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Tetrabromobisphenol A exerts thyroid disrupting effects but has little overt impact on postnatal brain development and neurobehaviors in mice

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Journal of Environmental Sciences 2024年第8期142卷 1-10页

作者： Shilin Song Yuanyuan Li Lin lv Mengqi Dong Zhanfen Qin State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China School of Environment Tsinghua UniversityBeijing 100084China

Tetrabromobisphenol A(TBBPA)is a widely used brominated flame *** is evidence showing that TBBPA can exert thyroid disrupting effects in mammals,but different results were also reported,along with inconsistent reports regarding its ***,we investigated thyroid disrupting effects and neurotoxicity of TBBPA(5,50,500μg/(kg·day))to male mice following maternal and direct exposure through drinking water,with the antithyroid drug propylthiouracil(PTU)as the positive *** postnatal day(PND)15,we expectedly observed severe thyroid compensatory hyperplasia and cerebellar developmental retardation in PTU-treated *** highest dose of TBBPA also caused thyroid histological alteration but had no effects on cerebellar development in terms of Purkinje cell morphology and the thickness of the internal granular layer and the molecular layer of the *** puberty and adulthood,the thyroid morphological alterations became more pronounced in the TBBPA-treated animals,accompanied by decreased serum thyroid hormone ***,the 50 and 500μg/(kg·day)TBBPA groups showed a significant decrease in the serum level of serotonin,a neurotransmitter associated with anxiety ***,the highest dose group displayed anxiety-like behaviors in the elevated plus-maze test on PND 35,but this neurobehavioral alteration disappeared on PND ***,no changes in neurobehavioral parameters tested were found in TBBPAtreated animals at puberty and ***,all observations show that TBBPA can exert thyroid disrupting effects but has little overt impact on brain development and neurobehaviors in mice,suggesting that thyroid disruption does not necessarily cause overtly adverse neurodevelopmental outcomes.

关键词： Tetrabromobisphenol A Thyroid disruption Brain development Neurobehavior Cerebellum

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An air combat maneuver pattern extraction based on time series segmentation and clustering analysis

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Defence Technology（防务技术） 2024年第6期36卷 149-162页

作者： Zhifei Xi Yingxin Kou Zhanwu Li Yue lv You Li Air Force Engineering University No.1 Baling RoadBaqiao DistrictXi'anShaanxi ProvinceChina

Target maneuver recognition is a prerequisite for air combat situation awareness,trajectory prediction,threat assessment and maneuver *** get rid of the dependence of the current target maneuver recognition method on empirical criteria and sample data,and automatically and adaptively complete the task of extracting the target maneuver pattern,in this paper,an air combat maneuver pattern extraction based on time series segmentation and clustering analysis is proposed by combining autoencoder,G-G clustering algorithm and the selective ensemble clustering analysis ***,the autoencoder is used to extract key features of maneuvering trajectory to remove the impacts of redundant variables and reduce the data dimension;Then,taking the time information into account,the segmentation of Maneuver characteristic time series is realized with the improved FSTS-AEGG algorithm,and a large number of maneuver primitives are extracted;Finally,the maneuver primitives are grouped into some categories by using the selective ensemble multiple time series clustering algorithm,which can prove that each class represents a maneuver *** maneuver pattern extraction method is applied to small scale air combat trajectory and can recognize and correctly partition at least 71.3%of maneuver actions,indicating that the method is effective and satisfies the requirements for engineering *** addition,this method can provide data support for various target maneuvering recognition methods proposed in the literature,greatly reduce the workload and improve the recognition accuracy.

关键词： Maneuver pattern extraction Data mining Fuzzy segmentation Selective ensemble clustering

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Area Operators on Bergman Spaces

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1161-1176页

作者： Xiao Fen lv Jordi PAU Mao Fa WANG Department of Mathematics Huzhou UniversityHuzhou 313000P.R.China Departament de Matemàtiques i Informàtica Universitat de Barcelona08007 BarcelonaCataloniaSpain School of Mathematics and Statistics Wuhan UniversityWuhan 430072P.R.China

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0 详细信息

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0lve the cases left open there and extend the results to n-complex dimension.

