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Women’s preconception health patterns in traditional Chinese medicine as a predictor of fertility outcomes

Journal of Integrative Medicine 2020年第3期18卷 222-228页

作者： Xia-qiu Wu wendy Satmary Jin Peng Ka-kit Hui School of Basic Medical Sciences Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Center for East-West Medicine David Geffen School of MedicineUniversity of CaliforniaLos AngelesCA 90024USA Department of Obstetrics&Gynecology David Geffen School of MedicineUniversity of CaliforniaLos AngelesCA 90024USA Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China

Objective: To examine the association between traditional Chinese medicine(TCM), preconception health patterns and fertility ***: A community-based prospective cohort study was conducted in China. A total of 3012 newly married women who were willing to conceive within 2 years were enrolled in the study and took National Free Prepregnancy Checkups(NFPC). A reliably structured self-rating scale was used to measure the TCM preconception health patterns of the enrolled women. A 3-year follow-up was conducted to obtain the fertility outcomes, including pregnancy rate, time to pregnancy, spontaneous miscarriage and newborn status. Statistical analyses were conducted using Chi-square or Fisher’s exact tests, logistic regression models, general linear models and the Cox proportional hazard ***: The fertility outcomes showed no statistic correlations to the terms of NFPC in this *** a half of the women(46.66%) had unhealthy patterns. Women with qi & blood-deficiency(odds ratio [OR] = 35.19, 95% confidence interval [CI] = 1.55–801.15) or qi-stagnation(OR = 4.55, 95% CI =0.90–23.06) pattern took a longer time to get pregnant, and those with qi-stagnation(OR = 2.05, 95% CI =1.1–3.82) or yang-deficiency(OR = 1.91, 95% CI = 1.12–3.25) pattern had a higher risk of spontaneous ***: Three unhealthy TCM patterns during the preconception period might be risk factors for low fecundity or poor pregnancy outcomes. The TCM preconception pattern identification may provide a convenient and effective way to screen for potential pregnancy risks beyond the NFPC. Further, appropriate interventions based on the TCM preconception health patterns are needed to improve quality in women’s fecundability and birth outcomes.

关键词： Preconception care Fertility Traditional Chinese medicine Women’s health Risk assessment

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Anthropometrics,flexibility and training history as determinants for bicycle configuration

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Sports Medicine and Health Science 2021年第2期3卷 93-100页

作者： wendy Holliday Jeroen Swart Department of Human Biology Division of Exercise Science and Sports MedicineUniversity of Cape TownSouth Africa

Intrinsic factors such as leg length,arm length,flexibility and training history are factors that may be relevant to the optimisation of the individual bicycle configuration *** fitting methods do not always take all these variables into account,and as yet there have been limited studies examining how these variables can affect the cyclist's position on the *** main aims of this study were to establish how individual anthropometrics,training history and flexibility may influence cyclists'freely chosen bicycle configuration,and to determine the full-body static flexion angles chosen by cyclists on the *** well-trained male cyclists were recruited for the study.A multivariate linear regression analysis was performed to predict the four main configurations of a bicycle(saddle height,saddle setback,handlebar reach and handlebar drop)based on individual anthropometrics,flexibility and training *** joint kinematic ranges for the knee(36°±7°)and elbow(19°±8°)joint supported previous ***(77°±5°)and shoulder(112°±7°)joint angles should be determined as true clinical *** leg length(p<0.01),Knee Extension Angle test(p<0.01)and mSchober test(p=0.04)were significant predictors for determining saddle *** flexibility can be used to predict handlebar drop(p=0.01).A cyclist who wishes to adopt a more aerodynamic position with an increased handlebar drop should aim to improve their hamstring flexibility.

关键词： Cycling Flexibility Intrinsic factors Bicycle configuration

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Pre-mRNA modifications and their role in nuclear processing

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Frontiers of Electrical and Electronic Engineering in China 2018年第3期6卷 210-227页

作者： Nicole M Martinez wendy V Gilbert Department of Molecular Biophysics ＆ Biochemistry Yale UniversityNew HavenCT 06520USA

Background： Cellular non-coding RNAs are extensively modified post-transcriptionally, with more than 100 chemically distinct nucleotides identified to date. In the past five years, new sequencing based methods have revealed widespread decoration of eukaryotic messenger RNA with diverse RNA modifications whose functions in mRNA metabolism are only beginning to be known. Results： Since most of the identified mRNA modifying enzymes are present in the nucleus, these modifications have the potential to function in nuclear pre-mRNA processing including alternative splicing. Here we review recent progress towards illuminating the role of pre-mRNA modifications in splicing and highlight key areas for future investigation in this rapidly growing field. Conclusions： Future studies to identify which modifications are added to nascent pre-mRNA and to interrogate the direct effects of individual modifications are likely to reveal new mechanisms by which nuclear pre-mRNA processing is regulated.

