检索结果-南通市图书馆

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

外用鱼油促进2型糖尿病大鼠伤口创面的愈合

陆军军医大学学报 2024年第6期46卷 535-543页

作者：黄荣江辛文彬倪向敏李正宙张贵明王建陆军军医大学(第三军医大学)第二附属医院营养科重庆400037

目的观察局部外用鱼油对2型糖尿病(diabetes mellitus type 2, T2DM)大鼠伤口创面愈合的影响,并探讨其作用机制。方法 57只SD大鼠通过高脂高糖饮食联合STZ腹腔注射建立T2DM大鼠模型,建模成功49只。T2DM大鼠模型建立成功后通过外科方法... 详细信息

目的观察局部外用鱼油对2型糖尿病(diabetes mellitus type 2, T2DM)大鼠伤口创面愈合的影响,并探讨其作用机制。方法 57只SD大鼠通过高脂高糖饮食联合STZ腹腔注射建立T2DM大鼠模型,建模成功49只。T2DM大鼠模型建立成功后通过外科方法创建伤口创面模型,采用随机数字表法分为鱼油组(n=17)、玉米油组(n=16)、模型对照组(n=16),各组于创面模型创建后次日开始给药,干预期间观察各组大鼠伤口创面愈合情况,分别于术后7、14 d取皮肤创面组织比较大鼠创面愈合情况,检测氧化应激指标(MDA、SOD、CAT)及炎症因子(TNF-α、IL-1β、IL-6、IL-10)水平,HE、Masson染色行病理学分析及观察皮肤真皮层胶原纤维沉积情况,Western blot检测SIRT1、Nrf2、NQO1蛋白表达。结果与玉米油组和模型对照组相比,术后第7、14天鱼油组大鼠伤口创面愈合率明显提升(P<0.05),胶原纤维沉积增多;创面组织MDA、TNF-α、IL-1β、IL-6水平明显下降(P<0.05),而SOD、CAT、IL-10水平显著升高(P<0.05);Western blot结果显示,鱼油组大鼠创面组织SIRT1、Nrf2、NQO1蛋白表达水平较玉米油组和模型对照组显著提升(P<0.05);干预期间玉米油组与模型对照组间愈合效果无显著差异。结论局部外用鱼油可有效促进T2DM大鼠伤口创面愈合,其机制可能与鱼油降低创面组织氧化应激及炎症反应有关。

关键词：鱼油糖尿病伤口氧化应激炎症反应沉默信息调节因子1(SIRT1)

Nb含量对V-Ti-N工程结构用钢连续冷却转变规律及组织性能的影响

在线全文

学校读者我要写书评

暂无评论

金属热处理 2024年第3期49卷 236-244页

作者：童炀张婧辛文彬罗果萍彭军侯蹬云内蒙古科技大学稀土产业学院(稀土工程技术学院) 内蒙古包头014010

利用淬火膨胀仪DIL-805研究了Nb-V-Ti-N微合金钢的连续冷却转变规律,并探讨了Nb含量对钢组织和性能的影响。结果表明,当冷速由0.1℃/s增大至30℃/s时,发生过冷奥氏体向铁素体、珠光体、贝氏体和马氏体转变,冷速范围分别为0.1~20、0.1~5... 详细信息

利用淬火膨胀仪DIL-805研究了Nb-V-Ti-N微合金钢的连续冷却转变规律,并探讨了Nb含量对钢组织和性能的影响。结果表明,当冷速由0.1℃/s增大至30℃/s时,发生过冷奥氏体向铁素体、珠光体、贝氏体和马氏体转变,冷速范围分别为0.1~20、0.1~5、1~30和10~30℃/s,且铁素体、珠光体和贝氏体的转变温度随冷速的增大而降低,而马氏体转变温度升高;当Nb含量由0.05%(质量分数)增加到0.10%时,奥氏体中Nb的固溶量增加,CCT曲线略向下移动,Ac1和Ac3温度均有所提高。试验钢的显微硬度随冷速的增加不断增大,且当冷速为1~20℃/s时,0.10%Nb试验钢的显微硬度高于0.05%Nb试验钢。这主要取决于钢中硬化相的占比、组织的细化程度及碳氮化物的析出。此外,高温奥氏体区析出的亚微米级富Nb碳氮化物不仅能够钉扎晶界而且可作为异质形核核心诱导晶内铁素体的形成,二者共同作用细化组织,提升强韧性。

