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USING OF MULTISLICE HELICAL CT COLONOGRAPHY IN PATIENTS WITH MALIGNANT LESIONS OF COLON

Chinese Medical Sciences Journal 2005年第3期20卷 171-175页

作者： Ming-wei Qin Wei-dong Pan Guan-ning Cong Yun Wang Yun-qing Zhang wen-bin mou Zheng-yu Jin Department of Radiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objoctive To investigate the techniques and clinical applications ofmultislice helical computed tomography （CT） colonography in colonic lesions. Methods Fifty-nine patients with malignant lesions of colon underwent volume scanning using multislice helical CT. Four types of reconstruction including CT virtual colonoscopy （CTVC）, shaded surface display （SSD）, Raysum, and multiple planar reconstruction （MPR） were used for image post-processing. The results were compared with those of colonoscopy and pathology. Results Multislice helical CT colonography detected 54 colorectal carcinomas, 4 adenomas with focal carcinoma, 1 non-Hodgkin＇s lymphoma （NHL）. The lesions＇ number, size, location, morphology, stricture of intestinal cavity, infiltration, and metastasis were shown satisfactorily by multislice helical CT colonography. Whole colon could be shown in all patients. CT colonography displayed 4 synchronous colonic tumors, 1 ascending colon carcinoma combined with left renal carcinoma among 54 patients with colonic carcinomas. The accuracy of location of CT colonography was 100%. There were 9 cases that CT showed the tumor location was different from the finding of conventional colonoscopy, while all of the CT location were proven exact by operation. CT colonography also displayed the infiltration of serous layer and fatty tissue in 45 cases; 21 cases matched the pathological results in all the 24 cases of suspicious lymph node metastasis, the sensitivity was 87.5%, the specificity was 90.6%; 9 cases hepatic metastasis, 2 ovarian metastasis, and 1 double adrenal gland metastasis. Conclusions Multislice helical CT colonography is effective in preoperative diagnosis, location, stage, and making treatment plan of colorectal carcinoma. It can display the portion not seen during colonoscopy and may have an adjunctive role.

关键词： tomography, X-ray computed colorectal neoplasms image processing, computer assisted

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CORONARY ANGIOGRAPHY WITH DUAL SOURCE COMPUTED TOMOGRAPHY:INITIAL EXPERIENCE

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Chinese Medical Sciences Journal 2007年第4期22卷 205-210页

作者： Zhu-hua Zhang Zheng-yu Jin Shu-yang Zhang Song-bai Lin Dong-jing Li Ling-yan Kong Yi-ning Wang Lan Song Yun Wang wen-min Zhao wen-bin mou Li-ren Zhang wen-ling Zhu Qi Miao Qi Fang Department of Radiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Department of Cardiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Special Medical Care Center Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Department of Cardiac Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objective To explore the scan technique and image quality of coronary angiography with dual source computed tomography(CT) without oral metoprolol *** Plain and enhanced dual source CT coronary angiography without oral metoprolol preparation was prospectively performed in 600 *** scoring with plain scan images as well as multi-planar reconstruction(MPR),maximum intensity projection(MIP),and volume rendering technique(VRT) reconstruction with enhanced scan images were performed in all *** scan technique and post-reconstruction experience was *** image quality was classified as 1 to 4 points,and coronary segments classified according to the American Heart Association standards were *** The average calcium score of the 600 cases was 213.6±298.7(0-3 216.5).The average heart rate of the enhanced scan was 82.1±16.2(47-139) *** post-reconstruction methods with which coronary segments could be shown as best as possible consisted of single phase reconstruction method,two or more phases supplemented method,and electrocardiogram editing *** 8 457 coronary segments were evaluated,among which 97.2% were evaluated as point 1,1.7% point 2,0.5% point 3,and 0.6% point *** coronary segments in 261 cases were completely normal,while 360 segments were diagnosed with <50% stenosis and 625 segments with ≥50% *** Excellent coronary artery image can be obtained with dual source CT in patients with any heart rate without oral metoprolol *** rate is not a major source of the artifact,coronary segments can be well shown with single or multiple-phase reconstruction method.

关键词： computed tomography coronary angiography coronary heart disease

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流行度划分结合平均偏好权重的协同过滤个性化推荐算法

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计算机科学 2018年第B06期45卷 493-496页

作者：何佶星陈汶滨牟斌皓西南石油大学计算机科学学院成都610500

提出了一种考虑平均偏好权重的协同过滤个性化推荐算法。该算法分为邻域计算、数据集划分、偏好预测3个阶段。在邻域计算阶段,采用基于欧氏距离的KNN来确定邻域;同时对数据集按照其本身特点设定的流行度阈值进行划分;在预测评分时,对已... 详细信息

提出了一种考虑平均偏好权重的协同过滤个性化推荐算法。该算法分为邻域计算、数据集划分、偏好预测3个阶段。在邻域计算阶段,采用基于欧氏距离的KNN来确定邻域;同时对数据集按照其本身特点设定的流行度阈值进行划分;在预测评分时,对已有的邻域按照流行度选取部分项目,基于项目集的偏好相似度求解用户的平均偏好权重,据此对用户进行先后两次预测,再求平均结果。在Movielens 100K数据集上将所提算法与典型的余弦推荐算法、person推荐算法、基于项目偏好的协调过滤算法和用户属性加权活跃近邻的协同过滤算法进行比较实验,结果表明新算法在MAE上表现的更优秀。

关键词：协同过滤 KNN 个性化推荐算法流行度划分平均偏好权重邻域计算

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Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： mou Gao Qin Dong Dan Zou Zhijun Yang Lili Guo Ruxiang Xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurosurgery Chinese PLA General HospitalBeijingChina Department of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and *** previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in induced neural stem cells remains *** this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial *** agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury ***,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head *** conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neura

关键词： Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell microglia neuroinflammation

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Robust bounded control for uncertain flight dynamics using disturbance observer

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Journal of Systems Engineering and Electronics 2014年第4期25卷 640-647页

作者： mou Chen bin Jiang College of Automation Engineering Nanjing University of Aeronautics and Astronautics

The robust bounded flight control scheme is developed for the uncertain longitudinal flight dynamics of the fighter with control input saturation invoking the backstepping technique. To enhance the disturbance rejection ability of the robust flight control for fighters, the sliding mode disturbance observer is designed to estimate the compounded disturbance including the unknown external disturbance and the effect of the control input saturation. Based on the backstepping technique and the compounded disturbance estimated output, the robust bounded flight control scheme is proposed for the fighter with the unknown external disturbance and the control input saturation. The closed-loop system stability under the developed robust bounded flight control scheme is rigorously proved using the Lyapunov method and the uniformly asymptotical convergences of all closed-loop signals are guaranteed. Finally, simulation results are presented to show the effectiveness of the proposed robust bounded flight control scheme for the uncertain longitudinal flight dynamics of the fighter.

关键词： flight dynamics bounded control robust control backstepping control disturbance observer.

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Improvements for matrix-type implicit temporal scheme regarding entropy fix and local time step

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Chinese Journal of Aeronautics 2024年第11期37卷 138-146页

作者： Jian LIU Jianqiang CHEN Yufeng YANG bin mou State Key Laboratory of Aerodynamics Mianyang 621000China China Aerodynamics Research and Development Center Mianyang 621000China

The matrix version of Symmetric Successive Over Relaxation(matrix-SSOR)scheme has been proved to be more efficient than the standard Lower-Upper Symmetric Gauss-Seidel(LUSGS),but less robust for high-speed *** order to ulteriorly improve the convergence rate as well as numerical stability of matrix-SSOR,two improvements regarding entropy fix and local time step have been proposed and ***,an augmented entropy fix method is imposed on the inviscid Jacobian matrix and proved to be effective in two high-speed flows,in which the key parameter in entropy fix is discussed and found to be insensitive within appropriate range of *** the time step also has great effects on the numerical stability and convergence rate,a modified cell residual adapted local time step method with consideration of the residual history is developed,which is found to be effective for increasing the convergence rate when the matrix-SSOR is applied,but invalid when the LU-SGS is *** proposed modified local time step method is also insensitive to the key parameter within appropriate range of *** two modifications can be conveniently implanted into analogous matrix-type implicit schemes to improve the numerical performance.

关键词： Computational fluid dynamics LU-SGS Matrix-SSOR Entropy fix Local time step Residual

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Guaranteed transient performance based control with input saturation for near space vehicles

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Science China(Information Sciences) 2014年第5期57卷 260-271页

作者： CHEN mou WU QinXian JIANG ChangSheng JIANG bin College of Automation Engineering Nanjing University of Aeronautics and Astronautics

This paper describes the design of guaranteed transient performance based attitude control for the near space vehicle(NSV)with control input saturation using the backstepping *** improve the robust controllability of the NSV,the parameter adaptive method is used to tackle the integrated effect of unknown time-varying disturbance and control input *** on the backstepping technique and parameter estimated outputs,a robust attitude control scheme is proposed for the NSV with input saturation.A novel robust attitude control scheme is then proposed based on a prescribed performance bound(PPB)which characterizes the convergence rate and maximum overshoot of the attitude tracking *** closed-loop system stability under both the developed robust attitude control schemes is proved using Lyapunov’s method and uniformly asymptotical convergence of all closed-loop signals is ***,simulation results are given to show the effectiveness of both the proposed robust constrained attitude control schemes.

