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Effect of Sodium Ferulate on Myocardial Ischemia Fibrosis Induced by Isoproterenol

Chemical Research in Chinese Universities 2009年第5期25卷 699-704页

作者： GAO Hai-cheng sun Bo yu Xiao-yan GAO Hai-mei SHI yan MIAO Chun-sheng LI Xiang-jun LUO Ping ZOU Ying-gang WEI Hai-feng ZHAO Juan REN Li-qun school of Pharmacy Jilin University Changchun 130021 P. R. China The Second Clinical Hospital of Jilin university Changchun 130041 P. R. China

We examined whether the powerful sodium ferulate（SF） could improve myocardial ischemia fibrosis degree and gain the information of myocardial energy metabolism via experimental model of myocardial ischemia fibrosis. The model of myocardial ischemia fibrosis was made for the wistar rats induced with 15 mg/kg isoproterenol（Iso） subcutaneous injection. In experiment l, Iso effective model drug of myocardial ischemia fibrosis at present was administrated to the rats with myocardial ischemia fibrosis and 2, 4, 6, 12, 24, 48 and 72 h, 7 and 21 d later, the changes of adenosine content in rat myocardial tissue and hydroxyproline in blood serum were compared. In experiment 2, SF was administrated to the rats with myocardial ischemia fibrosis and 21 d later, the effect of SF on benazepril as reference drug curing myocardial ischemia fibrosis was evaluated by measuring the changes of adenosine in rat myocardial tissue and hydroxyproline content in blood serum. In the model group, there was a remarkable increase in hydroxyproline content and a decrease in adenosine content of myocardial tissue in experiment 1; there was a remarkable decrease in hydroxyproline in blood serum and a increase in adenosine content in myocardial tissue, which were recovered gradually to control in experiment 2（P〈0.05）. The results of experiment 1 show that with the increasing of pathological change degree, the rat adenosine content reduced gradually and arrived at the lowest value three weeks later（P〈0.05）; the hydroxyproline content was obviously higher compared with that of control group（P〈0.05）. The results of experiment 2 show that rat adenosine content in myocardial tissue and hydroxyproline content in blood serum were recovered gradually to normal level after injection SF. The effect of SF against myocardial ischemia fibrosis in preventive group is better than that of improving the myocardial ischemia fibrosis drug. Meanwhile, hinting HPLC is a good method to measure the adenosine content.

关键词： Energy metabolism Hydroxyproline Myocardial fibrosis HPLC

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Updatable Identity-Based Hash Proof System Based on Lattices and Its Application to Leakage-Resilient Public-Key Encryption Schemes

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Journal of computer science & Technology 2018年第6期33卷 1243-1260页

作者： Qi-Qi Lai Bo yang Yong yu Zhe Xia yan-Wei zhou yuan Chen school of computer science Shaanxi Normal University Xi'an 710119 China State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences Beijing 100093 China school of computer science and Technology Wuhan University of Technology Wuhan 430070 China State Key Laboratory of Integrated Services Networks Xidian University Xi'an 710071 China

Identity-based hash proof system is a basic and important primitive. Ittographic schemes and protocols that are secure against key-leakage attacks. In thisupdatable identity-based hash proof system, in which the related master secret keyis widely utilized to construct cryp-paper, we introduce the concept ofand the identity secret key can beupdated securely. Then, we instantiate this primitive based on lattices in the standard model. Moreover, we introduce anapplication of this new primitive by giving a generic construction of leakage-resilient public-key encryption schemes withanonymity. This construction can be considered as the integration of the bounded-retrieval model and the continual leakagemodel. Compared with the existing leakage-resilient schemes, our construction not only is more efficient but also can resistmuch more key leakage.

关键词： public-key encryption identity-based hash proof system lattice updatable leakage-resilience

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基于极限编程的统一过程探讨

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西南师范大学学报（自然科学版） 2004年第2期29卷 209-212页

作者：钟琪何俊梅张为群西南师范大学计算机与信息科学学院重庆400715

对统一过程 (UnifiedProcess,UP)、极限编程 (eXtremeProgramming ,XP)进行了简要分析 ,结合这两者在软件开发中所表现出来的优点 ,提出了一种使用XP的自底向上方法对UP的自顶向下方法进行改进的方案 .

关键词：极限编程统一过程软件开发自底向上方法软件过程

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Effects of nutritional status on saccharin intakes and preference

Effects of nutritional status on saccharin intakes and prefe...