关键词： Nb-V-Ti-N微合金钢 CCT曲线 Nb含量组织演变显微硬度

在线全文

学校读者我要写书评

暂无评论

靶向肿瘤免疫微环境放射性药物研究进展

中华核医学与分子影像杂志 2024年第9期44卷 559-563页

作者：朱凯刘彩云辛文斌刘婷婷王旭滨州医学院附属医院核医学科滨州256603 滨州医学院附属医院医学研究中心滨州256603

免疫治疗在肿瘤治疗领域取得了突破性的进展。如何在早期精确预测肿瘤患者对免疫治疗的响应是目前临床所面临的挑战。核医学分子影像为疾病的早期精确诊断、治疗监测, 复发和转移预警以及个体化治疗指导提供了崭新的技术手段, 因此在肿... 详细信息

免疫治疗在肿瘤治疗领域取得了突破性的进展。如何在早期精确预测肿瘤患者对免疫治疗的响应是目前临床所面临的挑战。核医学分子影像为疾病的早期精确诊断、治疗监测, 复发和转移预警以及个体化治疗指导提供了崭新的技术手段, 因此在肿瘤的精准诊治及患者分层中发挥着不可替代的作用。该文综述针对肿瘤微环境内免疫细胞和相关靶点的分子影像研究进展。

关键词：放射性药物免疫疗法肿瘤微环境发展趋势

Mo对Nb-V-N微合金钢复合碳氮化物析出行为的影响

在线全文

学校读者我要写书评

暂无评论

钢铁 2024年第8期59卷 104-116页

作者：侯蹬云张婧辛文彬赵志博彭军童炀内蒙古科技大学稀土产业学院(稀土工程技术学院) 内蒙古包头014010

钢中微合金碳氮化物的析出行为与其强度直接相关,为揭示Nb-V-Mo-N四元微合金钢中MX(M为Nb、V、Mo,X为C、N)复合碳氮化物的析出规律,通过Thermo-Calc热力学计算软件分析了平衡条件下不同Mo含量微合金钢的析出热力学相图,MX第二相在奥氏... 详细信息

钢中微合金碳氮化物的析出行为与其强度直接相关,为揭示Nb-V-Mo-N四元微合金钢中MX(M为Nb、V、Mo,X为C、N)复合碳氮化物的析出规律,通过Thermo-Calc热力学计算软件分析了平衡条件下不同Mo含量微合金钢的析出热力学相图,MX第二相在奥氏体和铁素体基体相中的析出驱动力、界面能及合金元素在奥氏体中的固溶规律,并利用场发射扫描电镜、透射电镜及电子探针研究了非平衡条件下试验钢中MX碳氮化物的析出特征。结果表明,0Mo钢中MX碳氮化物主要有FCC_A1#1富Nb高温析出相和FCC_A1#2富V中温析出相,0.26Mo和0.50Mo钢则在此基础上增加了MC_ETA即(V,Mo)C低温析出相;当Mo质量分数由0增加到0.50%时,FCC_A1#1和FCC_A1#2相的析出温度和最大析出量变化不明显,但有利于MC_ETA相析出。非平衡条件下,高温奥氏体区析出的富Nb-MX亚微米颗粒能够在钉扎晶界的同时,异质形核诱导针状铁素体形成;中温(奥氏体+铁素体)两相区相间析出和低温铁素体区任意析出的富V-MX纳米颗粒可与位错相互作用,有效阻碍其运动。此外,0Mo试验钢的室温组织由块状铁素体和珠光体组成,当Mo质量分数由0增加到0.26%时,钢中块状铁素体和珠光体所占比例减少,但促进了针状铁素体和少量贝氏体形成,当Mo质量分数进一步增加到0.50%时,铁素体占比明显减少而贝氏体增多;铁素体晶粒尺寸由(10.2±0.42)μm不断细化至(6.7±0.42)μm。试验钢的显微硬度由(223±13.8)HV0.1逐渐增大至(318±19.9)HV0.1,屈服强度和抗拉强度分别由(496±5.3)MPa和(618±9.7)MPa提高至(554±6.7)MPa和(823±13.3)MPa。通过发挥Nb-V-Mo-N四元微合金体系中各合金元素的协同作用,优化MX碳氮化物的析出,有利于提升工程结构用钢的强度。