关键词： near space vehicles prescribed performance robust attitude control backstepping control input saturation

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盐边县温泉井田煤质特征及用途评价

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煤炭技术 2025年第1期44卷 120-124页

作者：牟文阳伟唐晓林四川省能源地质调查研究所成都610072

盐边县温泉井田的地质勘查程度已经不能满足中型矿井开采的可行性研究,因此,需要对该地区的煤质特征及工艺性能进行进一步研究。温泉井田主要含煤地层为上三叠统大荞地组,煤层结构简单,共含可采煤层7层(全区可采3层,局部可采4层),各煤... 详细信息

盐边县温泉井田的地质勘查程度已经不能满足中型矿井开采的可行性研究,因此,需要对该地区的煤质特征及工艺性能进行进一步研究。温泉井田主要含煤地层为上三叠统大荞地组,煤层结构简单,共含可采煤层7层(全区可采3层,局部可采4层),各煤层平均厚度0.41~0.83 m。宏观煤岩组分以半暗煤为主,次为半亮煤;多呈不规则的细-中条带状、线理状产出。显微组分以镜质组为主,有机显微组分含量较高,灰分变化大,硫分、水分低、浮煤挥发分含量高,发热量大;流动温度、软化温度均以中等程度为主,煤灰成分主要为SiO_(2)、Al_(2)O_(3)和Fe_(2)O_(3),煤对二氧化碳的反应性与温度呈正相关,而煤灰黏度与温度呈负相关。因此,综合认为温泉井田主要可采煤层属低-中灰、特低硫-低硫、中高-高发热量的煤,主要利用方向可作为优质炼焦配煤,用于生产冶金焦炭。

关键词：盐边县井田煤质特征优质炼焦配煤

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Soil Carbon, Nitrogen and Phosphorus Concentrations and Stoichiometries Across a Chronosequence of Restored Inland Soda Saline-Alkali Wetlands, Western Songnen Plain, Northeast China

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Chinese Geographical Science 2020年第5期30卷 934-946页

作者： YANG Yanli mou Xiaojie wen Bolong LIU Xingtu Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and AgroecologyChinese Academy of Sci-encesChangchun 130102China University of Chinese Academy of Sciences Bejjing 100049China

Soil carbon(C), nitrogen(N) and phosphorus(P) concentrations and stoichiometries can be used to evaluate the success indicators to the effects of wetland restoration and reflect ecosystem function. Restoration of inland soda saline-alkali wetlands is widespread, however, the soil nutrition changes that follow restoration are unclear. We quantified the recovery trajectories of soil physicochemical properties, including soil organic carbon(SOC), total nitrogen(TN), and total phosphorus(TP) pools, for a chronosequence of three restored wetlands(7 yr, 12 yr and 21 yr) and compared these properties to those of degraded and natural wetlands in the western Songnen Plain, Northeast China. Wetland degradation lead to the loss of soil nutrients. Relative to natural wetlands, the mean reductions of in SOC, TN, and TP concentrations were 89.6%, 65.5% and 52.5%, respectively. Nutrients recovered as years passed after restoration. The SOC, TN, and TP concentrations increased by 2.36 times, 1.15 times, and 0.83 times, respectively in degraded wetlands that had been restored for 21 yr, but remained 29.2%, 17.3%, and 12.8% lower, respectively, than those in natural wetlands. The soil C∶N(RC N), C∶P(R CP), and N∶P(R NP) ratios increased from 5.92 to 8.81, 45.36 to 79.19, and 7.67 to 8.71, respectively in the wetland that had been restored for 12 yr. These results were similar to those from the natural wetland and the wetland that had been restored for 21 yr(P > 0.05). Soil nutrients changes occurred mainly in the upper layers(≤ 30 cm), and no significant differences were found in deeper soils(> 30 cm). Based on this, we inferred that it would take at least 34 yr for SOC, TN, and TP concentrations and 12 yr for RC N, R CP, and RN P in the top soils of degraded wetlands to recover to levels of natural wetlands. Soil salinity negatively influenced SOC(r =-0.704, P < 0.01), TN(r =-0.722, P < 0.01), and TP(r =-0.882, P < 0.01) concentrations during wetland restoration, which indicates tha

关键词： inland soda saline-alkali wetland wetland degradation and restoration soil nutrients ecological stoichiometry Phragmites australis

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Scattering Phase Correction for Semiclassical Quantization Rules in Multi-Dimensional Quantum Systems

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Communications in Theoretical Physics 2010年第2期53卷 250-256页

作者： HUANG wen-Min mou Chung-Yu CHANG Cheng-Hung Department of Physics National Tsing-Hua University Hsinchu Taiwan physics Division National Center for Theoretical Sciences Hsinchu Taiwan Institute of Physics National Chiao Tung University Hsinchu Taiwan Institute of Mathematical Modeling and Scientific Computing National Chiao Tung University Hsinchu Taiwan

While the scattering phase for several one-dimensional potentials can be exactly derived, less is known in multi-dimensional quantum systems. This work provides a method to extend the one-dimensional phase knowledge to multi-dimensional quantization rules. The extension is illustrated in the example of Bogomolny＇s transfer operator method applied in two quantum wells bounded by step potentials of different heights. This generalized semiclassical method accurately determines the energy spectrum of the systems, which indicates the substantial role of the proposed phase correction. Theoretically, the result can be extended to other semiclassical methods, such as Gutzwiller trace formula, dynamical zeta functions, and semielassical Landauer Buttiker formula. In practice, this recipe enhances the applicability of semiclassical methods to multi-dimensional quantum systems bounded by general soft potentials.

关键词： Bogomolny's transfer operator semiclassical quantization rules quantum chaos

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