关键词： mRNA modification pre-mRNA modification splicing RNA-modifying enzymes

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Applications for Nanoscale X-ray Imaging at High Pressure

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Engineering 2019年第3期5卷 479-489页

作者： wendy L. Mao Yu Lin Yijin Liu Jin Liu Department of Geological Sciences Stanford University Stanford CA 94305 USA Stanford Institute for Materials and Energy Sciences SLAC National Accelerator Laboratory Menlo Park CA 94025 USA Stanford Synchrotron Radiation Lightsource SLAC National Accelerator Laboratory Menlo Park CA 94025 USA

Coupling nanoscale transmission X-ray microscopy (nanoTXM) with a diamond anvil cell (DAC) has exciting potential as a powerful three-dimensional probe for non-destructive imaging at high spatial resolution of materials under extreme conditions. In this article, we discuss current developments in high-resolution X-ray imaging and its application in high-pressure nanoTXM experiments in a DAC with third-generation synchrotron X-ray sources, including technical considerations for preparing successful measurements. We then present results from a number of recent in situ high-pressure measurements investigating equations of state (EOS) in amorphous or poorly crystalline materials and in pressureinduced phase transitions and electronic changes. These results illustrate the potential this technique holds for addressing a wide range of research areas, ranging from condensed matter physics and solidstate chemistry to materials science and planetary interiors. Future directions for this exciting technique and opportunities to improve its capabilities for broader application in high-pressure science are discussed.

关键词： X-ray imaging High pressure Diamond anvil cell

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Multiple Antibiotic Resistance and Heavy Metal Resistance Profile of Bacteria Isolated from Giant Freshwater Prawn (Macrobrachium rosenbergii) Hatchery

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Agricultural Sciences in China 2009年第6期8卷 740-745页

作者： S W Lee M Najiah W wendy A Zahrol M Nadirah Department of Fishery and Aquaculture Faculty of Agrotechnology and Food Science Universiti Malaysia Terengganu

In this article, antibiogram and heavy metal resistance profile of bacteria isolated from giant freshwater prawn （Macrobrachium rosenbergii） hatchery in Malaysia are described. Although giant freshwater prawn was introduced into Malaysia since the 1980s, there was no database information on antibiogram and heavy metal resistance profile of bacteria from giant freshwater prawn （34. rosenbergii） hatchery in Malaysia. Therefore, this study was carried out to determine the effectiveness of antibiotic and heavy metal resistance profile to control bacterial diseases in M. rosenbergii hatchery. The results can provide valuable information for local M. rosenbergii post-larval producer. Antibiotic sensitivity test was carried out by disk-diffusion method against 15 types of antibiotics as follows： oxolinic acid （2 μg）, ampicillin （10μg）, erythromycin （15μg）, furazolidone （15 μg）, lincomycin （15μg）, amoxicillin （25 μg）, colistin sulphate （25 μg）, doxycycline （30μg）, florfenicol （30 μg）, flumequine （30 lag）, nalidixic acid （30μg）, tetracycline （30μg）, oleandomycin （15μg）, fosfomycin （50μg）, and spiramycin （100 μg）, whereas heavy metal resistance profile of the present bacterial isolates was determined by 2-fold agar dilution technique. In this study, 5 types of bacteria were successfully isolated; they were Aeromonas spp. （n = 77）, Escherichia coli （n = 73）, Edwardsiella spp. （n = 62）, Salmonella spp. （n = 75）, and Vibrio spp. （n = 43）. The result showed that furazolidone was the most effective antibiotic to control the bacteria isolated in this study, approximately 89.7% of the bacterial isolates were sensitive to this antibiotic. Multiple antibiotic resistance （MAR） index indicated that the hatchery water source and M. rosenbergii post-larval and sediment tanks were at high-risk exposure to the tested antibiotic. Furthermore, all the tested heavy metals （Cd2＋, Cr6＋, Hg2＋, and Cu2＋） failed to inhibit the growth of the bacterial isolates. Therefore, it indicated that the water

关键词： Macrobrachium rosenbergii hatchery antibiotic heavy metal MAR index

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Does overshoot in leaf development of ponderosa pine in wet years leads to bark beetle outbreaks on fine-textured soils in drier years?

