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Is TOL 1326–379 a Prototype ofγ-Ray Emitting FR0 Radio Galaxy?

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Research in Astronomy and Astrophysics 2022年第3期22卷 47-56页

作者： wen-jing fu Hai-Ming Zhang Jin Zhang Yun-Feng Liang Su Yao En-Wei Liang Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China School of Physics Beijing Institute of TechnologyBeijing 100081China Max-Planck-Institute für Radioastronomie Auf dem Hügel 69D-53121 BonnGermany

With the possible spacial association to the Fermi/LAT source 3 FGL J 1330.0-3818,TOL 1326-379 may be the first one that is identified as a 7-ray emitting Fanaroff-Riley type 0 radio galaxy(FRO RG).We analyze the~12 yr Fermi/LAT observation data of thisγ-ray source and examine its association to TOL *** show that theγ-ray source(named as J1331.0-3818)is tentatively detected with a TS value of 28.7,3 FGL J 1330.0-3818 is out of the 95%containment of J1331.0-3818,and their positions are spatially separated~0°.2.4 FGL J1331.3-3818 falls into the 68%containment of J1331.0-3818,suggesting that our result agrees with that reported in the Fourth Fermi LAT Source *** 1326-379 is out of the 95%containment of J1331.0-3818,and their positions are spatially separated~0°.4,indicating that the association between J1331.0-3818 and TOL 1326-379 is quite ***,we do not find other possible potential radio or X-ray counterpart within the circle centered at J1331.0-3818 with a radius of 0°.*** spectral energy distribution(SED)of TOL 1326-379 shows a bimodal feature as seen in theγ-ray emitting *** fit the SED with the one-zone leptonic model and find that the average energy spectrum of J1331.0-3818 agrees with the model *** that J1331.0-3818 is an unidentified 7-ray source,we derive the upper-limit of theγ-ray flux for TOL *** is not tight enough to exclude this possibility with the SED *** on these results,we cautiously argue that theγ-ray source J1331.0-3818 is associated with TOL 1326-379 and its jet radiation physic is similar to thoseγ-ray emitting RGs.

关键词： radiation mechanisms:non-thermal galaxies:active galaxies galaxies:radio jets gamma-rays:galaxies

Comparison of two vasopressor protocols for preventing hypotension post-spinal anesthesia during cesarean section: a randomized controlled trial

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Chinese Medical Journal 2021年第7期134卷 792-799页

作者： Qian-Qian Fan Yong-Hui Wang jing-wen fu Hai-Long Dong Man-Ping Yang Duo-Duo Liu Xiao-Fan Jiang Zhi-Xin Wu Li-Ze Xiong Zhi-Hong Lu Department of Anesthesiology and Perioperative Medicine Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Gynecology and Obstetrics Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Neurosurgery Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Anesthesiology and Translational Research Institute of Brain and Brain-like Intelligence Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200081China.

Background:Norepinephrine infusion decreases hypotension after spinal anesthesia during cesarean *** study aimed to compare the efficacy of norepinephrine infusion and ephedrine bolus against post-spinal hypotension in ***:In this double-blinded,randomized controlled clinical trial,parturients scheduled for elective cesarean section were randomly allocated to receive norepinephrine infusion(0.05μg·kg^(-1)·min^(-1))just before spinal anesthesia continuing for 30 min or ephedrine bolus(0.15 mg/kg)just before spinal anesthesia.A rescue bolus(5μg norepinephrine for the norepinephrine group,and 5 mg ephedrine for the ephedrine group)was administered whenever hypotension *** primary outcome was the incidence of hypotension within 30 min of spinal anesthesia *** outcomes included maternal and neonatal outcomes 30 min after spinal block,and neonatal cerebral oxygenation 10 min after ***:In total,190 patients were enrolled;of these patients,177 were included in the final *** patients suffered hypotension in the norepinephrine group than in the ephedrine group(29.5%vs.44.9%,odds ratio[OR]:0.51,95%confidence interval[CI]:0.28-0.95,P=0.034).Moreover,the tachycardia frequency was lower in the norepinephrine group than in the ephedrine group(OR:0.22,95%CI:0.11-0.44,Pfusion compared to ephedrine bolus resulted in less hypotension and tachycardia,and exhibited potential neonatal benefits.

关键词： Hypotension Spinal anesthesia Norepinephrine Ephedrine Cesarean section

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带有年龄信息的PCA人脸识别技术

数学的实践与认识 2018年第6期48卷 118-130页

作者：陈文兴岳靖付浩宁夏大学数学统计学院

基于主成分分析（PCA）的人脸识别算法．其中包括K—L变换、SVD分解、特征脸的构建、人脸年龄估计和人脸识别等过程．使用了Manhattan、Euclidean、Cosine这3种距离进行判别，实验得出Euclidean最优，最后，用MATLAB编程计算出人脸识别... 详细信息

基于主成分分析（PCA）的人脸识别算法．其中包括K—L变换、SVD分解、特征脸的构建、人脸年龄估计和人脸识别等过程．使用了Manhattan、Euclidean、Cosine这3种距离进行判别，实验得出Euclidean最优，最后，用MATLAB编程计算出人脸识别的准确率．结合柔性模型（AAM）和分层训练样本实现带有年龄信息的人脸识别技术；同一年龄段内训练样本数越多，识别率越高．

关键词：人脸预处理 PCA人脸识别柔性模型特征脸 K—L变换

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway

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Neural Regeneration Research 2025年第11期20卷 3245-3258页

