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Paraspinal approach for thoracolumbar fracture

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Chinese Journal of Traumatology 2011年第1期14卷 3-6页

作者： JIANG Rui WU Han WANG Jin-cheng LI wen-xuan WANG yang Department of Orthopedics China-Japan Union Hospital Jilin University Changchun 130033 China

Objective： To explore the advantages and indications of the paraspinal approach by anatomical study and clinical ***： The anatomical data and clinical practice of 27 cases were analyzed to explore the accurate approach between the paraspinal muscles and the structure of ambient tissues, as well as the results of clinical application of paraspinal approach. The operation time, blood loss, incision length, radiographic result （Cobb angle, height of anterior edge of the vertebrae） were compared with those in 24cases treated by traditional ***： Complete exposure of the facets could be easily performed by identifying natural cleavage plane between the multifidus and Iongissimus muscles. The natural muscular cleavage was （1.47±0.23） cm lateral to the midline for females, and （1.64±0.35） cm for males at T12 level. The distance was （3.3±0.6） cm lateral to the midline for females,and （3.7±1.0） cm for males at L4 level. In paraspinal approach group, the operation time was （76.2±15.7） min, blood loss was （91.6±16.9） ml and incision length was （7.6±0.8） cm. In traditional approach group, the operation time was （121.4±19.6） min, blood loss was （218.7±32.3 ） ml and incision length was （17.4±2.1） cm. To compare paraspinal approach with traditional approach, the operation time, blood loss and incision length had statistical difference （P〈0.05） and the radiographic result （Cobb angle, height of anterior edge of the vertebrae） had no statistical difference （P〉0.05）.Conclusions： When the paraspinal approach is performed through natural cleavage plane between the multifidus and longissimus muscles, there are no wide muscular disinsertions, leaving the supraspinous and interspinous ligaments intact. The distance of natural cleavage to the midline is different at T12 and L4 planes. By this approach,the facet joints can be explored easily and completely, and a clear surgical field will be available for the placement of pedicle screws. As a minimally invasive a

关键词： Fractures,bone Lumbar vertebrae Thoracic vertebrae Surgical procedures,operative

Eglin C与2709碱性蛋白酶相互作用分析及亲和纯化方法

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中国生物化学与分子生物学报 2021年第4期37卷 487-494页

作者：文阳宣周桂旭石亚伟山西大学生物技术研究所教育部化学生物学与分子工程重点实验室太原030006

Eglin C是来自水蛭中的一种小型热稳定蛋白质,属于马铃薯胰凝乳蛋白酶抑制剂家族,可以抑制弹性蛋白酶、枯草杆菌蛋白酶、组织蛋白酶、α-lytic蛋白酶以及胰凝乳蛋白酶等。然而,利用eglin C纯化蛋白酶,尚未见研究报道。本文将化学合成的... 详细信息

Eglin C是来自水蛭中的一种小型热稳定蛋白质,属于马铃薯胰凝乳蛋白酶抑制剂家族,可以抑制弹性蛋白酶、枯草杆菌蛋白酶、组织蛋白酶、α-lytic蛋白酶以及胰凝乳蛋白酶等。然而,利用eglin C纯化蛋白酶,尚未见研究报道。本文将化学合成的编码eglin C及其突变体的基因序列,克隆到原核表达载体pQE30,在大肠杆菌BL21获得His6-Tag-eglin C及其突变体的重组蛋白质。SDS-PAGE显示,eglin C蛋白的分子量大约8 kD。His6-Tag-eglin C对胰凝乳蛋白酶、地衣芽孢杆菌2709碱性蛋白酶、枯草芽孢杆菌PB92碱性蛋白酶、枯草杆菌中性蛋白酶的半抑制剂浓度(IC50)分别为0.20±0.15、0.24±0.19、3.33±0.47和52.46±0.38μmol/L。利用分子对接、基因突变以及荧光光谱等,分析eglin C及其突变体与2709蛋白酶的相互作用。结果显示,2709碱性蛋白酶对eglin C荧光淬灭属于静态淬灭,解离常数为2.60×10^(-7)mol/L,eglin C中的Asn50残基对eglin C和2709碱性蛋白酶的结合发挥重要作用。利用eglin C与蛋白酶的特异结合的特性,构建亲和纯化载体,用于纯化来源于地衣芽孢杆菌的2709碱性蛋白酶,相比常规的蛋白酶纯化,显著简化了操作步骤。

关键词： eglin C 碱性蛋白酶相互作用亲和纯化

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微波测湿原理及其在造纸工业上的应用

厦门大学学报(自然科学版) 1979年第2期 86-95页

作者：吕文选余扬政厦门大学物理系

从1974年开始,我们与福建青州造纸厂协作试制微波测湿仪,几年来初步取得一些成果。本文前一部份扼要介绍微波测温原理及其特点,后一部份介绍我们试制的几种微波测湿仪及实验结果。本文虽仅涉及造纸工业,但对其它工业部门也有一定的参考... 详细信息

