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Bayesian network-based survival prediction model for patients having undergone post-transjugular intrahepatic portosystemic shunt for portal hypertension

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World Journal of Gastroenterology 2024年第13期30卷 1859-1870页

作者： Rong Chen Ling luo Yun-Zhi Zhang Zhen Liu An-Lin Liu Yi-wen Zhang Department of Infectious Diseases Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Portal hypertension(PHT),primarily induced by cirrhosis,manifests severe symptoms impacting patient *** transjugular intrahepatic portosystemic shunt(TIPS)is a critical intervention for managing PHT,it carries risks like hepatic encephalopathy,thus affecting patient survival *** our knowledge,existing prognostic models for post-TIPS survival in patients with PHT fail to account for the interplay among and collective impact of various prognostic factors on ***,the development of an innovative modeling approach is essential to address this *** To develop and validate a Bayesian network(BN)-based survival prediction model for patients with cirrhosis-induced PHT having undergone *** The clinical data of 393 patients with cirrhosis-induced PHT who underwent TIPS surgery at the Second Affiliated Hospital of Chongqing Medical University between January 2015 and May 2022 were retrospectively *** were selected using Cox and least absolute shrinkage and selection operator regression methods,and a BN-based model was established and evaluated to predict survival in patients having undergone TIPS surgery for *** Variable selection revealed the following as key factors impacting survival:age,ascites,hypertension,indications for TIPS,postoperative portal vein pressure(post-PVP),aspartate aminotransferase,alkaline phosphatase,total bilirubin,prealbumin,the Child-Pugh grade,and the model for end-stage liver disease(MELD)*** on the above-mentioned variables,a BN-based 2-year survival prognostic prediction model was constructed,which identified the following factors to be directly linked to the survival time:age,ascites,indications for TIPS,concurrent hypertension,post-PVP,the Child-Pugh grade,and the MELD *** Bayesian information criterion was 3589.04,and 10-fold cross-validation indicated an average log-likelihood loss of 5.55 with a standard deviation of *** model’s acc

关键词： Bayesian network Cirrhosis Portal hypertension Transjugular intrahepatic portosystemic shunt Survival prediction model

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Emerging strategies and developments in oxygen reduction reaction using high-performance platinum-based electrocatalysts

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Nano Research 2024年第5期17卷 3516-3532页

作者： Asad Ali Aatto Laaksonen Guo Huang Shahid Hussain Shuiping luo wen Chen Pei Kang Shen Jinliang Zhu Xiaoyan Ji Energy Engineering Division of Energy ScienceLuleåUniversity of Technology97187 LuleåSweden Department of Materials and Environmental Chemistry Arrhenius LaboratoryStockholm UniversitySE-10691 StockholmSweden Center of Advanced Research in Bionanoconjugates and Biopolymers “Petru Poni”Institute of Macromolecular ChemistryIasi 700469Romania State Key Laboratory of Materials-Oriented and Chemical Engineering Nanjing Tech UniversityNanjing 211816China College of Materials Science and Engineering Shenzhen UniversityShenzhen 518060China School of Resources Environment and MaterialsState Key Laboratory of Processing for Non-ferrous Metal and Featured MaterialsGuangxi UniversityNanning 530004China

The global practical implementation of proton exchange membrane fuel cells(PEMFCs)heavily relies on the advancement of highly effective platinum(Pt)-based electrocatalysts for the oxygen reduction reaction(ORR).To achieve high ORR performance,electrocatalysts with highly accessible reactive surfaces are needed to promote the uncovering of active positions for easy mass *** this critical review,we introduce different approaches for the emerging development of effective ORR electrocatalysts,which offer high activity and *** strategies,including morphological engineering,geometric configuration modification via supporting materials,alloys regulation,core-shell,and confinement engineering of single atom electrocatalysts(SAEs),are discussed in line with the goals and requirements of ORR performance *** review the ongoing development of Pt electrocatalysts based on the syntheses,nanoarchitecture,electrochemical performances,and *** eventually explore the obstacles and research directions on further developing more effective electrocatalysts.

