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Riverine sulfate sources and behaviors in arid environment,Northwest China:Constraints from sulfur and oxygen isotopes

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Journal of Environmental Sciences 2024年第3期137卷 716-731页

作者： Yifu Xu wenjing Liu Bing Xu Zhifang Xu Key Laboratory of Cenozoic Geology and Environment Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Innovation Academy for Earth Science Chinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China

The fate of riverine sulfate ion (SO_(4)^(2-)) and its environmental effects in arid environment are difficult to evaluate due to its complicated sources and strongly coupled behaviors with water cycle which is significantly modified by *** understand the sulfur cycle in aquatic systems in arid environment,the chemical and sulfur and oxygen isotopic compositions (δ^(34)S_(SO4)and δ^(18)O_(SO4)) of major rivers around the Badain Jaran Desert,northwestern China,were *** rivers had averaged SO_(4)^(2-)content at 1336μmol/L,over 10times higher than the global *** δ^(34)S_(SO4)and δ^(18)O_(SO4)values ranged from-5.3‰to+11.8‰and+1.6‰to+12.8‰,*** end-member analysis and the inverse model showed that riverine sulfate was mainly derived from evaporites dissolution (0-87%),sulfide oxidation (13%-100%) and precipitation (0-33%),indicating heterogeneity in sulfur sources and behaviors along the river drainage with the lithology variations and climate *** isotopic tools combining with hydro-chemistry compositions could be applied to reveal sulfur cycle in arid *** on the calculation,sulfide oxidation plays the primary role in the headwater and upstream in the Qilian-Mountains area,where sulfide is widely *** the proportion of evaporites dissolution contributing to riverine sulfate is much higher in downstream in a drier ***,less precipitation and higher temperature can lead to more intensive evaporation,affecting the process of sulfide oxidation and enhancing the rates of evaporites dissolution and sulfate precipitation in the basin.

关键词： Sulfur and oxygen isotopes Source apportionment Inverse model Arid environment Inland rivers Northwestern China

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Numerical Analysis of Heat Transfer Characteristics to Supercritical CO_(2) in a Vertical Mini-Channel:Transition and Pseudo-Boiling

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Journal of Thermal Science 2024年第1期33卷 101-113页

作者： YUAN Baoqiang WANG Wei XIN Gongming DU wenjing School of Energy and Power Engineering Shandong UniversityJi'nan 250061China

Large eddy simulations have been conducted to study upward transitional flows and heat transfer characteristics of supercritical CO_(2) in a vertical *** numerical simulation was carried out on a modified buoyantPimpleFOAM solver in OpenFOAM 7,and was verified using experiment *** results indicate that increasing the Grashof numbers can reduce the flow stability and make the flow transition *** are four stages of heat transfer in the transition process,i.e.,weakened,improved,recovered and normal heat *** heat transfer phenomena in the transition process were explained from three perspectives:thermal boundary layer theory,turbulent transport and pseudo-boiling *** transfer enhancement during transition is related to the transport of supercritical molecular clusters,and these molecular clusters are regarded as pseudo-bubbles in pseudo-boiling *** flow pattern of the pseudo-phases in the dia-Widom process contains single-phase flow,steady pseudo-film flow,unsteady pseudo-film flow,partial pseudo-bubbles flow and flocculent pseudo-film ***-bubbles have similar behaviors to subcritical bubbles,i.e.,break-up,deformation,condensation and *** researches in this work are favorable for understanding the heat transfer mechanism of supercritical fluids during flow transition.

关键词： supercritical heat transfer large eddy simulation transition pseudo-boiling

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Targeted drug approvals in 2023:breakthroughs by the FDA and NMPA

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Signal Transduction and Targeted Therapy 2024年第3期9卷 813-821页

作者： Lang Zheng wenjing Wang Qiu Sun Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China West China Medical Publishers West China HospitalSichuan UniversityChengdu 610041China