从1974年开始,我们与福建青州造纸厂协作试制微波测湿仪,几年来初步取得一些成果。本文前一部份扼要介绍微波测温原理及其特点,后一部份介绍我们试制的几种微波测湿仪及实验结果。本文虽仅涉及造纸工业,但对其它工业部门也有一定的参考价值。

关键词：微波测湿仪青州造纸厂谐振腔体造纸工业造纸业

柠檬醛对阿糖胞苷抗白血病细胞HL-60强效增敏作用研究

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激光杂志 2010年第6期31卷 77-79页

作者：孙忠良戴舒柳宣文洋柯迪温海明罗曼暨南大学生物医学工程研究所广州510632

通过对柠檬醛与临床首选药物之一阿糖胞苷联用抗白血病细胞株HL-60的研究,探索二者联用的生物效应及其作用机制。采用MTT和DAPI核染色等方法观察柠檬醛同阿糖胞苷的不等浓度组合HL-60的增殖抑制和诱导凋亡作用,相分析电泳激光散射技术... 详细信息

通过对柠檬醛与临床首选药物之一阿糖胞苷联用抗白血病细胞株HL-60的研究,探索二者联用的生物效应及其作用机制。采用MTT和DAPI核染色等方法观察柠檬醛同阿糖胞苷的不等浓度组合HL-60的增殖抑制和诱导凋亡作用,相分析电泳激光散射技术检测联用对细胞表面电荷的影响。柠檬醛显示一定的抑制HL-60增殖,促进其凋亡的效应,并与阿糖胞苷有较显著的协同性,增加柠檬醛浓度与药物阿糖胞苷联合作用可使膜表面电位下降的幅度增大。柠檬醛有联合阿糖胞苷临床治疗潜力。

关键词：柠檬醛-阿糖胞苷白血病HL-60细胞作用机制

多GNSS融合伪距单点定位算法及其程序实现

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测绘与空间地理信息 2017年第9期40卷 47-51页

作者：杜文选刘扬耿加伟安徽理工大学测绘学院安徽淮南232001

随着GNSS技术的发展,目前具备独立服务能力的系统包括GPS、GLONASS和BDS。针对多GNSS融合导航定位的成为近几年研究的热点这一现象,本文对基于Visual Studio 2010 C++平台编写多GNSS融合伪距单点定位程序中出现的关键点做了详细叙述,详... 详细信息

随着GNSS技术的发展,目前具备独立服务能力的系统包括GPS、GLONASS和BDS。针对多GNSS融合导航定位的成为近几年研究的热点这一现象,本文对基于Visual Studio 2010 C++平台编写多GNSS融合伪距单点定位程序中出现的关键点做了详细叙述,详述了多GNSS伪距单点定位模型以及部分测量误差的改正,通过实例计算验证了多系统单点定位可以改善卫星结构,提高系统在复杂环境下测量时的稳定性,从而验证了程序的正确性与可行性。

关键词： GNSS融合单点定位 C++平台时空统一

Burden of mental disorders and risk factors in the Western Pacific region from 1990 to 2021

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World Journal of Psychiatry 2025年第1期15卷 93-105页

作者： Ya-Xin Xu Xiao-xuan Niu wen-Chang Jia Jing wen Xue-Lin Cheng Yan Han Ming-Hui Peng Jing Zhou Yao Liu Sun-Fang Jiang Xiao-Pan Li Department of Health Management Centre Zhongshan HospitalFudan UniversityShanghai 200030China Department of General Practice Zhongshan HospitalFudan UniversityShanghai 200030China Department of Nutrition Zhongshan HospitalFudan UniversityShanghai 200032China School of Public Health Fudan UniversityShanghai 200032China

BACKGROUND The burden of mental disorders(MD)in the Western Pacific Region(WPR)re-mains a critical public health concern,with substantial variations across demogra-phics and *** To analyze the burden of MD in the WPR from 1990 to 2021,along with associated risk factors,to reveal changing trends and emerging *** We used data from the Global Burden of Disease 2021,analyzing prevalence,incidence,and disability-adjusted life years(DALYs)of MD from 1990 to *** methods included age-standardisation and uncertainty analysis to address variations in population structure and data *** Between 1990 and 2021,the prevalence of MD rose from 174.40 million cases[95%uncertainty interval(UI):160.17-189.84]to 234.90 million cases(95%UI:219.04-252.50),with corresponding DALYs increasing from 22.8 million(95%UI:17.22-28.79)to 32.07 million(95%UI:24.50-40.68).During this period,the burden of MD shifted towards older age *** and anxiety disorders were predominant,with females showing higher DALYs for depressive and anxiety disorders,and males more affected by conduct disorders,attention-deficit hyperactivity disorder,and autism spectrum ***,New Zealand,and Malaysia reported the highest burdens,whereas Vietnam,China,and Brunei Darussalam reported the ***,childhood sexual abuse and bullying,and intimate partner violence emerged as significant risk *** This study highlights the significant burden of MD in the WPR,with variations by age,gender,and *** coronavirus disease 2019 pandemic has exacerbated the situation,emphasizing the need for a coordinated response.

