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Idiopathic mesenteric phlebosclerosis missed by a radiologist at initial diagnosis: A case report

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World Journal of Clinical Cases 2024年第10期12卷 1810-1816页

作者： Min Wang Yu-Xia Wan Jin-wen liao Fei Xiong Department of Gastroenterology Changning County People’s HospitalYibin 644300Sichuan ProvinceChina Department of Gastroenterology Qianwei People’s HospitalLeshan 614400Sichuan ProvinceChina Department of Gastroenterology The People’s Hospital of Jianyang CityChengdu 641400Sichuan ProvinceChina Department of Gastroenterology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610000Sichuan ProvinceChina

BACKGROUND Idiopathic mesenteric phlebosclerosis(IMP)is a rare type of ischemic colitis characterized by thickening of the wall of the right hemicolon and calcification,sclerosis,and fibrosis of mesenteric *** diagnosis of IMP is based on typical clinical features and imaging *** report a case of IMP that was initially missed by the *** SUMMARY A 77-year-old woman was admitted to the hospital due to chronic diarrhea for over 2 *** had been consuming Chinese patent medicines(CPM)containing fructus gardeniae for more than 15 *** revealed an edematous mucosa,bluish-purple discoloration,erosions,and ulcerations throughout the colorectal *** computed tomography(CT)showed diffuse mural thickening of the entire colorectum,with tortuous thread-like calcifications in the right hemicolon,left hemicolon,and *** of the calcifications were located in the mesenteric *** diagnosis of IMP was established based on medical history,colonoscopy,CT findings,and histopathological *** patient was treated conservatively with papaverine and rifaximin,and CPM was *** diarrhea symptoms improved,indicating the effectiveness of the *** the next several years,she took opium alkaloids for an extended period and did not require hospitalization for the aforementioned gastrointestinal *** IMP is a rare gastrointestinal disease affecting Asian populations,possibly related to long-term herbal medicine *** imaging analysis is crucial for diagnosis,but insufficient understanding of the disease can lead to misdiagnosis or missed *** strategies should be personalized.

关键词： Idiopathic mesenteric phlebosclerosis Computed tomography Colonoscopy Chinese patent medicines Fructus gardeniae Case report

Stable Cycling of All-Solid-State Lithium Batteries Enabled by Cyano-Molecular Diamond Improved Polymer Electrolytes

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Nano-Micro Letters 2024年第10期16卷 561-575页

作者： Yang Dai Mengbing Zhuang Yi-Xiao Deng Yuan liao jian Gu Tinglu Song Hao Yan Jin-Cheng Zheng Department of Chemical Engineering Shanghai UniversityShangda Road 99Shanghai 200444People's Republic of China Department of Physics Xiamen UniversityXiamen 361005People's Republic of China Experimental Center of Advanced Materials School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People's Republic of China Department of Physics and Department of New Energy Science and Engineering Xiamen University Malaysia43900 SepangMalaysia

The interfacial instability of the poly(ethylene oxide)(PEO)-based electrolytes impedes the long-term cycling and further application of all-solid-state lithium metal *** this work,we have shown an effective additive 1-adaman-tanecarbonitrile,which con-tributes to the excellent per-formance of the poly(ethylene oxide)-based *** to the strong interaction of the 1-Adamantanecarboni-trile to the polymer matrix and anions,the coordination of the Li^(+)-EO is weakened,and the binding effect of anions is strengthened,thereby improving the Li^(+)conductivity and the electrochemical *** diamond building block on the surface of the lithium anode can sup-press the growth of lithium ***,the 1-Adamantanecarbonitrile also regulates the formation of LiF in the solid electrolyte interface and cathode electrolyte interface,which contributes to the interfacial stability(especially at high voltages)and protects the electrodes,enabling all-solid-state batteries to cycle at high voltages for long periods of ***,the Li/Li symmetric cell undergoes long-term lithium plating/stripping for more than 2000 h.1-Adamantanecarbonitrile-poly(ethylene oxide)-based LFP/Li and 4.3 V Ni_(0.8)Mn_(0.1)Co_(0.1)O_(2)/Li all-solid-state batteries achieved stable cycles for 1000 times,with capacity retention rates reaching 85%and 80%,respectively.

