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“Slope-adsorption & plateau-pore filling” mechanism unlocking the potential of hard carbon anodes for “fast-charging & large-sized”batteries

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Science China Materials 2025年第1期 309-311页

作者： Tian liang Xiaoming Zhu Hubei Key Laboratory of Radiation Chemistry and Functional Materials School of Nuclear Technology and Chemistry & Biology Hubei University of Science and Technology

To date, there has been no report on fast-charging and Ahlevel sodium-ion batteries (SIBs) by utilizing thick hard carbon anodes that demonstrate prolonged cycling life and high areal capacity at high rates. Further, the relationship among the complex structure of hard carbon, storage mechanism, and fastcharging performance in alkali-metal ion batteries has been a subject of ongoing debate [1,2].

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杏仁多肽的降血糖活性研究

内蒙古农业大学学报（自然科学版） 2010年第2期31卷 204-208页

作者：刘雪峰李磊闫文亮乔宵龙李婧王勋任文明内蒙古农业大学食品科学与工程学院呼和浩特010018 内蒙古农业大学理学院呼和浩特010018

目的:研究杏仁多肽对糖尿病大鼠辅助降血糖活性。方法:40只成年雄性Wistar大鼠随机分为5组,其中两组未注射STZ,分别饲喂正常饲料(正常对照组)和杏仁多肽(正常口服组),经STZ注射造模的其他3组,分别饲喂正常饲料(糖尿病对照组),每天灌胃10... 详细信息

目的:研究杏仁多肽对糖尿病大鼠辅助降血糖活性。方法:40只成年雄性Wistar大鼠随机分为5组,其中两组未注射STZ,分别饲喂正常饲料(正常对照组)和杏仁多肽(正常口服组),经STZ注射造模的其他3组,分别饲喂正常饲料(糖尿病对照组),每天灌胃10g/***杏仁多肽(口服高剂量组),每天灌胃5g/***杏仁多肽(口服低剂量组),测定5d、10d、15d、20d、25d、30d、停药12d空腹血糖,血清中总胆固醇、甘油三酯及胰岛素。结果:与对照组相比,口服高剂量组和口服低剂量组在20d时均能显著降低糖尿病大鼠的血糖水平(p<0.05),25d时使血清中总胆固醇及甘油三酯水平显著降低,血清中胰岛素显著升高(p<0.05)。结论:杏仁多肽能有效调节糖尿病大鼠的血糖及血脂生化指标,对高脂糖尿病具有辅助治疗效果。

关键词：杏仁多肽降血糖

The dopaminergic system and Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang Yuan liang Yixue Gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

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新疆地区规模化奶牛场牛支原体流行病学调查

中国动物传染病学报 2013年第5期21卷 68-71页

作者：李岩姚永进范伟兴剡文亮石刚剡根强新疆生产建设兵团畜牧兽医工作总站乌鲁木齐830063 石河子大学动物科技学院石河子832003 中国动物卫生与流行病学中心青岛266032

为了调查新疆地区规模化奶牛场牛支原体的感染情况,采用牛支原体间接ELISA和特异性PCR检测牛血清中的牛支原体抗体及病料中牛支原体核酸,共检测9个地区15个规模化奶牛场437份血清,肺脏、关节液及鼻腔黏液44份。结果显示,血清抗体阳性率... 详细信息

为了调查新疆地区规模化奶牛场牛支原体的感染情况,采用牛支原体间接ELISA和特异性PCR检测牛血清中的牛支原体抗体及病料中牛支原体核酸,共检测9个地区15个规模化奶牛场437份血清,肺脏、关节液及鼻腔黏液44份。结果显示,血清抗体阳性率为76.43%(334/437),其中脐带血抗体阳性率为40.00%(4/10);病料阳性率为40.91%(18/44)。检测结果表明,新疆地区大部分奶牛场存在牛支原体感染,部分奶牛场发生牛支原体肺炎及关节炎病例,并存在垂直传播的风险。牛支原体感染可能成为危害新疆规模化奶牛场犊牛健康的主要疫病之一。

关键词：奶牛牛支原体 PCR 感染间接ELISA

基于弹丸膛内运动参数和压力测试的火炮膛内燃气温度估算方法

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火工品 2025年第1期 51-54页

作者：赵煜华闫光虎肖霞严文荣梁磊西安近代化学研究所陕西西安710065

为了解决火炮膛内测试环境恶劣而导致发射药燃气温度测试难度大的问题,基于微波干涉仪、压力测试系统,结合发射药配方性能计算理论、装药内弹道性能计算模型等理论,建立了一种基于实测参数的火炮膛内燃气温度估算方法,并开展了试验研究... 详细信息

