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蒲河流域河流生境质量综合评价及其与水质响应关系

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生态学杂志 2015年第2期34卷 516-523页

作者：王琼范志平李法云鞠文鹏辽宁石油化工大学生态环境研究院辽宁抚顺113001 湖南农业大学资源环境学院长沙410128 辽宁省抚顺市林业科学研究所辽宁抚顺113008

河流生境是河流生物赖以生存的环境,是维持河流生态完整性、维护河流健康的重要因素。本文结合蒲河流域环境特点,运用层次分析法建立了蒲河流域河流生境质量评价体系,对流域内25个河段的生境质量状况进行了综合评价,并进一步分析了河流... 详细信息

河流生境是河流生物赖以生存的环境,是维持河流生态完整性、维护河流健康的重要因素。本文结合蒲河流域环境特点,运用层次分析法建立了蒲河流域河流生境质量评价体系,对流域内25个河段的生境质量状况进行了综合评价,并进一步分析了河流生境综合评价指数与河流水质的相关关系。结果表明:(1)蒲河流域25个河段的生境质量状况差异显著,其中1个河段的生境质量等级为好,5个河段为较好等级,16个河段为一般等级,3个河段为较差等级。(2)生境综合评价指数与TP、NH4+-N、CODCr呈负相关,生境质量评价体系中其他指标也与水质指标具有相关性,表明生境质量是影响水质的重要因素。

关键词：生境质量综合评价水质蒲河流域层次分析

Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui Liu Chao Fang Qiuxia peng wen Qin Xuebing Yan Kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan Li peng Hao Hongmei Duan Fei Hao wen Zhao Yudan Gao Zhaoyang Yang Kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang ju-Yun Ma peng-peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

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一种改进的协同中继节点选择算法

计算机应用研究 2008年第12期25卷 3816-3818页

作者：闻鹏举易辉跃赵晓群徐尚志同济大学电子与信息工程学院上海200092 上海无线通信研究中心上海200050

机会主义中继选择算法(ORS)基于瞬时信道质量选择一个最优中继节点帮助源节点进行协同通信,可以取得与其他复杂协议相同的分集阶次;但该算法存在碰撞问题,其采取的退避机制会增加网络延时。为此,提出一种碰撞时的改进处理方法,可以避免... 详细信息

机会主义中继选择算法(ORS)基于瞬时信道质量选择一个最优中继节点帮助源节点进行协同通信,可以取得与其他复杂协议相同的分集阶次;但该算法存在碰撞问题,其采取的退避机制会增加网络延时。为此,提出一种碰撞时的改进处理方法,可以避免延时,提高网络容量。仿真结果表明,与原方法相比,该方法在保证BER性能时可有效地提高吞吐量。

关键词：中继碰撞协同分集

Visualization of the protective role of estrogen against female liver fibrosis via an ER viscosity NIR fluorescent probe

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Science China Chemistry 2025年第1期 360-368页

作者： Zheng Liu Changyu Zhang Zipeng Li Wanying Ma Jia Liu Xiang Xia Ning Xu wen Sun Jianjun Du Jiangli Fan Xiaojun peng State Key Laboratory of Fine Chemicals Dalian University of Technology Ningbo Institute of Dalian University of Technology

Endoplasmic reticulum(ER) viscosity has emerged as a new potential biomarker for hepatic fibrosis(HF). Herein, we report the first ER-targeting viscosity-responsive near-infrared(NIR) fluorescent probe HBT-PP for investigations of HF *** twisted intramolecular charge transfer(TICT) and the excited state intramolecular proton transfer(ESIPT) are combined to endow HBT-PP with the selective response towards viscosity(～62-fold) and a super large stokes shift(～320 nm). HBT-PP mainly targets organelle ER and is able to image the drug-or alcohol-induced viscosity elevation in living cells. Significantly,HBT-PP was successfully applied to visualize the gender difference in HF and the protective role of estrogen in restraining HF progression. Of note, after 10 min of stain with HBT-PP, HF lesions showed a stage-based response, indicating the potential of this probe in fast and early diagnosis of HF. These results clearly demonstrated the promising application of HBT-PP as a new tool for exploring ER viscosity-involved physiological and pathological processes.

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Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li wen‑Xia Su Jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

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胡杨多态叶光合速率与荧光特性的比较研究

吉林林业科技 2005年第3期34卷 19-21页

作者：邱箭郑彩霞于文鹏北京林业大学生物学院北京100083

成年胡杨叶片为多态形,呈现从披针形到锯齿卵圆形的规律性变化。为揭示多态叶发育变化的生态适应机制,本文选择锯齿卵圆形、卵圆形和披针形三种典型叶,采用PPS便携式光合仪和PAM2100荧光仪对胡杨多态叶进行光合特性的比较发现,胡杨三种... 详细信息

成年胡杨叶片为多态形,呈现从披针形到锯齿卵圆形的规律性变化。为揭示多态叶发育变化的生态适应机制,本文选择锯齿卵圆形、卵圆形和披针形三种典型叶,采用PPS便携式光合仪和PAM2100荧光仪对胡杨多态叶进行光合特性的比较发现,胡杨三种形态叶的光合速率、初始荧光、最大荧光和PSⅡ原初光能转换效率都存在显著差异。利用SDS-PAGE测得胡杨三种形态叶的Rubisco含量基本一致。研究结果表明,胡杨叶片在发育过程中在光合特性上也发生了变异,以适应其生境的变化。

关键词：胡杨多态叶荧光特性光合特性光合速率

氢化物发生-原子荧光光谱法测定食品中有机硒和无机硒

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食品科技 2016年第11期41卷 262-265页

作者：谢逸欣黄仕稳鞠鹤鹏陈丽璇吴晖曾婷广州军区疾病预防控制中心广州510507 华南理工大学轻工与食品学院广州510640

目的：建立食品中有机硒含量和无机硒含量的测定方法。方法：50%盐酸提取食品中无机硒成分,通过硝酸-高氯酸混合酸体系进行消解,测定无机硒含量。有机硒含量通过总硒与无机硒含量差减法获得。结果：硒的检出限是0.0028 mg/kg,线性范围是... 详细信息

目的：建立食品中有机硒含量和无机硒含量的测定方法。方法：50%盐酸提取食品中无机硒成分,通过硝酸-高氯酸混合酸体系进行消解,测定无机硒含量。有机硒含量通过总硒与无机硒含量差减法获得。结果：硒的检出限是0.0028 mg/kg,线性范围是（0～10）ng/mL。经回收实验与实际样品检测,总硒加标回收率为83.82%～101.46%,相对标准偏差（RSD）为0.75%～3.79%;无机硒加标回收率为97.95%～102.47%,相对标准偏差（RSD）为0.64%～4.10%。结论：该测定方法线性范围广、重复性好、检出限低,适合用于测定食品中有机硒及无机硒含量。

关键词：氢化物发生-原子荧光光谱法有机硒无机硒食品