关键词： 1-Adamantanecarbonitrile(ADCN) Poly(ethylene oxide) All-solid-state batteries Interfacial stability High voltage

A novel method for extracting and optimizing the complex permittivity of paper-based composites based on an artificial neural network model

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Science China Technological Sciences 2024年第10期67卷 3190-3204页

作者： XIA ChenBin SHEN JunYi liao ShaoWei WANG Yi HUANG ZhengSheng XUE Quan TANG Min LONG Jin HU jian School of Light Industry and Engineering South China University of Technology School of Electronic and Information Engineering South China University of Technology

Measuring the complex permittivity of ultrathin, flexible materials with a high loss tangent poses a substantial challenge with precision using conventional methods, and verifying the accuracy of test results remains difficult. In this study, we introduce a methodology based on a back-propagation artificial neural network(ANN) to extract the complex permittivity of paper-based composites(PBCs). PBCs are ultrathin and flexible materials exhibiting considerable complex permittivity and dielectric loss tangent. Given the absence of mature measurement methods for PBCs and a lack of sufficient data for ANN training, a mapping relationship is initially established between the complex permittivity of honeycomb-structured microwave-absorbing materials(HMAMs, composed of PBCs) and that of PBCs using simulated data. Leveraging the ANN model, the complex permittivity of PBCs can be extracted from that of HMAMs obtained using standard measurement. Subsequently, two published methods are cited to illustrate the accuracy and advancement of the results obtained using the proposed approach. Additionally, specific error analysis is conducted, attributing discrepancies to the conductivity of PBCs, the homogenization of HMAMs, and differences between the simulation model and actual objects. Finally, the proposed method is applied to optimize the cell length parameters of HMAMs for enhanced absorption performance. The conclusion discusses further improvements and areas for extended research.

关键词： paper-based composite honeycomb complex permittivity artificial neural networks inverse modeling

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N-glycan biosignatures as a potential diagnostic biomarker for earlystage pancreatic cancer

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 659-669页

作者： Yan-Rong wen Xia-wen Lin Yu-wen Zhou Lei Xu Jun-Li Zhang Cui-Ying Chen jian He Department of Nuclear Medicine Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008Jiangsu ProvinceChina Department of Research and Development Sysdiagno(Nanjing)Biotech Co.LtdNanjing 210008Jiangsu ProvinceChina

BACKGROUND Pancreatic ductal adenocarcinoma(PDAC)has a poor prognosis,with a 5-year survival rate of less than 10%,owing to its late-stage *** detection of pancreatic cancer(PC)can significantly increase survival *** To identify the serum biomarker signatures associated with early-stage PDAC by serum N-glycan *** An extensive patient cohort was used to determine a biomarker signature,in-cluding patients with PDAC that was well-defined at an early stage(stages I and II).The biomarker signature was derived from a case-control study using a case-cohort design consisting of 29 patients with stage I,22 with stage II,4 with stage III,16 with stage IV PDAC,and 88 *** used multiparametric analysis to identify early-stage PDAC N-glycan signatures and developed an N-glycan sig-nature-based diagnosis model called the“Glyco-model”.RESULTS The biomarker signature was created to discriminate samples derived from patients with PC from those of controls,with a receiver operating characteristic area under the curve of *** addition,the biomarker signature combined with cancer antigen 19-9 could discriminate patients with PDAC from controls,with a receiver operating characteristic area under the curve of ***-model demonstrated favorable diagnostic performance in all stages of *** diagnostic sensitivity for stage I PDAC was 89.66%.Core Tip:This study employed a patient cohort to investigate the N-glycan signature of early-stage pancreatic cancer(PC).Serum N-glycans analysis was conducted to identify the serum biomarker signature associated with early-stage pancreatic ductal adenocarcinoma(PDAC),resulting in the identification of nine early-stage PDAC N-glycan ***,utilizing these biosignatures,a diagnostic model named the“Glyco-model”was developed,demonstrating promising diagnostic performance across all stages of *** study revealed that the diagnostic sensitivity for stage I PDAC was determined to be 89.66%.Co

