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Journal of Rare Earths 2025年第1期43卷 64-72,I0003页

作者： Qianxiong wen Cong Zhao Meilin Fu Yusai Xu xiangjia Sun Jiaying Zheng Yanrong Liang Weidong xiang Xiaojuan Liang Zhaoping Chen College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou325035China College of Life and Environmental Science Wenzhou UniversityWenzhou325035China Institute of Stomatology School and Hospital of StomatologyWenzhou Medical UniversityWenzhou325027China

Phosphor-in-glass(PiG)has been prepared into various types of phosphor films owing to its simplicity process,exceptional color purity,and convenient color ***,existing reflective PiGs films have encountered limitations in terms of stability and feasibility as reliable color converters,mainly attributed to issues related to thermal deposition and insufficient optical ***,we propose to use AlN substrate with superior thermal conductivity to coat the TiO_(2) layer to obtain TiO_(2)-AlN(TA),which enhances the reflectivity of blue light to facilitate the light conversion *** incorporating highly thermally stable LuAG:Ce-PiGs on a TA substrate,the LuAG:Ce-PiTA converter exhibits a luminous flux of 1102 lm@6.4 W,and maintains a relative intensity of 94.6%at 473 K benefiting from the high thermal conductivity of 34.1 W/(m·K).The addition of CASN_(3):Eu to the color converter 50 L&10C-PiTA enables an impressive CRI of *** lumine scence intensities of LuAG:Ce-PiTA and 50 L&10C-PiTA only decrease by 5.35%and 3.28%,respectively,in the 24 h illumination aging decay test of the reflective laser *** results confirm the suitability of the optimally designed TA substrate for LuAG:Ce color converter applications in high-power reflective laser illumination.

关键词： TiO_(2)layer AIN substrate LuAG:Ce Color converter Laser illumination Rare earths

Prediction of the first 2^(+) states properties for atomic nuclei using light gradient boosting machine

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Nuclear Science and Techniques 2025年第2期36卷 95-102页

作者： Hui Liu Xin-xiang Li Yun Yuan wen Luo Yi Xu School of Nuclear Science and Technology University of South ChinaHengyang 421001China Extreme Light Infrastructure-Nuclear Physics(ELI-NP) Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering(IFIN-HH)Strada Reactorului 30Buchurest-Magurele077125 IlfovRomania

The first 2^(+)excited states of the nucleus directly reflect the interaction between the shell structure and the nucleus,providing insights into the validity of the shell model and nuclear structure *** the features of the first 2^(+)excited states can be measured for stable nuclei and calculated using nuclear models,significant uncertainty *** study employs a machine learning model based on a light gradient boosting machine(LightGBM)to investigate the first 2^(+)excited ***,the training of the LightGBM algorithm and the prediction of the first 2^(+)properties of 642 nuclei are ***,detailed comparisons of the LightGBM predictions were performed with available experimental data,shell model calculations,and Bayesian neural network *** results revealed that the average difference between the LightGBM predictions and the experimental data was 18 times smaller than that obtained by the shell model and only 70%of the BNN prediction *** Mg,Ca,Kr,Sm,and Pb isotopes as examples,it was also observed that LightGBM can effectively reproduce the magic number mutation caused by shell effects,with the energy being as low as 0.04 MeV due to shape ***,we believe that leveraging LightGBM-based machine learning can profoundly enhance our insights into nuclear structures and provide new avenues for nuclear physics research.

关键词： First 2^(+) state Nuclear levels Light gradient boosting machine

First documentation of early Silurian conodonts from western Thailand and its geological implications

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Journal of Palaeogeography 2025年第1期14卷 157-171页

作者： Zhong-Yang Chen Hathaithip Thassanapak wen-Jie Li Xue-Jin Wu Mongkol Udchachon xiang Fang Clive Burrett State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of Sciences University of Chinese Academy of Sciences Excellence Center in Evolution of Life Basin Studies and Applied Palaeontology Palaeontological Research and Education Center Mahasarakham University Department of Biology Faculty of Science Mahasarakham University

The early Silurian conodonts are firstly described and illustrated from western Thailand. Samples were collected from the Kroeng Kravia Forest Park area for conodont and lithofacies analyses. An upper Telychian Lower Pterospathodus amorphognathoides amorphognathoides Subzone is recognized for the studied succession. Three lithofacies were identified from the carbonate succession, including stromatolite-thrombolite limestone, nodular limestone, and red limestone. Both analyses on lithofacies and conodont assemblages indicate a deeper marine depositional environment. The conodont fauna in the study area is similar to that from Baoshan of Yunnan Province and Langao of Shaanxi Province in West China and resembles that from similar depositional environments in Australia, Laurentia, and peri-Gondwana, suggesting good connections among these regions by ocean currents.

