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Passive activity enhances residual control ability in patients with complete spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He jia Zheng Hongming Bai jia-Sheng rao Guiyun Song Wei Song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng Bo Shao Chao-Min Xu Ke Wang jia-Zhu wen Li-Kang Luo jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report

Visualization of the protective role of estrogen against female liver fibrosis via an ER viscosity NIR fluorescent probe

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Science China Chemistry 2025年第1期 360-368页

作者： Zheng Liu Changyu Zhang Zipeng Li Wanying Ma jia Liu Xiang Xia Ning Xu wen Sun jianjun Du jiangli Fan Xiaojun Peng State Key Laboratory of Fine Chemicals Dalian University of Technology Ningbo Institute of Dalian University of Technology

Endoplasmic reticulum(ER) viscosity has emerged as a new potential biomarker for hepatic fibrosis(HF). Herein, we report the first ER-targeting viscosity-responsive near-infrared(NIR) fluorescent probe HBT-PP for investigations of HF *** twisted intramolecular charge transfer(TICT) and the excited state intramolecular proton transfer(ESIPT) are combined to endow HBT-PP with the selective response towards viscosity(～62-fold) and a super large stokes shift(～320 nm). HBT-PP mainly targets organelle ER and is able to image the drug-or alcohol-induced viscosity elevation in living cells. Significantly,HBT-PP was successfully applied to visualize the gender difference in HF and the protective role of estrogen in restraining HF progression. Of note, after 10 min of stain with HBT-PP, HF lesions showed a stage-based response, indicating the potential of this probe in fast and early diagnosis of HF. These results clearly demonstrated the promising application of HBT-PP as a new tool for exploring ER viscosity-involved physiological and pathological processes.

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Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li wen‑Xia Su jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

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World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： Yang-Zheng Lan Zheng Wu wen-jia Chen Xin-Ning Yu Hua-Tao Wu Jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

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基于隐性句逗号识别的汉语长句机器翻译

外语学刊 2025年第1期 39-46页

作者：冯文贺李熳佳张文娟广东外语外贸大学外国语言学及应用语言学研究中心语言工程与计算实验室广州510420 广州理工学院计算机科学与工程学院广州510420

长句翻译一直是机器翻译的难题。本文根据汉语中相当数量的逗号和句号可相互转化的特点,提出“隐性句号”和“隐性逗号”概念,并实现其自动识别,以将汉语长句变为短句用于汉英机器翻译。为此,首先通过人工与半监督学习结合方法构建一个... 详细信息

长句翻译一直是机器翻译的难题。本文根据汉语中相当数量的逗号和句号可相互转化的特点,提出“隐性句号”和“隐性逗号”概念,并实现其自动识别,以将汉语长句变为短句用于汉英机器翻译。为此,首先通过人工与半监督学习结合方法构建一个隐性句逗数据集,实现基于预训练模型的隐性句逗识别方法,其中性能最好的Hierarchical BERT作为后续应用模型。进而,实现基于隐性句逗识别的汉英机器翻译方法。在新闻和文学公开翻译测试语料上基于预训练机器翻译模型的实验表明,对于汉语长句的英译,本文方法相比基准翻译的BLEU值整体有所提高,而且在相对稳健机器翻译模型上,呈现为句子越长本文方法效果越明显。

关键词：机器翻译长句翻译隐性句逗号汉语长句逗号识别句内标点

Superior sodium and lithium storage in strongly coupled amorphous Sb2S3 spheres and carbon nanotubes

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International Journal of Minerals,Metallurgy and Materials 2021年第7期28卷 1194-1203页

作者： Qiong jiang wen-qi Zhang jia-chang Zhao Pin-hua rao jian-feng Mao School of Chemistry and Chemical Engineering Shanghai University of Engineering ScienceShanghai 201620China Institute for Superconducting and Electronic Materials Australian Institute for Innovative MaterialsUniversity of WollongongWollongongNew South WalesAustralia

