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High expression of CD11c indicates favorable prognosis in patients with gastric cancer

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World Journal of Gastroenterology 2015年第31期21卷 9403-9412页

作者： Yuan Wang Bin Xu wen-wei hu Lu-Jun Chen Chang-Ping Wu Bin-Feng Lu Yue-Ping Shen Jing-Ting Jiang Department of Tumor Biological Treatment the Third Affiliated Hospital of Soochow University School of Clinical Medicine North China University of Science and Technology Department of Immunology University of Pittsburgh Jiangsu Key Laboratory of Preventive and Trans-lational Medicine for Geriatric Diseases School of Public HealthSoochow University

AIM: To determine the relationship between CD11 c expression level and prognosis in patients with gastric cancer(GC).METHODS: This retrospective survival study was performed from July 31,2008 to June 30,2014. Our study inclusion criteria included all the patients with GC who underwent surgical resection between January 1998 and December 2009 in the Third Affiliated Hospital of Soochow University. CD11 c expression levels in 140 patients with GC at different UICC stages were evaluated using immunohistochemistry,and GC tissues from 16 cases were further verified by q RTPCR. The χ2 test was used to compare the patientand disease-related factors between the low CD11 c expression group and the high expression group. Univariate probabilities of overall survival(OS) and disease-free survival(DFS) were assessed using the Kaplan-Meier method. The log rank test was used to compare survival curves. Different multivariate COX models were used to estimate the association between CD11 c expression and both death and recurrence riskin GC ***: The average CD11 c expression level was 5.1 ± 1.8/high power field(HPF) in 10 gastritis samples,4.5 ± 2.3/HPF in 10 gastric polyp samples and 9.7 ± 6.3/HPF in 140 gastric cancer samples,respectively. The CD11 c expression level was significantly decreased from UICC stage Ⅰ to stage Ⅳ(stage Ⅰ: 16.0 ± 7.4,stage Ⅱ: 10.4 ± 5.5,stage Ⅲ: 9.4 ± 6.1,stage Ⅳ: 5.3 ± 3.2,P < 0.001). Patients in the high CD11 c expression group had a greater 3- and 5-year OS probability and longer median survival time compared with the low CD11 c expression group,(67.7% vs 39.2%; 51.4% vs 29.0%; 67.0 mo vs 28.0 mo; χ2 = 6.80,P = 0.009),and had a greater 3- and 5-year DFS probability and longer median DFS time(63.7% vs 24.0%; 49.1% vs 11.9%; 64.0 mo vs 18.0 mo; χ2 = 15.39,P < 0.001). Patients with high CD11 c high expression had a reduced risk of death(HR = 0.56,95%CI: 0.33-0.98,P < 0.05) and relapse(HR = 0.39,95%CI: 0.23-0.67,P < 0.01) compared with patients

关键词： CD11c Gastric cancer Dendritic cell Tumor microenv

Study of the vibrational photochemical reation of UF_6+HCl and its isotopic selectivity

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Chinese Journal of Chemistry 1993年第2期11卷 97-104页

作者： XU,Bao-Yu LIU,Yong DONG,wen-Bo ZHAO,wei hu,Jian-Xun ZHENG,Cheng-Fa Nuclear Science Department,Fudan University,Shanghai 200433 Nuclear Science Department Fudan University Shanghai 200433

The photochemical vibrational reaction of UF_6+HCl was investigated by exciting the ternary overtone of 3ν_3 of UF_6 in an intracavity CO laser *** was found that the rate of the laser-driven reaction was much greater than that of the thermal reaction and this photochemical process had an isotopic *** uranium isotope enrichment factors measured in experiments wore around 1,007 in a single step.

关键词： Study of the vibrational photochemical reation of UF6+HCl and its isotopic selectivity UF HCl

Double-balloon enteroscopy reliably directs surgical intervention for patients with small intestinal bleeding

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World Journal of Gastroenterology 2008年第12期14卷 1936-1940页

作者： Mou-Bin Lin Lu Yin Jian-wen Li wei-Guo hu Qian-Jian Qian Department of Surgery Ruijin Hospital Shanghai 200025China

AIM: To evaluate preoperative double-balloon enteroscopy for determining bleeding lesions of small intestine, thus directing selective surgical intervention. METHODS: We retrospectively reviewed 56 patients who underwent double-balloon enteroscopy to localize intestinal bleeding prior to surgical intervention, and compared enteroscopic findings with those of intraoperation to determine the accuracy of enteroscopy in identifying and localizing the sites of small intestinal bleeding. RESULTS: Double-balloon enteroscopy was performed in all 56 patients in a 30-mo period. A possible site of blood loss was identified in 54 (96%) patients. Enteroscopy provided accurate localization of the bleeding in 53 (95%) of 56 patients, but failed to disclose the cause of bleeding in 4 (7%). There was one case with negative intraoperative finding (2%). Resection of the affected bowel was carried out except one patient who experienced rebleeding after operation. Gastrointestinal stromal tumor (GIST) was most frequently diagnosed (55%). CONCLUSION: Double-balloon enteroscopy is a safe, reliable modality for determining bleeding lesion of small intestine. This technique can be used to direct selective surgical intervention.