关键词： Glycomics N-glycans Biomarkers Pancreatic cancer Predictive modeling

One-year results for myopia control of orthokeratology with different back optic zone diameters: a randomized trial using a novel multispectral-based topographer

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 324-330页

作者： wen-Ting Tang Xiang-Ning Luo wen-Jing Zhao Jia liao Xin-Yue Xu Hui-Dan Zhang Li Zhang Department of Ophthalmology the First Affiliated Hospital of Chengdu Medical CollegeChengdu Medical CollegeChengdu 610500Sichuan ProvinceChina

AIM:To present the 1-year results of a prospective cohort study investigating the efficacy,potential mechanism,and safety of orthokeratology(ortho-k)with different back optic zone diameters(BOZD)for myopia control in ***:This randomized clinical study was performed between Dec.2020 and *** were randomly assigned to three groups wearing ortho-k:5 mm BOZD(5-MM group),5.5 mm BOZD(5.5-MM group),and 6 mm BOZD(6-MM group).The 1-year data were recorded,including axial length,relative peripheral refraction(RPR,measured by multispectral refractive topography,MRT),and visual *** contrast sensitivity(CS)was evaluated by CSV-1000 instrument with spatial frequencies of 3,6,12,and 18 cycles/degree(c/d);the corneal higher-order aberrations(HOAs)were measured by iTrace aberration *** one-way ANOVA was performed to assess the differences between the three *** correlation between the change in AL and RPR was calculated by Pearson’s correlation ***:The 1-year results of 20,21,and 21 subjects in the 5-MM,5.5-MM,and 6-MM groups,respectively,were *** were no statistical differences in baseline age,sex,or ocular parameters between the three groups(all P>0.05).At the 1-year visit,the 5-MM group had lower axial elongation than the 6-MM group(0.07±0.09 vs 0.18±0.11 mm,P=0.001).The 5-MM group had more myopic total RPR(TRPR,P=0.014),with RPR in the 15°–30°(RPR 15–30,P=0.015),30°–45°(RPR 30–45,P=0.011),temporal(RPR-T,P=0.008),and nasal area(RPR-N,P<0.001)than the 6-MM *** 15–30 in the 5.5-MM group was more myopic than that in the 6-MM group(P=0.002),and RPR-N in the 5-MM group was more myopic than that in the 5.5-MM group(P<0.001).There were positive correlations between the axial elongation and the change in TRPR(r=0.756,P<0.001),RPR 15–30(r=0.364,P=0.004),RPR 30–45(r=0.306,P=0.016),and RPR-N(r=0.253,P=0.047).The CS decreased at 3 c/d(P<0.001),and the corneal HOAs increased in the 5-MM group(P=0.030).CONCL

关键词： relative peripheral refraction orthokeratology myopia back optic zone diameter axial length multispectral refractive topography

Beware of the serious harm of veterinary drug poisoning:a case report

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World Journal of Emergency Medicine 2024年第2期15卷 153-155页

作者： Ping Dai Jin Sun Tongyue Zhang Zhiqiang Zhou Zixi wen Tianzi jian Aerbusili Genjiafu Baotian Kan Xiangdong jian Department of Poisoning and Occupational Diseases Emergency MedicineQilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012China Emergency Department Affiliated the Jianhu Clinical Medical College of Yangzhou UniversityYancheng 224700China Department of Occupational and Environmental Health School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012China School of Nursing and Rehabilitation Cheeloo College of MedicineShandong UniversityNursing Theory&Practice Innovation Research Center of Shandong UniversityJinan 250012China Department of Geriatric Medicine Qilu HospitalNursing Theory Innovation and Research Center of Shandong UniversityCheeloo College of MedicineShandong UniversityJinan 250012China

Veterinary drugs are substances(including pharmaceutical feed additives)used to prevent,treat,and diagnose diseases or regulate the physiological functions of *** drug poisoning in humans is relatively rare both in China and the rest of the ***,we report a case of death from veterinary drug poisoning from ***-closantel is a broad-spectrum antiparasitic drug,which has high efficacy against a variety of trematodes and nematodes.

