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Crosslinking Kinetics of Polyethylene with Small Amount of Peroxide and Its Influence on the Subsequent Crystallization Behaviors

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Chinese Journal of Polymer Science 2016年第9期34卷 1117-1128页

作者：牛艳华 wen-bin liang Yin-ling Zhang Xue-lian Chen Shih-yaw Lai Guang-xian Li Du-jin Wang College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering of ChinaSichuan UniversityChengdu 610065China Performance Material Center National Institute of Clean-and-low-carbon Energy(NICE)Beijing 102209China CAS Key Laboratory of Engineering Plastics Beijing National Laboratory for Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China

Crosslinking reactions of high density polyethylene with low peroxide concentrations ranging from 0.1 wt% to 1.0 wt% at temperatures of 170, 180 and 190 ℃ were monitored by rheological measurements. A critical gel forms at the peroxide concentration of 0.2 wt%, where the transition from long chain branching generation to crosslinking network formation could occur. Rheokinetics of crosslinking can be fitted well by Ding-Leonov＇s model. The curing rate k2 at the earlier stage exhibits about 3 times acceleration per 10 ~C with increasing temperature, while the equilibrium modulus G＇ at the fully cured stage is almost independent of temperature. Influences of crosslinking on the subsequent crystallization behaviors were detected by DSC measurements. Above the critical gel concentration, crystallization is largely retarded as evidenced by the lower crystallization temperature Tc and crystallinity Xc due to the network formation. The secondary crystallization valley located at the temperature near 80 ℃ can be observed above the critical concentration, which becomes more evident with the increasing peroxide concentration and curing temperature. This phenomenon provides another evidence of crystallization retardation by the crosslinking network.

关键词： Polyethylene Rheology Crosslinking kinetics Crystallization.

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Macrophage-NLRP3 Inflammasome Activation Exacerbates Cardiac Dysfunction after Ischemic Stroke in a Mouse Model of Diabetes

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Neuroscience Bulletin 2020年第9期36卷 1035-1045页

作者： Hong-bin Lin Guan-Shan Wei Feng-Xian Li wen-Jing Guo Pu Hong Ya-Qian weng Qian-Qian Zhang Shi-Yuan Xu wen-bin liang Zhi-Jian You Hong-Fei Zhang Department of Anesthesiology Zhujiang Hospital of Southern Medical UniversityGuangzhou 510220China Department of Anesthesiology Shenzhen SAMII Medical CenterShenzhen 518118China Department of Anesthesiology The Second Affiliated HospitalShantou University Medical CollegeShantou 515041China University of Ottawa Heart Institute and Department of Cellular and Molecular Medicine University of OttawaOntarioK1NCanada

Ischemic stroke is one of the leading causes of death *** the post-stroke stage,cardiac dysfunction is common and is known as the brain-heart *** mellitus worsens the post-stroke ***-induced systemic inflammation is the major causative factor for the sequential complications,but the mechanism underlying the brain-heart interaction in diabetes has not been *** NLRP3(NLR pyrin domain-containing 3) inflammasome,an important component of the inflammation after stroke,is mainly activated in M1-polarized *** this study,we found that the cardiac dysfunction induced by ischemic stroke is more severe in a mouse model of type 2 ***,M1-polarized macrophage infiltration and NLRP3 inflammasome activation increased in the cardiac ventricle after diabetic ***,the NLRP3 inflammasome inhibitor CY-09 restored cardiac function,indicating that the Ml-polarized macrophage-NLRP3 inflammasome activation is a pathway underlying the brain-heart interaction after diabetic stroke.

关键词： Ischemic stroke Diabetes mellitus Cardiac dysfunction NLRP3 inflammasome Macrophage

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Cerebral perfusion in patients with unilateral internal carotid artery occlusion by dual post-labeling delays arterial spin labeling imaging

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World Journal of Radiology 2024年第9期16卷 429-438页

作者： Gui-Rong Zhang Yan-Yan Zhang wen-bin liang Dun Ding Department of Medical Imaging The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710043Shaanxi ProvinceChina

