大学附属省直中医医院急危重症医学中心湖南株洲412000

分离障碍,又称癔症,是一种急诊科常见的心理疾病,因发作时表现类似急症,常被当作急危重症送往急诊科治疗。此病常由长期不良心态和强烈且过度的精神刺激诱发。这种精神上有害的刺激破坏了脏腑间和身体内外的相对平衡状态,使脏腑阴阳气... 详细信息

分离障碍,又称癔症,是一种急诊科常见的心理疾病,因发作时表现类似急症,常被当作急危重症送往急诊科治疗。此病常由长期不良心态和强烈且过度的精神刺激诱发。这种精神上有害的刺激破坏了脏腑间和身体内外的相对平衡状态,使脏腑阴阳气血失调而致病。西医以对症支持治疗为主,效果一般,中医在此病的治疗上方法多样。文章基于“以情胜情”理论探讨分离障碍的治疗,旨在为分离障碍的治疗提供新思路。

关键词：郁证癔症分离障碍以情胜情情志疗法

Mechanics of 2D material bubbles

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第12期16卷 13434-13449页

作者： Xuwei Cui Luqi Liu wenlong Dong Yekai Zhou zhong Zhang Chinese Academy of Sciences(CAS)Key Laboratory of Nanosystem and Hierarchical Fabrication and CAS Center for Excellence in Nanoscience National Center for Nanoscience and TechnologyBeijing 100190China CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230027China University of Chinese Academy of Sciences Beijing 100049China

A variety of out-of-plane deformation patterns have been observed for two-dimensional(2D)materials including ripples,wrinkles,buckles,scrolls,folds,tents,and bubbles due to their extra-low bending rigidity.Among them,the micro-and nanoscale bubbles arising from the deformation of the atomically thin membrane by gases,liquids,and solids trapped underneath 2D materials were frequently observed.On the one hand,the presence of bubbles may severely deteriorate the performance of 2D material devices because of the obstructed charge,photon,and phonon transport across the interface.On the other hand,these bubbles offer a novel avenue to explore the intrinsic mechanical parameters(e.g.,Young’s modulus and bending rigidity)of 2D materials as well as their interfacial properties(e.g.,shear stress and adhesion energy).Furthermore,these bubbles with stable and controllable morphology also act as effective knobs to tune the electronic and photonic performance of various 2D materials.This review highlights the recent progress on the 2D material bubbles,which will be helpful for measurement of the mechanical properties of ultrathin 2D materials and the applications of developing 2D material devices.

关键词： two-dimensional(2D)materials bubbles mechanics interface strain engineering

陆军空中突击部队索降训练伤现状及影响因素分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

陆军军医大学学报 2024年第1期46卷 53-57页

作者：苟文隆李殿威路星辰刘星邱金龙王钟王子明刘鹏陆军特色医学中心骨科重庆400042 陆军军医大学(第三军医大学)第一附属医院运动医学中心重庆400038 陆军特色医学中心军事交通伤防治研究室重庆400042 陆军特色医学中心陆军军事训练伤防治指导中心重庆400042

目的调查分析陆军空中突击部队索降训练伤的发生情况及危险因素,为训练伤的防控提供依据。方法本研究采用病例-对照研究设计方案,于2022年9月对某部官兵进行训练伤问卷调查。统计索降训练伤的发生情况及特点,根据是否存在训练伤将被试... 详细信息

目的调查分析陆军空中突击部队索降训练伤的发生情况及危险因素,为训练伤的防控提供依据。方法本研究采用病例-对照研究设计方案,于2022年9月对某部官兵进行训练伤问卷调查。统计索降训练伤的发生情况及特点,根据是否存在训练伤将被试者分为训练伤组与对照组。从两组被试者一般情况、身体素质、训练前受伤及训练后受伤情况等方面分析索降训练伤的危险因素。结果本研究纳入数据分析303例,其中索降训练伤发生115例(训练伤组,37.95%),对照组188例。训练伤高发部位依次为踝关节(19.72%)、膝关节(15.49%)和腕关节(13.15%)。Logistic回归分析显示军龄(95%CI:1.011~1.209,P=0.028)、独生子(95%CI:1.541~4.578,P=0.000)、仰卧起坐成绩(95%CI:0.922~0.970,P=0.000)和3000 m跑成绩(95%CI:1.001~1.010,P=0.029)是索降训练伤发生的独立危险因素。结论独生子、核心肌力和有氧耐力不足以及较年长的空中突击部队官兵更易发生索降训练伤。

关键词：空中突击部队索降军事训练伤危险因素

基于静电纺PVDF/GO复合纳米纤维的摩擦纳米发电机的制备和输出性能

在线全文

学校读者我要写书评

暂无评论

东华大学学报（自然科学版） 2024年第3期50卷 15-22页

作者：钟笑江李文龙高兴姚广春雒万代阳西安工程大学机电工程学院陕西西安

为提高基于聚偏氟乙烯(PVDF)的摩擦纳米发电机(TENG)的输出性能,采用静电纺丝法制备PVDF/GO(氧化石墨烯)复合纳米纤维,并组装成垂直接触-分离式TENG,探究GO质量分数对由PVDF/GO复合纳米纤维组成的TENG的输出性能的影响。通过COMSOL软件... 详细信息