关键词： Silurian Conodonts Deep marine environment Western Thailand Sibumasu

Synergistic mechanism of metal ions and sodium N-oleoylsarcosinate on flotation separation of lepidolite from feldspar

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Transactions of Nonferrous Metals Society of China 2025年第1期35卷 296-312页

作者： Guo-yuan xiang Rui-hua FAN wen-tao ZHU Wei SUN Ren-ji ZHENG Zhi-yong GAO School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China Hunan International Joint Research Centre for Efficient and Clean Utilization of Critical Metal Mineral Resources Central South UniversityChangsha 410083China Engineering Research Center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Central South UniversityChangsha 410083China

The combined reagents of sodium N-oleoylsarcosinate(SNOS)with metal ions(Ca(Ⅱ),Mg(Ⅱ),Cu(Ⅱ),and Pb(Ⅱ))was employed to facilitate the separation of lepidolite from *** synergistic interaction mechanism of this combined reagent was systematically investigated via contact angle measurements,AFM,FTIR,species distribution calculations,and DFT *** results suggested that Ca(Ⅱ)exhibited the best selectivity for activating lepidolite *** was chemically adsorbed on the Ca(Ⅱ)-activated lepidolite surface with an adsorption energy of−1248.91 kJ/mol while a lower adsorption energy of−598.84 kJ/mol of SNOS on Ca(Ⅱ)-activated feldspar was ***,this combination of SNOS and Ca(Ⅱ)is a promising reagent scheme for the efficient recovery of lithium from aluminosilicate ore.

关键词： flotation lepidolite feldspar sodium N-oleoylsarcosinate metal ions

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超等长训练方法的应用及其训练启示

体育学研究 2018年第5期1卷 78-88页

作者：刘瑞东徐文祥姜自立李庆清华大学体育部北京100084 杭州电子科技大学体育教学部浙江杭州310018 国家体育总局体育科学研究所北京100061

以生理学适应机制为依托,阐述了超等长训练方法的演变与进展,以及如何更合理地应用该训练方法。重点介绍了在训练实践中较为热门的负重超等长训练,以及在训练中最新兴起的水中和沙上超等长训练。水中和沙上超等长训练更加突出预防损伤... 详细信息

以生理学适应机制为依托,阐述了超等长训练方法的演变与进展,以及如何更合理地应用该训练方法。重点介绍了在训练实践中较为热门的负重超等长训练,以及在训练中最新兴起的水中和沙上超等长训练。水中和沙上超等长训练更加突出预防损伤的重要性,因此,如何更加合理地应用这一新方法,对于提高这一群体的运动成绩和防止运动损伤具有重要意义。研究认为:(1)弹跳高度、负重大小、弹跳速度和频率以及跳跃技巧等是影响超等长训练的关键因素。在进行超等长训练时,要强调"SSC"收缩的连贯性和动作速度;(2)在进行超等长训练时,不能过分追求跳深的高负重,较高的负重会使跳深触地时间和"SSC"收缩耦联时间延长,从而降低练习效果。因此,进行较低负重的跳深练习更利于提高爆发力;(3)沙上或水中超等长训练可作为陆上训练的辅助或交叉方式融入整个训练计划,促进超等长力量和专项成绩的提高,为运动员、特别是处于康复期运动员、青少年或女性运动员提供更多的选择。

关键词：运动训练等长训练超等长训练维尔霍山斯基运动损伤反应力量爆发力跳深

Andreev reflection in superconducting state of pressurized La3Ni2O7

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Science China(Physics,Mechanics & Astronomy) 2025年第04期Mechanics & Astronomy) .卷 184-192页