关键词： Double-balloon enteroscopy Small intestinebleeding Surgery

Status of Intellectual Property Protection, Exploitation and Utilization of Germplasm Resources in Henan Province

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河南农业科学 2009年第9期38卷 26-30页

作者： wei wen-xing hu Lin hui-yong ZHANG Lei CHENG Ze-qiang Henan Academy of Agricultural Sciences Zhengzhou 450002 China

Natural germplasm resources are the material basis and precondition for living and development of humankind. It is also the important material for biology research. In the current paper, the practice and problems of collection, conservation, intellectual property protection and utilization of natural germplasm resources in Henan province were analyzed, and the corresponding countermeasures were suggested.

关键词：河南农业种质资源生态研究

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货币政策对企业债券信用利差的传导机制研究

统计与信息论坛 2018年第11期33卷 59-69页

作者：温湖炜曾裕峰汤伟南昌大学中国中部经济社会发展研究中心江西南昌330031 深圳证券交易所综合研究所广东深圳518038 中国金融期货交易所研发部上海200122

针对新常态下中国货币政策调控框架的演变特征,采用TVP-SVAR模型分析数量型和价格型货币政策工具对企业债券融资成本的传导效应及机制。结果表明:货币政策调控对企业债券信用利差的调节具有显著的时变特征,宽松的货币政策有利于降低实... 详细信息

针对新常态下中国货币政策调控框架的演变特征,采用TVP-SVAR模型分析数量型和价格型货币政策工具对企业债券融资成本的传导效应及机制。结果表明:货币政策调控对企业债券信用利差的调节具有显著的时变特征,宽松的货币政策有利于降低实体企业的融资成本;货币基准利率对债券市场的传导效率高于公开市场直接投放货币,价格型货币政策工具对企业信用利差的调节效应更为显著,数量型货币政策工具主要是满足央行"预微预调"的目的,在债券市场的传导效果并不理想;无论是信贷渠道还是利率渠道,价格型货币政策对中国企业债券的信用风险传导作用在日益提升,但是利率工具的短期作用效果不如中、长期,对实体经济的调节作用相对缓慢。刚性兑付是企业债券信用利差的屏障,影响了货币政策的效果。综合利用结构性和定向性货币工具组合,适度地向小微企业和高新技术企业倾斜,优化定向调控的货币政策的效果,才能达到降低实体企业债务融资成本的目的。

关键词：信用利差货币政策工具传导渠道 TVP-SVAR模型

CRYSTAL STRUCTURE OF ORGANOLANTHANIDE COMPLEX [Li+（DME）3]2[（CpNd）4（μ2-CH3）2（μ4-O）(μ2-Cl)6]2-

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Chinese Journal of Structural Chemistry 1990年第2期 140-144页

作者： Jin Zhong-Sheng Guan Jing-wen wei Ge-Cheng hu Jing-Yu Shen QiLaboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy ofSciences

The crystal and molecular structure of [Li+（DME）3]2[（CpNd）4 （μ2-CH3）2（μ4-O）（μ2-Cl）6]2as determined from single crystal X-ray diffraction. The complex crystallizes in the monoclinic space group P21/n with lattice parameters a= 14. 614（5）, b= 18. 683 （5）,c= 24. 595 （6） A, β = ,91-85（2）°, V = 6712（3） A3,2 = 4,DC = 1. 63g/cm3,F（000） = 3256,Mr=1650. 85. The structure was solved by direct methods and Fourier techniques and refined by least-squares to a final R=0. 047,RW = 0. 049 for 3761 with I>3σ（I）. The result revealed that the anion [（CpNd）4（μ4-O）（μ2-Cl）6（μ2-CH3）2]2- is composed of four neodymium （Ⅲ） atoms bridged by six Cl atoms, two methyl groups and one oxygen atom, and every Nd is bonded to a cyclopentadienyl group. The four Nd atoms form a distorted tetrahedron. The cations are composed of two Li+（DME）3 with average Li-O distance of 2. 120（40） A.