关键词： Nb-V-Mo-N微合金体系工程结构用钢 MX复合碳氮化物显微组织力学性能

MobileNetV3-CenterNet:A Target Recognition Method for Avoiding Missed Detection Effectively Based on a Lightweight Network

在线全文

学校读者我要写书评

暂无评论

Journal of Beijing Institute of Technology 2023年第1期32卷 82-94页

作者： Yajing Li Xiaoyan Xiong wenbin xin Jiahai Huang Huimin Hao School of Taiyuan University of Technology Taiyuan 030000China

To solve the problems in online target detection on the embedded platform,such as high missed detection rate,low accuracy,and slow speed,a lightweight target recognition method of MobileNetV3-CenterNet is *** method combines the anchor-free Centernet network with the MobileNetV3 small network and is trained on the University at Albany Detection and Tracking(UA-DETRAC)and the Pattern Analysis,Statical Modeling and Computational Learn-ing Visual Object Classes(PASCAL VOC)07+12 standard *** reducing the scale of the network model,the MobileNetV3-CenterNet model shows a good balance in the accuracy and speed of target recognition and effectively solves the problems of missing detection of dense and small targets in online *** verify the recognition performance of the model,it is tested on 2683 images of the UA-DETRAC and PASCAL VOC 07+12 datasets,and compared with the analysis results of CenterNet-Deep Layer Aggregation(DLA)34,CenterNet-Residual Network(ResNet)18,CenterNet-MobileNetV3-large,You Only Look Once vision 3(YOLOv3),MobileNetV2-YOLOv3,Single Shot Multibox Detector(SSD),MobileNetV2-SSD and Faster region convolutional neural network(RCNN)*** results show that the MobileNetV3-CenterNet model accurately rec-ognized the dense targets and small targets missed by other methods,and obtained a recognition accuracy of 99.4%with a running speed at 53(on a server)and 14(on an ipad)frame/s,*** MobileNetV3-CenterNet lightweight target recognition method will provide effective technical support for the target recognition of deep learning networks in embedded platforms and online detection.

关键词： target detection MobileNetV3 CenterNet lightweight

Origin and evolution of false brinelling and fretting corrosion under rolling conditions

在线全文

学校读者我要写书评

暂无评论

Friction 2024年第4期12卷 618-631页

作者： xin JIA Lu HUANG Miao SUN wenbin LI National Institute of Metrology Beijing 100029China Yantai Tiancheng Machinery Co. Ltd.Yantai 264006China

Rolling bearings working in oscillating applications often suffer from false brinelling and fretting corrosion that limit their service *** present,the study of oscillation-induced failures is primarily dominated by a large number of sliding and bench ***,most of the previous work are not able to fully describe the two closely related but different failure *** this study,the origin and evolution of the two failures are thoroughly investigated under strictly controlled oscillating rolling *** results show that failure evolves from false brinelling to fretting corrosion under dry friction conditions regardless of the oscillation *** process is accompanied by a large area peeling and serious oxidation,and the oxygen content increases from 2.50 wt%to 21.22 wt%.Oxidation is a crucial factor in the evolution of false brinelling into fretting ***,the distribution of microwear and oxygen content depend on the oscillation *** lubrication conditions,the friction coefficient(COF)is smaller in the initial stage and led to local slip or transient instability of rolling ***,the size of the wear marks and COF increased and appeared to be larger than those under a dry friction ***,grease can separate the contact surfaces,only surface deformation owing to false brinelling and slight damage at the roughness level *** evolution of false brinelling and fretting corrosion is also closely related to residual *** brinelling often occurrs with residual stress accomulation,meanwhile,the residual stress increases from 120 to 300 *** peeling occurs,residual stress is *** failure pattern transformed from false brinelling to fretting corrosion and is accompanied by *** far,none of investigation is able to show satisfactory evolution of oscillating-induced failures,this study may contribute to more scientific understanding of rolling bearings against long-

关键词： oscillating false brinelling fretting corrosion wear residual stress

Comparative Analysis of Diagonal and Centrifugal Compressors with Synergy Theory in Compressed Air Energy Storage System

