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Dihydromyricetin‑Incorporated Multilayer Nanofibers Accelerate Chronic Wound Healing by Remodeling the Harsh Wound Microenvironment

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Advanced Fiber Materials 2022年第6期4卷 1556-1571页

作者： Zijian Wang wenjie you Wang Wang Weiqun Tian Fangjin Chen Yu Xiao Yun Chen Xinghuan Wang Department of Urology Zhongnan Hospital of Wuhan University430071 WuhanChina Department of Biomedical Engineering and Hubei Province Key Laboratory of Allergy and Immune Related Disease School of Basic Medicine SciencesTaiKang Medical SchoolWuhan University430071 WuhanChina Center for Quantitative Biology School of Life SciencesPeking University100871 BeijingChina

The harsh microenvironment in wound(HMW)remains a major obstacle to chronic wound *** a series of bioactive materials have been developed,few of them are multi-functional and able to accelerate wound healing via precisely remodeling the ***,a series of dihydromyricetin(DHM)-incorporated multilayer nanofibers(termed DQHP-n,n=0,2,6 and 10)are fabricated using a layer-by-layer(LBL)self-assembly *** average diameters of DQHP-n significantly increase from 0.30±0.16μm to 0.84±0.28μm(P<0.05)along with the n value increased from 0 to 10,the tensile strength of that is also significantly improved from 1.12±0.15 MPa to 2.16±0.30 MPa(P<0.05),and the water contact angle of that significantly decreases from 129.1±1.5°to 76.6±3.9°(P<0.05).The DQHP-n are found to be biocompatible,in which DQHP-6 promoted cell migration through activation of the epithelial–mesenchymal transformation(EMT)pathway and reconstruction of the HMW by stopping bleeding,killing bacteria,eliminating inflammation,and scavenging reactive oxygen species(ROS).The in vivo evaluation is carried out via an ***-infected rat skin regeneration *** DQHP-6 group demonstrates the best effect,as it healed up to 98.5±1.0%of the wound area at day ***-6 differentially regulates the mRNA expressions of several cytokines(FGF2,PDGF,IL-1α,IL-6,IL10,and TGF-β),which ends to reductions of total inflammatory cells(CD45^(+) cells)and M1 macrophages(CD80^(+) and CD86^(+) cells),proliferation of host cell(Ki67^(+) cells),and enhancement of collagen *** conclusion,DQHP-6 exhibits multifunctional properties for HMW,and can serve as a promising wound dressing for clinical transformation.

关键词： Dihydromyricetin Quaternized chitosan Hyaluronic acid Nanofiber Wound dressing

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响应式网页设计与HTML/CSS实践研究

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移动信息 2024年第1期46卷 236-239页

作者：尤文杰李瑞芬郑州理工职业学院郑州450000

文中探讨了基于HTML/CSS的响应式网页设计框架,该框架将网页设计分为内容层、布局层和样式层,并强调了模块化设计和媒体查询的重要性。文中首先介绍了响应式网页设计的核心概念与原则,强调了流体布局、媒体查询等关键技术在实现响应式... 详细信息

文中探讨了基于HTML/CSS的响应式网页设计框架,该框架将网页设计分为内容层、布局层和样式层,并强调了模块化设计和媒体查询的重要性。文中首先介绍了响应式网页设计的核心概念与原则,强调了流体布局、媒体查询等关键技术在实现响应式设计中的作用。随后,提出了一个分层结构的实现框架,将网页分为内容层、布局层和样式层,使得网页设计更具可管理性与灵活性。在模块化设计方面,将页面拆解为独立的模块,提高了代码的重用性与可维护性。最后,通过媒体查询技术,实现了根据设备特性应用不同CSS规则,在不同屏幕尺寸下提供最佳用户体验的目的。

关键词：响应式网页 CSS 设计框架开发流程

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A Cyclic Constitutive Model Based on Crystal Plasticity for Body-Centered Cubic Cyclic Softening Metals

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Acta Mechanica Solida Sinica 2024年第1期37卷 33-42页

