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MicroRNA-206 functions as a potential oligonucleotide therapeutics in preterm birth

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Chinese Medical Journal 2024年第8期137卷 1000-1002页

作者： wenfeng Deng Lina Chen Bolun Wen Xiaodi Wang Lele Wang Fan Yang Yunshan Chen Junjie Bao Guozheng Zhang Kaiyuan Ji Huishu Liu Guangzhou Key Laboratory of Maternal-Fetal Medicine Department of Obstetrics and GynecologyGuangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangzhouGuangdong 510623China School of Medicine South China University of TechnologyGuangzhouGuangdong 510006China

To the Editor:Spontaneous preterm labor(PTL)causes infant morbidity and *** uterine contractions were the common characteristics in spontaneous labor at term or ***,effective decrease or suppression of myometrial contraction could prevent preterm *** discovered that microRNA-206(miR-206)was a myometrium contraction-associated miRNA based on the transcriptome data of human laboring myometrium and indicated that miR-206 suppressed myometrial contractility by targeting junction protein alpha 1.GJA1.in the myometrium and would be a new potential therapeutic for preterm *** of miR-206 in RU486-induced PTL decreased myometrial contractility,prolonged pregnancy,reversed PTL to term labor,and improved perinatal outcomes.

关键词： mortality contraction RU486

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沸石分子筛在放射性废水处理领域的应用

科学通报 2024年第16期69卷 2221-2232页

作者：郝文峰张佳楠闫文付吉林大学化学学院无机合成与制备化学国家重点实验室长春130012 郑州大学材料科学与工程学院郑州450001

核工业是国家安全的重要基石,体现了国家的综合实力,是大国竞争的战略必争领域.核工业会产生放射性废水,用固态吸附质通过吸附/离子交换的方式可将放射性核素从液相转移到固相,从而实现核废水的减容,是有效处理核废水的方式之一.作为一... 详细信息

核工业是国家安全的重要基石,体现了国家的综合实力,是大国竞争的战略必争领域.核工业会产生放射性废水,用固态吸附质通过吸附/离子交换的方式可将放射性核素从液相转移到固相,从而实现核废水的减容,是有效处理核废水的方式之一.作为一种无机吸附剂,沸石分子筛凭借自身的优异理化性质和稳定性,在放射性废水处理中展现出较好的应用前景,得到越来越多的研究和关注.本文综述了国内外利用天然沸石、合成沸石和改性沸石去除废水中铯、锶、钴、铀、钚、镅、钐和铕等核素的研究进展,希望能为我国放射性废水处理技术的发展提供借鉴和参考;最后展望了未来的研究方向,以期推动沸石材料在工程技术领域的应用.

关键词：沸石分子筛放射性核素离子交换核废水

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大规模外语测试的计算机化演进

外语电化教学 2024年第3期 90-94页

作者：潘鸣威薛文枫上海外国语大学

随着信息技术和人工智能的迅猛发展,大规模外语测试的计算机化已成为主流施考模式之一。但由于考试的特殊性,纸笔考试转向计算机化考试的进程一定程度上受到考生规模、考试实施、涉考数据处理以及考试后效等方面的影响。本文在分析这些... 详细信息

随着信息技术和人工智能的迅猛发展,大规模外语测试的计算机化已成为主流施考模式之一。但由于考试的特殊性,纸笔考试转向计算机化考试的进程一定程度上受到考生规模、考试实施、涉考数据处理以及考试后效等方面的影响。本文在分析这些因素的基础上,聚焦大规模语言测试计算机化的两种模式,即基于计算机和基于互联网的模式,阐释了外语测试计算机化演进中的特征和优势。最后,本文展望了我国大规模外语测试计算机化的发展趋势。

关键词：大规模外语测试基于计算机的考试基于网络的考试

Factors governing formation of todorokite at atmospheric pressure

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Science China Earth Sciences 2005年第10期48卷 1678-1689页

作者： CUI Haojie1. FENG Xionghan1. LIU Fan1. TAN wenfeng1.& HE Jizheng2 1. College of Resources and Environment, Huazhong Agricultural University, Wuhan 430070, China 2. Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 1.0085, China Huazhong Agricultural University Chinese Academy of Sciences

Todorokite commonly occurs in Earth surface environments. The factors governing formation of todorokite, such as reaction temperature, metal ions, dissolved O2 and pH, were investigated in this paper. Results showed that the forming rate of todorokite and its crystallinity decreased with falling reaction temperature, and the effect of temperature was more significant than that of other parameters. Nature of metal ions in the interlayer of buserite precursor and the structure of the buserite precursor obviously affected buserite transformation into todorokite. Weak bonding between the metal ions and MnO6 layer of buserite was favorable to todorokite formation. The rate of todorokite formation was promoted at a lower temperature with appropriate bubbling of O2. The pH in the system slightly influenced the todorokite formation, and todorokite could also be formed in a weak alkali medium or in a slightly acidic medium. Aged buserite pre-cursor more easily form todorokite than the unaged one.