关键词： Area operator Bergman space tent space area formula

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清末筹议放垦蒙地及在察哈尔地区的放垦实践

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云南社会科学 2024年第1期 113-123页

作者：吕文利马周睿中国社会科学院大学中国社会科学院中国边疆研究所

庚子之役后,为了应对统治危机,清廷接受岑春煊的建议解除蒙禁,并派贻谷推行垦务。察哈尔地区属内属蒙古,清廷对该地区的王公牧厂、私垦地进行大规模的放垦和清理,取得显著效果。在近代内忧外患的形势下,清末的垦务活动促进了中国内地与... 详细信息

庚子之役后,为了应对统治危机,清廷接受岑春煊的建议解除蒙禁,并派贻谷推行垦务。察哈尔地区属内属蒙古,清廷对该地区的王公牧厂、私垦地进行大规模的放垦和清理,取得显著效果。在近代内忧外患的形势下,清末的垦务活动促进了中国内地与蒙疆地区的一体化,推动中华民族形成嵌入式互动的发展格局,增强了中华各民族之间的凝聚力,使得维护国家统一的内在力量愈发深厚持久。

关键词：北疆开发察哈尔蒙地垦务嵌入式互动

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Longitudinal vibration characteristics of a tapered pipe pile considering the vertical support of surrounding soil and construction disturbance

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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 51-63页

作者： Li Zhenya Pan Yunchao He Xianbin lv Chong Mohammad Towhid Key Laboratory of Ministry of Education for Geomechanics and Embankment Engineering Hohai UniversityNanjing 210098China Geotechnical Research Institute Hohai UniversityNanjing 210098China MOE Key Laboratory of Soft Soils and Geoenvironmental Engineering Zhejiang UniversityHangzhou 310058China

This research is concentrated on the longitudinal vibration of a tapered pipe pile considering the vertical support of the surrounding soil and construction ***,the pile-soil system is partitioned into finite segments in the vertical direction and the Voigt model is applied to simulate the vertical support of the surrounding soil acting on the pile *** surrounding soil is divided into finite ring-shaped zones in the radial direction to consider the construction ***,the shear complex stiffness at the pile-soil interface is derived by solving the dynamic equilibrium equation for the soil from the outermost to innermost *** displacement impedance at the top of an arbitrary pile segment is obtained by solving the dynamic equilibrium equation for the pile and is combined with the vertical support of the surrounding soil to derive the displacement impedance at the bottom of the upper adjacent ***,the displacement impedance at the pile head is obtained based on the impedance function transfer ***,the reliability of the proposed solution is verified,followed by a sensitivity analysis concerning the coupling effect of the pile parameters,construction disturbance and the vertical support of the surrounding soil on the displacement impedance of the pile.

关键词： tapered pipe pile longitudinal vibration vertical support of the surrounding soil construction disturbance displacement impedance

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A brief review of tribological properties for black phosphorus

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Friction 2024年第5期12卷 823-844页

作者： Fanfan lv Wei WANG Jinjin LI Yuan GAO Kuaishe WANG College of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an710055China State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing10084China

Black phosphorus (BP) is a new class of two-dimensional (2D) layered material, which shows the unanticipated characteristics in many aspects including electronics, transistors, sensors, energy storage, batteries, photocatalysis, and other applications due to its high charge carrier mobility, tunable direct bandgap, and unique in-plane anisotropic structure. In addition, BP has drawn tremendous attention in the field of tribology due to the low shear strength, the layered structure, and the weak connected force between the layers by van der Waals interaction. In recent years, many significant progresses have been made in experimental studies on BP materials as solid lubricants or lubrication additives. This work offers a review of researching regarding the tribological properties of BP. Moreover, the lubrication mechanisms of BP as the lubrication additive including the formation of the tribo-film, micro-bearing effect, and self-repair performance are also summarized. Finally, the current challenges and prospects of BP material as lubricant are proposed.

关键词： black phosphorus(BP) two-dimensional(2D)layered material lubrication additives tribological mechanisms

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Sylvester级数展式中例外集的维数

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应用数学 2024年第2期37卷 373-376页

作者：吕美英薛文重庆师范大学数学科学学院重庆401331

在2018年,本文第一作者研究了实数的Sylvester级数展式中部分商的相对增长速度问题,并给出以一般函数速度增长的例外集的Hausdorff维数的下界.本文我们将进一步研究该集合,并精确刻画它的Hausdorff维数.同时作为应用,我们给出以多项式... 详细信息

在2018年,本文第一作者研究了实数的Sylvester级数展式中部分商的相对增长速度问题,并给出以一般函数速度增长的例外集的Hausdorff维数的下界.本文我们将进一步研究该集合,并精确刻画它的Hausdorff维数.同时作为应用,我们给出以多项式和指数速度增长时,相关例外集的维数结果.