关键词： oxygen reduction reaction(ORR) Pt-based electrocatalysts proton exchange membrane fuel cells(PEMFCs) morphology and alloys strategies single atom electrocatalysts(SAEs)

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Karstsinnectes cehengensis(Cypriniformes:Nemacheilidae),a new species of cave fish from Guizhou,China

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Zoological Systematics 2024年第2期49卷 101-115页

作者： Xinrui Zhao Changting Lan tao luo Jing Yu Jiajun Zhou Ning Xiao Jiang Zhou School of Karst Sciences Guizhou Normal UniversityGuiyang 550025China School of Life Sciences Guizhou Normal UniversityGuiyang 550001China Zhejiang Forest Resource Monitoring Center Hangzhou 310020China Zhejiang Forestry Survey Planning and Design Company Limited Hangzhou 310020China Guiyang Healthcare Vocational University Guiyang 550081China

Four species of the genus Karstsinnectes,which live in dark,low-energy groundwater ecosystems,are currently recorded,mainly distributed in the upstream of the Pearl River,the Youjiang River and the Hongshui *** biodiversity surveys is particularly difficult due to the particular cave habitats inhabited by these *** this work,we describe a new cave fish of the genus Karstsinnectes,namely *** luo,Zhao&Zhou,***.,collected from the Beipanjiang River,the upstream of the Hongshui ***,the four individuals of the new species form a phylogenetically separate lineage,as the sister clade of ***,with a 9.4–9.5%genetic difference in mitochondrial Cyt ***,the new species can be distinguished from its congeners by a combination of the following morphological characteristics:body naked,without body color;eyes reduced,diameter 1.4–3.8%of head length;anterior and posterior nostrils adjacent,anterior nostril not elongated to a barbel-like tip;lateral line incomplete;caudal fin forked;dorsal-fin rays iii-7,pectoral-fin rays i-11–12,pelvic-fin rays i-7,anal-fin rays iii-5,with 14 branched caudal-fin *** discovery of this new species represents the northernmost distribution of species within the genus Karstsinnectes and the first record from Guizhou *** currently known species of this genus inhabited in caves,making them ideal organisms for studying historical river connectivity and cave formation process.

关键词： Diversity karst cave morphology phylogeny Karstsinnectes

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Highly efficient photo-thermal synergistic catalysis of CO_(2)methanation over La_(1-x)Ce_(x)NiO_(3)perovskite-catalyst

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Nano Research 2024年第9期17卷 7945-7956页

作者： Ting Li Zhen-Yu Zhang De-Cun luo Bo-Yu Xu Rong-Jiang Zhang Ji-Long Yao Dan Li tao Xie Institute of Industrial Catalysis School of Chemical Engineering and TechnologyXi’an Jiaotong UniversityXi’an 710049China

Solar-driven photo-thermal catalytic CO_(2)methanation reaction is a promising technology to alleviate the problems posed by greenhouse gases ***,designing advanced photo-thermal catalysts remains a research challenge for CO_(2)methanation *** this work,a series of ABO3(A=lanthanide,B=transition metal)perovskite catalysts with Ce-substituted LaNiO3(La_(1-x)Ce_(x)NiO_(3),x=0,0.2,0.5,0.8,1)were synthesized for CO_(2)*** La_(0.2)Ce_(0.8)NiO_(3) exhibited the highest CH_(4) formation rate of 258.9 mmol·g^(-1)·hcat-1,CO_(2)conversion of 55.4%and 97.2%CH_(4) selectivity at 300℃with the light intensity of 2.9 W·cm^(-2).Then the catalysts were thoroughly analyzed by physicochemical structure and optical properties *** partial substitution of the A-site provided more active sites for the adsorption and activation of CO_(2)/H_(2).The sources of the active sites were considered to be the oxygen vacancies(O_(v))created by lattice distortions due to different species of ions(La^(3+),Ce^(4+),Ce^(3+))and exsolved Ni0 by H_(2)*** catalysts have excellent light absorption absorbance and low electron-hole(e^(-)/h^(+))recombination rate,which greatly contribute to the excellent performance in photo-thermal synergistic catalysis(PTC)CO_(2)*** results of in situ irradiated electron paramagnetic resonance spectrometer(ISI-EPR)and ISI-X-ray photoelectron spectroscopy(XPS)indicated that the aggregation of unpaired electrons near the defects and Ni metal(from La and Ce ions to Ov and Ni0)accelerated adsorption and activation of CO_(2)/H_(2).At last,the catalyst properties and structure were correlated with the proposed reaction mechanism from the in situ diffuse reflection infrared Fourier transform spectrum(DRIFTS)*** in situ precipitation of the B-site enhanced the dispersion of Ni,while its enriched photoelectrons upon illumination further promote hydrogen *** H^(*)spillover accelerated t