BACKGROUND Global and regional cerebral blood flow(CBF)changes in patients with unilateral internal carotid artery occlusion(ICAO)are unclear when the dual post-labeling delays(PLD)arterial spin labeling(ASL)magnetic resonance imaging(MRI)technique is *** delineation of regions of interest for CBF measurement is time-consuming and *** To assess global and regional CBF changes in patients with unilateral ICAO with the ASL-MRI perfusion *** Twenty hospitalized patients with ICAO and sex-and age-matched controls were included in the *** CBF was measured by ***'s ASL *** present study evaluated differences in global,middle cerebral artery(MCA)territory,anterior cerebral artery territory,and Alberta Stroke Program Early Computed Tomography Score(ASPECTS)regions(including the caudate nucleus,lentiform nucleus,insula ribbon,internal capsule,and M1-M6)and brain lobes(including frontal,parietal,temporal,and insular lobes)between ICAO patients and controls at PLD 1.5 s and PLD 2.5 *** When comparing CBF between ICAO patients and controls,the global CBF in ICAO patients was lower at both PLD 1.5 s and PLD 2.5 s;the CBF on the occluded side was lower in 15 brain regions at PLD 1.5 s,and it was lower in 9 brain regions at PLD 2.5 s;the CBF in the contralateral hemisphere was lower in the caudate nucleus and internal capsule at PLD 1.5 s and in M6 at PLD 2.5 *** global CBF in ICAO patients was lower at PLD 1.5 s than at PLD 2.5 *** ipsilateral CBF at PLD 1.5 s was lower than that at PLD 2.5 s in 15 regions,whereas the contralateral CBF was lower at PLD 1.5 s than at PLD 2.5 s in 12 *** ipsilateral CBF was lower than the contralateral CBF in 15 regions at PLD 1.5 s,and in M6 at PLD 2.5 *** Unilateral ICAO results in hypoperfusion in the global and MCA territories,especially in the ASPECTS *** PLD settings prove more suitable for accurate CBF quantification in ICAO.

关键词： Arterial spin labeling Internal carotid artery occlusion Ischemic stroke Cerebral blood flow Hemodynamic

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一种利用补丁的未知漏洞发现方法

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软件学报 2018年第5期29卷 1199-1212页

作者：李赞边攀石文昌梁彬中国人民大学信息学院北京100872

近年来,利用含有已知漏洞的函数作为准则,通过查找相似代码实现来检测未知漏洞的方法已被证明是有效的.但是,一个含有漏洞的函数通常也包含一些与已知漏洞无关的语句,严重影响相似度计算的结果,从而引发误报和漏报.提出了一种利用补丁... 详细信息

近年来,利用含有已知漏洞的函数作为准则,通过查找相似代码实现来检测未知漏洞的方法已被证明是有效的.但是,一个含有漏洞的函数通常也包含一些与已知漏洞无关的语句,严重影响相似度计算的结果,从而引发误报和漏报.提出了一种利用补丁来提高这种相似性检测准确性的漏洞发现方法.结合漏洞的补丁信息,引入程序切片技术去除原来含有漏洞的函数中与漏洞无关的语句,利用获得的切片生成去噪的漏洞特征来进行潜在未知漏洞检测.该方法已经在一些真实的代码集中实施,并且实验结果证明该方法确实能够有效减弱漏洞无关语句的干扰,达到提高检测准确性的目的.该方法还成功检测到了3个未知漏洞且已经得到确认.

关键词：漏洞补丁切片相似性检测

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ECL金属-有机框架(MOF)生物传感平台用于肿瘤细胞分泌H_(2)O_(2)的测定

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化学学报 2021年第10期79卷 1257-1264页

作者：廖妮钟霞梁文斌袁若卓颖西南大学化学化工学院发光分析与分子传感教育部重点实验室重庆400715 攀枝花学院生物与化学工程学院攀枝花617000

本工作借助金属-有机框架(MOF)结构,通过配位作用实现对电化学发光(ECL)分子的空间有序组装,获得了高性能ECL新材料,发展了孔道限域效应和微纳空间ECL分子有序组装的协同增强ECL新策略.具体而言,以非共平面ECL分子1,1,2,2-四(4-羧基苯)... 详细信息

本工作借助金属-有机框架(MOF)结构,通过配位作用实现对电化学发光(ECL)分子的空间有序组装,获得了高性能ECL新材料,发展了孔道限域效应和微纳空间ECL分子有序组装的协同增强ECL新策略.具体而言,以非共平面ECL分子1,1,2,2-四(4-羧基苯)乙烯(H4TCPE)为配体采用一步水热法合成了具有优异ECL性能的新型MOF材料(Zr-TCPE).Zr-TCPE通过将发光配体H4TCPE固定在MOF多孔材料上,一方面其多孔结构可以促进限域空间内物质和电子的传递,加快电化学反应的效率;同时,MOF结构的配位键合作用限制了发光基团的自由转动与振动以及分子间的紧密堆积,从而有效减少了非辐射弛豫和内滤效应.和H4TCPE的微纳晶体相比,Zr-TCPE的ECL强度提高了3.46倍,ECL效率提高了17.44倍.采用Zr-TCPE构建了ECL生物传感平台,成功实现了在药物刺激下肿瘤细胞释放过氧化氢(H_(2)O_(2))的原位监测,对临床检测肿瘤细胞具有指导意义.

关键词：金属-有机框架材料 1 1 2 2-四(4-羧基苯)乙烯电化学发光生物传感器肿瘤细胞过氧化氢

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Analysis on the Effect of Acupuncture in Treating Cervical Spondylosis with Different Syndrome Types

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Chinese Journal of Integrative Medicine 2009年第6期15卷 426-430页

作者：符文彬梁兆晖朱晓平于鹏张继福 Acupuncture and Moxibustion Department of Guangdong Provincial Hospital of Traditional Chinese Medical Sciences Guangdong Provincial Academy of Chinese Medicinal Sciences

Objective:To observe the clinical effect of acupuncture in treating cervical spondylosis with different syndrome ***:One hundred and seventeen patients were randomized into the treated group (59 cases),treated with normal acupuncture,and the control group(58 cases),treated with sham acupuncture, operated once every other day,9 times in total(in 18 days) as one therapeutic course,and a succeeding 3-month follow-up study was carried out after terminating the *** efficacy of treatment was eva...

关键词： acupuncture cervical spondylosis efficacy evaluation repeated measurement

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一种基于规则推理的BDI模型实现

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计算机科学 2003年第5期30卷 30-32页

作者：唐文彬朱淼良浙江大学人工智能研究所杭州310027

The common idea is to consider agents whose mental state comprises the three attitudes of belief、desire andintention. The relationships among these entities have received considerable attention. There still remains a large gapbetween theory and practice. In this paper, the authors implement a BDI agent system based on rule reasoning andshow the procedure of planning. The experiment shows the system can handle application problem.

关键词： BDI模型规则推理人工智能黑板系统规则库

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基于强化学习的多Agent系统

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计算机科学 2003年第4期30卷 16-18页

作者：唐文彬朱淼良浙江大学人工智能研究所杭州310027

Reinforcement learning allows agent that has no knowledge of an environment to cooperate more efficacious each other. This paper presents an approach for developing multi-agent reinforcement learning systems based on ... 详细信息

关键词：多Agent系统人工智能强化学习学习算法

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一类Duffing型p-Laplacian平均曲率方程周期解

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烟台大学学报（自然科学与工程版） 2016年第4期29卷 244-251页

作者：陈文斌董良武夷学院数学与计算机学院福建武夷山354300

考虑了一类Duffing型p-Laplacian平均曲率方程周期解存在性问题.通过运用Mawhin重合度拓展定理和一些积分分析技巧,获得了此类平均曲率方程至少存在一个T-周期解.一个具体的数值例子充分说明了本文方法与结论的有效性.此外,用Matlab画... 详细信息

考虑了一类Duffing型p-Laplacian平均曲率方程周期解存在性问题.通过运用Mawhin重合度拓展定理和一些积分分析技巧,获得了此类平均曲率方程至少存在一个T-周期解.一个具体的数值例子充分说明了本文方法与结论的有效性.此外,用Matlab画出了其数值解图.

关键词：周期解平均曲率重合度定理 Duffing型 p-Laplacian方程

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A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： Xiao liang Xingping Quan Xiaorui Geng Yujing Huang Yonghua Zhao Lei Xi Zhen Yuan Ping Wang bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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