作者： Xuehong Ren wenjie Zhao Shaopu Yang Guilin Wen State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China School of Mechanical Engineering Tianjin Sino-German University of Applied SciencesTianjin 300350China State Key Laboratory of Mechanical Behavior in Traffic Engineering Structure and System Safety Shijiazhuang Tiedao UniversityShijiazhuang 050043China

Under the framework of the small deformation crystal plasticity theory,a crystal plastic cyclic constitutive model for body-centered cubic(BCC)cyclic softening polycrystalline metals is *** constitutive model introduces the isotropic softening rule that includes two different mechanisms:namely softening under monotonic deformation and softening under cyclic deformation on each slip ***,a modified Armstrong-Frederick nonlinear kinematic hardening rule is *** appropriate explicit scale transition rule is selected to extend the single crystal constitutive model to the polycrystalline constitutive *** the model is used to predict the uniaxial and multiaxial ratcheting deformation of BCC axle steel EA4T to verify the rationality of the proposed *** simulation results indicate that the newly established crystal plasticity model can not only describe the cyclic softening characteristics of BCC axle steel EA4T well,but also reasonably describe the evolution laws of uniaxial ratcheting and nonproportional multiaxial ratcheting ***,the established crystal plastic cyclic constitutive model can reasonably predict the ratcheting behavior of BCC single crystal as well.

关键词： Crystal plasticity Constitutive model Softening Ratcheting

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Composite Recommendation of Artworks in E-Commerce Based on User Keyword-Driven Correlation Graph Search

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Tsinghua Science and Technology 2024年第1期29卷 174-184页

作者： Jingyun Zhang wenjie Zhu Byoung Jin Ahn Yongsheng Zhou School of Design Dongseo UniversityBusan 47011Republic of Korea Institute of Art and Design Jiangsu University of TechnologyChangzhou 213001China Jinling Wenyun Art Design Co. Ltd.Zhenjiang 212000China Institute of Art and Design Krirk UniversityBangkok 10220Thailand Shandong Provincial University Laboratory for Protected Horticulture Weifang University of Science and TechnologyShouguang 262700China

With the ever-increasing diversification of people’s interests and preferences,artwork has become one of the most popular commodities or investment goods in E-commerce,and it increasingly attracts the attention of the ***,many real-world or virtual artworks can be found in E-commerce,and finding a means to recommend them to appropriate users has become a significant task to alleviate the heavy burden on artwork selection decisions by *** research mainly studies the problem of single-artwork recommendation while neglecting the more practical but more complex composite recommendation of artworks in E-commerce,which considerably influences the quality of experience of potential users,especially when they need to select a set of artworks instead of a single *** by this limitation,we put forward a novel composite recommendation approach to artworks by a user keyword-driven correlation graph search named ART_(com-rec).Through ART_(com-rec),the recommender system can output a set of artworks(e.g.,an artwork composite solution)in E-commerce by considering the keywords typed by a user to indicate his or her personalized ***,we validate the feasibility of the ART_(com-rec) approach by a set of simulated experiments on a real-world PW dataset.

关键词： composite recommendation artwork user keywords E-commerce correlation graph search

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Robust Regularization Design of Graph Neural Networks Against Adversarial Attacks Based on Lyapunov Theory

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Chinese Journal of Electronics 2024年第3期33卷 732-741页

作者： wenjie YAN Ziqi LI Yongjun QI School of Artificial Intelligence Hebei University of Technology School of Computer Science and Engineering of North China Institute of Aerospace Engineering

The robustness of graph neural networks（GNNs） is a critical research topic in deep *** researchers have designed regularization methods to enhance the robustness of neural networks,but there is a lack of theoretical analysis on the principle of *** order to tackle the weakness of current robustness designing methods,this paper gives new insights into how to guarantee the robustness of GNNs.A novel regularization strategy named Lya-Reg is designed to guarantee the robustness of GNNs by Lyapunov *** results give new insights into how regularization can mitigate the various adversarial effects on different graph *** experiments on various public datasets demonstrate that the proposed regularization method is more robust than the state-of-theart methods such as L1-norm,L2-norm,L2-norm,Pro-GNN,PA-GNN and GARNET against various types of graph adversarial attacks.