关键词： photo-thermal catalysis CO_(2)methanation perovskite A-site substitution in situ diffuse reflection infrared Fourier transform spectrum(DRIFTS)

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Imaging, pathology, and diagnosis of solitary fibrous tumor of the pancreas: A case report and review of literature

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World Journal of Clinical Cases 2024年第5期12卷 995-1003页

作者： wen-wen Wang Shu-Ping Zhou Xiang Wu luo-luo Wang Yi Ruan Jun Lu Hai-Li Li Xu-Ling Ni Li-Li Qiu Xin-Hua Zhou Department of Hepatobiliary and Pancreatic Surgery The Affiliated Li Huili HospitalNingbo University School of MedicineNingbo 315000Zhejiang ProvinceChina Ningbo College of Health Sciences Ningbo College of Health SciencesNingbo 315000Zhejiang ProvinceChina Health Science Center Ningbo UniversityNingbo 315000Zhejiang ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou310006Zhejiang ProvinceChina Department of Diagnosis Ningbo Diagnostic Pathology CenterNingbo 315000Zhejiang ProvinceChina

BACKGROUND A solitary fibrous tumor(SFT)is often located in the pleura,while SFT of the pancreas is extremely ***,we report a case of SFT of the pancreas and discuss imaging,histopathology,and immunohistochemistry for accurate diagnosis and *** SUMMARY A 54-year-old man presented to our hospital with pancreatic occupancy for over a *** were no previous complaints of *** blood pressure was *** glucose,tumor markers,and enhanced computed tomography(CT)suggested a malignant *** the CT appearance of pancreatic cancer varies,we could not confirm the diagnosis;therefore,we performed endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB).Pathology and immunohistochemistry were consistent with SFT of the *** posto-perative pathology and immunohistochemistry were consistent with the puncture *** patient presented for a follow-up examination one month after discharge with no adverse *** Other diseases must be excluded in patients with a pancreatic mass that cannot be *** and pathological histology have diagnostic value for pancreatic *** puncture biopsy under ultrasound can help diagnose pancreatic masses that cannot be diagnosed *** is an effective treatment for SFT of the pancreas;however,long-term follow-up is strongly recommended because of the possibility of malignant transformation of the tumor.

关键词： Pancreas Neoplasm fibrous tumor Endoscopic ultrasound-guided fine-needle biopsy Treatment Case report

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Patterned microsphere-lens projection lithography using an electrohydrodynamic-jetprinting-assisted assembly

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Photonics Research 2024年第7期12卷 1502-1512页

作者： YA ZHONG HAIBO YU PEILIN ZHOU HONGJI GUO TIANMING ZHAO HAO luo YANGDONG wen XIAODUO WANG LIANQING LIU State Key Laboratory of Robotics Shenyang Institute of AutomationChinese Academy of SciencesShenyang 110016China Institutes for Robotics and Intelligent Manufacturing Chinese Academy of SciencesShenyang 110016China University of Chinese Academy of Sciences Beijing 100049China College of Mechanical and Electrical Engineering Henan Agricultural UniversityZhengzhou 450002China Institute of Urban Rail Transportation Southwest Jiaotong UniversityChengdu 610000China

Microlens arrays have been widely used in the fields of micro-optics and micro-and nanofabrication. Traditional preparation methods utilize commercial photoresists and thermosetting materials, thereby restricting the optical properties of microlenses. In recent years, significant advancements have been achieved in near-field super-resolution imaging by utilizing microspheres and forming arrays of microsphere lenses via self-assembly. However, self-assembly approaches lack flexibility in terms of pattern selection. This study proposes a method that utilizes electrohydrodynamic jet (E-jet) printing to code ultraviolet (UV)-curable adhesives and assist in the assembly of patterned microsphere-lens arrays. Simulation results demonstrate that the UV-curable adhesive has little impact on the optical properties of the microsphere lens. Moreover, the microsphere lens exhibits a superior imaging resolution compared with traditional microlenses. A projection-lithography system is developed to achieve an accurate alignment between the focal plane of the microsphere lenses and the plane of the photoresist, facilitating the fabrication of patterned nanostructures. The lithographic nanostructures have a minimum feature size of 850 nm. This method enables the fabrication of arrays of microsphere lenses with arbitrary patterns and presents an inexpensive and simple strategy for fabricating micro-and nanostructure arrays with submicrometer features.

