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循环经济的内涵及评价指标体系研究

包装工程 2005年第6期26卷 200-201页

作者：戴佩华重庆工商大学重庆400020

循环经济是当前世界经济发展的主要方向,已被我国确定为今后经济的发展模式。包装工业在上世纪90年代就已提出大力发展绿色包装的口号,绿色包装和循环经济具有相同的本质,因此本文以包装工业为点,探讨循环经济的内涵,基本原则和评价指... 详细信息

循环经济是当前世界经济发展的主要方向,已被我国确定为今后经济的发展模式。包装工业在上世纪90年代就已提出大力发展绿色包装的口号,绿色包装和循环经济具有相同的本质,因此本文以包装工业为点,探讨循环经济的内涵,基本原则和评价指标体系。

关键词：循环经济资源 “3R”原则评价指标体系

Combinational benefit of antihistamines and remdesivir for reducing SARS-CoV-2 replication and alleviating inflammation-induced lung injury in mice

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Zoological Research 2022年第3期43卷 457-468页

作者： Meng-Li Wu Feng-Liang Liu Jing Sun Xin Li Jian-Ru Qin Qi-Hong Yan Xia Jin Xin-wen Chen Yong-Tang Zheng Jin-Cun Zhao Jian-hua Wang College of Life Science Henan Normal UniversityXinxiangHenan 453007China Guangzhou Institutes of Biomedicine and Health Chinese Academy of SciencesGuangzhouGuangdong 510530China Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthFirst Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510182China University of Chinese Academy of Sciences Beijing 100049China

COVID-19 is an immune-mediated inflammatory disease caused by SARS-CoV-2 infection,the combination of anti-inflammatory and antiviral therapy is predicted to provide clinical *** recently demonstrated that mast cells(MCs)are an essential mediator of SARS-CoV-2-initiated *** also showed that spike protein-induced MC degranulation initiates alveolar epithelial inflammation for barrier disruption and suggested an off-label use of antihistamines as MC stabilizers to block degranulation and consequently suppress inflammation and prevent lung *** this study,we emphasized the essential role of MCs in SARS-CoV-2-induced lung lesions in vivo,and demonstrated the benefits of co-administration of antihistamines and antiviral drug remdesivir in SARS-CoV-2-infected ***,SARSCoV-2 spike protein-induced MC degranulation resulted in alveolar-capillary injury,while pretreatment of pulmonary microvascular endothelial cells with antihistamines prevented adhesion junction disruption;predictably,the combination of antiviral drug remdesivir with the antihistamine loratadine,a histamine receptor 1(HR1)antagonist,dampened viral replication and inflammation,thereby greatly reducing lung *** findings emphasize the crucial role of MCs in SARS-CoV-2-induced inflammation and lung injury and provide a feasible combination antiviral and anti-inflammatory therapy for COVID-19 treatment.

关键词： SARS-CoV-2 Mast cell Remdesivir Antihistamine Combinational therapy

High rank coalbed methane desorption characteristic and its application in production in Qinshui basin

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Journal of Coal Science & Engineering(China) 2013年第3期19卷 321-324页

作者： Bo WANG Fen-Jin SUN Feng-Yin XU Bo JIANG Zhi-hua SONG Jun-Hui wen Yang ZHAO School of Energy Resources China University of Geoseiences (Beijing) Beijing 100083 China Langfang Branch of China Petroleum Exploration and Development Research Institute Langfang 065007 China PetroChina Coalbed Methane Company Limited Beijing 100076 China Research Institute of Regional Geology and Mineral Resources Shaanxi Bureau of Geological and Mineral Resources Xianyang 712000 China

Based on spontaneous desorption characteristic, the correlation of desorption time and gas content was analyzed and the application of it in production was researched. The desorption of high rank coalbed methane in Qinshui basin was periodic, and isotope fractionation effect also exists in the process. △δ^13C1 can be used to distinguish the stabilization of coalbed methane wells, associated with desorption rate, the individual well recoverable reserves can be calculated. Economically recoverable time can be predicted according to the logarithmic relationship between desorption gas content per ton and desorption time. The error between predicted result and numerical simulation result is only 1.5%.

