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Science China(Information Sciences) 2021年第11期64卷 207-215页

作者： wenbo guo Yimin HE Hongzhi ZHAO Shihai SHAO Youxi TANG National Key Laboratory of Science and Technology on Communications University of Electronic Science and Technology of China

For the security of wireless communications, cooperative jamming can be used to intentionally degrade the signal-to-noise ratios received by eavesdroppers. Unfortunately, this jamming may also propagate to the legal receiver and then become a harmful self-interference(SI), which should be cancelled for reliable detection of the desired signal. In this paper, by comprehensively considering nonideal time-frequency alignment and channel equalization, SI-cancellation capability is investigated for the additive white Gaussian noise channel. Theoretical and simulation results demonstrated that the impact of the frequency alignment error is more serious than that of the time alignment and channel equalization errors. Moreover, it is illustrated that weaker SI power can tolerate a larger range of those nonidealities.

关键词： cooperative jamming self-interference time-frequency alignment channel equalization non-idealities

6-DOF MOTION AND CENTER OF ROTATION ESTIMATION BASED ON STEREO VISION

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Chinese Journal of Mechanical Engineering 2008年第2期21卷 87-92页

作者： CAO Wanpeng BI Wei CHE Rensheng guo wenbo YE Dong Department of Automatic Measurement and Control Harbin Institute of Technology Harbin 150001 China China Academy of Machinery Science and Technology Beijing 100044 China Department of Electrical Engineering and Automation Harbin Institute of Technology Harbin 150001 China

A new motion model and estimation algorithm is proposed to compute the general rigid motion object＇s 6-DOF motion parameters and center of rotation based on stereo vision. The object＇s 6-DOF motion model is designed from the rigid object＇s motion character under the two defined reference frames. According to the rigid object＇s motion model and motion dynamics knowledge, the corresponding motion algorithm to compute the 6-DOF motion parameters is worked out. By the rigid object pure rotation motion model and space sphere geometry knowledge, the center of rotation may be calculated after eliminating the translation motion out of the 6-DOF motion. The motion equations are educed based on the motion model and the closed-form solutions are figured out. To heighten the motion estimation algorithm＇s robust, RANSAC algorithm is applied to delete the outliers. Simulation and real experiments are conducted and the experiment results are analyzed. The results prove the motion model＇s correction and algorithm＇s validity.

关键词： Motion estimation Center of rotation 6-DOF motion Stereo vision

Analysis and Compensation of Frequency Offset in Co-Site Adjacent Channel Interference Suppression

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China Communications 2023年第6期20卷 116-128页

作者： Xiaolei Huo wenbo guo Ying Liu Hongzhi Zhao Youxi Tang National Key Laboratory of Science and Technology on Communications University of Electronic Science and Technology of ChinaChengdu 611731China Department of Electronic and Optical Engineering Shijiazhuang Campus of Army Engineering UniversityShijiazhuang 050003China

Due to the mismatch of the circuit oscillators,there will always be a frequency offset between the transmitter and the *** the adjacent channel interference(ACI)suppression system using the reconstruction and cancellation method,the frequency offset decreases the accuracy of the reconstructed signal and introduces a time-varying term in the interference cancellation,resulting in poor performance of the ACI *** this paper,the relationship between the normalized frequency offset,signal-to-noise ratio and the loss of interference suppression capability is analyzed through formula derivation and *** validity of the frequency offset compensation method based on the pilot sequence is verified,and the relationship between the sequence length and the estimation accuracy is *** paper provides necessary method reference and data support for the engineering of ACI suppression.

关键词： ACI non-linear distortion parameter estimation interference suppression

A sea change in statistics:A reconsideration of what is important in the age of big data

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Journal of Management Analytics 2014年第4期1卷 241-248页

作者： wenbo guo Detmar Straub Pengzhu Zhang Antai College of Economics and Management Shanghai Jiao Tong UniversityShanghai 200052China J.Mack Robinson College of Business Georgia State UniversityAtlantaGA 30303USA

The development of information technology(IT)in the last decade has ushered us into the‘big data’*** sampling error has been of high interest in such studies over the last century,extremely large datasets will virtually rule out the possibility that statistics generated from samples are not also true of the *** critical discussion must move on to how much the exogenous and endogenous variables explain ultimate *** stress will have to move from generalizability to explanatory *** examining the three common statistical tests–the T-value,the F-value and the beta coefficient(or‘b’in the sample)–this paper aims to show how important effect size analysis is with the trend toward larger and larger samples and big *** the end,the paper points out the gap of what the acceptable ranges of effects that appears in our sundry scientific literatures *** call for studies in this regard so that social sciences can move forward and strengthen weak theory bases,and recognize strong theories when they do appear.