为了解决火炮膛内测试环境恶劣而导致发射药燃气温度测试难度大的问题,基于微波干涉仪、压力测试系统,结合发射药配方性能计算理论、装药内弹道性能计算模型等理论,建立了一种基于实测参数的火炮膛内燃气温度估算方法,并开展了试验研究。结果表明:火炮膛内燃气温度的最高值约为2631.8 K,随着弹丸运动迅速降低,弹丸出炮口时膛内燃气温度降低到约1858.4 K;建立的火炮膛内发射药燃气温度估算方法可以有效地获得火炮整个内弹道过程中火药燃气温度随时间的变化规律,为低烧蚀发射药及装药的研制提供了一种新的研究手段。

关键词：发射药膛内燃气温度估算方法微波干涉仪

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粪菌移植治疗溃疡性结肠炎的临床观察及护理

中国临床护理 2016年第6期8卷 486-488页

作者：文艳梁健李芳兰肖艳梅广东省深圳市光明新区人民医院ICU 广东深圳518106

目的观察粪菌移植治疗溃疡性结肠炎的治疗效果。方法选取2012年12月-2015年2月进行粪菌移植治疗的溃疡性结肠炎患者6例,给予健康宣教、心理护理、饮食护理和延续护理等护理干预措施。比较粪菌移植治疗前后Mayo评分、患者的满意度和治疗... 详细信息

目的观察粪菌移植治疗溃疡性结肠炎的治疗效果。方法选取2012年12月-2015年2月进行粪菌移植治疗的溃疡性结肠炎患者6例,给予健康宣教、心理护理、饮食护理和延续护理等护理干预措施。比较粪菌移植治疗前后Mayo评分、患者的满意度和治疗后不良反应发生情况。结果粪菌移植治疗后Mayo评分由治疗前的(4.60±1.53)分降至(1.33±0.42)分,差异具有统计学意义(t=8.553,P=0.001)。6例患者均对粪菌移植治疗有应答,其中5例患者达到临床缓解。6例患者中,很满意的4例,基本满意1例,一般的1例,患者的总体满意率为83.33%。6例患者均顺利完成粪菌移植治疗,无严重不良反应发生。结论溃疡性结肠炎患者采用粪菌移植治疗并给予细致、周到的护理,治疗效果好,严重不良反应发生率低,患者的满意度高。

关键词：粪菌移植溃疡性结肠炎治疗效果护理

Joint Probabilistic Scheduling and Resource Allocation for Wireless Networked Control Systems

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 258-260页

作者： Meng Zheng Lei Zhang Wei liang IEEE the State Key Laboratory of Robotics and the Key Laboratory of Networked Control Systems Shenyang Institute of Automation Chinese Academy of Sciences the University of Chinese Academy of Sciences

Dear Editor,This letter presents a joint probabilistic scheduling and resource allocation method(PSRA) for 5G-based wireless networked control systems(WNCSs). As a control-aware optimization method, PSRA minimizes the linear quadratic Gaussian(LQG) control cost of WNCSs by optimizing the activation probability of subsystems, the number of uplink repetitions, and the durations of uplink and downlink phases. Simulation results show that PSRA achieves smaller LQG control costs than existing works.

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Direct numerical simulation of compressible turbulent flows

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Acta Mechanica Sinica 2010年第6期26卷 795-806页

作者： Xin-liang Li De-Xun Fu yan-wen Ma Xian liang LHD Institute of MechanicsChinese Academy of Sciences 100190 BeijingChina LNM Institute of MechanicsChinese Academy of Sciences 100190 BeijingChina

This paper reviews the authors＇ recent studies on compressible turbulence by using direct numerical simulation （DNS）,including DNS of isotropic（decaying） turbulence, turbulent mixing-layer,turbulent boundary-layer and shock/boundary-layer *** statistics, compressibility effects,turbulent kinetic energy budget and coherent structures are studied based on the DNS *** mechanism of sound source in turbulent flows is also analyzed. It shows that DNS is a powerful tool for the mechanistic study of compressible turbulence.

关键词： Direct numerical simulation Compressible turbulence Coherent structures Turbulent boundary-layer flow

Epigenetic regulation of the inflammatory response in stroke

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Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi liang Fei yang Zixiao Li Qian Li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment