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International Journal of Minerals,Metallurgy and Materials 2021年第11期28卷 1769-1776页

作者： Fei Cao Wei Wang De-zhou Wei wen-gang liu School of Resource and Civil Engineering Northeastern UniversityShenyang 110819China Zhengzhou Institute of Multipurpose Utilization of Mineral Resources CAGSZhengzhou 450006China Key Laboratory for Polymetallic Ores’Evaluation and Utilization MNRZhengzhou 450006China

Functionalized ionic liquids(FILs)as extractants were employed for the separation of tungsten and molybdenum from a sulfate solution for the first *** effects of initial pH,extractant concentration,metal concentrations in the feed were comprehensively *** results showed that tricaprylmethylammonium bis(2,4,4-trimethylpentyl)phosphinate([A336][Cyanex272])could selectively extract W over Mo at an initial pH value of 5.5;the best separation factorβ_(W/Mo) of 25.61 was obtained for a solution with low metal concentrations(WO3:2.49 g/L,Mo:1.04 g/L).The[A336][Cyanex272]system performed effectively for solutions of different W/Mo molar ratios and different metal ion concentrations in the *** chemical reaction between[A336][Cyanex272]and W followed the ion association mechanism,which was further proved by the Fourier-transform infrared(FTIR)spectra of loaded[A336][Cyanex272]and the free *** stripping experiments indicated that 95.48%W and 100.00%Mo were stripped using a 0.20 mol/L sodium hydroxide ***,the selective extractions of W and Mo from two synthetic solutions of different high metal concentrations were obtained;the separation factorβW/Mo reached 23.24 and 17.59 for the first and second solutions,*** results suggest the feasibility of[A336][Cyanex272]as an extractant for the separation of tungsten and molybdenum.

关键词： tungsten molybdenum ionic liquid separation solvent extraction

Design and comparison of hybrid multi-bend achromat lattices for HALF storage ring

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Nuclear Science and Techniques 2023年第7期34卷 189-197页

作者： Peng-Hui Yang gang-wen liu Jian-Hao Xu Wei-Wei Li Tian-Long He Zheng-He Bai National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China

The Hefei Advanced Light Facility(HALF)proposed by the National Synchrotron Radiation Laboratory is a green-field vacuum ultraviolet and soft X-ray diffraction-limited storage ring light source with a beam energy of 2.2 GeV and emittance goal of less than 100 pm *** by the ESRF-EBS hybrid multi-bend achromat(HMBA),SLS-2,and Diamond-II lattices,we have proposed and designed a modified H6BA lattice as the baseline lattice of the HALF storage ring with 20 identical cells and a natural emittance of approximately 86 pm *** this paper,three other types of HMBA lattices including two H7BA lattices and a H6BA lattice are designed for HALF with the same number of *** main storage ring proper-ties of these four HMBA lattices are *** the intra-beam scattering(IBS)effect is significant in the HALF storage ring,we calculate and compare the equilibrium emittances of the four lattices with IBS *** comparisons show that the present modified H6BA lattice,which has a relatively low equilibrium emittance and more straight sections,is preferred for the HALF storage ring after a comprehensive consideration.

关键词： Hefei advanced light facility Lattice design Hybrid MBA lattice Intra-beam scattering

Density Functional Theory Study of Selectivity of Crown Ethers to Li^+ in Spent Lithium-Ion Batteries Leaching Solutions

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Chinese Journal of Chemical Physics 2019年第3期32卷 343-348,I0002页

作者： Yong-lin Yao Mei-ying Zhu Zhuo Zhao wen-gang liu Bi-hai Tong Ming-yang Li School of Metallurgical Engineering Anhui University of TechnologyMaanshan 243002China School of Resources and Civil Engineering Northeastern UniversityShenyang 110819China Key Laboratory of Metallurgical Emission Reduction & Resources Recycling Anhui University of TechnologyMaanshan 243002China

It is a challenge to recover lithium from the leaching solution of spent lithium-ion batteries,and crown ethers are potential extractants due to their selectivity to alkali metal *** theoretical calculations for the selectivity of crown ethers with different structures to Li ions in aqueous solutions were carried out based on the density functional *** calculated results of geometries,binding energies,and thermodynamic parameters show that 15C5 has the strongest selectivity to Li ions in the three crown ethers of 12C4,15C5,and 18C6.B15C5 has a smaller binding energy but more negative free energy than 15C5 when combined with Li^+,leading to that the lithium ions in aqueous solutions will combine with B15C5 rather than *** exchange reactions between B15C5 and hydrated Li^+,Co^2+,and Ni^2+were analyzed and the results show that B15C5 is more likely to capture Li^+from the hydrated ions in an aqueous solution containing Li^+,Co^2+,and Ni^2+.This study indicates that it is feasible to extract Li ions selectively using B15C5 as an extractant from the leaching solution of spent lithium-ion batteries.

