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A Distortion Self-Calibration Method for Binocular High Dynamic Light Adjusting and Imaging System Based on Digital Micromirror Device

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IEEE/CAA Journal of Automatica Sinica 2024年第9期11卷 2036-2038页

作者： Pei wu Yanjie Wang Honghai sun Zhuoman wen University of Chinese Academy of Sciences Beijing 100049and NIO Inc.Shanghai 200000China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China

Dear Editor,In order to realize the pixel level light adjusting control of the binocular high dynamic light adjusting and imaging system, this letter proposed a novel self-calibration method. By analyzing the optical design of the system, the causes of the distortion are given and a distortion model is established. Then, a quick and accurate self-calibration method is designed. The experiments indicate that the method can calibrate the two image sensors of the system at the same time,the average pixel deviation of the calibrated system is less than 0.5pixels and the maximum deviation is less than 1 pixel.

关键词： Dynamic system deviation

The Functional Redundancy of Neddylation E2s and E3s in Modulating the Fitness of Regulatory T Cells

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Research 2024年第2期2023卷 373-387页

作者： Di wu Yi sun Cancer Institute(Key Laboratory of Cancer Prevention and Intervention China National Ministry of Education)of the Second Affiliated Hospital and Institute of Translational MedicineZhejiang University School of MedicineHangzhou 310029China Cancer Center of Zhejiang University Hangzhou 310029China Zhejang Provincial Clinical Research Center for Cancer Zhejang ProvinceChina Key Laboratory of Molecular Biology in Medical Sciences Zhejang ProvinceChina Research Center for Life Science and Human Health Binjiang Institute of Zhejiang UniversityHangzhou 310053China

Neddylation is necessary for activation of Cullin-RING ligases(CRLs),which degrade various immune regulatory *** recent study showed that while depletion of neddylation E2-E3 pair Ube2f-Sag in regulatory T(T_(reg))cells had no obvious phenotype,the same depletion of either Ube2m or Rbx1 caused inflammation disorders with different *** these E2s or E3s compensate each other in functional regulations of T_(reg)cells is,however,previously *** this report,we generated Foxp3^(Cre);Ube2m^(fl/fl);Ube2f^(fl/fl)or Foxp3^(Cre);Rbx1^(fl/fl);Sag^(fl/fl)double-null mice by simultaneous deletion of both neddylation E2s or E3s in T_(reg)cells,***,Ube2m&Ube2f double-null mice developed much severe autoimmune phenotypes than did Ube2m-null mice,indicating that Ube2m markedly compensates Ube2f in T_(reg)*** minor worsened autoimmune phenotypes seen at the very early stage in Rbx1&Sag double-null than Rbx1-null mice is likely due to already severe phenotypes of the later,indicating a minor compensation of Rbx1 for *** RNA profiling-based analyses revealed that up-and down-regulations of few signaling pathways in T_(reg)cells are associated with the severity of autoimmune ***,severer inflammation phenotypes seen in mice with double E3-null than with double E2-null T_(reg)cells indicate a neddylation-independent mechanism of 2 E3s,also known to serve as the RING component of CRLs in regulation of T_(reg)cell fitness.

关键词： Foxp3 inflammation markedly

Rational surface charge engineering of haloalkane dehalogenase for boosting the enzymatic performance in organic solvent solutions

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Chinese Journal of Chemical Engineering 2024年第1期65卷 276-285页

作者： Yin wu Yan sun Department of Biochemical Engineering School of Chemical Engineering and Technology and Key Laboratory of Systems Bioengineering and Frontiers Science Center for Synthetic Biology(Ministry of Education)Tianjin UniversityTianjin 300350China

Biocatalysis in organic solvents(OSs)has numerous important applications,but native enzymes in OSs often exhibit limited catalytic ***,we proposed a computation-aided surface charge engineering strategy to improve the catalytic performance of haloalkane dehalogenase DhaA in OSs based on the energetic analysis of substrate binding to the DhaA *** variants with enhanced OS resistance were obtained by replacing negative charged residues on the surface with positive charged residue(Arg).Particularly,a four-substitution variant E16R/E93R/E121R/E257R exhibited the best catalytic performance(five-fold improvement in OS resistance and seven-fold half-life increase in 40%(vol)dimethylsulfoxide).As a result,the overall catalytic performance of the variant could be at least 26 times higher than the wild-type *** spectroscopy and molecular dynamics simulation studies revealed that the residue substitution mainly enhanced OS resistance from four aspects:(a)improved the overall structural stability,(b)increased the hydrophobicity of the local microenvironment around the catalytic triad,(c)enriched the hydrophobic substrate around the enzyme molecule,and(d)lowered the contact frequency between OS molecules and the catalytic *** findings validate that computationaided surface charge engineering is an effective and ingenious rational strategy for tailoring enzyme performance in OSs.

