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Combined molybdenum target X-ray and magnetic resonance imaging examinations improve breast cancer diagnostic efficacy

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World Journal of Clinical Cases 2022年第2期10卷 485-491页

作者： wen-quan gu Sun-Mei Cai Wei-Dong Liu Qi Zhang Ying Shi Li-Juan Du Department of Radiology Punan HospitalShanghai 200126China

BACKGROUND Early-stage breast cancer patients often lack specific clinical manifestations,making diagnosis *** target X-ray and magnetic resonance imaging(MRI)examinations both have their own ***,a combined examination methodology may improve early breast cancer *** To explore the combined diagnostic efficacy of molybdenum target X-ray and MRI examinations in breast *** Patients diagnosed with breast cancer at our hospital from March 2019 to April 2021 were recruited,as were the same number of patients during the same period with benign breast *** groups underwent molybdenum target X-ray and MRI examinations,and diagnoses were given based on each *** single(i.e.,X-ray or MRI)and combined(i.e.,using both methods)diagnoses were counted,and the MRI-related examination parameters(e.g.,T-wave peak,peak and early enhancement rates,and apparent diffusion coefficient)were compared between the *** In total,63 breast cancer patients and 63 benign breast tumor patients were *** detected 53 breast cancer cases and 61 benign breast tumor *** target X-ray detected 50 breast cancer cases and 60 benign breast tumor *** combined methodology detected 61 breast cancer cases and 61 benign breast tumor *** sensitivity(96.83%)and accuracy(96.83%)of the combined methodology were higher than single-method MRI(84.13%and 90.48%,respectively)and molybdenum target X-ray(79.37%and 87.30%,respectively)(P0.05).The Twave peak(169.43±32.05)and apparent diffusion coefficient(1.01±0.23)were lower in the breast cancer group than in the benign tumor group(228.86±46.51 and 1.41±0.35,respectively).However,the peak enhancement rate(1.08±0.24)and early enhancement rate(1.07±0.26)were significantly higher in the breast cancer group than in the benign tumor group(0.83±0.1

关键词： Molybdenum X-rays Magnetic resonance imaging Breast neoplasms Early diagnosis Radiology

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克尔凯郭尔与卢卡奇马克思主义哲学观的流变

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武汉大学学报（哲学社会科学版） 2025年第1期78卷 77-85页

作者：温权武汉大学马克思主义学院湖北武汉430072

克尔凯郭尔并非卢卡奇偶然提及的学术注脚,而是其理解马克思的背景支援。卢卡奇在不同时期都对克尔凯郭尔作了选择性评述,并将其接受或重构马克思主义哲学的曲折心路历程逐一呈现:通过质疑克尔凯郭尔在人与世界相统一问题上遭遇的“审... 详细信息

克尔凯郭尔并非卢卡奇偶然提及的学术注脚,而是其理解马克思的背景支援。卢卡奇在不同时期都对克尔凯郭尔作了选择性评述,并将其接受或重构马克思主义哲学的曲折心路历程逐一呈现:通过质疑克尔凯郭尔在人与世界相统一问题上遭遇的“审美—伦理”悖论,青年卢卡奇从心灵掘进到阶级意识,将“主体—总体”辩证图式看作马克思的认识论地平,由此创作出《历史与阶级意识》;之后,为回应该书引起的争议,盛年的卢卡奇以批判克尔凯郭尔的非理性主义为契机,尝试清除“主体—总体”辩证图式中残余的主体形而上学痕迹,开始在方法论维度正视生产实践与经济规律间的有机联系;及至晚年,当卢卡奇立足社会存在,抨击克尔凯郭尔有关主体优先性的宗教幻象时,他又把社会性的“自在—自为”运动内嵌于人性的“主体—总体”辩证图式,并根据超然的悟性,默认马克思主义哲学是将经济规律置于从属地位的劳动本体论,再度退回《历史与阶级意识》的主体形而上学谋划。不难看出,在卢卡奇臧否克尔凯郭尔与马克思的“主体—总体”辩证桥段中,当事人对“人之实然性和应然性的现实统一”问题所秉持的龃龉心态暴露无遗。这也恰好说明,卢卡奇一生都徘徊于正统的马克思主义与人道的马克思主义之间。

关键词： “主体—总体”辩证图式克尔凯郭尔卢卡奇《历史与阶级意识》

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Literature study on traditional Chinese medicine syndromes after renal transplantation

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World Journal of Transplantation 2025年第1期15卷 150-155页