关键词： p-value effect size sample size big data

Laser capture microdissection for biomedical research: towards high-throughput, multi-omics, and single-cell resolution

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Journal of Genetics and Genomics 2023年第9期50卷 641-651页

作者： wenbo guo Yining Hu Jingyang Qian Lidan Zhu Junyun Cheng Jie Liao Xiaohui Fan Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang 310058China National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxingZhejiang 314100China

Spatial omics technologies have become powerful methods to provide valuable insights into cells and tissues within a complex context,significantly enhancing our understanding of the intricate and multifaceted biological *** an increasing focus on spatial heterogeneity,there is a growing need for unbiased,spatially resolved omics *** capture microdissection(LCM)is a cutting-edge method for acquiring spatial information that can quickly collect regions of interest(ROIs)from heterogeneous tissues,with resolutions ranging from single cells to cell ***,LCM has been widely used for studying the cellular and molecular mechanisms of *** review focuses on the differences among four types of commonly used LCM technologies and their applications in omics and disease *** attributes of application cases are also highlighted,such as throughput and spatial *** addition,we comprehensively discuss the existing challenges and the great potential of LCM in biomedical research,disease diagnosis,and targeted therapy from the perspective of high-throughput,multi-omics,and single-cell resolution.

关键词： Laser capture microdissection Spatial omics Single-cell resolution Multiplexed barcoding Disease microenvironment

TIST: Transcriptome and Histopathological Image Integrative Analysis for Spatial Transcriptomics

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Genomics, Proteomics & Bioinformatics 2022年第5期20卷 974-988页

作者： Yiran Shan Qian Zhang wenbo guo Yanhong Wu Yuxin Miao Hongyi Xin Qiuyu Lian Jin Gu MOE Key Laboratory of Bioinformatics BNRIST Bioinformatics DivisionDepartment of AutomationTsinghua UniversityBeijing 100084China UM-SJTU Joint Institute Shanghai Jiao Tong UniversityShanghai 200240China Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China

Sequencing-based spatial transcriptomics(ST)is an emerging technology to study in situ gene expression patterns at the whole-genome ***,ST data analysis is still complicated by high technical noises and low *** addition to the transcriptomic data,matched histopathological images are usually generated for the same tissue sample along the ST *** matched high-resolution histopathological images provide complementary cellular phenotypical information,providing an opportunity to mitigate the noises in ST *** present a novel ST data analysis method called transcriptome and histopathological image integrative analysis for ST(TIST),which enables the identification of spatial clusters(SCs)and the enhancement of spatial gene expression patterns by integrative analysis of matched transcriptomic data and *** devises a histopathological feature extraction method based on Markov random field(MRF)to learn the cellular features from histopathological images,and integrates them with the transcriptomic data and location information as a network,termed *** on TIST-net,SCs are identified by a random walk-based strategy,and gene expression patterns are enhanced by neighborhood *** benchmark TIST on both simulated datasets and 32 real samples against several state-of-the-art *** show that TIST is robust to technical noises on multiple analysis tasks for sequencing-based ST data and can find interesting microstructures in different biological *** is available at http://***/software/tist/and https://***/biocode/tools/BT007317.

关键词： Spatial transcriptomics Multimodal information integration Network-based analysis Spatial cluster identification Gene expression enhancement

Highly Regional Genes:graph-based gene selection for single-cell RNA-seq data

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Journal of Genetics and Genomics 2022年第9期49卷 891-899页

作者： Yanhong Wu Qifan Hu Shicheng Wang Changyi Liu Yiran Shan wenbo guo Rui Jiang Xiaowo Wang Jin Gu MOE Key Laboratory of Bioinformatics BNRIST Bioinformatics DivisionDepartment of AutomationTsinghua UniversityBeijing 100084China

Gene selection is an indispensable step for analyzing noisy and high-dimensional single-cell RNA-seq(scRNA-seq)*** with the commonly used variance-based methods,by mimicking the human maker selection in the 2D visualization of cells,a new feature selection method called HRG(Highly Regional Genes)is proposed to find the informative genes,which show regional expression patterns in the cell-cell similarity *** mathematically find the optimal expression patterns that can maximize the proposed scoring *** comparison with several unsupervised methods,HRG shows high accuracy and robustness,and can increase the performance of downstream cell clustering and gene correlation ***,it is applicable for selecting informative genes of sequencing-based spatial transcriptomic data.

关键词： Single-cell RNA-sequencing Feature selection Spatially resolved transcriptomic data Regional patterns Graphical models

Genesis of the Sinongduo Carbonate-hosted Pb-Zn-Ag Deposit in the Central Lhasa Terrane,Tibet

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Acta Geologica Sinica(English Edition) 2023年第3期97卷 759-776页

作者： RAN Fengqin TANG Juxing YANG Zongyao DUO Ji REN Dongxing guo wenbo WU Xin HAO Jinyue HE Yifei SUN Yang College of Earth Science Chengdu University of TechnologyChengdu 610059China MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological ScienceBeijing 100037China Chengdu Surveying Geotechnical Research Institute Co. Ltd.of MCCChengdu 610023China Chengdu Engineering Corporation Limited PowerChinaChengdu 611130China New Energy Geology Team of the Hebei Coalfield Geology Bureau XingtaiHebei 054000China

