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Progress in Natural Science:Materials International 2007年第6期17卷 703-707页

作者： Chen Zhi, lin wen, yu Ping and Song yuan(Department of Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100094, China) Department of Superconductivity University of Tokyo Bunkyo-ku Tokyo 113 Japan Department of Microbiology College of Biological Sciences China Agricultural University Beijing 100094 China

Intergenric protoplast fusion between Aspergillus terreus CA99 and Monascus anka M-3, the high and low producers of monacolin K respectively,was performed for enhancement of monacolin K production. The 24-hour-old mycelia of A. terreus CA99 and M. anka M-3 were treated with 0.5% lywallzyme, 0.3% snailase and 0.3% cellulase at 34℃ for 5 h and at 30℃ for 3.5 h, and their protoplasts formation reached 1.76×107/mL and 1.68×107/mL respectively. Parental protoplasts were irradiated with a 30 W UV light away from 30 cm for 3 min and then mixed. The mixture was incubated with 30% PEG 6000 for 15 min. The reviving fusants were isolated on the regeneration plates. Of the 363 fusants isolated, over 100 showed enhanced monacolin K production compared with the parental strain M. anka M-3. Ten of them produced monacolin K about 1.6-fold of that *** M-3 does and the monacolin K titer of two fusants (F49 and F104) increased by about 1-fold. The monacolin K yields of F49 and F104 were 460 μg/mL and 457 μg/mL respectively. In optimized fermentation medium, the monacolin K titer of F49 reached 1216 μg/mL.

关键词： monacolin K Monascus anka Aspergillus terreus protoplast fusion fermentation.

不可还原的意向性:托马斯·里德与维特根斯坦

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河北学刊 2016年第6期36卷 27-32页

作者：文玉林复旦大学哲学学院上海200433

西方近代哲学中的观念论是一种意向性还原理论。在18世纪,观念论被苏格兰哲学家托马斯·里德激烈批评;在20世纪,观念论受到维特根斯坦的猛烈批判。两位哲学家都拒绝观念论的意向性还原论进路,坚持意向性的不可还原性。但对于为什么意向... 详细信息

西方近代哲学中的观念论是一种意向性还原理论。在18世纪,观念论被苏格兰哲学家托马斯·里德激烈批评;在20世纪,观念论受到维特根斯坦的猛烈批判。两位哲学家都拒绝观念论的意向性还原论进路,坚持意向性的不可还原性。但对于为什么意向性不可还原,两位哲学家却给出了不同的回答。

关键词：观念论意向性还原论不可还原性

Analysis of Differences in Inductance of Ni-Cu-Zn Ferrite Chip Inductors during the Plating Process

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Journal of Chemistry and Chemical Engineering 2014年第12期8卷 1125-1134页

作者： Yin-Lai Chai Shih-Feng Chien wen-Hsi Lee Chin-Pei lin wen-yu lin Pei-Yi Wei Department of Jewelry Technology Dahan Institute of Technology Hualien County 97145 Taiwan (R. O. C.) Department of Electrical Engineering Cheng Kung University Tainan City 701 Taiwan (R. O. C.) Cyntec Co. LTD. Hsinchu County 30076 Taiwan (R.O.C.)

Although plating is a necessary process for SMT components, it alters the magnetic characteristics and inductance level of Ni-Cu-Zn ferrite components. The results of this work show that the following three factors in plating affect these components, and the effects are different for Ni- and Sn-plating：（1） Plating layers exert stresses and react with the residual stress of components to change the inductance level, and the effect of the tin layer is greater than that of the nickel one; （2） The plating current induces a magnetic field inside the components directly and indirectly, and this remains as remanence inside the components and reduces the inductance level, and the effect level of Ni-plating is greater than that of Sn-plating; （3） The plating solution corrodes the interface of the termination and ferrite core of the components to release the residual stress, and causes an increase in inductance, and the effect of Sn-plating is greater than that of Ni-plating. In addition, the inductance level is the result of the net effect of these three factors, and if the sintering temperature is increased to change in the type of residual stress, the net effect will be changed.