According to the official website of China’s National Medicines and Pharmaceutical Administration(NMPA),a total of 87 novel drugs were approved in China in 2023,with targeted drugs accounting for 67.8%of the total,amounting to 59 drugs(Fig.1a;Table 1)[https://***/yaopin/ypjgdt/***].Notably,domestic innovation is flourishing,with five first-in-class drugs,including Glumetinib,a c-Met inhibitor from Haihe Biopharma;Leritrelvir,a 3CL protease inhibitor from Raynovent;Anaprazole,a proton pump inhibitor from Xuanzhu Biopharm;Pegol-Sihematide,an EPO drug from Hansoh Pharma;and Zuberitamab from BioRay Biopharmaceutical Co.,***,the world’s first allosteric inhibitor targeting TYK2,Sotyktu(deucravacitinib),has been approved for the treatment of psoriasis and Selumetinib,a MEK inhibitor co-developed by AstraZeneca and Merck Sharp&Dohme(MSD),became the first approved drug in China for the treatment of neurofibromatosis type I(NF1).Beyond these drugs,the approval of novel drug types such as CAR-T cell products,siRNA,monoclonal antibodies,dual antibodies,and ADCs in China is a significant development in the country’s pharmaceutical industry(Fig.1a).

关键词： drugs Merck approval

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Covalent Triazine Framework Nanosheets:Synthesis and Energy Conversion and Storage

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Chinese Journal of Chemistry 2024年第3期42卷 301-316页

作者： Zhao Liu Congxu Wang wenjing Yuan Yuxi Xu School of Materials Science & Engineering Hebei University of TechnologyTianjin300130 China School of Engineering Westlake UniversityHangzhouZhejiang310024 China

Covalent triazine framework nanosheets (CTF NSs),an emerging class of two-dimensional nanomaterials,have received great attention due to their abundant active sites,permanent porosity,molecular structural diversity,superior chemical/thermal stability,and short charge diffusion path,enabling technological breakthroughs in a myriad of applications. The forefront developments and applications of CTF NSs as photocatalysts and electrochemical electrodes have conferred superior performance and made great impact in the field of energy and advanced catalysis. This forward-looking review aims to summarize the research trends,synthesis,properties of CTF NSs and their CTF counterpart,and highlight their progress in applications with respect to energy storage and conversion devices. Finally,the current challenges and future perspectives for CTF NSs are also presented.

关键词： Covalent triazine framework Nanosheets Photocatalysis Energy storage Charge transfer

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Impact of Media Information on Social Response in Disasters:A Case Study of the Freezing‑Rain and Snowstorm Disasters in Southern China in 2008

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International Journal of Disaster Risk Science 2024年第1期15卷 73-87页

作者： Jia He wenjing Duan Yuxuan Zhou Yun Su College of Geographic Science and Tourism Xinjiang Normal UniversityUrumqi 830054China Xinjiang Laboratory of Lake Environment and Resources in Arid Zone Urumqi 830054China Faculty of Geographical Science Beijing Normal UniversityBeijing 100875China Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing 100875China

Disaster information content is an objective mapping of disaster situations,social response,and public *** response to emergency is an important mechanism for implementing and guaranteeing emergency management of major natural hazard-related *** how disaster information content affects social response to emergencies is helpful for managing risk communication and efficient disaster *** on the 2008 freezing-rain and snowstorm disasters in southern China,this study used Python to extract 7,857 case-related media reports and applied natural language processing for text *** used three typical cases to identify and analyze disaster media report content and the relationship between these reports and the social response to the *** categories of disaster response-such as prewarning and forecasting,announcements by the authorities,and social mobilization-appeared in the disaster information in the media,along with disaster impact information,that is,real-time disaster *** response information and an appropriate amount of disaster impact information played important roles in prewarning,disaster relief,public opinion guidance,and social stability maintenance and can serve important functions in communicating with all stakeholders of emergency management,assisting or influencing emergency departments or individuals in decision making,and eliminating "information islands." Empathy caused the general public to become "disaster responders" through receiving *** and an excess of negative information may have a perverse amplification effect on public opinion and increase the unpredictability of the disaster situation and the risk of social crisis.