作者： Jiayi Wang Mengke Zhao Dong fu Meina Wang Chao Han Zhongyue Lv Liang Wang jing Liu Stem Cell Clinical Research Center The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning ProvinceChina Dalian Innovation Institute of Stem Cell and Precision Medicine DalianLiaoning ProvinceChina Institute(College)of Integrative Medicine Dalian Medical UniversityDalianLiaoning ProvinceChina

Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem cell therapy and advancing the frontiers of stem cell-derived *** lays a foundation for the development of potentially potent new treatment modalities for ischemic ***,the precise mechanisms underlying the efficacy and safety of human neural stem cell-derived extracellular vesicles remain unclear,presenting challenges for clinical *** promote the translation of therapy based on human neural stem cell-derived extracellular vesicles from the bench to the bedside,we conducted a comprehensive preclinical study to evaluate the efficacy and safety of human neural stem cell-derived extracellular vesicles in the treatment of ischemic *** found that administration of human neural stem cell-derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal *** human neural stem cell-derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase,mammalian target of rapamycin,and protein kinase B,and these effects were reversed by treatment with a phosphoinositide 3-kinase *** findings suggest that human neural stem cell-derived extracellular vesicles play a neuroprotective role in ischemic stroke through activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling ***,we showed that human neural stem cell-derived extracellular vesicles have a good in vivo safety ***,human neural stem cell-derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.

关键词： behavior exosome extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)

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光敏电阻的自动测试与分选

制造业自动化 2009年第7期31卷 79-81页

作者：景文富刘明黎李宇明河南工业职业技术学院

介绍光敏电阻的自动测试与分选系统的结构及工作流程,本系统具有机构简单、效率高、造价低、使用方便等特点,取得了一定的经济效益。

关键词：光敏电阻 R/V转换电路恒流源亮电阻暗电阻

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan Sun Lingyun Nie jing Zhang Xue Fang Hongmei Luo Chuanhai fu Zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

Anti-breast cancer effect of quercetin nanoparticles based on MOFs for chemo-phototherapy and heat shock proteins inhibition

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Nano Research 2025年第1期18卷 545-558页

作者： Rongyue Zhu Shilang Liao Mengru Cai Dongge Yin Tingting fu jing Liu Yuji Du Jiahui Kong Rongrong Chang Jian Ni Xingbin Yin Beijing University of Chinese Medicine Fangshan DistrictBeijing 102488China

Phototherapy, including photodynamic therapy(PDT) and photothermal therapy (PTT), is a promisingmethod of tumor treatment, which has the advantages ofstrong specificity and small side effects. However, PDT willaggravate the hypoxic environment in tumor cells, and PTTwill lead to heat-resistant reaction, both of which will make theorganism quickly produce heat shock proteins (HSPs) toprotect itself, thus seriously hindering the therapeuticefficiency of phototherapy. As a natural HSPs inhibitor,quercetin (QR) provides a feasible way to solve this ***, a kind of metal organic framework (MOF), Fe-TCPP(FT), was used as a delivery material and photosensitizer tobuild a chemo-phototherapy platform, and QR was used as achemotherapy drug and HSPs inhibitor. On this basis, the nanoparticles (NPs) were modified with PEG-CPP30 (a cellpenetratingpeptide that specifically recognizes human breast cancer MCF-7 cells), which showed excellent targetingcapacity and biocompatibility. The combination of chemotherapy and phototherapy significantly improved the anti-cancereffect. At the same time, NPs also showed prominent anti-HSPs effect. The effective connection of the two played acomplementary role in the process of tumor treatment, which provided a new strategy for the accurate and efficienttreatment of tumors in the future.

关键词： quercetin Fe-metal organic frameworks(MOFs) phototherapy anti-cancer heat shock proteins inhibition

Reducing the measurement errors in nonadiabatic holonomic quantum computers

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 64-70页

作者： Guo-fu Xu Department of Physics Shandong University

Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum *** quantum computation has entered the noisy intermediate-scale era, building accurate intermediate-scale nonadiabatic holonomic quantum computers is clearly necessary. Given that measurements are the sole means of extracting information, they play an indispensable role in nonadiabatic holonomic quantum computers. Accordingly, developing methods to reduce measurement errors in nonadiabatic holonomic quantum computers is of great importance. However, while much attention has been given to the research on nonadiabatic holonomic gates, the research on reducing measurement errors in nonadiabatic holonomic quantum computers is severely lacking. In this study, we propose a measurement error reduction method tailored for intermediate-scale nonadiabatic holonomic quantum computers. The reason we say this is because our method can not only reduce the measurement errors in the computer but also be useful in mitigating errors originating from nonadiabatic holonomic gates. Given these features,our method significantly advances the construction of accurate intermediate-scale nonadiabatic holonomic quantum computers.

关键词： quantum holonomy quantum computation measurement errors

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高精度电容测微仪的自校正方法

计量学报 2001年第3期22卷 181-184页

作者：李建文付敬业张洪刚赵玉春郑义忠叶声华天津大学精密测试技术及仪器国家重点实验室天津300072

本文详细叙述了一种电容测微仪的自校正方法 ,并就其工作原理进行了讨论。采用这种方法不需要其它高精度标准 ,仅利用两相同精度的电容传感器和自校正装置即可进行多次相互校准 ,最终得到各自准确度达到自身能力极限的校正结果。

关键词：电容测微仪自校正线性误差工作原理试验装置电容传感器