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第4期33卷 1325-1339页

作者： ZHANG Yuxin ZUO Zhitao ZHOU xin GUO wenbin CHEN Haisheng Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China National Energy Large Scale Physical Energy Storage Technologies R&D Center of Bijie Bijie551700China Nanjing Institute of Future Energy System IETCASNanjing211135China

Energy storage technology is an essential part of the efficient energy *** air energy storage(CAES)is considered to be one of the most promising large-scale physical energy storage *** is favored because of its low-cost,long-life,environmentally friendly and low-carbon *** compressor is the core component of CAES,and the performance is critical to the overall system *** importance is not only reflected in the design point,but also in the continuous efficient operation under variable working *** diagonal compressor is currently the focus of the developing large-scale CAES because of its stronger flow capacity compared with traditional centrifugal *** the diagonal compressor has the higher single stage pressure ratio compared with axial *** this paper,the full three dimensional numerical simulation technologies with synergy theory are used to compare and analyze the internal flow *** performance of the centrifugal and diagonal impellers that are optimized under the same requirements for large-scale CAES has been *** relationship between the internal flow characteristics and performance of the centrifugal and diagonal impellers with the change of mass flow rates and total inlet temperature is given qualitatively and *** the cosine value of the synergy angle is high,the local flow loss is *** smaller proportion of the positive area is the pursuit of *** comparative analysis,it is concluded that the internal flow and performance changes of centrifugal and diagonal impellers are *** results confirm the superiority and feasibility of the off-design performance of the diagonal compressor applied to the developing large-scale CAES.

关键词： compressed air energy storage synergy theory diagonal compressor centrifugal compressor comparative analysis

Contrast Enhancement Using Weighted Coupled Histogram Equalization with Laplace Transform

在线全文

学校读者我要写书评

暂无评论

Journal of Harbin Institute of Technology(New Series) 2022年第4期29卷 32-40页

作者： Huimin Hao wenbin xin Minglong Bu He Wang Yuan Lan Xiaoyan Xiong Jiahai Huang College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan 030024China Harbin Electric Machinery Company Limited Harbin 150040China

Histogram equalization is a traditional algorithm improving the image contrast,but it comes at the cost of mean brightness shift and details *** order to solve these problems,a novel approach to processing foreground pixels and background pixels independently is proposed and *** details are mainly contained in the foreground,the weighted coupling of histogram equalization and Laplace transform were adopted to balance contrast enhancement and details *** weighting factors of image foreground and background were determined by the amount of their respective *** proposed method was conducted to images acquired from CVG⁃UGR and US⁃SIPI image databases and then compared with other methods such as clipping histogram spikes,histogram addition,and non⁃linear transformation to verify its *** show that the proposed algorithm can effectively enhance the contrast without introducing distortions,and preserve the mean brightness and details well at the same time.

关键词： contrast enhancement weighted processing histogram equalization Laplace transform

在线全文

学校读者我要写书评

暂无评论

模拟退火算法用于蒸汽吞吐井流入动态研究

石油化工应用 2024年第7期43卷 36-39,59页

作者：辛文宾王中元宫宇宁蒋海岩王哲田蕃尚晨浩西安石油大学石油工程学院陕西西安710065 中国石油辽河油田分公司勘探开发研究院辽宁盘锦124010 中国石化西北油田分公司新疆乌鲁木齐830011

随着油气田开发技术的发展,利用复杂结构井、体积压裂、多元及复杂热力法开采石油时,渗流过程越来越复杂,油井流入动态难以通过统一方程得到。本文提出利用非数值算法的模拟退火算法进行油井流入动态计算,以蒸汽吞吐井为实例,首先分析... 详细信息

随着油气田开发技术的发展,利用复杂结构井、体积压裂、多元及复杂热力法开采石油时,渗流过程越来越复杂,油井流入动态难以通过统一方程得到。本文提出利用非数值算法的模拟退火算法进行油井流入动态计算,以蒸汽吞吐井为实例,首先分析合理的工作制度,然后把模拟退火算法预测的产量结果与利用数值模拟所得的产量结果进行比较。结果表明,两种方法对比误差非常小,模拟退火算法不需要将单相流和多相流分开讨论,且无任何假设条件,适用范围广,利用该算法研究油井流入动态非常可行。

关键词：油井流入动态蒸汽吞吐数值模拟模拟退火油井产量