作者： Yun-Peng guo Ling-Xue Bao Yu-Yang Wang quan wen Gai Hang Bo Chen Tongliao Clinical Medical College Inner Mongolia Medical UniversityTongliao 028000Inner Mongolia Autonomous RegionChina Department of Urology Tongliao People's HospitalTongliao 028000Inner Mongolia Autonomous RegionChina

BACKGROUND Kidney transplantation is the most effective means to treat patients with renal failure,but its postoperative problems such as rejection reactions,immunosuppressant poisoning,chronic transplant kidney nephropathy,*** have not been effectively *** study searched for literature on traditional Chinese medicine(TCM)syndromes after kidney transplantation in China,conducted statistical analysis of the results,and sought to identify the underlying *** To understand the TCM syndromes after renal transplantation and associated rules and provide a theoretical basis for further clinical *** The literature pertaining to TCM syndromes in renal transplantation,published in the China National Knowledge Infrastructure,Wanfang database,and WIP database from 1970 to 2021,was meticulously searched and comprehensively and statistically *** Following the established inclusion and exclusion criteria,13 studies were selected for ***-renal transplantation,no significant discrepancy was noted among the groups based on the location of TCM ***,when categorized according to TCM pathogenic factors,the groups with spleen and kidney yang deficiency,as well as liver and kidney yin deficiency,exhibited a statistically significant difference in the *** Currently,the research on TCM syndromes pertaining to renal transplantation is in its nascent *** is imperative to conduct a multicentric,large-scale survey of TCM syndromes subsequent to renal transplantation in the ensuing years.

关键词： Kidney transplantation Syndrome Literature analysis Traditional Chinese medicine Systematic review

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锗锡浓度对硅锗锡合金性能影响的研究

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原子与分子物理学报 2025年第5期42卷 163-174页

作者：顾永顺温淑敏内蒙古工业大学理学院呼和浩特010051

由于SiGeSn合金材料其具有高的载流子迁移率和较长的载流子寿命,并且其结构具有较高的热力学稳定性,所以在光电子领域中是一种具有非常大应用潜力的半导体材料.本文采用密度泛函理论中的广义梯度近似GGA+U的方法,构建并计算了本征半导体... 详细信息

由于SiGeSn合金材料其具有高的载流子迁移率和较长的载流子寿命,并且其结构具有较高的热力学稳定性,所以在光电子领域中是一种具有非常大应用潜力的半导体材料.本文采用密度泛函理论中的广义梯度近似GGA+U的方法,构建并计算了本征半导体Si_(96)与五组掺杂模型Si_(92)Ge_(2)Sn_(2)、Si_(88)Ge_(4)Sn_(4)、Si_(84)Ge_(6)Sn_(6)、Si_(80)Ge_(8)Sn_(8)、Si_(76)Ge_(10)Sn_(10)的电子结构及光学性质.通过对计算结果的分析可知,Ge,Sn的加入使得Si材料的带隙宽度减小,并且发生了由间接带隙向直接带隙的转变;Ge,Sn浓度最高的SiGeSn合金的形成能相对较高,稳定性相较于Ge,Sn含量低的材料较差;随着Ge,Sn掺杂浓度的提高,电子态密度图显示出越来越明显的杂化现象,并且态密度的峰值主要有Si原子的s轨道提供;Ge,Sn浓度的提高还使得SiGeSn合金的吸收系数在可见光及近红外区域内增加、反射率在可见光及以上波段范围内提高、折射率变低、消光系数曲线向红外区域移动等光学性质变化,表明可以通过调节Ge,Sn浓度来获得合适的光学特性,这为SiGeSn半导体在红外区域光电材料和器件的应用上提供了研究方向.

关键词： SiGeSn 电子特性光学性质

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C–C formation mediated by photoinduced electrons from crystallized carbon nitride nanobelts under visible light irradiation

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Journal of Energy Chemistry 2019年第3期28卷 152-161页

作者： Qiaohui Jia Sufen Zhang quan gu Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University

