检索结果-南通市图书馆

Effectiveness of co-treatment with traditional Chinese medicine and letrozole for polycystic ovary syndrome:a meta-analysis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2017年第2期15卷 95-101页

作者： Qian-wen ma Yong Tan The First Clinical Medical College Nanjing University of Chinese Medicine Department of Gynecology Zhenjiang Hospital of Traditional Chinese Medicine

BACKGROUND： Polycystic ovary syndrome （PCOS） is an endocrine disease that affects gynecologica health. Treatment of PCOS remains a big challenge for clinicians. OBJECTIVE： This meta-analysis was developed to compare the efficacy of co-treatment with traditiona Chinese medicine （TCM） and letrozole against letrozole monotherapy in the treatment of PCOS. SEARCH STRATEGY： Randomized controlled trials （RCTs） were electronically retrieved from PubMed, Cochrane Library, China Biomedical Literature Database, China National Knowledge Infrastructure and Wanfang Data; related papers that were not available electronically were manually checked. All papers were assessed according to the Cochrane Handbook for Systematic Reviews of Interventions and the valid data were analyzed using Revman software （The Cochrane Collaboration, Copenhagen, Denmark） INCLUSION CRITERIA： We included RCTs that compared co-treatment with TCM and letrozole against letrozole monotherapy in women with PCOS, which was defined by anovulation, biochemical or clinical hyperandrogenemia and polycystic ovaries. We included trials from all sources. DATA EXTRACTION AND ANALYSIS： Two independent reviewers extracted data, and evaluated study quality according to the Cochrane Handbook for Systematic Reviews of Interventions criteria for RCT, including issues of patient randomization, blinding and bias. RESULTS： Eight RCTs, involving a total of 537 patients, were included in the present study. The meta-analysis showed that the cycle ovulation rate, the pregnancy rate and the total effective rate of symptom treatment were higher in treatments combining TCM with letrozole, compared with letrozole monotherapy. Although the rate of luteinizing hormone （LH）/follicle-stimulating hormone （FSH） and the body mass index of the group receiving combined therapy were lower than in letrozole monotherapy, no statistical difference was found in the LH and FSH level between the two groups. CONCLUSION： Available evidence showed that c

关键词： medicine, Chinese traditional letrozole polycystic ovary syndrome meta-analysis

Some Class 1 Graphs on gc-colorings

在线全文

学校读者我要写书评

暂无评论

Acta mathematica Sinica,English Series 2016年第10期32卷 1237-1245页

作者： Hua wen ma Xia ZHANG School of mathematical Sciences Shandong Normal UniversityJi'nan 250014P·R·China

An edge-coloring of a graph G is an coloring of a graph G is an edge-coloring of G such assignment of colors to all the edges of G. A go- that each color appears at each vertex at least g（v） times. The maximum integer k such that G has a go-coloring with k colors is called the gc-chromatic index of G and denoted by X＇gc （G）. In this paper, we extend a result on edge-covering coloring of Zhang X＇gc（） = δg（G）, and Liu in 2011, and give a new sufficient condition for a simple graph G to satisfy ＇ x＇gc（G）=δg（G）,where δg（G）=minv∈V（G）{[d（v）/g（v）]}.

关键词： Edge-coloring go-coloring go-chromatic index edge covering classification problem

Integrable nonlocal PT-symmetric generalized so(3,R)-mKdV equations

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2023年第12期75卷 19-24页

作者： Shou-Ting Chen wen-Xiu ma School of mathematics and Statistics Xuzhou University of TechnologyXuzhou 221008JiangsuChina Department of mathematics Zhejiang Normal UniversityJinhua 321004ZhejiangChina Department of mathematics King Abdulaziz UniversityJeddah 21589Saudi Arabia Department of mathematics and Statistics University of South FloridaTampaFL 33620-5700United States of America School of mathematical and Statistical Sciences North-West UniversityMafikeng CampusPrivate Bag X2046Mmabatho 2735South Africa

Based on a soliton hierarchy associated with so(3,R),we construct two integrable nonlocal PT-symmetric generalized mKdV *** key step is to formulate two nonlocal reverse-spacetime similarity transformations for the involved spectral matrix,and therefore,integrable nonlocal complex and real reverse-spacetime generalized so(3,R)-mKdV equations of fifth-order are *** resulting reduced nonlocal integrable equations inherit infinitely many commuting symmetries and conservation laws.