关键词： projection utilize utilizing

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Switching Behavior of Cascode GaN Under Influence of Gate Driver

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CSEE Journal of Power and Energy Systems 2024年第4期10卷 1816-1833页

作者： Bin luo Guangzhao luo Sihai Li School of Automation Northwestern Polytechnical UniversityXi’an 710072China

With high-frequency,low power dissipation and high-efficiency characteristics,Gallium nitride(GaN)power devices are of significant benefit in designing high-speed motor drives,as they improve performance and reduce ***,due to the cascode structure,coupling with the parasitics in gate driver and power circuits,power converters based on cascode GaN are prone to overshoot and oscillate on switching waveforms,which may lead to serious EMC problems,or even device *** complicated structure of cascode GaN device makes the gate driver design comparatively *** analytical model of the switching process considering gate driver parameters is proposed in this *** influence of gate driver parameters on switching behavior is investigated from the perspective of switching speed,waveform overshoot,and power ***-offs among overshoot,switching speed,and power loss are discussed;guidelines to design gate driver parameters are given.

关键词： Gallium nitride(GaN) gate driver oscillation and overshoot switching characteristics

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Effects of Heterologously Overexpressing PIP5K-Family Genes in Arabidopsis on Inflorescence Development

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Phyton-International Journal of Experimental Botany 2024年第1期93卷 97-117页

作者： Mingda Yin Rui luo Tana Liang Qi wen Xiaotian Liang Yanpeng wen Xuemei Hu Zhiyan Wang Chang Gao wenjing Ren Fenglan Huang College of Life Science and Food Engineering Inner Mongolia Minzu UniversityTongliao028000China Key Laboratory of Castor Breeding of the State Ethnic Affairs Commission Inner Mongolia Minzu UniversityTongliao028000China Inner Mongolia Industrial Engineering Research Center of Universities for Castor Inner Mongolia Minzu UniversityTongliao028043China Inner Mongolia Key Laboratory of Castor Breeding and Comprehensive Utilization Inner Mongolia Minzu UniversityTongliao028000China Inner Mongolia Engineering Research Center of Industrial Technology Innovation of Castor Inner Mongolia Minzu UniversityTongliao028000China

Castor is one of the top 10 oil crops in the world and has extremely valuable *** inflorescences directly affect yield,so the study of inflorescence development is very important in increasing castor *** previous studies have shown that the PIP5K gene family(PIP5Ks)is associated with inflorescence *** this study,to determine the function of each PIP5K gene in castor,a female Lm-type castor line,aLmAB2,was used to determine the relative expression levels of the PIP5Ks in castor *** PIP5K genes were heterologously overexpressed in Arabidopsis thaliana,the relative expression of each gene and the effect on plants was determined in ***,and the relationships among the PIP5Ks in castor were *** expression levels of the PIP5Ks in the female Lm-type castor line aLmAB2 were *** relative expression levels of the PIP5K9 and PIP5K11 genes were high(p<0.05)in isofemale inflorescences,and those of PIP5K1,PIP5K2,PIP5K6,and PIP5K8 were high(p<0.05)in female inflorescences but low(p<0.05)in bisexual *** PIP5Ks were heterologously overexpressed in ***,and T3-generation plants with stable genetic resistance,i.e.,AT-PIP5K^(+)plants(AT-PIP5K1^(+),AT-PIP5K2^(+),AT-PIP5K6^(+),AT-PIP5K8^(+),AT-PIP5K9^(+),and ATPIP5K11^(+) plants),were *** tests of the AT-PIP5K+plants showed that the growth of the main stem was significantly delayed in AT-PIP5K+plants compared with Columbia wild-type(WT)*** plants;the PIP5K1 and PIP5K2 genes promoted lateral stem growth and flower and silique development;and the PIP5K6,PIP5K8,PIP5K9 and PIP5K11 genes inhibited lateral stem growth and flower and silique *** correlations among PIP5Ks in castor suggest that there may be a synergistic relationship among PIP5K1,PIP5K2,and PIP5K6 in castor inflorescences,and PIP5K8,PIP5K9,and PIP5K11 are complementary to the other three genes.