为提高基于聚偏氟乙烯(PVDF)的摩擦纳米发电机(TENG)的输出性能,采用静电纺丝法制备PVDF/GO(氧化石墨烯)复合纳米纤维,并组装成垂直接触-分离式TENG,探究GO质量分数对由PVDF/GO复合纳米纤维组成的TENG的输出性能的影响。通过COMSOL软件对TENG的输出性能进行模拟仿真,分析TENG在不同极板距离下的电势和电能密度的变化规律,为TENG的工作原理提供理论支撑。通过扫描电子显微镜对PVDF/GO复合纳米纤维的形貌结构进行表征,并采用数字示波器对基于PVDF/GO复合纳米纤维的TENG的输出性能进行表征。结果表明:当GO质量分数为0.06%时,基于PVDF/GO复合纳米纤维的TENG具有良好的输出效率,其输出电压约为350 V,短路电流约为28μA,在阻抗匹配条件下,最大峰值功率约为9.66 mW,其功率密度约为3.86 W/m2。基于PVDF/GO复合纳米纤维制备的TENG具有良好的输出性能,能为120个发光二极管(LED)供电,因此在能量收集领域具有潜在的应用前景。

关键词：摩擦纳米发电机静电纺丝聚偏氟乙烯氧化石墨烯输出性能

褪黑素治疗新生儿缺氧缺血性脑病有效性的系统评价和Meta分析

在线全文

学校读者我要写书评

暂无评论

中华新生儿科杂志（中英文） 2024年第4期39卷 229-235页

作者：张超阴怀清阴崇娟张文龙钟亚婧师睿山西医科大学第一临床医学院山西医科大学第一医院儿科太原030001

目的系统评价褪黑素治疗新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)的临床疗效。方法计算机检索PubMed、Web of Science、Cochrane library、Embase、中华医学期刊全文数据库、中国知网、万方数据库、维普数据库自建库... 详细信息

目的系统评价褪黑素治疗新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)的临床疗效。方法计算机检索PubMed、Web of Science、Cochrane library、Embase、中华医学期刊全文数据库、中国知网、万方数据库、维普数据库自建库至2022年12月1日收录的以褪黑素作为干预手段治疗HIE的国内及国外公开发表的临床随机对照试验(randomized controlled trial,RCT)和队列研究。应用R4.2.2软件和RevMan5.4软件进行Meta分析、文献风险评估以及敏感性分析。结果共纳入有效RCT 4项,患儿155例。Meta分析结果显示,应用褪黑素可以降低HIE患儿病死率(RR=0.336,95%CI 0.157~0.718,P=0.005),应用褪黑素后HIE患儿血白细胞计数降低(MD=-1.741,95%CI-3.404~-0.079,P=0.040)。敏感性分析结果显示,逐一剔除各项研究后,Meta分析结果基本稳定。结论现有研究证据表明,褪黑素治疗可降低HIE患儿病死率,但因纳入研究的风险偏倚较大,样本量偏小,仍需更多高质量的研究作为循证依据。

关键词：缺氧缺血性脑病褪黑素新生儿 Meta分析治疗

Preparation and characterization of M_(1)-N_(x)-C_(y)based single atom catalysts for environmental applications

在线全文

学校读者我要写书评

暂无评论

中国化学快报:英文版 2023年第8期34卷 130-141页

作者： Xinjiang Hu Daixi Zhou Hui Wang wenlong Zhang Haoxiang zhong Yongsheng Chen College of Environmental Science and Engineering Central South University of Forestry and TechnologyChangsha 410004China School of Civil and Environmental Engineering Georgia Institute of TechnologyAtlantaGA 30332United States Georgia Tech Shenzhen Institute Tianjin UniversityShenzhen 518067China

Single atom catalysts(SACs)have become the frontier research fields in catalysis.The M_(1)-N_(x)-C_(y)based SACs,wherein single metal atoms(M1)are stabilized by N-doped carbonaceous materials,have provided new opportunities for catalysis due to their high reactivity,maximized atomic utilization,and high selectivity.In this review,the fabrication methods of M_(1)-N_(x)-C_(y)based SACs via support anchoring strategy and coordination design strategy are summarized to help the readers understand the interaction mechanism of single atoms and support.Then,characterization technologies for identifying single metal atoms are presented.Besides,the environmental applications including management of harmful gases,water purification are discussed.Finally,future opportunities and challenges for preparation strategies,mechanisms and applications are concluded.We conclude this review by emphasizing the fact that M_(1)-N_(x)-C_(y)based SACs has the potential to become an important candidate for solving current and future environmental pollution problems.

关键词： Single atom catalysts Photocatalysis Electrocatalysis Environmental applications