A facile one-step strategy involving the reaction of antimony chloride with thioacetamide at room temperature is successfully de-veloped for the synthesis of strongly coupled amorphous Sb_(2)S_(3)spheres and carbon nanotubes(CNTs).Benefiting from the unique amorphous structure and its strongly coupled effect with the conductive network of CNTs,this hybrid electrode(Sb_(2)S_(3)@CNTs)exhibits remarkable sodi-um and lithium storage properties with high capacity,good cyclability,and prominent rate *** sodium storage,a high capacity of 814 mAh·g^(−1)at 50 mA·g^(−1)is delivered by the electrode,and a capacity of 732 mAh·g^(−1)can still be obtained after 110 *** up to 2000 mA·g^(−1),a specific capacity of 584 mAh·g^(−1)can be *** lithium storage,the electrode exhibits high capacities of 1136 and 704 mAh·g^(−1)at 100 and 2000 mA·g^(−1),***,the cell holds a capacity of 1104 mAh·g^(−1)under 100 mA·g^(−1)over 110 *** preparation and remarkable electrochemical properties make the Sb_(2)S_(3)@CNTs electrode a promising anode for both sodium-ion(SIBs)and lithium-ion batteries(LIBs).

关键词： amorphous antimony sulfide spheres carbon nanotubes sodium-ion batteries lithium-ion batteries electrochemical performance

Tree species classification in an extensive forest area using airborne hyperspectral data under varying light conditions

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Journal of Forestry Research 2023年第5期34卷 1359-1377页

作者： wen jia Yong Pang Institute of Forest Resource Information Techniques Chinese Academy of ForestryBeijing 100091People’s Republic of China Key Laboratory of Forestry Remote Sensing and Information System National Forestry and Grassland AdministrationBeijing 100091People’s Republic of China

Although airborne hyperspectral data with detailed spatial and spectral information has demonstrated significant potential for tree species classification,it has not been widely used over large areas.A comprehensive process based on multi-flightline airborne hyperspectral data is lacking over large,forested areas influenced by both the effects of bidirectional reflectance distribution function(BRDF)and cloud shadow *** this study,hyperspectral data were collected over the Mengjiagang Forest Farm in Northeast China in the summer of 2017 using the Chinese Academy of Forestry's LiDAR,CCD,and hyperspectral systems(CAF-LiCHy).After BRDF correction and cloud shadow detection processing,a tree species classification workflow was developed for sunlit and cloud-shaded forest areas with input features of minimum noise fraction reduced bands,spectral vegetation indices,and texture *** indicate that BRDF-corrected sunlit hyperspectral data can provide a stable and high classification accuracy based on representative training ***-shaded pixels also have good spectral separability for species *** red-edge spectral information and ratio-based spectral indices with high importance scores are recommended as input features for species classification under varying light *** to the classification accuracies through field survey data at multiple spatial scales,it was found that species classification within an extensive forest area using airborne hyperspectral data under various illuminations can be successfully carried out using the effective radiometric consistency process and feature selection strategy.

关键词： Tree species classification BRDF effects Cloud shadow Airborne hyperspectral data Random forest

Temporal and spatial variations in extreme temperatures in the Qilian Mountains-Hexi Corridor over the period 1960-2013

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Journal of Mountain Science 2016年第12期13卷 2224-2236页

作者： jia wen-xiong College of Geography and Environment Science Northwest Normal University

Based on daily maximum and minimum temperatures at 18 meteorological stations in the Qilian Mountains and Hexi Corridor between 1960 and 2013,temporal and spatial variations in extreme temperatures were analysed using linear trends,tenpoint moving averages and the Mann-Kendall *** results are as follows:The trends in the majority of the extreme temperature indices were statistically significant,and the changes in the extreme temperatures were more obvious than the changes in the extreme *** trends were different for each season,and the changes in rates and intensities in summer and autumn were larger than those in spring and *** the cold indices,the magnitudes and trends of the changes in the warm indices were larger and more significant in the Hexi Corridor than in the Qilian *** changes were detected in the majority of the extreme temperature indices,and the extreme cold indices usually occurred earlier than the changes in the extreme warm *** abrupt changes in the extreme temperatures in winter were the earliest among the four seasons,indicating that these temperature changes were the most sensitive to global climate *** timing of the abrupt changes in certain indices was consistent throughout the study area,but the changes in the cold indices in the Hexi Corridor occurred approximately four years before those in the Qilian ***,the changes in the warm indices in the western Hexi Corridor preceded those of the other regions.

关键词： Extreme temperature Interannual change Climate change Qilian Mountains Hexi Corridor