关键词： integrable equation lax pair nonlocal reduction PT-symmetry zero curvature equation

Constructing Donor–Acceptor‑Linked COFs Electrolytes to Regulate Electron Density and Accelerate the Li^(+)Migration in Quasi‑Solid‑State Battery

在线全文

学校读者我要写书评

暂无评论

Nano-Micro letters 2025年第1期17卷 456-471页

作者： Genfu Zhao Hang ma Conghui Zhang Yongxin Yang Shuyuan Yu Haiye Zhu Yongjiang Sun Hong Guo School of materials and Energy International Joint Research Center for Advanced Energy Materials of Yunnan ProvinceYunnan UniversityKunming 650091People’s Republic of China Yunnan Yuntianhua Co. LtdR&D CenterKunming 650228People’s Republic of China Southwest United Graduate School Kunming 650091People’s Republic of China

Regulation the electronic density of solid-state electrolyte by donor–acceptor(D–A)system can achieve highly-selective Li^(+)transportation and conduction in solid-state Li metal *** study reports a high-performance solid-state electrolyte thorough D–A-linked covalent organic frameworks(COFs)based on intramolecular charge transfer *** other reported COFbased solid-state electrolyte,the developed concept with D–A-linked COFs not only achieves electronic modulation to promote highly-selective Li^(+)migration and inhibit Li dendrite,but also offers a crucial opportunity to understand the role of electronic density in solid-state Li metal *** introduced strong electronegativity F-based ligand in COF electrolyte results in highlyselective Li^(+)(transference number 0.83),high ionic conductivity(6.7×10^(-4)S cm^(−1)),excellent cyclic ability(1000 h)in Li metal symmetric cell and high-capacity retention in Li/LiFePO_(4)cell(90.8%for 300 cycles at 5C)than substituted C-and N-based *** is ascribed to outstanding D–A interaction between donor porphyrin and acceptor F atoms,which effectively expedites electron transferring from porphyrin to F-based ligand and enhances Li^(+)***,we anticipate that this work creates insight into the strategy for accelerating Li^(+)conduction in high-performance solid-state Li metal batteries through D–A system.

关键词： Electronic modulation engineering Donor-acceptor-linked covalent organic frameworks Quasi-solid-state Li metal battery

The Citron homology domain of maP4Ks improves outcomes of traumatic brain injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3233-3244页

作者： Xiaoling Zhong wenjiao Tai Meng-Lu Liu Shuaipeng ma Tianjin Shen Yuhua Zou Chun-Li Zhang Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTXUSA Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTXUSA Peter O’Donnell Jr.Brain Institute University of Texas Southwestern Medical CenterDallasTXUSA

The mitogen-activated protein kinase kinase kinase kinases(maP4Ks)signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following *** targeting this pathway is beneficial to brain injury remains *** this study,we showed that adeno-associated virus-delivery of the Citron homology domain of maP4Ks effectively reduces traumatic brain injury-induced reactive gliosis,tauopathy,lesion size,and behavioral *** inhibition of maP4Ks replicated the ameliorative effects observed with expression of the Citron homology ***,the Citron homology domain acted as a dominant-negative mutant,impeding maP4K-mediated phosphorylation of the dishevelled proteins and thereby controlling the Wnt/β-catenin *** findings implicate a therapeutic potential of targeting maP4Ks to alleviate the detrimental effects of traumatic brain injury.