作者： Cong Liu Mengwu Huo Huan Yang Qing Li Yingjie Zhang Zhening xiang Meng Wang Hai-Hu wen National Laboratory of Solid State Microstructures and Department of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing University Center for Neutron Science and Technology Guangdong Provincial Key Laboratory of Magnetoelectric Physics and DevicesSchool of PhysicsSun Yat-sen University

The discovery of superconductivity with Tcabove 77 K in pressurized La3Ni2O7has stimulated enormous interest in the field of unconventional superconductivity.A recent experiment in La2PrNi2O7has shown that the superconducting volume is close to100%.Because the superconductivity can only be achieved under high pressures,many intrinsic properties,such as the superconducting gaps,have not been measured *** report the Andreev reflection measurement of pressurized La3Ni2O7with the onset superconducting transition temperature at about 77 *** data reveal a clear peak of differential conductivity near zero bias in the tunneling spectrum;and appear also are some temperature-dependent steps that may reflect other superconducting *** based on the Blonder-Tinkham-Klapwijk model with multiple components can roughly fit the data,and the central peak can be fitted with a d-wave gap with a magnitude of about 9 meV,and other two s-wave gaps at about 16 and 26 *** latter two large gaps are determined from the enhanced steps of the differential conductivity,which may have other *** results reveal possible evidence of a sign-reversal gap and multi-component features of the superconducting gaps in the nickelate 327 systems.

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Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

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World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： xiu-Ying Chen Fa Shen Chang Cheng Yu-Han Wang wen-Chao Cheng De-Zhi Yuan wen Huang Department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China Department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

基于代谢组学与网络药理学探究加味芎归汤改善APP/PS1小鼠认知障碍的作用机制

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中国中药杂志 2025年第2期50卷 322-334页

作者：向俊宝文雯徐世军成都中医药大学西南特色中药资源国家重点实验室四川成都610037 成都中医药大学药学院四川成都610037 成都中医药大学中医脑病药物整合转化研究所四川成都610037

该研究采用小鼠脑组织代谢组学整合网络药理学探究加味芎归汤治疗阿尔茨海默病(Alzheimer's disease,AD)的作用机制。选择6月龄的APP/PS1小鼠进行实验,分为APP/PS1组和加味芎归汤干预组,以同月龄的C57BL/6小鼠作为对照,观察小鼠的认知... 详细信息

该研究采用小鼠脑组织代谢组学整合网络药理学探究加味芎归汤治疗阿尔茨海默病(Alzheimer's disease,AD)的作用机制。选择6月龄的APP/PS1小鼠进行实验,分为APP/PS1组和加味芎归汤干预组,以同月龄的C57BL/6小鼠作为对照,观察小鼠的认知能力以及病理损伤;运用GC-MS/MS技术分析小鼠脑组织的代谢谱,筛选差异代谢物并富集相关代谢通路;采用网络药理学方法筛选加味芎归汤活性成分,构建其治疗AD的核心靶点的蛋白-蛋白相互作用网络并对加味芎归汤潜在治疗AD靶点进行基因本体论(Gene Ontology,GO)和京都基因与基因组百科全书(Kyoto Encyclopedia of Genes and Genomes,KEGG)富集分析;最后构建“代谢物-反应-酶-基因”网络进行代谢组学与网络药理学联合分析。结果显示加味芎归汤对小鼠脑组织中参与乙醛酸和二羧酸代谢,甘氨酸、丝氨酸和苏氨酸代谢,丙酮酸代谢,丙氨酸、天冬氨酸和谷氨酸代谢和三羧酸循环等(tricarboxylic acid cycle,TCA)15条代谢通路的18个差异代谢物有显著回调趋势;加味芎归汤的383个核心靶点参与了磷脂酰肌醇3-激酶(phosphoinositide 3-kinase,PI3K)/蛋白激酶B(protein kinase B,Akt)信号通路、钙离子信号通路等。整体分析显示能量代谢、氨基酸代谢和脂肪酸代谢是加味芎归汤治疗AD的关键代谢途径。结果表明,加味芎归汤可通过改善小鼠脑组织代谢保护神经细胞,进而发挥改善认知障碍的作用。