关键词： Li CI CpNd CRYSTAL STRUCTURE OF ORGANOLANTHANIDE COMPLEX DME Cl

数字基础设施与企业全要素生产率——来自中国上市公司的证据

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软科学 2022年第8期36卷 64-71页

作者：温湖炜钟启明南昌大学中国中部经济社会发展研究中心南昌330031 南昌大学经济管理学院南昌330031 中南财经政法大学金融学院武汉430073

基于2007-2020年中国A股上市企业数据,利用智慧城市建设的准自然实验,采用双重差分法考察数字基础设施建设对企业全要素生产率的综合影响。结果表明,数字基础设施建设对企业全要素生产率具有显著的正向作用,数字基础设施的生产率悖论不... 详细信息

基于2007-2020年中国A股上市企业数据,利用智慧城市建设的准自然实验,采用双重差分法考察数字基础设施建设对企业全要素生产率的综合影响。结果表明,数字基础设施建设对企业全要素生产率具有显著的正向作用,数字基础设施的生产率悖论不成立。进一步研究发现,促进研发创新、降低交易成本、提高管理效率是新型数字基础设施影响企业全要素生产率的作用路径。工业企业数字化转型更加依赖于新型数字基础设施的支撑效应,而服务业企业主要通过自身商业模式创新而对数字基础设施的依赖程度较低。

关键词：全要素生产率数字基础设施智慧城市产业数字化渗透效应

环境保护税改革能否撬动企业绿色技术创新--来自中国排污费征收标准变迁的启示

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贵州财经大学学报 2020年第3期 91-100页

作者：温湖炜钟启明南昌大学中国中部经济社会发展研究中心江西南昌330031 南昌大学经济管理学院江西南昌330031

基于环境税费征收标准调整的改革实践,采用倍差法考察环境税费政策干预的异质性效应,并探讨环境保护税改革对企业绿色技术创新的影响。结果表明,环境税费征收标准调整对企业绿色技术创新的广延边际和集约边际都存在显著的正向影响,支持... 详细信息

基于环境税费征收标准调整的改革实践,采用倍差法考察环境税费政策干预的异质性效应,并探讨环境保护税改革对企业绿色技术创新的影响。结果表明,环境税费征收标准调整对企业绿色技术创新的广延边际和集约边际都存在显著的正向影响,支持"波特假说";环境税费成本上升倒逼大中型企业绿色技术创新,但对小规模企业的影响不显著;环境税费征收标准调整政策对企业绿色技术创新的作用在高污染行业、政策执行力较强城市和实施绿色税收政策地区更为突出。优化环境保护税收体系和推进税制绿色化转型,有助于释放环境治理红利,但需要配套政策降低环保税对中小微企业造成的不利冲击。

关键词：环境保护税税制绿色化绿色全要素生产率绿色技术创新

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制造业数字化转型影响劳动收入份额吗?

产经评论 2023年第1期14卷 120-134页

作者：徐慧枫温湖炜中共宁波市委党校学报编辑部南昌大学经济管理学院

数字化转型如何影响劳动收入份额是数字经济赋能共同富裕所面临的现实问题。基于2010—2020年中国制造业上市公司面板数据,实证考察数字化转型对制造业企业劳动收入份额的影响。结果表明:制造业数字化转型对劳动收入份额有显著影响,并... 详细信息

数字化转型如何影响劳动收入份额是数字经济赋能共同富裕所面临的现实问题。基于2010—2020年中国制造业上市公司面板数据,实证考察数字化转型对制造业企业劳动收入份额的影响。结果表明:制造业数字化转型对劳动收入份额有显著影响,并不支持数字化转型抑制劳动要素收入从而恶化要素收入分配的观点;现阶段,数字化转型提升劳动收入份额的作用主要通过工资效应而不是就业效应,即数字化转型促进制造业企业劳动生产率提升,但未促进就业增长;数字化转型与劳动收入份额的关系存在产业结构层次、行业以及企业异质性,对于产业结构水平高地区、非技术密集型行业及资本密集程度低企业,数字化转型对劳动收入份额的提升作用更强;此外,数字化转型对高就业技能结构企业劳动收入份额的正向影响更强,制造业部门数字化转型对技能需求表现出“升级”特征而不是“极化”特征。因此,数智时代收入分配政策的完善与优化应关注劳动力技能与新兴数字技术的动态适配性。

关键词：数字化转型要素收入分配劳动收入份额要素禀赋升级