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Characteristics of the microbial communities regulate soil multi-functionality under different cover crop amendments in Ultisol

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Journal of Integrative Agriculture 2024年第6期23卷 2099-2111页

作者： Guilong Li Xiaofen Chen wenjing qin Jingrui Chen Ke Leng Luyuan Sun Ming Liu Meng Wu Jianbo Fan Changxu Xu Jia Liu Soil and Fertilizer&Resources and Environment Institute Jiangxi Academy of Agricultural SciencesNanchang 330200China Key Laboratory of Acidified Soil Amelioration and Utilization Ministry of Agriculture and Rural AffairsNanchang 330200China Ecological Experimental Station of Red Soil Chinese Academy of SciencesYingtan 335211China

The use of cover crops is a promising strategy for influencing the soil microbial consortium,which is essential for the delivery of multiple soil functions(i.e.,soil multifunctionality).Nonetheless,relatively little is known about the role of the soil microbial consortium in mediating soil multifunctionality under different cover crop amendments in dryland ***,we assessed the multifunctionality of soils subjected to four cover crop amendments(control,non-amended treatment;RD,radish monoculture;HV,hairy vetch monoculture;and RDHV,radish-hairy vetch mixture),and we investigated the contributions of soil microbial richness,network complexity,and ecological clusters to soil *** results demonstrated that cover crops whose chemical composition differed from that of the main plant crop promoted higher multifunctionality,and the radish-hairy vetch mixture rendered the highest *** obtained evidence that changes in soil microbial richness and network complexity triggered by the cover crops were associated with higher soil ***,specialized microbes in a key ecological cluster(ecological cluster 2)of the soil microbial network were particularly important for maintaining soil *** results highlight the importance of cover crop-induced variations in functionally important taxa for promoting the soil multifunctionality of dryland Ultisols.

关键词： cover crops soil multifunctionality microbial richness network complexity ecological cluster

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Van der Waals heterostructure tunnel FET with potential modulation beyond junction region

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Science China(Information Sciences) 2022年第10期65卷 311-313页

作者： wenjing qin Yawei LV Zhen XIA Lei LIAO Changzhong JIANG Key Laboratory for Micro-/Nano-Optoelectronic Devices of the Ministry of Education School of Physics and Electronics Hunan University School of Physics and Electronics Hunan Normal University School of Physics and Technology Wuhan University

Dear editor,State-of-the-art semiconductor technology is approaching the atomic scale, greatly boosting the switching behavior of transistors towards the physical limit of the thermionic emission mechanism [1, 2]. A f... 详细信息

关键词： TRANSISTORS

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以β-淀粉样蛋白为靶点的抗阿尔茨海默病药物的研究现状

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现代医药卫生 2024年第12期40卷 2099-2103,2108页

作者：秦文静(综述) 古安城温格思(审校) 南昌大学第一附属医院科技处江西南昌330006 南方医科大学南方医院临床药学中心广东广州510515 广州医科大学附属第一医院临床研究管理部广东广州510120

β-淀粉样蛋白(Aβ)被认为是介导阿尔茨海默病(AD)发生发展的关键因素。Aβ的生成与清除的失衡将导致脑内Aβ大量堆积而引起聚集,进而对神经元细胞造成损伤,产生认知障碍,引起痴呆症状。为有效治疗AD,近年来,开展了大量以Aβ为靶点的临... 详细信息

β-淀粉样蛋白(Aβ)被认为是介导阿尔茨海默病(AD)发生发展的关键因素。Aβ的生成与清除的失衡将导致脑内Aβ大量堆积而引起聚集,进而对神经元细胞造成损伤,产生认知障碍,引起痴呆症状。为有效治疗AD,近年来,开展了大量以Aβ为靶点的临床研究,包括抑制Aβ的生成、聚集,促进Aβ清除等策略,但相关研究屡屡受挫。该文通过检索近些年国内外文献,针对Aβ在AD发展过程中的生物学效应及其临床研究现状进行探讨与梳理,以期为Aβ的靶向治疗策略提供思路。

关键词：阿尔茨海默病 β-淀粉样蛋白蛋白聚集神经损伤治疗策略综述

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In-situ formed hierarchical transition metal oxide nanoarrays with rich antisite defects and oxygen vacancies for high-rate energy storage devices