关键词： adeno-associated virus Citron homology Citron homology domain gene therapy mitogen-activated protein kinase kinase kinase kinases traumatic brain injury

Analysis of Crystallization Behavior of Mold Fluxes Containing TiO_2 Using Single Hot Thermocouple Technique

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2016年第4期23卷 322-328页

作者： Yun leI Bing XIE wen-hui ma State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Kunming University of Science and Technology College of materials Science and Engineering Chongqing University

The crystallization behavior of mold fluxes containing 0-8 mass% TiO2 was investigated using the single hot therrnocouple technique （SHTT） and X ray diffraction （XRD） to study the possible effects on the coordination of heat transfer control and strand lubrication for casting crack sensitive peritectic steels. Time-temperature-transforma tion （TTT） and continuous-cooling transformation （CCT） curves were plotted using the data obtained from SHTT to characterize the crystallization of the mold fluxes. The results showed that crystallization of the mold fluxes during isothermal and non-isothermal processes was suppressed with TiO2 addition. From the TTT curves, it could be seen that the incubation and growth time of crystallization increased significantly with TiO2 addition. The CCT curves showed that the crystallization temperature initially decreased, and then suddenly increased with increasing the TiO2 content. XRD analysis suggested the presence of cuspidine in the mold fluxes with lower TiO2 content （〈4 mass%） , while both perovskite and cuspidine were detected in the mold fluxes when the TiO2 content was increased to 8 mass%. In addition, the growth mechanisms of the crystals changed during the isothermal crystallization process from interface controlled growth to diffusion-controlled growth with increasing the TiO2 content.

关键词： mold flux single hot thermocouple technique kinetics crystallization TTT curve CCT curve

Hypidone hydrochloride(YL-0919)ameliorates functional deficits after traumatic brain injury in mice by activating the sigma-1 receptor for antioxidation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2325-2336页

作者： Yafan Bai Hui ma Yue Zhang Jinfeng Li Xiaojuan Hou Yixin Yang Guyan Wang Yunfeng Li Department of Anesthesiology Beijing Tongren HospitalCapital Medical UniversityBeijingChina Beijing Institute of Basic Medical Sciences BeijingChina Hebei North University ZhangjiakouHebei ProvinceChina Beijing Institute of Pharmacology and Toxicology State Key Laboratory of Toxicology and Medical CountermeasuresBeijing Key Laboratory of NeuropsychopharmacologyBeijingChina

Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary *** this study,we evaluated hypidone hydrochloride(YL-0919),a self-developed antidepressant with selective sigma-1 receptor agonist properties,and its associated mechanisms and targets in traumatic brain *** experiments to assess functional deficits were followed by assessment of neuronal damage through histological analyses and examination of blood-brain barrier permeability and brain ***,we investigated the antioxidative effects of YL-0919 by assessing the levels of traditional markers of oxidative stress in vivo in mice and in vitro in HT22 ***,the targeted action of YL-0919 was verified by employing a sigma-1 receptor antagonist(BD-1047).Our findings demonstrated that YL-0919 markedly improved deficits in motor function and spatial cognition on day 3 post traumatic brain injury,while also decreasing neuronal mortality and reversing blood-brain barrier disruption and brain ***,YL-0919 effectively combated oxidative stress both in vivo and in *** protective effects of YL-0919 were partially inhibited by *** results indicated that YL-0919 relieved impairments in motor and spatial cognition by restraining oxidative stress,a neuroprotective effect that was partially reversed by the sigma-1 receptor antagonist ***-0919 may have potential as a new treatment for traumatic brain injury.