关键词： todorokite, buserite, manganese oxide mineral, atmospheric pressure, transformation.

Transient species and its properties of melatonin

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Science China Chemistry 2006年第4期49卷 308-314页

作者： ZHU Hongping1.2, ZHANG Zhaoxia1.2, ZHAO Hongwei1. WANG wenfeng1.& YAO Side1.1. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201.00, China 2. Graduate University of the Chinese Academy of Sciences, Beijing 1.0049, China Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai China Graduate University of the Chinese Academy of Sciences Beijing China

The photo-physical and photo-chemical properties of melatonin (ML) werestudied by 266 nm laser flash photolysis (LFP). ML undergoes photo-ionization to produce radicalcation of ML (ML^(·+))and hydrated electrons (e_(aq)^-), while excited triplet state ~3ML~* is alsoformed during photolysis. The oxidation via one electron transfer from ML to SO_4^(·+) and thetriplet state of riboflavin (~3RF~*) has been also investigated and the rate constants for theprocess have been determined to be 8.0x1.^9 and 1.4x1.^9 L·mol^(-1.·s^(-1. respectively. Theradical cation of 2,2''-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS^(·+)) scavengingcapacities of melatonin and other antioxidants are compared in this paper.

关键词： melatonin, laser flash photolysis, photoionization, triplet state.

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面孔吸引力对经济决策的影响机制

科学通报 2024年第11期69卷 1447-1460页

作者：尚俊辰张懿倬陈文锋傅小兰东南大学人文学院医学人文学系南京211189 中国人民大学心理学系北京100872 中国科学院心理研究所脑与认知科学国家重点实验室北京100101 中国科学院大学心理学系北京100049

面孔吸引力影响人类的经济决策,人们对高吸引力和低吸引力博弈对象的决策不同.大量研究报告美貌溢价效应,另一些研究则发现美貌惩罚效应.前人提出经济学、社会心理学和进化心理学3个取向来解释面孔吸引力影响决策的原因.经济学取向和社... 详细信息

面孔吸引力影响人类的经济决策,人们对高吸引力和低吸引力博弈对象的决策不同.大量研究报告美貌溢价效应,另一些研究则发现美貌惩罚效应.前人提出经济学、社会心理学和进化心理学3个取向来解释面孔吸引力影响决策的原因.经济学取向和社会心理学取向都只提供了描述性解释,忽略了性别的作用.进化心理学取向则提出更深层次的解释,认为人类对高吸引力面孔的偏好主要受到择偶动机的驱使,且人们更偏爱高吸引力的异性.虽然这3个理论体系的解释层级不同,但并不互斥,它们在预测不存在性别差异的美貌溢价现象时有共同的解释力.电生理研究进一步从决策过程中面孔吸引力的认知加工和对公平以及风险的感知的影响方面揭示面孔吸引力影响经济决策的神经生物学机制,发现高吸引力面孔在决策过程中能诱发较大的晚期正成分,并激活伏隔核、眶额叶皮层、腹侧纹状体等与奖赏加工有关的脑区.未来研究应探究真实经济决策情境中,面孔与嗓音、气味等多通道吸引力的交互作用,建立不同面孔吸引力水平的动态连续变化模型,并将电生理研究与现有理论体系整合,全面阐释吸引力影响经济决策的神经机制,并充分挖掘面孔吸引力影响决策的中介变量和调节变量,为控制招聘等活动中的外貌偏见提供理论依据.