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中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Ke CHEN~1,Jian-qun yan~(1,2,*),Yi SUO~1,Jin-Rong LI~1,Xiao-Lin ZHAO~1,Bo LV~1 1 Department of Physiology and Pathophysiology,Xi''an Jiaotong university school of Medicine,Xi''an,china 2 Key Laboratory of Environment and Genes Related to Diseases,Ministry of Education,Xi''an Jiaotong university school of Medicine,Xi''an,710061,china

＜正＞Objective It is commonly accepted that a close linkage exists between sweet taste perception and nutritional *** previous studies showed that there were significant differences in the intakes and preference ratios of richcaloric sucrose among the rats upon a change of nutritional *** saccharin is a non-caloric sweetener,the effect of metabolic state on the preference of saccharin is *** present study is to assess how nutritional status alters the preference ratios of palatable and no-caloric solutions *** We measured saccharin intakes and preference ratios using two-bottle preference test,compared the changes in body weight,plasma glucose,insulin and leptin levels in two different animal models of altered nutritional status,namely,the high-fat diet induced obese rats and the chronically restricted-diet ***（1） The preference ratio of 0.005M saccharin decreased markedly in obese rats （n=12,P=0.031） and the preference ratio of 0.04M saccharin elevated significantly in chronically restricted diet rats（n=12, P=0.010） compared with those of the normal diet rats.（2） The plasma leptin（7.45±0.30 vs.6.18±0.46,P=0.028） and glucose （7.26±0.87 vs.5.65±0.17,P=0.038） levels in obese rats were significantly elevated;the serum insulin（20.99±1.41 vs.33.22±1.94,P=0.000） and glucose level（4.13±0.13 vs.5.65±0.17,P=0.048） decreased markedly in restricted diet rats compared with control *** Nutritional status alters the perception of saccharin and the change of serum leptin may be involved in. sweet preference;dietary-induced obesity;saccharin;restricted diet;leptin

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Adjoining Batch Markov Arrival Processes of a Markov Chain

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Acta Mathematicae Applicatae Sinica 2018年第1期34卷 1-10页

作者： Xiao-yun MO Xu-yan XIANG Xiang-qun yanG College of mathematics and Statistics Hunan University of Finance and Economics Changsha 410205 China College of mathematics and Computational science Hunan University of Arts and Science Changde 415000 China Key Laboratory of High performance Computing and Stochastic Information Processing Ministry of Education of China College of Mathematics and Computer Science Hunan Normal University Changsha 410081 China Hunan Province Cooperative Innovation Center for the Construction and Development of Dongting Lake Ecological Economic Zone Changde 415000 China

A batch Markov arrival process（BMAP） X^＊=（N, J） is a 2-dimensional Markov process with two components, one is the counting process N and the other one is the phase process J. It is proved that the phase process is a time-homogeneous Markov chain with a finite state-space, or for short, Markov chain. In this paper,a new and inverse problem is proposed firstly： given a Markov chain J, can we deploy a process N such that the 2-dimensional process X^＊=（N, J） is a BMAP？ The process X^＊=（N, J） is said to be an adjoining BMAP for the Markov chain J. For a given Markov chain the adjoining processes exist and they are not unique. Two kinds of adjoining BMAPs have been constructed. One is the BMAPs with fixed constant batches, the other one is the BMAPs with independent and identically distributed（i.i.d） random batches. The method we used in this paper is not the usual matrix-analytic method of studying BMAP, it is a path-analytic method. We constructed directly sample paths of adjoining BMAPs. The expressions of characteristic（D_k, k = 0, 1, 2· · ·）and transition probabilities of the adjoining BMAP are obtained by the density matrix Q of the given Markov chain J. Moreover, we obtained two frontal Theorems. We present these expressions in the first time.

关键词： Markov chain batch Markov arrival process (BMAP) adjoining BMAP fixed constant batch independent identically distributed (i.i.d) random batch

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新高中数学课程标准与原教学大纲的比较研究

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数学教育学报 2004年第1期13卷 63-66页

作者：孙名符谢海燕西北师范大学数学与信息科学学院甘肃兰州730070

新的《普通高中数学课程标准(实验)》与原《全日制普通高中数学教学大纲(试验修订版)》相比,有以下特点:对数学本质有了新的认识,这种新认识体现了一种动态的模式论的现代数学观;课程目标突出体现了学生发展为中心的思想;课程内容在为... 详细信息

新的《普通高中数学课程标准(实验)》与原《全日制普通高中数学教学大纲(试验修订版)》相比,有以下特点:对数学本质有了新的认识,这种新认识体现了一种动态的模式论的现代数学观;课程目标突出体现了学生发展为中心的思想;课程内容在为课程目标服务的原则下增强了选择性;课程评价进一步丰富和完善了大纲多元化的理念.

