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Thin polymer electrolyte with MXene functional layer for uniform Li^(+) deposition in all-solid-state lithium battery

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Green Energy & Environment 2024年第1期9卷 71-80页

作者： Weijie Kou Yafang Zhang wenjia Wu Zibiao guo Quanxian Hua Jingtao Wang School of Chemical Engineering Zhengzhou UniversityZhengzhou450001China

Solid polymer electrolyte(SPE) shows great potential for all-solid-state batteries because of the inherent safety and flexibility;however, the unfavourable Li+deposition and large thickness hamper its development and application. Herein, a laminar MXene functional layer-thin SPE layer-cathode integration(MXene-PEO-LFP) is designed and fabricated. The MXene functional layer formed by stacking rigid MXene nanosheets imparts higher compressive strength relative to PEO electrolyte layer. And the abundant negatively-charged groups on MXene functional layer effectively repel anions and attract cations to adjust the charge distribution behavior at electrolyte–anode interface. Furthermore,the functional layer with rich lithiophilic groups and outstanding electronic conductivity results in low Li nucleation overpotential and nucleation energy barrier. In consequence, the cell assembled with MXene-PEO-LFP, where the PEO electrolyte layer is only 12 μm, much thinner than most solid electrolytes, exhibits uniform, dendrite-free Li+deposition and excellent cycling stability. High capacity(142.8 mAh g-1), stable operation of 140 cycles(capacity decay per cycle, 0.065%), and low polarization potential(0.5 C) are obtained in this Li|MXene-PEO-LFP cell,which is superior to most PEO-based electrolytes under identical condition. This integrated design may provide a strategy for the large-scale application of thin polymer electrolytes in all-solid-state battery.

关键词： MXene nanosheet Laminar functional layer Thin polymer electrolyte Dendrite-free Liþdeposition All-solid-state lithium battery

Study of the multi-physics field-coupled model of the two-stage electrostatic precipitator

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Building Simulation 2024年第3期17卷 387-398页

作者： wenjia Hao Yu guo Yukun Wang Tao Yu Hao Gao Zhengwei Long Tianjin Key Laboratory of Indoor Air Environmental Quality Control School of Environmental Science and EngineeringTianjin UniversityWeijin Road 92Tianjin300072China Wuhan Second Ship Design and Research Institute WuhanChin

The two-stage electrostatic precipitator is widely used to purify oil mist ***,there is limited research on the influences of relative humidity,particle deposition characteristics,and the generation of gaseous ***,this paper established a numerical model of the electrostatic oil mist purifier and applied it to a two-stage electrostatic *** the model was used to investigate the corona discharge characteristics under different relative humidity conditions in the charged zone,the particle deposition characteristics,the purification efficiency,the ozone concentration distribution,and the oil vapor concentration distribution in the collection *** results indicate that,with a constant temperature,the corona current decreases as relative humidity increase,and there is a quadratic relationship between relative humidity and *** variation in relative humidity has little impact on the purification *** maximum ozone concentration occurs near the electrode line,and its concentration is influenced by the discharge current and inlet airflow *** oil vapor concentration reaches its maximum value at the side plates,with a value of 19 ppb,while it reaches the minimum value at the collecting zone electrode plate,with a value of 2 *** temperature is the main factor affecting the volatilization of the oil film,with higher temperatures resulting in higher oil vapor.

关键词： two-stage ESPs particle deposition corona discharge oil vapor

奥马珠单抗注射剂治疗哮喘致迟发型皮肤过敏反应1例分析

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中国药物警戒 2024年第2期21卷 211-212,222页

作者：李娜郭军郭文佳吕茵茵李彩宏牟向东清华大学附属北京清华长庚医院呼吸与危重症医学科清华大学临床医学院北京102218

目的提示临床奥马珠单抗注射剂联合治疗中重度过敏性哮喘使用过程中需加以关注可能引起的迟发型皮肤过敏反应。方法分析1例奥马珠单抗注射剂联合治疗中重度过敏性哮喘过程中,发生迟发型过敏大面积皮疹,通过不良反应相关性分析鉴别该... 详细信息

目的提示临床奥马珠单抗注射剂联合治疗中重度过敏性哮喘使用过程中需加以关注可能引起的迟发型皮肤过敏反应。方法分析1例奥马珠单抗注射剂联合治疗中重度过敏性哮喘过程中,发生迟发型过敏大面积皮疹,通过不良反应相关性分析鉴别该患者发生不良反应的可能药物和处理措施。结果患者不良反应为迟发型大面积过敏皮疹,排除患者病情和合并用药情况,判断引起患者严重大面积皮疹的原因为注射使用奥马珠单抗。不良反应相关性评价为“肯定”,立即予以停药并对症处理后患者好转,未发生后遗症。结论临床应加强监测奥马珠单抗注射剂引起的迟发型不良反应并及时采取措施,以免造成严重后果。