关键词：面孔吸引力经济决策美貌溢价美貌惩罚神经机制

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电极材料对电弧与凹坑形成过程研究

制造技术与机床 2024年第9期 65-70页

作者：鲁文峰李雪芝新疆大学智能制造现代产业学院新疆乌鲁木齐830017

为深入研究短电弧加工(short electric arc machining,SEAM)中单脉冲放电电弧及凹坑形成过程,文章通过高速摄像机和多通道数据采集设备分别对纯钨与紫铜电极单脉冲放电电弧观测与波形进行采集,结合电极表面形貌与凹坑微观形貌分析凹坑... 详细信息

为深入研究短电弧加工(short electric arc machining,SEAM)中单脉冲放电电弧及凹坑形成过程,文章通过高速摄像机和多通道数据采集设备分别对纯钨与紫铜电极单脉冲放电电弧观测与波形进行采集,结合电极表面形貌与凹坑微观形貌分析凹坑形成特点与材料去除机理。研究发现,在低能量放电过程中,紫铜电极电弧绕着电极旋转使体积增大,纯钨电极比紫铜电极电弧更稳定;在高能量放电过程中,电极阴极区两端的电弧紫铜电极凸起,纯钨电极收缩。工具电极金属蒸汽的产生,一方面提高了放电电弧稳定性,另一方面增大了凹坑尺寸;纯钨电极放电能量相比紫铜电极两端更对称。

关键词：短电弧加工单脉冲放电电极材料电弧与凹坑金属蒸汽

Element geochemistry and cleaning potential of the No. 1. coal seam from Antaibao mining district

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Science China Earth Sciences 2005年第12期48卷 2142-2154页

作者： WANG wenfeng1. QIN Yong1. SONG Dangyu2, SANG Shuxun1. JIANG Bo1. ZHU Yanming1.& FU Xuehai1.1. College of Resources & Geosciences, China University of Mining and Technology, Xuzhou 221.08, China 2. State Key Laboratory of Coal Combustion, Huazhong University of Science and Technology, Wuhan 430074, China College of Resources & Geosciences China University of Mining and Technology Xuzhou China State Key Laboratory of Coal Combustion Huazhong University of Science and Technology Wuhan China

Based on the analyses of sulfur and 41.other elements in 8 channel samples of the No. 1. coal seam from Antaibao surface mine, Shanxi, China and 4 samples from the coal preparation plant of this mine, the distribution of the elements in the seam profile, their geo-chemical partitioning behavior during the coal cleaning and the genetic relationships between the both are studied. The conclusions are drawn as follows. The coal-forming environment was probably invaded by sea water during the post-stage of peatification, which results in the fact that the contents of As, Fe, S, etc. associated closely with sea water tend to increase toward the top of the seam, and that the kaolinite changes into illite and montmorillonite in the coal-sublayer near the roof. These elements studied are dominantly associated with kaolinite, pyrite, illite, montmorillonite, etc., of which the As, Pb, Mn, Cs, Co, Ni, etc. are mainly associated with sulfides, the Mo, V, Nb, Hf, REEs, Ta etc. mainly with kaolintie, the Mg, Al etc. mainly with epigenetic montmorillonite, and the Rb, Cr, Ba, Cu, K, Hg, etc. mainly with epigenetic illite. The physical coal cleaning is not only effective in the removal of ash and sulfur, but also in reducing the concentra-tion of most major and trace elements. The elements Be, U, Sb, W, Br, Se, P, etc. are largely or partly organically bound showing a relatively low removability, while the removability of the other elements studied is more than 20%, of which the Mg, Mn, Hg, Fe, As, K, Al, Cs, and Cr associ-ated mostly with the coarser or epigenetic minerals show a higher removability than that of ash. The distribution of the elements in the seam profile controls their partitioning behavior to a great degree during the coal cleaning processes.

关键词： Antaibao mining district, No.1. coal seam, element geochemistry, cleaning.

混合所有制改革对企业创新投入影响的实证研究

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中国软科学 2024年第4期 214-224页

作者：谷方杰汪梦玉张文锋大连海洋大学经济管理学院辽宁大连116023

中国企业改革是实现高质量经济发展的有效途径,其中混合所有制改革对企业创新投入产生了深远影响。选取201.—2022年内1.001.A股上市公司的截面数据为样本,实证研究了混合所有制改革对国有企业和民营企业创新投入的影响。结果显示,混... 详细信息

中国企业改革是实现高质量经济发展的有效途径,其中混合所有制改革对企业创新投入产生了深远影响。选取201.—2022年内1.001.A股上市公司的截面数据为样本,实证研究了混合所有制改革对国有企业和民营企业创新投入的影响。结果显示,混合所有制改革的深度对国有企业的创新投入有显著的负向影响,其制衡度对国有企业的创新投入也存在显著的负向影响。混合股权结构的公司更有助于国有企业增加创新投入,而引入非控股国有股权的民营企业也更有利于增加其创新投入。

关键词：国有企业民营企业创新投入混合所有制改革