关键词：高中数学课程标准教学大纲动态模式论数学观课程功能观课程目标

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computer-aided diagnosis of Alzheimer’s disease based on structural magnetic resonance imaging

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Chinese Medical Journal 2024年第12期137卷 1483-1485页

作者： Yihang Huang Keyi Shan yuzi yan Wan Li school of computer science and Engineering Beijing Technology and Business UniversityBeijing 100048China

To the Editor:Alzheimer’s disease(AD)is an irreversible chronic neurodegenerative *** initially affects short-term memory,thinking,and *** then severely disrupts the normal lives of patients and their families and may eventually lead to *** cognitive impairment(MCI)is considered an early stage of *** studies have shown that nearly 20%of patients with MCI are at a risk of developing AD within the next four years.[1]Although there is no impressive way to stop the further development of MCI,only a series of procedures can slow ***,timely and accurate intervention is essential to effectively slow the disease progression.

关键词： diagnosis Alzheimer eventually

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形式化的软件测试模型研究

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计算机科学 2004年第11期31卷 169-173页

作者：赖祥伟张为群邱玉辉周彦晖西南师范大学计算机与信息科学学院重庆400715

传统方法中基于软件测试工程师经验的测试用例构造技术使得软件测试的质量很难得到保证。本文提出一种基于形式化方法的软件测试模型。该模型使用形式化描述语言RSL对软件设计进行描述,并在此基础上提出了自动生成软件测试各个阶段所需... 详细信息

传统方法中基于软件测试工程师经验的测试用例构造技术使得软件测试的质量很难得到保证。本文提出一种基于形式化方法的软件测试模型。该模型使用形式化描述语言RSL对软件设计进行描述,并在此基础上提出了自动生成软件测试各个阶段所需测试用例的方法框架以及相关实验结论。

关键词：软件测试模型测试用例形式化方法描述语言 RSL 自动生成软件设计实验结论阶段传统方法

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质子交换膜燃料电池风机控制技术研究

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计算机工程与应用 2004年第36期40卷 223-225页

作者：毋茂盛张玉珊余达太晏蔚光河南师范大学计算机系河南新乡453007 北京科技大学信息学院北京100083

该文首先研究了质子交换膜燃料电池(PEMFC)风机的性能,分析了PEMFC的工作温度对其性能的影响,并给出了控制PEMFC风机的数学模型。然后,对高电压、大电流运算放大器OPA548进行了详细的介绍,设计了用OPA548控制PEMFC风机工作电压的硬件电... 详细信息

该文首先研究了质子交换膜燃料电池(PEMFC)风机的性能,分析了PEMFC的工作温度对其性能的影响,并给出了控制PEMFC风机的数学模型。然后,对高电压、大电流运算放大器OPA548进行了详细的介绍,设计了用OPA548控制PEMFC风机工作电压的硬件电路,最后,对使用OPA548时应注意的事项进行了讨论。

关键词：质子交换膜燃料电池温度风机控制运算放大器

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A Novel Bidirectional Interaction Model and Electric Energy Measuring Scheme of EVs for V2G with Distorted Power Loads

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computer Modeling in Engineering & sciences 2022年第3期130卷 1789-1806页

作者： Jiarui Cui Qing Li Bin Cao Xiangquan Li qun yan school of Automation and Electrical Engineering University of Science and Technology BeijingBeijing100083China Guiyang Aluminum Magnesium Design and Research Institute Co. Ltd.Guiyang550081China chinalco Intelligent Technology Development Co. Ltd.Hangzhou311199China

With the increasing demand for petroleum resources and environmental issues,new energy electric vehicles are increasingly being ***,the large number of electric vehicles connected to the grid has brought new challenges to the operation of the ***,A novel bidirectional interaction model is established based on modulation theory with nonlinear ***,the electric energy measuring scheme of EVs for V2G is derived under the conditions of distorted power *** scheme is composed of fundamental electric energy,fundamental-distorted electric energy,distorted-fundamental electric energy and distorted electric *** the characteristics of each electric energy are ***,the correctness of the model and energy measurement method is verified by three simulation cases:the impact signals,the fluctuating signals,and the harmonic signals.

关键词： Electric vehicles V2G energy metering bidirectional interaction model electric energy measuring scheme

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