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Chinese Chemical Letters 2022年第5期33卷 2669-2676页

作者： Teng Wang Bo Xu You Wang Jiaqi Lei wenjing qin Ke Gui Chuying Ouyang Kai-Jie Chen Hongxia Wang Key Laboratory of Special Functional and Smart Polymer Materials of Ministry of Industry and Information Technology Xi’an Key Laboratory of Functional Organic Porous MaterialsDepartment of ChemistrySchool of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China School of Chemistry and Physics Faculty of ScienceQueensland University of TechnologyBrisbaneQLD 4001Australia Department of Physics Laboratory of Computational Materials PhysicsJiangxi Normal UniversityNanchang 330022China

Developing transition metal oxides(TMOs)with high energy,power,and long cycle lifetime for elec-tric energy storage devices remains a critical challenge to ***,we demonstrate a facile method that enables in-situ transformation of nickel cobalt oxide nanowire arrays(NiCoO NWA)into hierarchical nanowire-nanosheet arrays(ac-NiCoO NWSA)for enhanced energy storage *** specifically,the method leads to formation of atomically thin nanosheets(only 2.0 nm)and creates abundant an-tisite defects and oxygen *** to these merits,the as-prepared ac-NiCoO NWSA electrode exhibits over five-fold higher specific capacity,superior rate capability(up to 100 A/g),and excellent cy-cling stability of 10,000 cycles at 50 A/g in alkaline electrolyte compared to pristine NiCoO *** functional theory(DFT)simulations elucidate the electrochemical activity enhancement mechanism of the ***,our method triggers similar structural reconstruction phenomenon on other TMOs including ZnCo-,CoMn-and ZnNiCo-oxides,proving the universality of the *** findings provide a general method towards simultaneously manipulating the micro-morphologies and defects of TMOs for advanced energy storage devices.

关键词： Transition metal oxides In-situ transformation Oxygen vacancy Antisite defects High-rate Hybrid supercapacitors

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Stepping forward:T-cell redirecting bispecific antibodies in cancer therapy

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2361-2377页

作者： Xiaojing qin wenjing Ning Han Liu Xue Liu Wenxin Luo Ningshao Xia State Key Laboratory of Vaccines for Infectious Diseases Xiang An Biomedicine LaboratorySchool of Public HealthXiamen UniversityXiamen 361102China National Institute of Diagnostics and Vaccine Development in Infectious Diseases State Key Laboratory of Molecular Vaccinology and Molecular DiagnosticsNational Innovation Platform for IndustryeEducation Integration in Vaccine Researchthe Research Unit of Frontier Technology of Structural Vaccinology of Chinese Academy of Medical SciencesXiamen UniversityXiamen 361102China

T cell-redirecting bispecific antibodies are specifically designed to bind to tumor-associated antigens,thereby engaging with CD3 on the T cell *** linkage between tumor cells and T cells actively triggers T cell activation and initiates targeted killing of the identified tumor *** antibodies have emerged as one of the most promising avenues within tumor ***,despite success in treating hematological malignancies,significant advancements in solid tumors have yet to be *** this review,we aim to address the critical challenges associated with T cellredirecting bispecific antibodies and explore novel strategies to overcome these obstacles,with the ultimate goal of expanding the application of this therapy to include solid tumors.

关键词： Bispecific antibody(BsAbs) T-cell redirecting BsAbs Tumor-associated antigens Toxicity Cytokine release syndrome Tumor microenvironment Cancer immunotherapy Combination therapy strategies

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急性单侧外周前庭病变病因初步探究

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神经损伤与功能重建 2024年第2期19卷 81-85页

作者：朱艳含钱果秦文静方毅徐姣周涛常丽英湖北文理学院附属医院/襄阳市中心医院神经内科湖北襄阳441021 武汉科技大学医学部医学院武汉430081

目的:通过分析急性单侧外周前庭病变(acute unilateral peripheral vestibular dysfunction,AUPVD)患者的基本信息、前庭功能、影像学检查、治疗效果等指标,探究AUPVD的可能病因、累及部位。方法:收集2022年2月~4月我科收治的符合纳入... 详细信息