关键词： Castor inflorescence development PIP5K gene family gene overexpression

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Ankylosing spondylitis coexisting with Clonorchis sinensis infection: A case report

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World Journal of Clinical Cases 2024年第5期12卷 1018-1024页

作者： Tian-Xin Yi Wei Liu wen-Fei Leng Xiao-Chuan Wang Liang luo Department of Rheumatology Traditional Chinese Medicine Hospital Dianjiang ChongqingChongqing 408300China Department of Orthopaedic Traditional Chinese Medicine Hospital Dianjiang ChongqingChongqing 408300China Department of Chinese Medicine The People's Hospital of Yubei District of Chongqing CityChongqing 401120China

BACKGROUND Ankylosing spondylitis(AS)is a chronic immune-mediated inflammatory *** prevailing theory links AS onset to infections in susceptible ***,infections may impair the immune *** studies have investigated links between AS and various infections-bacterial,viral,fungal,and other microorganism ***,limited attention has been given to the association between AS and Clonorchis sinensis(***)*** SUMMARY A 27-year-old male with a 10-yr history of AS presented to our hospital with inflammatory lower back pain as the primary *** years ago,the patient had achieved a stable condition after treatment with biological ***,he experienced a recurrence of lumbosacral pain with an unexplained cause 10 d before hospital admission.A lumbosacral magnetic resonance imaging(MRI)scan revealed bone marrow edema in the left sacroiliac joint,and laboratory indicators were ***,the presence of *** eggs was detected in the *** patient was prescribed praziquantel,resulting in the disap-pearance of *** eggs in subsequent routine stool tests and relief from lumbosacral pain.A follow-up MRI scan performed after 4 months revealed a reduction in bone marrow edema around the left sacroiliac *** *** infections could potentially trigger the exacerbation of *** should pay attention to investigating the presence of *** Ankylosing spondylitis(AS)is a chronic inflammatory and rheumatic disease resulting from an imbalance between innate and acquired immune responses[1].While it can affect any part of the spine,its primary symptoms are persistent back pain and stiffness in the lower back and *** prevalence of AS per 10000 individuals is 23.8 in Europe,31.9 in North America,16.7 in Asia,10.2 in Latin America,and 7.4 in Africa[2].Infections commonly occur in the first 3 months and may act as potential triggers for the

关键词： Ankylosing spondylitis Clonorchis sinensis Parasites Infection Case report

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Ketogenic diet therapy in children with epilepsy caused by SLC2A1 mutations:a single-center single-arm retrospective study

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World Journal of Pediatrics 2024年第5期20卷 517-524页

作者： Ying-Yan Wang Yun-Qing Zhou Li-Juan luo Cui-Jin Wang Nan Shen Hao Li Ji-wen Wang Department of Neurology Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Infectious Diseases Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Clinical Research Ward Clinical Research CenterShanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Background This retrospective study assessed the efficacy and safety of ketogenic diet therapies in children with epilepsy caused by SLC2A1 genetic mutations and glucose transporter type 1 deficiency *** Pediatric patients with epilepsy symptoms admitted to our medical center between January 2017 and October 2021 were included if they presented with an SLC2A1 genetic mutation on whole-exome *** analyzed the patients’convulsions and treatment with antiepileptic *** patients were followed up at different time periods after ketogenic diet *** Six patients with SLC2A1 mutations were included in this *** patients had seizures of different types and frequencies,and they took antiepileptic drugs to relieve their *** were then treated with a ketogenic diet for at least four *** analyzed epilepsy control rates at 1,2,3,6,and 12 months after ketogenic diet *** patients were seizure-free within a month of receiving the diet *** patients were followed up for six months,three were followed up for 12 months after the treatment,and there was no recurrence of epilepsy during this *** antiepileptic drug withdrawal,none of the patients experienced seizure relapse when receiving ketogenic diet treatment *** severe adverse events occurred during the *** Ketogenic diet therapy is very effective and safe for the treatment of epilepsy caused by SLC2A1 ***,patients with glucose transporter type 1 deficiency syndrome caused by SLC2A1 mutations should begin ketogenic diet treatment as soon as possible.

关键词： Epilepsy Glucose transporter type 1 Ketogenic diet SLC2A1

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