关键词：奥马珠单抗注射剂迟发型过敏反应过敏性哮喘皮肤过敏反应皮疹

A systematic review of the inequality of health burdens related to climate change

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Frontiers of Environmental Science & Engineering 2024年第5期18卷 137-153页

作者： Xinke Song Shihui Zhang Hai Huang Qun Ding Fang guo Yaxin Zhang Jin Li Mingyu Li wenjia Cai Can Wang State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing100084China Department of Earth System Science Tsinghua UniversityBeijing100084China

Climate change significantly impacts human health,exacerbating existing health inequalities and creating new *** study addresses the lack of systematic review in this area by analyzing 2440 publications,focusing on four key terms:health,disparities,environmental factors,and climate *** inclusion criteria limited the selection to English-language,peer-reviewed articles related to climate health hazards,ensuring the relevance and rigor of the synthesized *** process synthesized 65 relevant *** investigation revealed that recent research,predominantly from developed countries,has broadened its scope beyond temperature-related impacts to encompass diverse climate hazards,including droughts,extreme weather,floods,mental health issues,and the intersecting effects of Coronavirus Disease *** has highlighted exposure as the most studied element in the causal chain of climate change-related health inequalities,followed by adaptive capability and inherent *** most significant vulnerabilities were observed among populations with low socioeconomic status,ethnic minorities,and *** study further reveals research biases and methodological limitations,such as the paucity of attention to underdeveloped regions,a narrow focus on non-temperature-related hazards,challenges in attributing climate change effects,and a deficit of large-scale empirical *** findings call for more innovative research approaches and a holistic integration of physical,socio-political,and economic dimensions to enrich climate-health discourse and inform equitable policy-making.

关键词： Climate change Health impact Human well-being Inequality Vulnerability

Sustained release donepezil loaded PLGA microspheres for injection:Preparation,in vitro and in vivo study

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Asian Journal of Pharmaceutical Sciences 2015年第5期10卷 405-414页

作者： wenjia guo Peng Quan Liang Fang Dongmei Cun Mingshi Yang Department of Pharmaceutics Shenyang Pharmaceutical University110016China Department of Pharmacy Faculty of Health and Medical SciencesUniversity of CopenhagenUniversitetsparken 22100 CopenhagenØDenmark

The purpose of this study was to develop a PLGA microspheres-based donepezil(DP)formulation which was expected to sustain release of DP for one week with high encapsulation efficiency(EE).DP derived from donepezil hydrochloride was encapsulated in PLGA microspheres by the O/W emulsion-solvent evaporation *** optimized formulation which avoided the crushing of microspheres during the preparation process was characterized in terms of particle size,morphology,drug loading and EE,physical state of DP in the matrix and in vitro and in vivo release *** microspheres were prepared successfully with average diameter of 30m,drug loading of 15.92±0.31%and EE up to 78.79±2.56%.Scanning electron microscope image showed it has integrated spherical shape with no drug crystal and porous on its *** scanning calorimetry and X-ray diffraction results suggested DP was in amorphous state or molecularly dispersed in *** Tg of PLGA was increased with the addition of *** release profile in vitro was characterized with slow but continuous release that lasted for about one week and fitted well with first-order model,which suggested the diffusion governing release *** single-dose administration of DP microspheres via subcutaneous injection in rats,the plasma concentration of DP reached peak concentration at 0.50 d,and then declined gradually,but was still detectable at 15 d.A good correlation between in vitro and in vivo data was *** results suggest the potential use of DP microspheres for treatment of Alzheimer’s disease over long periods.