关键词： coalbed methane desorption isotope discharge recovery reservoir Qinshui basin

基于双近邻模式和最小二乘支持向量机的SAR景象匹配区选择

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宇航学报 2009年第4期30卷 1626-1632页

作者：程华田金文华中科技大学图像识别与人工智能研究所多谱信息处理技术国家重点试验室武汉430074

通过对景象匹配过程的分析,从模式识别的角度阐述了误匹配产生的原因。从避免误匹配的角度定义了双近邻度、最小距离以反映SAR景象的独特性和匹配的准确性,并结合反映地面景物稳定性的边缘密度,构建反映SAR景象适配性的分类特征向量。... 详细信息

通过对景象匹配过程的分析,从模式识别的角度阐述了误匹配产生的原因。从避免误匹配的角度定义了双近邻度、最小距离以反映SAR景象的独特性和匹配的准确性,并结合反映地面景物稳定性的边缘密度,构建反映SAR景象适配性的分类特征向量。基于该分类特征向量,利用最小二乘支持向量机将SAR景象基准图子图划分为匹配正确的子图和匹配错误的子图,并由匹配正确的子图类构成SAR景象适配区。试验结果表明,提出的方法能够有效地规划出所需的SAR景象匹配区。

关键词：匹配区选择双近邻模式最小二乘支持向量机 SAR 景象匹配

Microstructures and mechanical properties of AZ91D/0Cr19Ni9 bimetal composite prepared by liquid-solid compound casting

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Transactions of Nonferrous Metals Society of China 2019年第1期29卷 51-58页

作者： Jian-hua ZHAO wen-qun ZHAO Shen QU Yan-qing ZHANG State Key Laboratory of Mechanical Transmission Chongqing University Chongqing 400044 China College of Materials Science and Engineering Chongqing University Chongqing 400044 China

The liquid-solid compound casting technology was used to produce the AZ91D/0Cr19Ni9 bimetal composite without and with hot dipping aluminium, respectively. The influences of Al coating on microstructures and mechanical properties of AZ91D/0Cr19Ni9 interface were investigated. The results showed that the mechanical bonding was obtained between AZ91D and bare steel 0Cr19Ni9 where a gap existed at the interface; the metallurgical bonding was formed between AZ91D and Al-coated 0Cr19Ni9, which could be divided into two different intermetallic layers: layer Ⅰ was mainly composed of α-Mg+β-Mg17Al12 eutectic structure and a small amount of MgAl2O4, and layer Ⅱ mainly comprised of Fe2Al5 intermetallic compound. Furthermore, the hardness value of interface was obviously higher than that of AZ91D matrix, and the average hardness values of layers Ⅰ and Ⅱ were HV 158 and HV 493, respectively. The shear strength of AZ91D/Al-coated 0Cr19Ni9 interface was higher than that of AZ91D/bare 0Cr19Ni9 interface, which confirmed that Al coating could improve the adhesive strength between AZ91D and 0Cr19Ni9 during liquid-solid compound casting process.

关键词： AZ91D 0Cr19Ni9 liquid-solid compound casting interface bonding shear strength

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地铁列车进出站时土层空间振动特性分析

岩土力学 2019年第9期40卷 3656-3661,3669页

作者：陈文化张谦北京交通大学土木建筑工程学院

地铁列车进、出站引起的土层振动是一种振源特性丰富且复杂的特殊振动。为了研究地铁进、出站时引起土层振动差异性和空间振动特性,首先将地铁进、出站过程中变速移动的振源简化成振动频率、车离站相对位置及行驶位置不断变化的柱面振... 详细信息

地铁列车进、出站引起的土层振动是一种振源特性丰富且复杂的特殊振动。为了研究地铁进、出站时引起土层振动差异性和空间振动特性,首先将地铁进、出站过程中变速移动的振源简化成振动频率、车离站相对位置及行驶位置不断变化的柱面振源。基于波动原理,采用波函数展开法建立空间振源在土层内的波动场表达式;利用反射定律推导不同波型反射波的传播方向,再根据Graf加法公式以及贝塞尔函数的变换特性将波场表达式转换到统一坐标系下,利用大圆弧地表的边界条件求解不同振源位置下的待定波场系数;最后根据频域内振动叠加原理,确立在整个列车进、出站过程中变速移动振源的总波动场。通过比较计算得到的列车进、出站时地表振动频谱和实测地表频谱特性,验证柱面振源的有效性,发现进、出站引起的地表振动低频特性更明显。参数分析表明,启动最大加速度和制动初速度的增加都将使地表竖向振动响应增大。