Crystal structure and crystallinity of carbon nitride support, size and dispersity of active-metal nanoparticles(NPs), and surface engineering of composites have great roles in generation and separation of photogenerated charge carries and photocatalyzed organic reactions for the conversion of solar energy into chemical energy. Herein, we deposited well-dispersed Pd NPs with small size on crystallized carbon nitride(CN–C) to construct a Schottky-type Pd/CN–C hybrid for photocatalyzed Ullmann C–C homocoupling of aryl halides under visible light irradiation at room temperature. Compared to Pd NPs supported g-C_3N_4(Pd/g-C_3N_4), Pd/CN–C exhibits excellent visible light photocatalytic activity for Ullmann C–C coupling of aryl halides due to high crystallinity of CN–C support, high dispersion and smaller size of Pd NPs, and the interfacial heterojunction of Pd/CN–C. Upon visible light irradiation, more photogenerated electrons from CN–C flow across the Schottky junction to metallic Pd and trigger the Ullmann C–C coupling of aryl halides. The photogenerated holes on CN–C surface are captured by a protic solvent(such as EtOH). In the presence of base K_2CO_3, the solvent undergoes dissociation, dehydrogenation, and finally can be oxidized by captured photogenerated holes. Moreover, Pd/CN–C has general applicability for various substrates and shows excellent stability and reusability for more than nine cycles.

关键词： Crystallized carbon nitride Pd nanoparticles Photocatalyst C–C coupling Ullmann reaction

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Across-wind loads and effects of super-tall buildings and structures

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Science China(Technological Sciences) 2011年第10期54卷 2531-2541页

作者： gu Ming quan Yong State Key Laboratory of Disaster Reduction in Civil Engineering Tongji University Shanghai 200092 China

Across-wind loads and effects have become increasingly important factors in the structural design of super-tall buildings and structures with increasing height. Across-wind loads and effects of tall buildings and structures are believed to be excited by inflow turbulence, wake, and inflow-structure interaction, which are very complicated. Although researchers have been focusing on the problem for over 30 years, the database of across-wind loads and effects and the computation methods of equivalent static wind loads have not yet been developed, most countries having no related rules in the load codes. Research results on the across-wind effects of tall buildings and structures mainly involve the determination of across-wind aerodynamic forces and across-wind aerodynamic damping, development of their databases, theoretical methods of equivalent static wind loads, and so on. In this paper we first review the current research on across-wind loads and effects of super-tall buildings and structures both at home and abroad. Then we present the results of our study. Finally, we illustrate a case study in which our research results are applied to a typical super-tall structure.

关键词： super-tall building and structure across-wind aerodynamic force across-wind aerodynamic damping across-wind effects across-wind quivalent static wind loads case study

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基于输出特性仿真的引信传爆管结构优化

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爆破器材 2016年第5期45卷 23-28页

作者：刘鹏王雨时闻泉黄建强谷宝成张志彪南京理工大学机械工程学院江苏南京210094 岳阳金秋红日工业有限公司湖南岳阳414001 山东红旗机电有限公司山东潍坊261108

针对引信细长传爆管结构可生产性差的问题,应用有限元仿真软件ANSYS/LS-DYNA对不同结构和不同长度的传爆管输出特性进行了仿真,得到了不同结构和不同长度传爆管起爆后作用在战斗部炸药柱各点上的压力-时间历程曲线,并通过冲击起爆理论... 详细信息

针对引信细长传爆管结构可生产性差的问题,应用有限元仿真软件ANSYS/LS-DYNA对不同结构和不同长度的传爆管输出特性进行了仿真,得到了不同结构和不同长度传爆管起爆后作用在战斗部炸药柱各点上的压力-时间历程曲线,并通过冲击起爆理论判断不同结构和不同长度传爆管的起爆能力。结果表明,输出端面带有聚能凹槽的传爆管相比于传统的平底传爆管,起爆能力较强,所需传爆药量少,轴向尺寸也最短。39发起爆试验验证了仿真可信性。

关键词：传爆管数值仿真结构优化冲击起爆

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东北部分地区山荆子种质资源表型多样性及聚类分析

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植物遗传资源学报 2016年第6期17卷 984-992页

作者：冯章丽于文全顾广军刘畅卜海东程显敏刘延杰董雪梅邢星黑龙江省农业科学院牡丹江分院牡丹江157041

对我国东北地区收集的239份山荆子资源的树姿、叶形以及果形等19个表型性状多样性进行了研究。结果表明,我国黑龙江省和内蒙古自治区山荆子具有丰富的表型多样性,平均变异系数和平均多样性指数分别为32.65%和1.38,其中树姿、树型以及叶... 详细信息