关键词： Density functional theory Crown ether Geometry Binding energy Thermodynamic parameter

VIRTUAL INSTRUMENT AND FREQUENCY CONVERSION TECHNOLOGY-BASED BRAKE TEST SYSTEM

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VIRTUAL INSTRUMENT AND FREQUENCY CONVERSION TECHNOLOGY-BASED...

2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： MENG wenjun, wen Hao, HAN gang, liu Weili Taiyuan University of Science & Technology, Taiyuan 030024, China

Brake is widely useful and very important safety assuring equipment. The aim of Brake test system, which is based on visual instrument and frequency changing technology, is to integrative measure and

关键词： Brake visual instrument frequency changing test and control.

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砂带三维表面形貌特征量化评价方法

华南理工大学学报（自然科学版） 2016年第12期44卷 14-22页

作者：王文玺李建勇樊文刚刘月明北京交通大学机械与电子控制工程学院北京100044

为实现对砂带三维表面形貌特征的量化评价，针对砂带表面磨粒外形、尺寸、分布均具有强不规则性与随机性的特点，提出一种包含功率谱密度分析、自相关函数分析和磨粒特征统计学分析的评价方法，通过获得砂带表面截止频率、自相关长度、... 详细信息

为实现对砂带三维表面形貌特征的量化评价，针对砂带表面磨粒外形、尺寸、分布均具有强不规则性与随机性的特点，提出一种包含功率谱密度分析、自相关函数分析和磨粒特征统计学分析的评价方法，通过获得砂带表面截止频率、自相关长度、纹理横纵比、磨粒密度、磨粒出刃高度、磨粒间距、磨粒刃端半径及顶锥角等评价参数，从宏观整体到局部磨粒对表面形貌特征完成定性和定量评价．以P60、P80、P100和P120号粒度锆刚玉砂带为例进行试验，结果表明：砂带表面呈各向同性，随粒度号增加砂带表面自相关程度降低；磨粒密度增加，磨粒等高性与位置分布均匀性加强；刃端半径减小，顶锥角保持在70°-85°；表面磨粒间距与磨粒出刃高度均近似服从正态分布．

关键词：砂带表面形貌量化评价磨粒出刃高度磨粒间距

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： wen Gao Jing-wen Li Hui Ye Xue-Zhi Zhang Jian-Xiang liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

基于UML的飞行器动力学虚拟样机仿真建模研究

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系统仿真学报 2004年第2期16卷 231-233页

作者：贾荣珍张文苑刘刚北京航空航天大学先进仿真技术航空科技重点实验室北京100083

建模是虚拟样机系统的基础。本文论述了飞行器动力学虚拟样机系统飞行系统仿真模型库的组成和功能,并且应用可视化面向对象建模技术明确划分导弹飞行仿真模型库类库,应用标准建模语言UML(Unified Modeling Language)设计飞行仿真模型库... 详细信息

建模是虚拟样机系统的基础。本文论述了飞行器动力学虚拟样机系统飞行系统仿真模型库的组成和功能,并且应用可视化面向对象建模技术明确划分导弹飞行仿真模型库类库,应用标准建模语言UML(Unified Modeling Language)设计飞行仿真模型库的用例图、活动图、类图,提高了飞行仿真模型库的可重用性,并用于导弹动力学虚拟样机的研究。

关键词：虚拟样机仿真建模模型库标准建模语言(UML)

PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong liu Xiaolin Li Xiaowei Zhou Wei Chen Aidong wen Minna liu Yi Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics

Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu Yue Li Hua Zhang Lian-Lian Wang wen-wen liu Xin Yang Ming-Zhao Xiao Hao-Ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

Selective depression of galena and chalcopyrite by O,O-bis(2,3-dihydroxypropyl) dithiophosphate

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Transactions of Nonferrous Metals Society of China 2013年第10期23卷 3063-3067页

作者：朴正杰魏德洲刘智林刘文刚高淑玲李明阳东北大学资源与土木工程学院沈阳110004 江西理工大学资源与环境学院赣州341000

A novel synthesized reagent, O,O-bis（2,3-dihydroxypropyl） dithiophosphate （DHDTP）, was investigated as depressant on the depression of chalcopyrite and galena, when ammonium dibutyl dithiophosphate （DDTP） was used as the collector in flotation tests. Zeta potential and adsorption measurement were performed to study the interaction between depressant and minerals. The flotation tests of two minerals show that DHDTP has slight depression on chalcopyrite in the whole pH range and strong depression on galena in the pH range of 6-10. When DHDTP dosage is increased, the recovery of galena decreases rapidly, while that of the chalcopyrite decreases slightly. The satisfied separation results of artificially mixed samples are that the copper grade and recovery rates of concentrate are 24.08% and 81%, respectively, when the pH is 6 with 278 mg/L DHDTP. Zeta potential and adsorption measurements show that DHDTP has more strongly adsorotion capacity to galena than chalcoovrite.

关键词： O,O-bis(2,3-dihydroxypropyl) dithiophosphate flotation chalcopyrite galena depressant