关键词： antidepressant drug blood-brain barrier cognitive function hypidone hydrochloride(YL-0919) neurological function nuclear factor-erythroid 2 related factor 2 oxidative stress sigma-1 receptor superoxide dismutase traumatic brain injury

A surface engineering strategy for the stabilization of zinc metal anodes with montmorillonite layers toward long-life rechargeable aqueous zinc ion batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 94-105页

作者： wenbo Wang Ruifeng Xu Xu Zhang Peiyu Wang Bao Yang Bingjun Yang Juan Yang Kailimai Su Pengjun ma Yanan Deng Xianfeng Fan Wanjun Chen Key Laboratory for Electronic materials College of Electrical Engineering Northwest Minzu University Resource Chemistry and Energy materials Research Center State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical Physics Chinese Academy of Sciences University of Chinese Academy of Sciences Institute for materials and Processes School of Engineering University of Edinburgh

Rechargeable aqueous zinc-ion batteries （AZIBs） exhibit appreciable potential in the domain of electrochemical energy ***,there are serious challenges for AZIBs,for instance zinc dendrite growth,hydrogen evolution reaction （HER）,and corrosion side ***,we propose a surface engineering modification strategy for coating the montmorillonite （MMT） layer onto the surface of the Zn anode to tackle these issues,thereby achieving high cycling stability for rechargeable *** results reveal that the MMT layer on the surface of the Zn anode is able to provide ordered zincophilic channels for zinc ions migration,facilitating the reaction kinetics of zinc *** functional theory（DFT） calculations and water contact angle （CA） tests prove that MMT@Zn anode exhibits superior adsorption capacity for Zn2+and better hydrophobicity than the bare Zn anode,thereby achieving excellent cycling ***,the MMT@Zn||MMT@Zn symmetric cell holds the stable cycling over 5600 h at 0.5 ma cm-2and 0.125 m A h cm-2,even exceeding 1800 h long cycling under harsh conditions of 5 m A cm-2and 1.25 m A h *** MMT@Zn||V2O5full cell reaches over 3000 cycles at 2 A g-1with excellent rate ***,this surface engineering modification strategy for enhancing the electrochemical performance of AZIBs represents a promising application.

关键词： Surface engineering strategy Montmorillonite layer Protection mechanism of Zn anode Cycling stability Aqueous zinc ion batteries

Wear Resistance, Cytotoxicity and Antibacterial Properties of Polyetheretherketone Composite Modified by Carbon Fiber and Black Phosphorus

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2022年第1期19卷 155-166页

作者： Jingdan Li Qian Liang wen Qin Jing ma School of material Science and Engineering Taiyuan University of TechnologyTaiyuan030024China

High wear resistance,low cytotoxicity and excellent antibacterial properties are the basis for osseointegration of implant ***(PEEK)has been considered as a potential implant material due to its excellent biocompatibility,natural radiolucency and mechanical *** this work,to improve the wear resistance,cytotoxicity and antibacterial properties of PEEK,carbon fiber(CFR)and Black Phosphorus(BP)were used to synergistically modify PEEK by two methods,deposition of BP coating on CFR-PEEK and BP/CFR-PEEK coating on Ti6Al4V(TC4)through electrostatic *** CFR and BP synergistically modified PEEK,the friction coefficient of BP coating on CFR-PEEK and BP/CFR-PEEK coating were 0.14±0.01 and 0.09±0.02,*** wear volume of BP coating on CFR-PEEK(30.54±1.32)was higher than that of BP/CFR-PEEK coating(9.46±1.32),which indicated that BP/CFR-PEEK coating showed high wear *** difference in wear resistance may be caused by the fact that BP was not easily oxidized in BP/CFR-PEEK *** addition,BP coating on CFR-PEEK and BP/CFR-PEEK coating showed no obvious cytotoxicity to L929 cell and presented excellent antibacterial efficiency(up to 94.5%±2.8%and 96.0%±3.8%,respectively)against Staphylococcus aureus(***).It was concluded that BP/CFR-PEEK coating exhibited high wear resistance,low cytotoxicity and excellent antibacterial properties against ***,which might provide a foundation for osseointegration of implants.

关键词： Surface deposition Electrostatic spraying Wear resistance Cytotoxicity Antibacterial properties