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Forest Ecosystems 2014年第4期1卷 214-226页

作者： wendy Peterman Richard H Waring Conservation Biology Institute Department of Forest Ecosystems and Society Oregon State University

Background： Frequent outbreaks of insects and diseases have been recorded in the native forests of western North America during the last few decades, but the distribution of these outbreaks has been far from uniform. In some cases, recent climatic variations may explain some of this spatial variation along with the presence of expansive forests composed of dense, older trees. Forest managers and policy makers would benefit if areas especially prone to disturbance could be recognized so that mitigating actions could be taken. Methods： We use two ponderosa pine-dominated sites in western Montana, U.S.A. to apply a modeling approach that couples information acquired via remote sensing, soil surveys, and local weather stations to assess where bark beetle outbreaks might first occur and why. Although there was a general downward trend in precipitation for both sites over the period between 1998 and 2010 （slope =-1.3, R2 = 0.08）, interannual variability was high. Some years showed large increases followed by sharp decreases. Both sites had similar topography and fire histories, but bark beetle activity occurred earlier （circa 2000 to 2001） and more severely on one site than on the other. The initial canopy density of the two sites was also similar, with leaf area indices ranging between 1.7-2.0 m2. m-2. We wondered if the difference in bark beetle activity was related to soils that were higher in clay content at site I than at site II. To assess this possibility, we applied a process-based stand growth model （3-PG） to analyze the data and evaluate the hypotheses. Results： We found that when wet years were followed by drier years, the simulated annual wood production per unit of leaf area, a measure of tree vigor, dropped below a critical threshold on site I but not on site II. Conclusion： We concluded that the difference in vulnerability of the two stands to beetle outbreaks can be explained largely by differences in gross photosynthesis attributed to the fact that an equ

关键词： Does overshoot in leaf development of ponderosa pine in wet years leads to bark beetle outbreaks on fine-textured soils in drier years soil

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Understanding the management of brachial plexus birth palsy and the roles of nerve transfers

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Plastic and Aesthetic Research 2023年第1期10卷 451-462页

作者： wendy Chen Ryan Keyho Idris Gharboui Department of Plastic and Reconstructive Surgery UT Houston McGovern Medical SchoolHoustonTX 77030USA

Early recognition and management of neonatal brachial plexus injury(NBPP)is key to optimizing outcomes and surgical *** up to a third of patients with birth palsy may require surgical intervention,the multidisciplinary team must follow up on the function and recovery of the entire upper extremity,from shoulder to fingertips,within the first few months of *** include neuroma resection and primary nerve grafting and/or nerve transfers,which can be intra-or extra-plexal,as adjunctive or standalone *** limited proximal nerve roots are available for nerve grafting,or when too many nerve roots are involved,exceeding the supply of nerve graft,extra-plexal nerve transfers are then *** early intervention is preferred(between 3 and 6 months for most authors),older children presenting late(>1 year since birth)with partial nerve recovery may still potentially benefit from nerve transfers,which can be offered to late-presenting *** we discuss the anatomy,indications,work-up,options,complications,and outcomes for such nerve transfers for upper,lower,and global plexus palsy in *** transfers are a common procedure done for the treatment of various types of birth plexus ***,while there is an abundance of clinical reports and evidence,there is still a lack of clarity regarding best practices or in terms of the type of procedure and technique for the treatment of birth plexus *** hope is that this chapter provides a concise source after an extensive cumulative review of the evidence of best practices for nerve transfers in the case of birth plexus palsy.

关键词： Neonatal birth plexus palsy brachial plexus nerve transfer birth palsy

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Hydrogeochemical modelling of corrosive environment contributing to premature failure of anchor bolts in underground coal mines

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Journal of Central South University 2020年第5期27卷 1599-1610页

作者： PENG Ya wendy TIMMS School of Civil and Resource Engineering University of Science and Technology BeijingBeijing 100083China School of Minerals and Energy Resources Engineering UNSW SydneySydney 2052Australia Faculty of Science Engineering&Built Environment Deakin UniversityGeelong 3216Australia

Anchor bolts are commonly used throughout underground mining and tunnelling operations to improve roof ***,premature failures of anchor bolts are significant safety risks in underground excavations around the world due to susceptible bolt materials,a moist and corrosive environment and tensile *** this paper,laboratory experiments and hydrogeochemical models were combined to investigate anchor bolt corrosion and failure associated with aqueous environments in underground coal *** data and collated mine water chemistry data were used to simulate bolt corrosion reactions with groundwater and rock materials with the PHREEQC code.A series of models quantified reactions involving iron and carbon under aerobic and anaerobic conditions in comparison with ion,pH and pE trends in experimental *** models showed that corrosion processes are inhibited by some natural environmental factors,because dissolved oxygen would cause more iron from the bolts to oxidize into *** interdisciplinary insights into corrosion failure of underground anchor bolts confirm that environmental factors are important contributors to stress corrosion cracking.

关键词： anchor bolts hydrogeochemical modelling rock bolts and cable bolts stress corrosion cracking water chemistry analysis

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Critics, coteries, and Pre-Raphaelite celebrity

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作者： wendy Graham.

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The notorious Mrs. Clem

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作者： (1958-)Gamber wendy

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