关键词：阿尔茨海默病加味芎归汤代谢组学网络药理学

Particular Chinese contributions to extracorporeal liver surgery

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Hepatobiliary & Pancreatic Diseases International 2025年第1期24卷 57-66页

作者： Abudusalamu Aini Qian Lu Hao wen wen-Tao Wang Tuerganaili Aji Zhi-Yu Chen Lei-Da Zhang Zhan-Yu Yang Jia-Yin Yang Hai-Ning Fan Wei-Lin Wang xiang-Cheng Li Yu Zhang Jia-Hong Dong Hepatopancreatobiliary Center Organ Transplantation CenterBeijing Tsinghua Changgung HospitalTsinghua UniversityBeijing 102218China Key Laboratory of Digital Intelligence Hepatology(Chinese Ministry of Education) School of Clinical MedicineTsinghua UniversityBeijing 100084China Research Unit of Precision Hepatobiliary Surgery Paradigm Chinese Academy of Medical SciencesBeijing 100010China Institute for Organ Transplantation and Bionics Institute for Precision MedicineSchool of Clinical MedicineTsinghua UniversityBeijing 100010China Hepatobiliary&Echinococcosis Surgery Digestive&Vascular Surgery CenterThe First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054China Department of Liver Surgery&Liver Transplantation Center West China Hospital of Sichuan UniversityChengdu 610041China Department of Hepatobiliary Surgery Southwest HospitalThe Army Medical UniversityChongqing 100089China Faculty of Hepato-Pancreato-Biliary Surgery Chinese People’s Army General HospitalBeijing 400038China Liver Transplantation Center&Organ Transplantation Center West China Hospital of Sichuan UniversityChengdu 610041China Hepatopancreatobiliary Surgery School of Clinical MedicineQinghai University Affiliated HospitalXining 810006China Department of Hepatobiliary Surgery The Second Affiliated HospitalZhejiang Univeristy School of MedicineHangzhou 310009China Department of Hepatobiliary Surgery The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Hepatobiliary Surgery Sichuan Provincial People’s HospitalChengdu 610072China

Extracorporeal liver surgery(ELS), also known as liver autotransplantation, is a hybrid(cross-fertilized) surgery incorporating the technical knowledge from extreme liver and transplant liver surgeries, and recently became more embraced and popularized among leading centers. ELS could be summarized into three major categories, namely, ex-situ liver resection and autotransplantation(ELRA), ante-situm liver resection and autotransplantation(ALRA) and auxiliary partial liver autotransplantation(APLA). The successful development of ELS during the past 37 years is definitely inseparable from continuous effort s done by Chinese surgeons and researchers. Especially, the precision liver surgery paradigm has allowed to transform ELS into a modularized, more simplified, and standardized surgery, to upgrade surgical skills, to improve peri-operative outcome and long-term survival, to increase the capability of surgeons to select more complex diseases and to expand the level of medical service to the population. This review highlights the Chinese contributions to the field of ELS, focusing thereby on features of different surgical types, technical innovations, disease selection and surgical indication, patient prognosis and future perspectives.

关键词： Ex-situ ex-vivo liver resection Ex-situ in-vivo liver resection Semi-ex-vivo liver resection Ex-situ liver resection after in-situ hepatectomy Liver autotransplantation Autologous liver transplantation Bench hepatectomy Back-table liver resection Precision liver surgery

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China(Life Sciences) 2025年第1期68卷 300-302页

作者： Ze-Min Lin Mai xiang wen-Hui Wei Shu-Hui Fan Li Chen Jie Wang Xiao-Qian Yang Chun-Hao Yang Shi-Jun He Jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China School of Pharmacy University of Chinese Academy of SciencesBeijing 100049China School of Pharmacy Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese MedicineShanghai 201203China Experiment Center for Science and Technology Shanghai University of Traditional Chinese MedicineShanghai 201203China

Dear Editor,Phenotypic drug discovery,which observes compound effects on physiology,has given way to targeting specific molecules,but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al.,2022).Osteoarthritis(OA)is a prevalent chronic joint disorder,primarily affecting knee joints,with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).This imbalance and the discharge of inflammatory mediators perpetuate the cycle of inflammation and tissue ***,controlling inflammation and modulating osteoclastogenesis are critical therapeutic targets for managing OA.

关键词： inflammation drugs