目的:通过分析急性单侧外周前庭病变(acute unilateral peripheral vestibular dysfunction,AUPVD)患者的基本信息、前庭功能、影像学检查、治疗效果等指标,探究AUPVD的可能病因、累及部位。方法:收集2022年2月~4月我科收治的符合纳入标准的AUPVD患者36例的临床资料,其中30例接受视频头脉冲(v HIT)检查,26例接受激素治疗,3例行迷路钆造影增强扫描。分析、比较患者的检查结果及脑血管病危险因素。结果:30例行v HIT检查的患者中,结果异常25例,其中12例(48%)水平半规管vHIT异常,但前管正常;部分迷路钆造影增强检查的患者可见病变侧前庭迷路强化信号,未观察到前庭神经的强化信号;26例使用激素治疗的患者中,17例(65.4%)效果较好,9例(34.6%)效果欠佳,后者平均年龄及至少合并1项脑血管病危险因素占比明显高于前者(P<0.05)。结论:AUPVD的病因可能包括炎性、缺血等多种机制;可能累及前庭神经、前庭迷路等多处部位。

关键词：急性单侧外周前庭病变双温检查视频头脉冲试验钆造影激素治疗

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Effect of strain on electrochemical performance of Janus MoSSe monolayer anode material for Li-ion batteries: First-principles study

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Chinese Physics B 2021年第4期30卷 394-401页

作者： Guoqing Wang wenjing qin Jing Shi Department of Physics Jiangxi Normal UniversityNanchang 330022China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

First-principles calculations are performed to investigate the effect of strain on the electrochemical performance of Janus MoSSe *** calculation focuses on the specific capacity,intercalation potential,electronic structure,and migration behavior of Li-ion under various strains by using the climbing-image nudged elastic band *** result shows that the specific capacity is nearly unchanged under *** interestingly,the tensile strain can cause the intercalation potential and Li-ion migration energy barrier increase in MoSSe monolayer,whereas the compressive strain can lead to the intercalation potential and energy barrier ***,the rate performance of the MoSSe anode is *** analyzing the potential energy surface of MoSSe surface and equilibrium adsorption distance of Li-ion,we explain the physical origin of the change in the intercalation potential and migration energy *** increase of MoSSe potential energy surface and the decrease of adsorption distance caused by tensile strain are the main reason that hinders Li-ion migration.

关键词： Janus Mo SSe monolayer strain effect specific capacity migration behavior

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Annealing Effect of ZnO on the Performance of Inverted Organic Photovoltaic Devices

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Journal of Materials Science & Technology 2014年第2期30卷 197-202页

作者： wenjing qin Guojing Ding Xinrui Xu Liying Yang Shougen Yin Key Laboratory of Display Materials & Photoelectric Devices(Ministry of Education) and School of Materials Science &Engineering Tianjin University of Technology Tianjin Key Lab for Photoelectric Materials & Devices

ZnO nanoparticles films were prepared via sol-gel process and incorporated into inverted organic photovoltaic devices with a structure of ITO/ZnO/P3HT：PCBM/MoO3/Ag, in which ZnO film served as an electron selective layer. The effects of annealing temperature of ZnO film on the device performance were investigated. When the annealing temperature was 300℃, a well-arranged ZnO thin film was obtained, and the optimized device had doubled short circuit current density （Jsc） and seven-fold higher power conversion efficiency （PCE） compared to the devices without ZnO film. This improvement could be attributed to the enlarged interfacial area of ZnO/active layer and better energy band matching which causes an efficient electron extraction and a decreased interface energy barrier. At particularly high annealing temperature, dramatically increased sheet resistance of indium tin oxide （ITO） was found to cause PCE deterioration. Our finding indicates that it is highly important to investigate both morphology and electrical effects for understanding and optimizing organic photovoltaic （OPV） performance.

关键词： ZnO Inverted organic photovoitaic Annealing effect

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Genomic selection of eight fruit traits in pear

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Horticultural Plant Journal 2024年第2期10卷 318-326页

作者： Manyi Sun Mingyue Zhang Satish Kumar Mengfan qin Yueyuan Liu Runze Wang Kaijie Qi Shaoling Zhang wenjing Chang Jiaming Li Jun Wu College of Horticulture State Key Laboratory of Crop Genetics&Germplasm Enhancement and UtilizationNanjing Agricultural UniversityNanjingJiangsu 210095China State Key Laboratory of Crop Biology College of Horticulture Science and EngineeringShandong Agricultural UniversityTai'anShandong 271018China The New Zealand Institute for Plant and Food Research Limited Private Bag 1401Havelock North 4157New Zealand Zhongshan Biological Breeding Laboratory NanjingJiangsu 210014China

Genomic selection (GS) has the potential to improve selection efficiency and shorten the breeding cycle in fruit tree breeding. In this study,we evaluated the effect of prediction methods, marker density and the training population (TP) size on pear GS for improving its performance and reducing cost. We evaluated GS under two scenarios:(1) five-fold cross-validation in an interspecific pear family;(2) independent validation. Based on the cross-validation scheme, the prediction accuracy (PA) of eight fruit traits varied between 0.33 (fruit core vertical diameter)and 0.65 (stone cell content). Except for single fruit weight, a slightly better prediction accuracy (PA) was observed for the five parametrical methods compared with the two non-parametrical methods. In our TP of 310 individuals, 2 000 single nucleotide polymorphism (SNP) markers were sufficient to make reasonably accurate predictions. PAs for different traits increased by 18.21%-46.98%when the TP size increased from 50to 100, but the increment was smaller (-4.13%-33.91%) when the TP size increased from 200 to 250. For independent validation, the PAs ranged from 0.11 to 0.45 using rrBLUP method. In summary, our results showed that the TP size and SNP numbers had a greater impact on the PA than prediction methods. Furthermore, relatedness among the training and validation sets, and the complexity of traits should be considered when designing a TP to predict the test panel.

关键词： Pear Pyrus Prediction method TP size SNP marker number

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Night warming increases wheat yield by improving pre-anthesis plant growth and post-anthesis grain starch biosynthesis

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Journal of Integrative Agriculture 2024年第2期23卷 536-550页

作者： Yonghui Fan Boya qin Jinhao Yang Liangliang Ma Guoji Cui Wei He Yu Tang wenjing Zhang Shangyu Ma Chuanxi Ma Zhenglai Huang College of Agronomy Anhui Agricultural University/Key Laboratory of Wheat Biology and Genetic Improvement in South Yellow&Huai River ValleyMinistry of Agriculture and Rural AffairsHefei 230036China Xianyang Central Station for Agricultural Technology Extension Xianyang 712000China

Global climate change is characterized by asymmetric warming,i.e.,greater temperature increases in winter,spring,and nighttime than in summer,autumn,and *** experiments were conducted using four wheat cultivars,namely‘Yangmai 18’(YM18),‘Sumai 188’(SM188),‘Yannong 19’(YN19),and‘Annong 0711’(AN0711),in the two growing seasons of 2019-2020 and 2020-2021,with passive night warming during different periods in the early growth *** treatments were night warming during the tillering-jointing(NW_(T-J)),jointing-booting(NWJ-B),and booting-anthesis(NWB-A)stages,with ambient temperature(NN)as the *** effects of night warming during different stages on wheat yield formation were investigated by determining the characteristics of dry matter accumulation and translocation,as well as sucrose and starch accumulation in wheat *** wheat yields of all four cultivars were significantly higher in NW_(T-J)than in NN in the 2-year *** yield increases of semi-winter cultivars YN19 and AN0711 were greater than those of spring cultivars YM18 and *** NW_(T-J)increased wheat yield mainly by increasing the 1,000-grain weight and the number of fertile spikelets,and it increased dry matter accumulation in various organs of wheat at the anthesis and maturity stages by increasing the growth rate at the vegetative growth *** flag leaf and spike showed the largest increases in dry matter ***_(T-J)also increased the grain sucrose and starch contents in the early and middle grain-filling stages,promoting yield ***,night warming between the tillering and jointing stages increased the pre-anthesis growth rate,and thus,wheat dry matter production,which contributed to an increase in wheat yield.

关键词： wheat asymmetric warming dry matter accumulation and translocation starch yield

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