关键词： Emergency management Freezing-rain and snowstorm disasters Media reports on disasters Social response to emergencies China

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Effects of Heterologously Overexpressing PIP5K-Family Genes in Arabidopsis on Inflorescence Development

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Phyton-International Journal of Experimental Botany 2024年第1期93卷 97-117页

作者： Mingda yin Rui Luo Tana Liang Qi Wen Xiaotian Liang Yanpeng Wen Xuemei Hu Zhiyan Wang Chang Gao wenjing Ren Fenglan Huang College of Life Science and Food Engineering Inner Mongolia Minzu UniversityTongliao028000China Key Laboratory of Castor Breeding of the State Ethnic Affairs Commission Inner Mongolia Minzu UniversityTongliao028000China Inner Mongolia Industrial Engineering Research Center of Universities for Castor Inner Mongolia Minzu UniversityTongliao028043China Inner Mongolia Key Laboratory of Castor Breeding and Comprehensive Utilization Inner Mongolia Minzu UniversityTongliao028000China Inner Mongolia Engineering Research Center of Industrial Technology Innovation of Castor Inner Mongolia Minzu UniversityTongliao028000China

Castor is one of the top 10 oil crops in the world and has extremely valuable *** inflorescences directly affect yield,so the study of inflorescence development is very important in increasing castor *** previous studies have shown that the PIP5K gene family(PIP5Ks)is associated with inflorescence *** this study,to determine the function of each PIP5K gene in castor,a female Lm-type castor line,aLmAB2,was used to determine the relative expression levels of the PIP5Ks in castor *** PIP5K genes were heterologously overexpressed in Arabidopsis thaliana,the relative expression of each gene and the effect on plants was determined in ***,and the relationships among the PIP5Ks in castor were *** expression levels of the PIP5Ks in the female Lm-type castor line aLmAB2 were *** relative expression levels of the PIP5K9 and PIP5K11 genes were high(p<0.05)in isofemale inflorescences,and those of PIP5K1,PIP5K2,PIP5K6,and PIP5K8 were high(p<0.05)in female inflorescences but low(p<0.05)in bisexual *** PIP5Ks were heterologously overexpressed in ***,and T3-generation plants with stable genetic resistance,i.e.,AT-PIP5K^(+)plants(AT-PIP5K1^(+),AT-PIP5K2^(+),AT-PIP5K6^(+),AT-PIP5K8^(+),AT-PIP5K9^(+),and ATPIP5K11^(+) plants),were *** tests of the AT-PIP5K+plants showed that the growth of the main stem was significantly delayed in AT-PIP5K+plants compared with Columbia wild-type(WT)*** plants;the PIP5K1 and PIP5K2 genes promoted lateral stem growth and flower and silique development;and the PIP5K6,PIP5K8,PIP5K9 and PIP5K11 genes inhibited lateral stem growth and flower and silique *** correlations among PIP5Ks in castor suggest that there may be a synergistic relationship among PIP5K1,PIP5K2,and PIP5K6 in castor inflorescences,and PIP5K8,PIP5K9,and PIP5K11 are complementary to the other three genes.

关键词： Castor inflorescence development PIP5K gene family gene overexpression

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Cell reprogramming therapy for Parkinson’s disease

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Neural Regeneration Research 2024年第11期19卷 2444-2455页

作者： wenjing Dong Shuyi Liu Shangang Li Zhengbo Wang State Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunmingYunnan ProvinceChina Yunnan Key Laboratory of Primate Biomedical Research KunmingYunnan ProvinceChina

Parkinson’s disease is typically characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars *** studies have been performed based on the supplementation of lost dopaminergic neurons to treat Parkinson’s *** initial strategy for cell replacement therapy used human fetal ventral midbrain and human embryonic stem cells to treat Parkinson’s disease,which could substantially alleviate the symptoms of Parkinson’s disease in clinical ***,ethical issues and tumor formation were limitations of its clinical *** pluripotent stem cells can be acquired without sacrificing human embryos,which eliminates the huge ethical barriers of human stem cell *** widely considered neuronal regeneration strategy is to directly reprogram fibroblasts and astrocytes into neurons,without the need for intermediate proliferation states,thus avoiding issues of immune rejection and tumor *** induced pluripotent stem cells and direct reprogramming of lineage cells have shown promising results in the treatment of Parkinson’s ***,there are also ethical concerns and the risk of tumor formation that need to be *** review highlights the current application status of cell reprogramming in the treatment of Parkinson’s disease,focusing on the use of induced pluripotent stem cells in cell replacement therapy,including preclinical animal models and progress in clinical *** review also discusses the advancements in direct reprogramming of lineage cells in the treatment of Parkinson’s disease,as well as the controversy surrounding in vivo *** findings suggest that cell reprogramming may hold great promise as a potential strategy for treating Parkinson’s disease.