关键词： Plating ferrite stress inductors

笛卡尔与认知规范性——论笛卡尔知识论的另一个面相

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科学技术哲学研究 2016年第4期33卷 26-30页

作者：文玉林复旦大学哲学院上海200433

长期以来,笛卡尔知识论被理解为经典基础主义,随着经典基础主义的基本原则被抛弃,笛卡尔知识论似乎仅具有历史意义。然而,经典基础主义只是笛卡尔知识论的一个面相,笛卡尔知识论最具创造性的部分是关于认知规范性的论述,笛卡尔认知规范... 详细信息

长期以来,笛卡尔知识论被理解为经典基础主义,随着经典基础主义的基本原则被抛弃,笛卡尔知识论似乎仅具有历史意义。然而,经典基础主义只是笛卡尔知识论的一个面相,笛卡尔知识论最具创造性的部分是关于认知规范性的论述,笛卡尔认知规范性理论支配着当代知识论中知识的规范性与知识的自然化之争。

关键词：经典基础主义认知辩护义务论自然化知识

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托马斯·里德论意向性

科学技术哲学研究 2014年第5期31卷 44-48页

作者：文玉林华东师范大学哲学系上海200241

近代西方哲学中的观念论是一种意向性还原理论,苏格兰哲学家托马斯·里德系统地反驳了观念论的意向性还原,他积极地描述心灵的意向性特征,并承认心灵的非意向性活动,尽管里德并没有提出一种理论来说明心灵的意向性特征,但他使意向性问... 详细信息

近代西方哲学中的观念论是一种意向性还原理论,苏格兰哲学家托马斯·里德系统地反驳了观念论的意向性还原,他积极地描述心灵的意向性特征,并承认心灵的非意向性活动,尽管里德并没有提出一种理论来说明心灵的意向性特征,但他使意向性问题更加突出。

关键词：观念意向性还原感觉设想

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang yu-wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

A Study of the Stress Induced during Manufacturing Processes of Chip Inductors

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材料科学与工程（中英文A版） 2015年第1期5卷 1-7页

作者： Yin-Lai-Chai Shih-Feng Chien wen-Ting Chen wen-Hsi Lee Pei-Yi Wei wen-yu lin Po-Chih Shen Department of Jewelry Technology Dahan Institute of Technology Hualien County 97145 Taiwan (R. O. C.) Department of Electrical Engineering National Cheng Kung University Tainan 701 Taiwan (R.O.C.) Cyntec Co. LTD. Hsinchu County 30076 Taiwan (R.O.C.)

Hepatitis C virus infections and genotypes in China

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Hepatobiliary & Pancreatic Diseases International 2002年第2期1卷 194-201页

作者： yuan-Ding Chen Ming-Ying Liu wen-lin yu Jia-Qi Li Mei Peng Qing Dai Xiao Liu Zhen-Quan Zhou From the Central Laboratory, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming 650118, China Kunming Hospital for Infectious Diseases, Kunming 650041, China Central Laboratory Institute of Medical Biology Chinese Academy of Medical Sciences & Peking Union Medical College Kunming 650118 China. chenyd@***