关键词： Mental disorders Western pacific region Global Burden of Disease Risk factors Disability-adjusted life years

Contrasting Magnetism in Isovalent Layered LaSr3NiRuO4H4 and LaSrNiRuO4 due to Distinct Spin-Orbital States

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Chinese Physics Letters 2019年第7期36卷 98-102页

作者： xuan wen Ke yang Hua Wu Laboratory for Computational Physical Sciences (MOE) State Key Laboratory of Surface Physics and Department of Physics Fudan University Shanghai 200433 Collaborative Innovation Center of Advanced Microstructures Nanjing 210093

The recently synthesized first 4d transition-metal oxide-hydride LaSr3NiRuO4H4 with the unusual high H:O ratio surprisingly displays no magnetic order down to 1.8 K. This is in sharp contrast to the similar unusual low-valent Ni^+-Ru^2+ layered oxide LaSrNiRuO4 which has a rather high ferromagnetic(FM) ordering Curie temperature TC^250 K. Using density functional calculations with the aid of crystal field level diagrams and superexchange pictures, we find that the contrasting magnetism is due to the distinct spin-orbital states of the Ru^2+ions(in addition to the common Ni+S = 1/2 state but with a different orbital state): the Ru^2+S = 0 state in LaSr3NiRuO4H4, but the Ru^2+S= 1 state in LaSrNiRuO4. The Ru^2+S = 0 state has the(xy)^2(xz, yz)^4 occupation due to the RuH4O2 octahedral coordination, and then the nonmagnetic Ru2+ions dilute the S= 1/2 Ni^+ sublattice which consequently has a very weak antiferromagnetic superexchange and thus accounts for the presence of no magnetic order down to 1.8 K in LaSr3NiRuO4H4. In strong contrast, the Ru^2+S = 1 state in LaSrNiRuO4 has the(3z^2-r^2)^2(xz, yz)^3(xy)^1 occupation due to the planar square RuO4 coordination, and then the multi-orbital FM superexchange between the S= 1/2 Ni^+ and S= 1 Ru^2+ions gives rise to the high TC in LaSrNiRuO4. This work highlights the importance of spin-orbital states in determining the distinct magnetism.

关键词： The recently synthesized LaSr3NiRuO4H4

Sandwich教学法结合案例教学法在流行病学教学中的应用

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教育教学论坛 2017年第3期 173-175页

作者：李涛李曼刘文宣杨磊曹丹丹杨洁河北医科大学公共卫生学院流行病与卫生统计学教研室河北石家庄050017

流行病学理论性较强,传统教学法的教学效果欠佳。我们将Sandwich教学法结合案例教学法运用到流行病学的理论教学中,提高了学生的学习兴趣,培养了学生的学习主动性,以及分析问题、解决问题的能力。Sandwich教学法结合案例教学法使学生更... 详细信息

流行病学理论性较强,传统教学法的教学效果欠佳。我们将Sandwich教学法结合案例教学法运用到流行病学的理论教学中,提高了学生的学习兴趣,培养了学生的学习主动性,以及分析问题、解决问题的能力。Sandwich教学法结合案例教学法使学生更容易掌握流行病学的理论知识以及实际应用,取得了较好的教学效果。

关键词： Sandwich教学法案例流行病学教学改革

Low lighting image enhancement using local maximum color value prior

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Frontiers of Computer Science 2016年第1期10卷 147-156页

作者： xuan DONG Jiangtao wen Department of Computer Science and Technology Tsinghua University Beijing 100084 China

We study the problem of low lighting image en- hancement. Previous enhancement methods for images un- der low lighting conditions usually fail to consider the factor of image degradation during image formation. As a result, the lost contrast could not be recovered after enhancement. This paper will adaptively recover the contrast and adjust the exposure for low lighting images. Our first contribution is the modeling of image degradation in low lighting con- ditions. Then, the local maximum color value prior is pro- posed, i.e., in most regions of well exposed images, the lo- cal maximum color value of a pixel will be very high. By combining the image degradation model and local maximum color value prior, we propose to recover the un-degraded im- ages under low lighting conditions. Last, an adaptive expo- sure adjustment module is proposed to obtain the final result. We show that our approach enables better enhancement com- paring with popular image editing tools and academic algo- rithms.

关键词： low lighting enhancement image degradationmodel