关键词： Surface charge engineering Organic solvent resistance Molecular dynamics simulation Haloalkane dehalogenase

Characteristics of microscopic pore heterogeneity and development model of wufeng‒Longmaxi Shales in the Pengshui area of south-east Chongqing

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Frontiers of Earth Science 2024年第1期18卷 188-203页

作者： Lu sun Zhigang wen Guisong HE Peixian ZHANG Chenjun wu Liwen ZHANG Yingyang XI Bo LI College of Resources and Environment Yangtze UniversityWuhan 430100China Research Institute of Exploration and Development Sinopec East China CompanyNanjing 210011China

Normal-pressure shale gas reservoirs are widely distributed in south-eastern Chongqing and show good potential for resource *** paper reports the organic matter(OM),physical,and pore characteristics,mineral composition,and gas content of representative shale samples from the Upper Ordovician wufeng Formation and Member 1 of the Lower Silurian Longmaxi Formation(Long 1 Member).Microscopic pores within different shale layers of the Long 1 Member were classified,quantitatively evaluated,and their development mechanisms were systematically *** found that OM characteristics,mineral composition,and pore type were the main factors affecting the enrichment and preservation of shale *** characteristics of the Long 1 Member are mainly controlled by changes in the sedimentary *** are evident differences in total organic carbon content and mineral composition vertically,leading to a variable distribution of pores across different *** matter abundance controls the degree of OM pore development,while clay minerals abundance control the development of clay mineral-related *** organic carbon content generally controls the porosity of the Long 1 Member,but clay minerals also play a role in OM-poor *** connectivity and permeability are influenced by the development of pores associated with brittle *** propose a microscopic pore development model for the different *** geochemical data and this pore development model,layers 1‒4 are considered to be excellent shale gas preservation and enrichment *** preservation conditions in layers 5‒7 result in high levels of shale gas *** 8‒9 possess a better sealing condition compared with layers 5‒7 and are conducive to the enrichment and preservation of shale gas,and can thus be used as future potential target *** research provides a theoretical basis for exploring and evaluating shale gas potential in the studied region or other co

关键词： shale gas pore characteristics Longmaxi Formation reservoir model

On the global smooth solutions of 3D incompressible Hall-MHD equations

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Applied Mathematics(A Journal of Chinese Universities) 2024年第2期39卷 319-327页

作者： YUE Gao-cheng sun wen-da School of Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 211106China

The present paper is devoted to the well-posedness issue for the 3D incompressible Hall-MHD system obtained from kinetic models. Our analysis strongly relies on the use of the Fourier analysis. We establish the global existence of smooth solutions for a class of large initial data, this result implies the initial velocity and magnetic field can be arbitrarily large.

关键词： 3D Hall-MHD well-posedness Fourier analysis

Weakly Approximate Diagonalization of Homomorphisms into Finite von Neumann Algebras

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2187-2194页

作者： wen Hua QIAN Jun Hao SHEN wen Ming wu School of Mathematical Sciences Chongqing Normal UniversityChongqing 401331P.R.China Department of Mathematics and Statistics University of New HampshireDurhamNH 03824USA

Let A be a unital C^(∗)-algebra and B a unital C^(∗)-algebra with a faithful traceτ.Let n be a positive *** give the definition of weakly approximate diagonalization(with respect toτ)of a unital homomorphismφ:A→Mn(B).We give an equivalent characterization of McDuff Ⅱ_(1) *** show that,if A is a unital nuclear C^(∗)-algebra and B is a type Ⅱ_(1) factor with faithful traceτ,then every unital^(∗)-homomorphism φ:A→M_(n)(B)is weakly approximately *** B is a unital simple infinite dimensional separable nuclear C^(∗)-algebra,then any finitely many elements in Mn(B)can be simultaneously weakly approximately diagonalized while the elements in the diagonals can be required to be the same.

关键词： Weakly approximately diagonalizable McDuff factors nuclear hyperfinite

Impact of open hepatectomy on postoperative bile leakage in patients with biliary tract cancer

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 67-75页

作者： Gang wu wen-Ying Li Yu-Xing Gong Feng Lin Chen sun General Surgery Department The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150000Heilongjiang ProvinceChina

BACKGROUND Bile leakage is a common and serious complication of open hepatectomy for the treatment of biliary tract *** To evaluate the incidence,risk factors,and management of bile leakage after open hepatectomy in patients with biliary tract *** We retrospectively analyzed 120 patients who underwent open hepatectomy for biliary tract cancer from February 2018 to February *** leak was defined as bile drainage from the surgical site or drain or the presence of a biloma on *** incidence,severity,timing,location,and treatment of the bile leaks were *** risk factors for bile leakage were analyzed using univariate and multivariate logistic regression *** The incidence of bile leak was 16.7%(20/120),and most cases were grade A(75%,15/20)according to the International Study Group of Liver Surgery *** median time of onset was 5 d(range,1-14 d),and the median duration was 7 d(range,2-28 d).The most common location of bile leakage was the cut surface of the liver(70%,14/20),followed by the anastomosis site(25%,5/20)and the cystic duct stump(5%,1/20).Most bile leaks were treated conservatively with drainage,antibiotics,and nutritional support(85%,17/20),whereas some required endoscopic retrograde cholangiopancreatography with stenting(10%,2/20)or percutaneous transhepatic cholangiography with drainage(5%,1/20).Risk factors for bile leakage include male sex,hepatocellular carcinoma,major hepatectomy,blood loss,and blood *** Bile leakage is a frequent complication of open hepatectomy for biliary tract ***,most cases are mild and can be conservatively *** sex,hepatocellular carcinoma,major hepatectomy,blood loss,and blood transfusion were associated with an increased risk of bile leak.