关键词：地铁地基进、出站变速移动空间振动频谱分析

Four new species and a new record of Orchidinae(Orchidaceae:Orchideae)from China

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Plant Diversity 2021年第5期43卷 390-400页

作者： Dong-Liang Lin Ji-Dong Ya Andre Schuiteman Chong-Bo Ma Cheng Liu Xue-Lian Guo Shi-Si Chen Xi-Long Wang Zhi-Rong Zhang wen-Bin Yu Xiao-hua Jin State Key Laboratory of Systematic and Evolutionary Botany and Herbarium Institute of BotanyChinese Academy of SciencesNanxincun 20XiangshanBeijing100093China Germplasm Bank of Wild Species Kunming Institute of BotanyChinese Academy of SciencesLanhei Road 132HeilongtanKunmingYunnan650201China Herbarium Royal Botanic GardensKewRichmondSurrey TW93ABUK Tibet Plateau Institute of Biology LhasaXizang 850001China University of Chinese Academy of Sciences BeijingChina Center for Integrative Conservation Xishuangbanna Tropical Botanical GardenMengla 666303YunnanChina

Four new species of Orchidaceae from China,Heminium lijiangense,Peristylus fasciculatus,Platanthera milinensis,and Ponerorchis gongshanensis,together with a new country record,Peristylus tenuicallus,are described and illustrated based on morphological and/or phylogenetic *** lijiangense is closely related to *** but differs from it by having the dorsal sepal ovate-orbicular and lip midlobe distinctly shorter than lateral *** is close to Peristylus tradescantifolius but is distinguished from it by having several fascicled and straight,root-like tubers(*** or two oblongoid tubers),old stems usually persistent,middle lobe of lip narrowly ligulate-lanceolate and half as long as the lateral lobes(*** lobe deltoid,about a third as long as the lateral lobes or less),a raised callus at the base of each lateral lobe(*** absent),spur gradually attenuate toward the apex(*** clavate).Platanthera milinensis is similar to *** by sharing small green flowers and lip without a spur,but differs in having a creeping rhizome,a corymbose inflorescence,and a broadly ovate and slightly 3-lobed *** gongshanensis is similar to *** in its small flowers,but differs in having a linear leaf c.3 mm wide(*** 5-13 mm wide),in the lip having collar-like raised margins on the sides of the spur entrance,and a mid-lobe which is notched at the apex but not divided into two divergent lobules that are nearly as large as the lateral lobes,as in *** the proposed species obtained high support in phylogenetic analysis as new *** recently described genus Apetalanthe is reduced to synonymy of Ponerorchis and a new combination is made.

关键词： Orchidaceae Herminium Ponerorchis Peristylus Platanthera China

Effects of allitridi on cell cycle arrest of human gastric cancer cells

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World Journal of Gastroenterology 2005年第35期11卷 5433-5437页

作者： Min-wen Rui Ma Li-Ping Shun Yue-hua Gong Yuan Yuan Cancer Institute of the First Affiliated Hospital of ChinaMedical University Shenyang 110001 Liaoning Province China