Objective: To define the conditions of hepatitis C vi- rus (HCV) infections, and geographic and demo- graphic distributions of genotypes in China. Methods: HCV infected patients were selected from individuals with different patterns of liver diseases and high risk populations in different parts of China. Genotypes of HCV in some isolates were further ana- lyzed, based on the data from our laboratory studies and some carefully selected published literatures. Results: The anti-HCV positive rates were 9.7% in patients with acute hepatitis, 13.3% in patients with chronic hepatitis, 18.3% in patients with hepatocel- lular carcinoma, 33.0% in patients with liver cirrho- sis, and 43.2% in patients with posttransfusional hepatitis (average, 16.2% in patients with liver di- seases). The anti-HCV positive rates in the high risk populations were 36.4% in leukemic patients, 43.0% in hemodialysis patients, 12.7% in blood do- nors, 64.1% in drug abusers, 13.1% in prostitutes, and 2.57% in naturally healthy people. At least 4 clades (clades 1, 2, 3 and 6) of HCV were found in China with different geographic and demographic distributions. Genotype 1b was the most widely dis- tributed genotype, and genotype 3 was mainly found in yunnan Province, Southwest China. Conclusion: China has a high incidence of HCV in- fection. Our results will provide a strategic basis for diagnosis, treatment and possibly prophylaxis of he- patitis C virus diseases.

关键词： HCV infections genotypes China

Broadband and perfect terahertz absorber based on multilayer metamaterial with cross-ring patterned structures

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Optoelectronics Letters 2025年第1期21卷 1-6页

作者： wen Jin LIU Zhanzhi WU Zhengwei PAN yu ZHANG Ying School of Science Xi'an Shiyou University Shaanxi Key Laboratory of Measurement and Control Technology for Oil and Gas Wells

Broadband and perfect terahertz absorber based on multilayer metamaterial using cross-ring patterned structures is proposed and investigated. The structure of the absorber is double absorption layers consisting of a chromium cross ring and eight isosceles right triangles. The unique structure of the double absorbing layers excites the electric dipole multimode resonance, giving rise to high absorption performance. Meanwhile, the influence of construal parameters on absorber behavior is also discussed. The numerical results show that the absorption achieves over 90% ranging from 2.45 THz to 6.25 THz and 99% absorption in the range of 3.7—5.3 THz. The realization of broadband and perfect absorber is described using the impedance matching principle. It is obviously found that the absorber is insensitive to the high angle of incidence for both transverse electric(TE) and transverse magnetic(TM) polarizations. Compared with the former reports, this absorber has remarkable improved absorption efficiency and smaller period. The terahertz absorber may be found applications in the fields of energy capture and thermal detection.

关键词： Metamaterials

Boosting bidirectional sulfur conversion enabled by introducing boron-doped atoms and phosphorus vacancies in Ni2P for lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 760-769页

作者： lin Peng yu Bai Hang Li Meixiu Qu Zhenhua Wang Kening Sun Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing Key Laboratory of Chemical Power Source and Green Catalysis School of Chemistry and Chemical Engineering Beijing Institute of Technology

Lithium-sulfur （Li-S） batteries have gained great attention due to the high theoretical energy density and low cost,yet their further commercialization has been obstructed by the notorious shuttle effect and sluggish redox ***,we supply a strategy to optimize the electron structure of Ni2P by concurrently introducing B-doped atoms and P vacancies in Ni2P （Vp-B-Ni2P）,thereby enhancing the bidirectional sulfur *** study indicates that the simultaneous introduction of B-doped atoms and P vacancies in Ni2P causes the redistribution of electron around Ni atoms,bringing about the upward shift of d-band center of Ni atoms and effective d-p orbital hybridization between Ni atoms and sulfur species,thus strengthening the chemical anchoring for lithium polysulfides （LiPSs） as well as expediting the bidirectional conversion kinetics of sulfur ***,theoretical calculations reveal that the incorporation of B-doped atoms and P vacancies in Ni2P selectively promotes Li2S dissolution and nucleation ***,the Li-S batteries with Vp-B-Ni2P-separators present outstanding rate ability of 777 m A h g-1at 5 C and high areal capacity of 8.03 mA h cm-2under E/S of 5μL mg-1and sulfur loading of 7.20 mg *** work elucidates that introducing heteroatom and vacancy in metal phosphide collaboratively regulates the electron structure to accelerate bidirectional sulfur conversion.

关键词： Lithium sulfur batteries