关键词： animal models astrocytes autologous cell reprogramming cell therapy direct lineage reprogramming dopaminergic neurons induced pluripotent stem cells non-human primates Parkinson’s disease

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Single image defogging via multi-exposure image fusion and detail enhancement

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Journal of Safety Science and Resilience 2024年第1期5卷 37-46页

作者： wenjing Mao Dezhi Zheng Minze Chen Juqiang Chen School of Information and Electronics Advanced Research Institute of Multidisciplinary ScienceBeijing Institute of TechnologyBeijing100081China Chinese Aeronautical Establishment Beijing100012China

Outdoor cameras play an important role in monitoring security and social *** a common weather phenomenon,haze can easily affect the quality of camera shooting,resulting in loss and distortion of image *** paper proposes an improved multi-exposure image fusion defogging technique based on the artificial multi-exposure image fusion(AMEF)***,the foggy image is adaptively exposed,and the fused image is subsequently obtained via multiple *** fusion weight is determined by the saturation,contrast,and ***,the image fused by a multi-scale Laplacian algorithm is enhanced with simple adaptive details to obtain a clearer defogging *** is subjectively and objectively verified that this algorithm can obtain more image details and distinct picture colors without a priori information,effectively improving the defogging ability.

关键词： Image defogging Multi-scale fusion Laplacian pyramid Adaptive detail enhancement

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Day-ahead Voltage-stability-constrained Network Topology Optimization with Uncertainties

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 730-741页

作者： Dingli Guo Lei Wang Ticao Jiao Ke Wu wenjing Yang the School of Electrical and Electronic Engineering Shandong University of TechnologyZibo 255000China

A day-ahead voltage-stability-constrained network topology optimization(DVNTO)problem is proposed to find the day-ahead topology schemes with the minimum number of operations(including line switching and bus-bar splitting)while ensuring the sufficient hourly voltage stability margin and the engineering operation requirement of power *** AC continuation power flow and the uncertainty from both renewable energy sources and loads are incorporated into the *** proposed DVNTO problem is a stochastic,largescale,nonlinear integer programming *** solve it tractably,a tailored three-stage solution methodology,including a scenario generation and reduction stage,a dynamic period partition stage,and a topology identification stage,is ***,to address the challenges posed by uncertainties,a novel problem-specified scenario reduction process is proposed to obtain the representative ***,to obtain the minimum number of necessary operations to alter the network topologies for the next 24-hour horizon,a dynamic period partition strategy is presented to partition the hours into several periods according to the hourly voltage information based on the voltage stability ***,a topology identification stage is performed to identify the final network topology *** effectiveness and robustness of the proposed three-stage solution methodology under different loading conditions and the effectiveness of the proposed partition strategy are evaluated on the IEEE 118-bus and 3120-bus power systems.

关键词： Network topology optimization static voltage stability line switching bus-bar splitting renewable energy source

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Embracing digital mindsets to ensure a sustainable future

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Frontiers of Environmental Science & Engineering 2024年第3期18卷 177-179页

作者： Chengjun Li Riqing Yu wenjing Ning Huan Zhong Christian Sonne Institute of Environmental Research at Greater Bay Area Guangzhou UniversityGuangzhou 510000China Department of Biology Center for EnvironmentBiodiversity and ConservationThe University of Texas at TylerTylerTX 75701USA School of Environment Nanjing UniversityNanjing 210000China Environmental and Life Science Program Trent UniversityPeterboroughOntarioK9H 0A1Canada Faculty of Science and Technology Aarhus UniversityRoskildeDenmark 4000The Kingdom of Denmark Sustainability Cluster School of EngineeringUniversity of Petroleum&Energy StudiesDehradunUttarakhand 248001India

The 19th Asian Games astounded global audiences with an opening spectacle that showcased stunning digital fireworks(International Olympic Committee,2021;Zhe,2023).The groundbreaking display was brought to life through virtual reality(VR)and augmented reality(AR)*** sets a pioneering example to replace conventional fireworks in major international events as well as in other large-scale entertainment activities,marking a historic milestone in the pursuit of a sustainable and healthy future.

关键词： Wildlife Climate Change Heavy metals Noise LAN Light pollution

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