The Sinongduo mining region includes two types of mineralizations:the epithermal and the carbonate-hosted PbZn-Ag *** being studied for many years,the ore formation process and genesis of the carbonate-hosted Pb-Zn-Ag deposits remain poorly *** Pb-Zn-Ag ore bodies occur as veins and are hosted by limestone and dolostone of the Permian Xiala *** sulfide mineralization substages have been identified at the Sinongduo carbonatehosted *** coupled with Cu,Co and Sn was incorporated into sphalerite as substitutions:2Zn^(2+)?Cu^(+)+In^(3+),(3n/2+1)Zn^(2+)?Co^(2+)+n In^(3+)or(2n+1)Zn^(2+)?Co^(2+)+n(Cu^(+)+In^(3+))(n>1)and 4Zn^(2+)?Sn2++2In^(3+).Sphalerite and pyrite in the mineralization stage displayδ^(34)S values in a narrow range of+5.7‰to+11.3‰,which are similar to those of Palaeocene igneous rocks,indicative of a magmatic source of *** present systematic carbon-hydrogen-oxygen isotope results that further support a magmatic source for the ore-forming fluids that were influenced by meteoric ***,the Pb isotope compositions of sulfide minerals in the Sinongduo carbonate-hosted deposit overlap with the values of coeval Linzizong volcanic rocks and are similar to those of Indian Ocean sediments,indicating upper crustal sources of *** conclude that the Sinongduo carbonate-hosted Pb-Zn-Ag deposit is a medium-to low-temperature magmatic-hydrothermal deposit related to Linzizong magmatism.

关键词： sulfur and lead isotopes sphalerite carbonate-hosted deposit Tibet India–Asia collision

High-speed and high-efficiency three-dimensional shape measurement based on Gray-coded light

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Photonics Research 2020年第6期8卷 819-829页

作者： ZHOUJIE WU wenbo guo YUEYANG LI YIHANG LIU QICAN ZHANG Department of Opto-Electronics Sichuan UniversityChengdu 610065China

Fringe projection profilometry has been increasingly sought and applied in dynamic three dimensional(3D)shape *** this work,a robust,high-efficiency 3D measurement based on Gray-coded light is *** the traditional method,a tripartite phase unwrapping method is proposed to avoid the jump errors on the boundary of code words,which are mainly caused by the defocusing of the projector and the motion of the tested ***,the time overlapping coding strategy is presented to greatly increase the coding ef-ficiency,decreasing the projected number in each group from seven(i.e.,3+4)to four(i.e.,3+1)for one restored 3D *** combination of two proposed techniques allows the reconstruction of a pixel-wise and unambiguous 3D geometry of dynamic scenes with strong noise using every four projected *** the best of our knowledge,the presented techniques for the first time preserve the high anti-noise ability of a method based on the Gray code while overcoming the drawbacks of jump errors and low coding *** have demonstrated that the proposed method can achieve robust,high efficiency 3D shape measurement of high speed dynamic scenes even polluted by strong noise.

关键词： dimensional light projection

Self-assembled natural phytochemicals for synergistically antibacterial application from the enlightenment of traditional Chinese medicine combination

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Acta Pharmaceutica Sinica B 2020年第9期10卷 1784-1795页

作者： Xuehao Tian Penglong Wang Tong Li Xuemei Huang wenbo guo Yuqin Yang Mengmeng Yan Hao Zhang Desheng Cai Xiaohui Jia Feifei Li Bing Xu Tao Ma Cong Yan Haimin Lei School of Chinese Pharmacy Beijing University of Chinese MedicineBeijing 102488China School of Life Science Beijing University of Chinese MedicineBeijing 102488China

The application of nanotechnology for antimicrobial delivery has capacity to improve anti-bacterial ***,the usage of various inorganic and organic carriers,such as metal ions,nano-silicon and surfactants,might increase the potential toxicity of nanoparticles and make their clinical transformation more ***,a nano-delivery system was constructed by direct self-assembly of antibacterial phytochemicals(berberine and rhein)originated from traditional Chinese medicine Coptis chinensis *** Rheum palmatum L.,*** X-ray single crystal diffraction,nuclear magnetic resonance and other spectra characterizations,the stacked structure of nanoparticles was profoundly ***,rhein acted as the layered backbone and berberine embedded in *** vitro bacteriostasis experiment showed the minimum bactericidal concentration of nanoparticles was 0.1μmol/mL,which was lower than that of berberine and *** results of confocal laser scanning microscope,biofilm quantitive assay and scanning electron microscopy indicated that nanoparticles had strong inhibitory effects on Staphylococcus aureus *** importantly,transmission electron microscopy and mass spectra indicated the further bacteriostatic mechanism of ***,the nanoparticles had well biocompatibility and *** study will open up new prospect that the design of self-assemblies between active phytochemicals can be originated from traditional Chinese medicine combination.

关键词： Natural phytochemicals Self-assembly Antibacterial Synergistic effect Staphylococcus aureus Traditional Chinese medicine