AIM： To determine the effect of allitridi on cell cycle of human gastric cancer （HGC） cell lines MGC803 and SGC7901 and its possible mechanism. METHODS： Trypan blue dye exclusion was used to evaluate the proliferation, inhibition of cells and damages of these ceils were detected with electron microscope, Flow cytometry and cell mitotic index were used to analyze the change of cell cycle, immunohistochemistry, and RT- PCR was used to examine expression of the p21^WAF1 gene, RESULTS： MGC803 cell growth was inhibited by allitridi with 24 h ICso being 6.4μg/mL, SGC7901 cell growth was also inhibited by allitridi with 24 h IC50 being 7.3μg/mL, After being treated with allitridi at the concentration of 12μg/mL for 24 h, cells were found to have direct cytotoxic effects, including broken cellular membrane, swollen and vesiculated mitochondria and rough endoplasmic reticula, and mass lipid droplet, When cells were treated with allitridi at the concentration of 3, 6, and 9μg/mL for 24 h, the percentage of Go/G1 phase cells was decreased and that of G2/M phase cells was significantly increased （P = 0.002） compared with those in the group, When cells were treated with allitridi at the concentration of 6μg/mL, cell mitotic index was much higher （P = 0.003） than that of control group, indicating that allitridi could cause gastric cancer cell arrest in M phase, Besides, the expression levels of p21^WAF1 gene of MGC803 cells and p21^WAF1 gene of SGC7901 cells were remarkably upregulated after treatment, CONCLUSION： Allitridi can cause gastric cancer cell arrest in M phase, and this may be one of the mechanisms for inhibiting cell proliferation, Effect of allitridi on cells in M phase may be associated with the upregulation of p21^WAF1 genes. This study provides experimental data for clinical use of allitridi in the treatment of gastric carcinoma.

关键词： Allitridi Gastric cancer cells Cell cycle p21^WAF1

Withaferin A inhibits ferroptosis and protects against intracerebral hemorrhage

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Neural Regeneration Research 2023年第6期18卷 1308-1315页

作者： Zi-Xian Zhou Qi Cui Ying-Mei Zhang Jia-Xin Yang wen-Jing Xiang Ning Tian Yan-Lin Jiang Mei-Ling Chen Bin Yang Qing-hua Li Ru-Jia Liao Laboratory of Neuroscience Affiliated Hospital of Guilin Medical UniversityGuilin Medical UniversityGuilinGuangxi Zhuang Autonomous RegionChina Department of Neurology Affiliated Hospital of Guilin Medical UniversityGuilin Medical UniversityGuilinGuangxi Zhuang Autonomous RegionChina Guangxi Clinical Research Center for Neurological Diseases Affiliated Hospital of Guilin Medical UniversityGuilin Medical UniversityGuilinGuangxi Zhuang Autonomous RegionChina Department of Pharmacology Affiliated Hospital of Guilin Medical UniversityGuilin Medical UniversityGuilinGuangxi Zhuang Autonomous RegionChina

Recent studies have indicated that suppressing oxidative stress and ferroptosis can considerably improve the prognosis of intracerebral hemorrhage(ICH).Withaferin A(WFA),a natural compound,exhibits a positive effect on a number of neurological ***,the effects of WFA on oxidative stress and ferroptosis-mediated signaling pathways to ICH remain *** this study,we investigated the neuroprotective effects and underlying mechanism for WFA in the regulation of ICH-induced oxidative stress and *** established a mouse model of ICH by injection of autologous tail artery blood into the caudate nucleus and an in vitro cell model of hemin-induced *** was injected intracerebroventricularly at 0.1,1 or 5μg/kg once daily for 7 days,starting immediately after ICH *** markedly reduced brain tissue injury and iron deposition and improved neurological function in a dose-dependent manner 7 days after cerebral *** in vitro experiments,cell viability test showed that WFA protected SH-SY5Y neuronal cells against hemin-induced cell ***-linked immunosorbent assays in vitro and in vivo showed that WFA markedly decreased the level of malondialdehyde,an oxidative stress marker,and increased the activities of anti-oxidative stress markers superoxide dismutase and glutathione peroxidase after *** blot assay,quantitative polymerase chain reaction and immunofluorescence results demonstrated that WFA activated the nuclear factor E2-related factor 2(Nrf2)/heme oxygenase-1(HO-1)signaling axis,promoted translocation of Nrf2 from the cytoplasm to nucleus,and increased HO-1 *** Nrf2 with siRNA completely reversed HO-1 expression,oxidative stress and protective effects of ***,WFA reduced hemin-induced ***,after treatment with an HO-1 inhibitor,the neuroprotective effects of WFA against hemin-induced ferroptosis were *** test results showed that WFA combined with ferrostatin-1

关键词： behavior brain injuries hemorrhagic stroke ferroptosis heme oxygenase-1 neuroprotection nuclear factor E2-related factor 2 nuclear translocator oxidative stress stroke