对我国东北地区收集的239份山荆子资源的树姿、叶形以及果形等19个表型性状多样性进行了研究。结果表明,我国黑龙江省和内蒙古自治区山荆子具有丰富的表型多样性,平均变异系数和平均多样性指数分别为32.65%和1.38,其中树姿、树型以及叶片颜色等13个目测性状的平均变异系数为38.43%,平均遗传多样性指数为0.95,而叶长、叶宽以及叶柄长等6个测量性状的平均变异系数为26.87%,平均遗传多样性指数为1.80。进一步分析发现,不同地区山荆子表型多样性存在差异,以黑龙江温春山荆子多样性水平最高。基于19个表型性状的聚类分析发现,在欧氏距离为2.5时,参试山荆子材料可以划分为2大类,7个亚类,各地区山荆子材料聚类较为分散,没有形成独立的分类群,暗示山荆子材料遗传基础较为复杂。

关键词：山荆子种质资源表型多样性多样性指数聚类分析

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Mechanism of action of Linggui Zhugan Decoction in treating non-alcoholic fatty liver disease using untargeted metabolomics approach

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Traditional Medicine Research 2025年第2期10卷 65-76页

作者： Huan Pei Ren-Lin Li Xin-Ran Song Qian-Qian Wan Yu-Ming Wang Han-Zhou Li Wei-quan Xu Jia-Bao Liao Wei-Bo wen Jing Miao Huan-Tian Cui School of Basic Medicine Yunnan University of Chinese MedicineKunming 650599China School Clinical Medical College Yunnan University of Chinese MedicineKunming 650599China First School of Clinical Medicine Yunnan University of Chinese MedicineKunming 650599China School of Integrative Chinese and Western Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Pharmacy Tianjin Second People's HospitalTianjin 300192China

Background:Non-alcoholic fatty liver disease(NAFLD)is a liver disorder characterized by the accumulation and degeneration of fat in the liver cells,a condition that may further deteriorate and lead to cirrhosis and liver *** studies showed that metabolic dysfunction can promote NAFLD *** Zhugan Decoction(LGZGD)has therapeutic effects on *** mechanism of LGZGD still remains *** study was to examine the impact of LGZGD on the metabolic processes involved in the development of ***:A mice model of NAFLD was treated with *** therapeutic potential of LGZGD was evaluated by assessing the activity of transaminases,lipids levels of blood,and pathological changes in the liver of the mice model of ***,this study also evaluated the influence of LGZGD on liver inflammation and oxidative ***:The results of untargeted metabolomics analysis showed that LGZGD reduced the disordered lipid metabolism in NAFLD *** improved the oxidative stress and also reduced the levels of pro-inflammatory cytokines in the *** metabolomics analysis of liver samples revealed that LGZGD treatment improved metabolic disorders,including alanine,aspartate,glutamate,glycerophospholipid metabolism,and citrate *** RT-qPCR and Western blot results showed that LGZGD could regulate the expression of key enzymes in the metabolic pathway of the citrate cycle,including ATP-citrate lyase(ACLY),alanine-glyoxylate aminotransferase-2(AGXT2),phosphatidylethanolamine N-methyltransferase(PEMT),and succinate dehydrogenase(SDH).Conclusion:We found that LGZGD can treat NAFLD by reducing inflammatory responses,inhibiting oxidative stress,regulating alanine,aspartate,glutamate,and glycerophospholipid metabolism,and citrate cycle pathways.

关键词： NAFLD LGZGD untargeted metabolomics glycerophospholipid metabolism citrate cycle

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quantum model for understanding protein misfolding behavior——phase diagram and manual intervention

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Science China(Physics,Mechanics & Astronomy) 2021年第6期64卷 10-16页

作者： wen-wen Mao Li-Hua Lu You-quan Li Zhejiang Province Key Laboratory of quantum Technology&Device and Department of Physics Zhejiang UniversityHangzhou 310027China Collaberative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210008China

The study of protein folding is fundamental and important in the multidisciplinary field because a diversity of diseases,like Alzheimer’s and Parkinson’s are relevant to protein *** current thermodynamic and geometric approaches only phenomenologically describe but do not provide a mechanistic understanding of the competition between correct folding and *** we present a model to understand the misfolding *** the influence of dissipative strength for all possible sequences and comparing the folding time toward different compact structures,we obtain a phase diagram of the dissipative quantum phase transition that enables us to model the *** also investigate how a perturbation in the Hamiltonian affects the transition point,which motivates us to explore possible manual *** results indicate that the manual intervention may be effective for some specific sequence but not for *** approach is expected to lay a foundation for further studies on manual intervention in protein misfolding.

关键词： quantum phase diagram quantum walk mean first-passage time protein folding

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