关键词： Sylvester级数展式例外集 Hausdorff维数

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The heterogeneity of tumor-associated macrophages and strategies to target it

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BIOCELL 2024年第3期48卷 363-378页

作者： HAO lv BO ZHU DEGAO CHEN Institute of Cancer Xinqiao HospitalThird Military Medical UniversityChongqing400037China Chongqing Key Laboratory of Immunotherapy Xinqiao HospitalThird Military Medical UniversityChongqing400037China

Tumor-associated macrophages(TAMs)are emerging as targets for tumor therapy because of their primary role in promoting tumor *** studies have been conducted to target TAMs by reducing their infiltration,depleting their numbers,and reversing their phenotypes to suppress tumor progression,leading to the development of drugs in preclinical and clinical ***,the heterogeneous characteristics of TAMs,including their ontogenetic and functional heterogeneity,limit their ***,in-depth exploration of the heterogeneity of TAMs,combined with immune checkpoint therapy or other therapeutic modalities could improve the efficiency of tumor *** review focuses on the heterogeneous ontogeny and function of TAMs,as well as the current development of tumor therapies targeting TAMs and combination strategies.

关键词： Tumor-associated macrophages Tissue-resident macrophages Heterogeneity Immune checkpoint therapy

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Enhancing AI System Privacy:An Automatic Tool for Achieving GDPR Compliance in NoSQL Databases

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Computers, Materials & Continua 2024年第7期80卷 217-234页

作者： Yifei Zhao Zhaohui Li Siyi lv College of Cyber Science Nankai UniversityTianjin300350China

The EU’s Artificial Intelligence Act(AI Act)imposes requirements for the privacy compliance of AI *** systems must comply with privacy laws such as the GDPR when providing *** laws provide users with the right to issue a Data Subject Access Request(DSAR).Responding to such requests requires database administrators to identify information related to an individual ***,manual compliance poses significant challenges and is *** administrators need to write queries through time-consuming *** demand for large amounts of data by AI systems has driven the development of NoSQL *** to the flexible schema of NoSQL databases,identifying personal information becomes even more *** paper develops an automated tool to identify personal information that can help organizations respond to *** tool employs a combination of various technologies,including schema extraction of NoSQL databases and relationship identification from query *** describe the algorithm used by our tool,detailing how it discovers and extracts implicit relationships from NoSQL databases and generates relationship graphs to help developers accurately identify personal *** evaluate our tool on three datasets,covering different database designs,achieving an F1 score of 0.77 to *** results demonstrate that our tool successfully identifies information relevant to the data *** tool reduces manual effort and simplifies GDPR compliance,showing practical application value in enhancing the privacy performance of NOSQL databases and AI systems.

关键词： GDPR compliance NoSQL databases AI system privacy

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Recent progress of in-situ characterization of LiNi_(1−x−y)Co_(x)Mn_(y)O_(2) cathodes for lithium metal batteries: A mini review

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Nano Research 2024年第3期17卷 1384-1401页

作者： Huanzhu lv Xiaoqi Zhu Jun Mei Yuanhua Xia Bin Wang Institute of Fundamental and Frontier Science University of Electronic Science and Technology of ChinaChengdu 611731China Chengdu Development Center of Science and Technology China Academy of Engineering PhysicsChengdu 610200China Key Laboratory of Neutron Physics and Institute of Nuclear Physics and Chemistry China Academy of Engineering Physics(CAEP)Mianyang 621999China

In the context of the gradual popularity of electric vehicles(EVs),the development of lithium battery systems with high energy density and power density is regarded as the foremost way to improve the range of ***_(1-x-y)Co_(x)Mn_(y)O_(2)(NCM)cathodes have been the focus of researchers due to their high energy density,excellent power performance,and low-temperature ***,the elaboration of the decay mechanism of NCM cathode based on lithium metal batteries(LMBs)is still being restricted to the primary *** the past decades,the development and application of advanced in-situ characterization tools have facilitated researchers'understanding of the internal operation mechanism of batteries during charging and *** this minireview,the latest progress of in-situ observation of the NCM cathode by X-ray diffraction(XRD),fourier transform infrared(FT-IR)spectroscopy,Raman spectroscopy,atomic force microscopy(AFM),transmission electron microscope(TEM),optical microscope,and other characterization tools is *** mechanisms of structural degradation,cathode-electrolyte interfaces(CEIs)composition,and dynamic changes of NCM,electrolyte breakdown,and gas production are ***,based on the existing research progress,the opportunities and challenges for future in-situ characterization technology in the study of the mechanism of LMBs are discussed in ***,the purpose of this minireview is to summarize recent work that focuses on the outstanding application of in-situ characterization techniques in the mechanistic study of LMBs,and pointing the way to the future development of high energy density and power density LMBs systems.

关键词： lithium metal batteries(LMBs) In-situ characterization LiNi_(1-x-y)Co_(x)Mn_(y)O_(2)(NCM)

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