关键词： Donepezil PLGA Sustained release Microspheres In vitro and in vivo correlation

Performance Analysis of an Efficient Integration System of Coal-Fired Power Plant,Solar Thermal Energy and CO_(2)Capture

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Journal of Thermal Science 2024年第4期33卷 1509-1522页

作者： WANG Yuhao WANG Ruilin LIU Lanhua XING Chenjian guo Yafei YANG Qingshan YING Jiaheng SUN Jian LI wenjia LIU Yuanyuan ZHAO Chuanwen School of Energy and Mechanical Engineering Nanjing Normal UniversityNanjing210023China China Huadian Group Co.LTD.Shanghai Branch Shanghai200120China Key Laboratory of Efficient Utilization of Low and Medium Grade Energy(Tianjin University) Ministry of Education of ChinaTianjin300350China Huadian Zhengzhou Mechanical Design Institute Company Limited Zhengzhou450046China

Coal-fired power plant is a major contributor to greenhouse gas *** post-combustion capture is a promising method for CO_(2)emission reduction but the high thermal demand is *** address this issue,solar thermal energy and CO_(2)capture are jointly integrated into the coal-fired power plant in this *** solar thermal energy is employed to meet the heat requirement of the CO_(2)capture process,thereby avoiding the electricity loss caused by self-driven CO_(2)***,the heat released from the carbonation reaction of MgO adsorbent is integrated into the steam Rankine *** partially substituting the extracted steam for feedwater heating,the electricity output of the power plant is further *** to the results from the developed model,the system could achieve a CO_(2)capture rate of 86.5%and an electricity output enhancement of 9.8%compared to the reference system,which consists of a self-driven CO_(2)capture coal-fired power plant and PV generation *** operational strategy is also optimized and the amount of CO_(2)emission reduction on a typical day is increased by 11.06%.This work shows a way to combine fossil fuels and renewable energy for low carbon emissions and efficient power generation.

关键词： CO_(2)capture parabolic trough collector solar aided coal-fired electricity generation

Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma

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Signal Transduction and Targeted Therapy 2022年第3期7卷 896-908页

作者： Yiyi Xi Yuan Lin wenjia guo Xinyu Wang Hengqiang Zhao Chuanwang Miao Weiling Liu Yachen Liu Tianyuan Liu Yingying Luo Wenyi Fan Ai Lin Yamei Chen Yanxia Sun Yulin Ma Xiangjie Niu Ce Zhong Wen Tan Meng Zhou Jianzhong Su Chen Wu Dongxin Lin Department of Etiology and Carcinogenesis National Cancer Center/National Clinical Research Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Beijing Advanced Innovation Center for Genomics Biomedical Pioneering Innovation CenterPeking UniversityBeijing 100871China Cancer Institute Affiliated Cancer Hospital of Xinjiang Medical UniversityUrumqi 830000China School of Biomedical Engineering School of Ophthalmology and Optometry and Eye HospitalWenzhou Medical UniversityWenzhou 325011China Wenzhou Institute University of Chinese Academy of SciencesWenzhou 325000China Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine Nanjing Medical UniversityNanjing 211166China CAMS Key Laboratory of Genetics and Genomic Biology Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaGuangzhou 510060China

This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma(ESCC),which if diagnosed at advanced stages has<30%five-year survival *** genome-wide methylation sites of 91 ESCC and matched adjacent normal tissues,we identified 35,577 differentially methylated CpG sites(DMCs)and characterized their distribution patterns.

关键词： esophageal squamous diagnosis

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移动载体上天线工作角域分析

中国空间科学技术 2007年第3期27卷 29-32页

作者：郭文嘉中国空间技术研究院卫星应用系统部北京100053

静止轨道卫星与地球上移动载体间的数据通信时,要求移动载体在运动中始终保持通信链路信号不中断。从移动载体看卫星的仰角和方位角随移动载体在地球上的位置及其自身的姿态(方位,俯仰,滚动)而变,因此要求载体上天线既具有极宽的辐射方... 详细信息

静止轨道卫星与地球上移动载体间的数据通信时,要求移动载体在运动中始终保持通信链路信号不中断。从移动载体看卫星的仰角和方位角随移动载体在地球上的位置及其自身的姿态(方位,俯仰,滚动)而变,因此要求载体上天线既具有极宽的辐射方向图特性和良好的圆极化特性。按静止轨道卫星定点位置、载体工作地域、载体运动中姿态角(方位角、俯仰角、滚动角)变化范围,导出移动载体上天线实际需要的工作角域,为载体上天线辐射特性的设计给出了依据。

关键词：地球静止轨道卫星数据通信天线移动载体

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一种新式宽带宽方向图圆极化双环天线

中国空间科学技术 2006年第3期26卷 44-46,58页

作者：董涛郭文嘉中国空间技术研究院卫星应用系统部北京100080

提出了一种结构新颖的双环天线,该天线具有结构简单、宽带、宽波束、圆极化等诸多优点,通过实验测试方法验证了设计的有效性。同时提出了通过附加反射板的方法提高了该天线的低仰角增益,并对天线的输入阻抗和圆极化轴比有一定的改善作用。

关键词：双环天线圆极化宽频带飞行器