关键词： Open hepatectomy Bile leak Biliary tract cancer Risk factors Management Complication

Enhanced direct gaseous CO_(2) fixation into higher bio-succinic acid production and selectivity

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Journal of Environmental Sciences 2024年第9期143卷 164-175页

作者： Ziyi Yang Wanling wu Qing Zhao Irini Angelidaki Samuel Gyebi Arhin Dongliang Hua Yuxiao Zhao Hangyu sun Guangqing Liu wen Wang Biomass Energy and Environmental Engineering Research Center Beijing University of Chemical TechnologyBeijing 100029China College of Chemical Engineering Beijing University of Chemical TechnologyBeijing 100029China Department of Chemical and Biochemical Environmental Engineering Technical University of DenmarkDK-2800Kgs LyngbyDenmark Energy Research Institute Qilu University of Technology(Shandong Academy of Sciences)Shandong Provincial Key Laboratory of Biomass Gasification TechnologyJinan 250014China

Utilizing CO_(2)for bio-succinic acid production is an attractive approach to achieve carbon capture and recycling(CCR)with simultaneous production of a useful platform *** succinogenes and Basfia succiniciproducens were selected and investigated as microbial ***,the type and concentration of inorganic carbon concentration and glucose concentration were evaluated.6 g C/L MgCO_(3)and 24 g C/L glucose were found to be the optimal basic operational conditions,with succinic acid production and carbon yield of over 30 g/L and over 40%,***,for maximum gaseous CO_(2)fixation,carbonate was replaced with CO_(2)at different ***“less carbonate more CO_(2)”condition of the inorganic carbon source was set as carbonate:CO_(2)=1:9(based on the mass of carbon).This condition presented the highest availability of CO_(2)by well-balanced chemical reaction equilibrium and phase equilibrium,showing the best performance with regarding CO_(2)fixation(about 15 mg C/(L·hr)),with suppressed lactic acid *** to key enzymes analysis,the ratio of phosphoenolpyruvate carboxykinase to lactic dehydrogenase was enhanced at high ratios of gaseous CO_(2),which could promote glucose conversion through the succinic acid *** further increase gaseous CO_(2)fixation and succinic acid production and selectivity,stepwise CO_(2)addition was evaluated.50%-65%increase in inorganic carbon utilization was obtained coupled with 20%-30%increase in succinic acid *** was due to the promotion of the succinic acid branch of the glucose metabolism,while suppressing the pyruvate branch,along with the inhibition on the conversion from glucose to lactic acid.

关键词： Succinic acid CO_(2) fixation Actinobacillus succinogenes Basfia succiniciproducens Lactic acid

Feeding prehistoric coastal community:A study of marine faunal remains at the Jingtoushan site

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Science China Earth Sciences 2024年第5期67卷 1574-1590页

作者： Endong wu Guoping sun Ying ZHANG School of Culture History and LanguageAustralian National UniversityCanberra 2600Australia Zhejiang Provincial Institute of Cultural Relics and Archaeology Hangzhou 310012China National Centre for Archaeology Beijing 100013China

This article examines the abundant marine mollusc,and fish remains at the Jingtoushan shell midden(8,300 to7,800 cal a BP)in Zhejiang Province,China,to investigate the fishing economy,community development,the palaeoenvironment,and their interactions among the prehistoric populations in the lower Yangtze River Basin and southeastern coastal *** also attempts to explore the prosperity and decline of coastal settlements in China during the Neolithic Age and the potential reasons for their rise and fall,*** on the ecological and biological principles of marine animals,standard zooarchaeological methods and radiocarbon dating analysis are used for sampling,identification,measurement,and *** show that at least 11 mollusc taxa and 14 fish taxa can be identified from the Jingtoushan faunal *** ancient Jingtoushan residents possibly lived in a settlement close to the coast and engaged in inshore and offshore fishing,hunting,and gathering as their primary subsistence strategies,with low-level rice cultivation as a supplementary means of ***,the changes in the coastal environment could be one of the reasons why the Jingtoushan residents abandoned their *** research contributes to Chinese Neolithic archaeology with new evidence of the exploitation of marine resources around 8000 a BP in the eastern coastal areas and the relationship between Neolithic community development and environmental changes.

关键词： Neolithic Age Marine faunal remains Fishing economy Palaeoenvironment Community development