关键词： Training Deep learning Garnets Robustness Graph neural networks

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Design of integral sliding mode guidance law based on disturbance observer

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Journal of Systems Engineering and Electronics 2024年第1期35卷 186-194页

作者： ZHOU Jianping ZHANG wenjie ZHOU Hang LI Qiang XIA Qunli School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China School of Informatic Engineering Mianyang Techers’CollegeMianyang 62100China Beijing Institute of Electronic System Engineering Beijing 100854China Beijing Institute of Space Long March Vehicle Beijing 100076China

With the increasing precision of guidance,the impact of autopilot dynamic characteristics and target maneuvering abilities on precision guidance is becoming more and more *** order to reduce or even eliminate the autopilot dynamic operation and the target maneuvering influence,this paper suggests a guidance system model involving a novel integral sliding mode guidance law(ISMGL).The method utilizes the dynamic characteristics and the impact angle,combined with a sliding mode surface scheme that includes the desired line-ofsight angle,line-of-sight angular rate,and second-order differential of the angular *** the same time,the evaluation scenario considere the target maneuvering in the system as the external disturbance,and the non-homogeneous disturbance observer estimate the target maneuvering as a compensation of the guidance *** proposed system’s stability is proven based on the Lyapunov stability *** simulations reveale that ISMGL effectively intercepted large maneuvering targets and present a smaller miss-distance compared with traditional linear sliding mode guidance laws and trajectory shaping guidance ***,ISMGL has a more accurate impact angle and fast convergence speed.

关键词： disturbance observer pilot dynamics integral sliding mode impact angle constraint maneuvering target

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High Power Density EV Integrated Fast Battery Chargers Based on the General Torque Cancelation Law for Three-Phase Motors

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 756-766页

作者： Yanxiong Lei Guiping Du Tuhuan Li wenjie Ma Xueyi Wang School of Electric Power South China University of TechnologyGuangzhou 510641China

Integrated battery chargers are highly effective for saving costs and improving the power density of on-board chargers in electric vehicles (EVs), However, achieving torque elimination of the commonly used three-phase (3p) motors during the fast-charging process is challenging. In this paper, the general torque cancelation law applied in 3p permanent magnet synchronous motors (PMSMs) and induction motors (IMs) is derived to design high power density integrated fast battery chargers. Two novel integrated systems with fast-charging and vehicle-to-grid (V2G) capabilities are proposed based on this law. The main advantages of the proposed systems are: (1) Two filter inductors are constituted by the stator windings while charging, and only one external inductor and several contactors are supplemented to the motor-drive circuit. Therefore, the proposed integrated systems possess high power density;(2) The 3p open-winding (OW) motor is employed, with no need to modify the propulsion system or redesign the interior structure of the motor;(3) Employing an individual controller for each phase of the inner current loop control, the proposed systems realize unity power factors and low current harmonics in the fast-charging and V2G mode. Simulation and experimental results verify the feasibility of the proposed topologies and control strategies.

关键词： Electric vehicles(EVs) fast charging integrated battery charger 3p PMSM/IM torque cancelation

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Multi-UAVs Collaborative Path Planning in the Cramped Environment

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 529-538页

作者： Siyuan Feng Linzhi Zeng Jining Liu Yi Yang wenjie Song School of Automation Beijing Institute of TechnologyNanjing 210039China Nanjing Research Institute of Electronics Technology Nanjing 210039China Yichang Testing Technique Research Institute Yichang 443003China IEEE

Due to its flexibility and complementarity, the multiUAVs system is well adapted to complex and cramped workspaces, with great application potential in the search and rescue(SAR) and indoor goods delivery fields. However, safe and effective path planning of multiple unmanned aerial vehicles(UAVs)in the cramped environment is always challenging: conflicts with each other are frequent because of high-density flight paths, collision probability increases because of space constraints, and the search space increases significantly, including time scale, 3D scale and model scale. Thus, this paper proposes a hierarchical collaborative planning framework with a conflict avoidance module at the high level and a path generation module at the low level. The enhanced conflict-base search(ECBS) in our framework is improved to handle the conflicts in the global path planning and avoid the occurrence of local deadlock. And both the collision and kinematic models of UAVs are considered to improve path smoothness and flight safety. Moreover, we specifically designed and published the cramped environment test set containing various unique obstacles to evaluating our framework performance thoroughly. Experiments are carried out relying on Rviz, with multiple flight missions: random, opposite, and staggered, which showed that the proposed method can generate smooth cooperative paths without conflict for at least 60 UAVs in a few *** benchmark and source code are released in https://***/inin-xingtian/multi-UAVs-path-planner.

关键词： Collision avoidance conflict resolution multi-unmanned aerial vehicles(UAVs)system path planning

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Interplay between geometric and electronic structures of Pt entities over TiO_(2) for CO oxidation

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Science China Chemistry 2024年第2期67卷 705-714页

作者： Xixiong Zhang Wen Shi Shaobo Han Yong Li wenjie Shen School of Chemistry Dalian University of TechnologyDalian116024China State Key Laboratory of Catalysis Dalian Institution of Chemical PhysicsChinese Academy of SciencesDalian116023China

Monodispersed Pt colloids with a mean size of 2 nm were deposited uniformly on the {110} facets of a rod-shaped rutile TiO_(2),forming a well-defined Pt/TiO_(2) *** treatment of this precursor at elevated temperatures re-dispersed the Pt particles into clusters and ***-calcination at 673 K partially oxidized the Pt particle surface,while calcination at 773 K yielded Pt Oxclusters of 1.6 nm in 7–8 atomic *** calcination at 873 K formed a mixture of raft-like PtO_(x) clusters(1.6 nm,1–2 atomic layers) and cationic *** tested for CO oxidation at 373 K,the Pt particles showed a higher activity than the Pt Oxclusters,whereas the cationic single-atoms were much less *** H_(2)-reduction at 473 K converted the partially oxidized Pt particles into the metallic species,but they were encapsulated by TiO_(2)–xoverlayers because of the strong metal–support interactions,which decreased the activity dramatically.H_(2)-reduction of the PtO_(x) clusters at473 K enhanced the fraction of metallic Pt species without changing the size and geometry,and promoted the activity substantially.H_(2)-treatment of Pt single-atoms at 473 K increased the activity only moderately because most Pt species still kept at cationic *** results straightforwardly differentiated the catalytic behavior of Pt particles,clusters and single-atoms at the same metal loading and over the same TiO_(2) support,and further demonstrated that the electronic structures of Pt entities played a decisive role in the catalytic oxidation,in addition to the specified sizes.

关键词： Pt/TiO_(2)catalyst size effect Pt clusters active sites electronic structures CO oxidation

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Pattern dynamics and bifurcation in delayed SIR network with diffusion network

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International Journal of Biomathematics 2024年第2期17卷 87-111页

作者： wenjie Yang Qianqian Zheng Jianwei Shen School of Science Xuchang University XuchangHenan 461000P.R.China School of Mathematics and Statistics North China University of Water Resources and Electric Power Zhengzhou Henan 450046P.R.China

The spread of infectious diseases often presents the emergent properties,which leads to more dificulties in prevention and *** this paper,the SIR model with both delay and network is investigated to show the emergent properties of the infectious diseases'*** stability of the SIR model with a delay and two delay is analyzed to illustrate the effect of delay on the periodic outbreak of the *** the stability conditions of Hopf bifurcation are derived by using central manifold to obtain the direction of bifurcation,which is vital for the generation of emergent ***,numerical simulation shows that the connection probability can affect the types of the spatio-temporal patterns,further induces the emergent ***,the emergent properties of COVID-19 are explained by the above results.

关键词： Pattern dynamics SIR model random network connection probability Hopf bifurcation

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