关键词： drug drugs diseases

SnS_(2) nanosheets decorated SnO_(2) hollow multishelled nanostructures for enhanced sensing of triethylamine gas

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Rare Metals 2024年第5期43卷 2339-2348页

作者： wen-Di Liu Ya Xiong Ao Shen Xin-Zhen Wang Xiao Chang wen-Bo Lu jian Tian School of Materials Science and Engineering Shandong University of Science and TechnologyQingdao 266590China College of Physics Qingdao UniversityQingdao 266071China Zernike Institute for Advanced Materials University of Groningen9747 AG GroningenThe Netherlands

Highly sensitive,fast and low-temperature detection of triethylamine(TEA)gas based on SnO_(2) is attractive yet remains ***,SnS_(2) nanosheets(NSs)/SnO_(2) hollow multishelled structures(HoMSs)-based sensors are designed by the synthesis of SnO_(2) HoMSs,followed by in situ sulfuration with *** varying the thioacetamide levels,Sn S_(2)/SnO_(2) heterostructures with different SnS_(2) contents were obtained and their TEA gas sensing performances were investigated.

关键词： SnS attractive sheets

Carbene-catalyzed enantioselective seleno-Michael addition as access to antimicrobial active Se-containing heterocycles

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Science China Chemistry 2024年第7期67卷 2199-2205页

作者： Hongyan Long Sha Zhao Chunyan jian Xiuli Wu Fengfei Lu Minghong liao Fengrui Che Xingxing Wu Yonggui Robin Chi State Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityGuiyang 550025China School of Chemistry Chemical Engineeringand BiotechnologyNanyang Technological UniversitySingapore 637371Singapore

Organoseleniums exhibit a diverse set of biological activities that are pivotal for drug discovery and are widely explored in synthetic chemistry and material *** many transformations have been developed for non-enantioselective C–Se bond formations,the catalyst-controlled stereoselective preparation of chiral organoseleniums continues to be of considerable *** particular,there are limited studies on the enantioselective seleno-Michael addition reactions to access chiral selenium functional ***,we disclose a carbene-catalyzed highly enantioselective nucleophilic C–Se bond construction through formal[3+3]annulations between selenocarboxamides and bromoenals,affording seleno-thiazinone products with good yields and excellent *** choice of a weak inorganic base was pivotal to suppressing the unproductive racemization and decomposition of the selenium ***,the catalytically generated chiral selenium-containing heterocyclic products feature remarkable antimicrobial activities that could serve as promising lead scaffolds for further agrochemical development.

关键词： seleno-Michael addition organocatalysis N-heterocyclic carbene seleno-heterocycles antimicrobial activity

Colorectal cancer screening:The value of early detection and modern challenges

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World Journal of Gastroenterology 2024年第20期30卷 2726-2730页

作者： jian Li Zhi-Peng Li wen-Jie Ruan Wei Wang Department of Interventional Oncology Municipal Hospital Affiliated to Taizhou UniversityTaizhou 318000Zhejiang ProvinceChina School of Medicine Taizhou UniversityTaizhou 318000Zhejiang ProvinceChina

The screening of colorectal cancer(CRC)is pivotal for both the prevention and treatment of this disease,significantly improving early-stage tumor detection *** advancement not only boosts survival rates and quality of life for patients but also reduces the costs associated with ***,the adoption of CRC screening methods faces numerous challenges,including the technical limitations of both noninvasive and invasive methods in terms of sensitivity and ***,socioeconomic factors such as regional disparities,economic conditions,and varying levels of awareness affect screening *** coronavirus disease 2019 pandemic further intensified these challenges,leading to reduced screening participation and increased waiting ***,the growing prevalence of early-onset CRC necessitates innovative screening *** response,research into new methodologies,including artificial intelligence-based systems,aims to improve the precision and accessibility of *** measures by governments and health organizations to enhance CRC screening efforts are underway,including increased advocacy,improved service delivery,and international *** role of technological innovation and global health collaboration in advancing CRC screening is *** such as artificial intelligence and gene sequencing are set to revolutionize CRC screening,making a significant impact on the fight against this *** the rise in early-onset CRC,it is crucial for screening strategies to continually evolve,ensuring their effectiveness and applicability.

关键词： Colorectal cancer Early detection Economic implications Noninvasive tests Quality of life Survival rates Therapeutic modalities Technical challenges